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ONTOLOGY REPORT - ANNOTATIONS


Term:NAD binding
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Accession:GO:0051287 term browser browse the term
Definition:Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
Synonyms:exact_synonym: nicotinamide adenine dinucleotide binding
 related_synonym: NAD or NADH binding
 alt_id: GO:0051288


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NAD binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07005667.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07006451.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07013200.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07021086.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07022022.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07024795.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07025010.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07028691.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07028748.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07030729.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07032317.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07032392.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07034329.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07034445.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07053879.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07070043.1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G AABR07071101.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AC107446.2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AC110981.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G Adh1 alcohol dehydrogenase 1 (class I) IDA RGD PMID:10094961, PMID:1558299 RGD:1642948, RGD:1642949 NCBI chr 2:226,797,303...226,808,892 JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IDA
ISO
(PMID:10407146) RGD PMID:10407146, PMID:2774584 RGD:1358222 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IDA RGD PMID:10829036 RGD:631904 NCBI chr 2:226,748,724...226,763,183 JBrowse link
G Ahcy adenosylhomocysteinase IDA RGD PMID:2910349 RGD:1598902 NCBI chr 3:143,569,134...143,584,359 JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 enables ISS PMID:12693930 CAFA PMID:12693930 RGD:12793038 NCBI chr 1:218,000,470...218,152,962 JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 enables ISS PMID:12693930 CAFA PMID:12693930 RGD:12793038 NCBI chr 1:218,201,443...218,241,410 JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 IDA RGD PMID:12871571, PMID:12527414, PMID:7262085 RGD:1304407, RGD:1600514, RGD:1600512 NCBI chr17:40,132,339...40,158,677 JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IDA RGD PMID:10467734 RGD:2313412 NCBI chr13:79,505,738...79,522,539 JBrowse link
G Aox1 aldehyde oxidase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:59,579,621...59,658,772 JBrowse link
G Aox2 aldehyde oxidase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:59,828,403...59,916,175 JBrowse link
G Aox3 aldehyde oxidase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:59,664,784...59,749,814 JBrowse link
G Aox4 aldehyde oxidase 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:59,761,238...59,818,169 JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 enables ISO
IEA
(PMID:16380372)
GO_REF:0000107
RGD
Ensembl
PMID:16380372 GO_REF:0000107 NCBI chr 2:223,702,410...223,723,076 JBrowse link
G Ctbp1 C-terminal binding protein 1 enables IDA
IEA
PMID:19351597
GO_REF:0000002
InterPro PMID:19351597 GO_REF:0000002, RGD:8553313 NCBI chr14:77,455,580...77,482,821 JBrowse link
G Ctbp2 C-terminal binding protein 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:187,782,064...187,918,115 JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 IDA RGD PMID:14609324 RGD:1599772 NCBI chr 7:114,306,686...114,324,247 JBrowse link
G Dld dihydrolipoamide dehydrogenase IDA RGD PMID:3753688 RGD:2289893 NCBI chr 6:47,904,153...47,924,814 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:157,962,312...157,967,158 JBrowse link
G Gapdh-ps2 glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr16:24,029,979...24,031,270 JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic enables IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr 1:85,979,096...85,994,153 JBrowse link
G Glyr1 glyoxylate reductase 1 homolog enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:10,532,036...10,567,639 JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 IDA RGD PMID:9550546 RGD:1641824 NCBI chr 7:130,842,526...130,851,530 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:114,591,103...114,620,771 JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase IDA RGD PMID:2689175 RGD:1599320 NCBI chr 5:59,234,179...59,243,614 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IDA RGD PMID:1730633 RGD:1600572 NCBI chr 6:26,187,969...26,227,605 JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:81,649,180...81,747,244 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase enables ISO
ISS
(PMID:10198228), (PMID:15581601)
GO_REF:0000024
RGD
UniProt
PMID:10198228 PMID:15581601 GO_REF:0000024 NCBI chr16:33,986,265...34,024,228 JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IDA RGD PMID:15761036 RGD:1625105 NCBI chr19:33,397,656...33,402,899 JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IDA RGD PMID:11023795 RGD:2302237 NCBI chr  X:21,089,152...21,091,597 JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IDA RGD PMID:1955079 RGD:1625116 NCBI chr 2:186,169,864...186,175,984 JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:66,534,146...66,563,703 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:134,038,644...134,057,969 JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha enables IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 8:54,971,694...54,991,085 JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:117,481,845...117,486,909 JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma enables IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr  X:151,515,244...151,524,175 JBrowse link
G Ldha lactate dehydrogenase A IDA RGD PMID:17447164 RGD:1624966 NCBI chr 1:97,371,823...97,381,247 JBrowse link
G Ldhb lactate dehydrogenase B IDA RGD PMID:17447164 RGD:1624966 NCBI chr 4:175,428,382...175,446,403 JBrowse link
G LOC108349792 glyceraldehyde-3-phosphate dehydrogenase pseudogene enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:216,612,021...216,613,034 JBrowse link
G LOC108351137 glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000104 UniProt GO_REF:0000104
G LOC108352348 glyceraldehyde-3-phosphate dehydrogenase pseudogene enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr11:68,857,943...68,859,024 JBrowse link
G LOC303448 similar to glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:75,960,507...75,968,953 JBrowse link
G Mdh1 malate dehydrogenase 1 enables IDA
ISO
(PMID:10075524) RGD PMID:10075524, PMID:17447164 RGD:1624966 NCBI chr14:95,630,625...95,645,920 JBrowse link
G Me1 malic enzyme 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:87,549,043...87,660,251 JBrowse link
G Me2 malic enzyme 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:67,350,833...67,400,987 JBrowse link
G Me3 malic enzyme 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:143,534,024...143,735,551 JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:83,654,402...83,671,474 JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:201,300,365...201,305,461 JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:51,411,413...51,505,125 JBrowse link
G Nudt6 nudix hydrolase 6 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:120,289,908...120,306,197 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IDA RGD PMID:16302026, PMID:15857403 RGD:1601079, RGD:1601082 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Phgdh phosphoglycerate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:185,906,964...185,936,160 JBrowse link
G RGD1560826 similar to glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:210,784,633...210,785,652 JBrowse link
G Sord sorbitol dehydrogenase enables ISO (PMID:12962626) RGD PMID:12962626 NCBI chr 3:109,184,697...109,216,133 JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:42,848,704...42,872,351 JBrowse link
NAD+ binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 enables IEA
ISO
GO_REF:0000107
(MGI:3692370|PMID:16241904)
Ensembl
RGD
PMID:16241904 GO_REF:0000107 MGI:3692370 NCBI chr 1:119,982,272...120,017,416 JBrowse link
G Cryl1 crystallin, lambda 1 enables ISS
ISO
GO_REF:0000024
(PMID:15809331)
UniProt
RGD
PMID:15809331 GO_REF:0000024 NCBI chr15:31,427,011...31,545,997 JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:79,241,927...79,275,173 JBrowse link
G Glud1 glutamate dehydrogenase 1 enables ISO (PMID:12193607) RGD PMID:12193607 NCBI chr16:9,640,312...9,673,961 JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase enables ISS
ISO
GO_REF:0000024
(PMID:10840044)
UniProt
RGD
PMID:10840044 GO_REF:0000024 NCBI chr 2:219,787,935...219,830,335 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:26,187,969...26,227,605 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase enables ISO
ISS
(PMID:16828555), (PMID:21072165)
GO_REF:0000024
RGD
UniProt
PMID:16828555 PMID:21072165 GO_REF:0000024 NCBI chr16:33,986,265...34,024,228 JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 enables ISO (PMID:16061477) RGD PMID:16061477 NCBI chr11:64,902,848...64,934,916 JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 NOT|enables ISO (PMID:16061477) RGD PMID:16061477 NCBI chr11:64,780,977...64,814,995 JBrowse link
G Sirt1 sirtuin 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:25,307,143...25,329,260 JBrowse link
G Sirt2 sirtuin 2 enables ISO
IEA
IBA
(PMID:11427894)
GO_REF:0000104
PMID:21873635
RGD
UniProt
PMID:11427894, PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 1:84,053,883...84,076,975 JBrowse link
G Sirt3 sirtuin 3 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:195,942,066...195,964,472 JBrowse link
G Sirt4 sirtuin 4 enables IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr12:41,125,533...41,139,440 JBrowse link
G Sirt5 sirtuin 5 enables ISO
ISS
(PMID:21908771), (PMID:22076378)
GO_REF:0000024
RGD
UniProt
PMID:21908771 PMID:22076378 GO_REF:0000024 NCBI chr17:21,310,028...21,337,137 JBrowse link
G Sirt6 sirtuin 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:8,082,312...8,087,776 JBrowse link
G Sirt7 sirtuin 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:105,896,476...105,903,301 JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 enables ISO
IBA
(PMID:23072385)
PMID:21873635
RGD PMID:23072385, PMID:21873635 RGD:13792537 NCBI chr 9:653,740...731,121 JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 NOT|enables ISO (PMID:25635049) RGD PMID:25635049 NCBI chr 4:67,012,151...67,062,406 JBrowse link
NADH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:21276780 RGD:7241587 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Cryz crystallin zeta NOT|enables ISO
ISS
(PMID:17497241)
GO_REF:0000024
RGD
UniProt
PMID:17497241 GO_REF:0000024 NCBI chr 2:243,552,037...243,580,369 JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 enables ISO
ISS
(PMID:25203508)
GO_REF:0000024
RGD
UniProt
PMID:25203508 GO_REF:0000024 NCBI chr20:4,826,725...4,828,742 JBrowse link
G Qdpr quinoid dihydropteridine reductase enables IPI
IBA
PMID:21873635 RGD
GO_Central
PMID:8631945, PMID:21873635 RGD:5128583, RGD:13792537 NCBI chr14:65,670,251...65,683,853 JBrowse link
G Rnls renalase, FAD-dependent amine oxidase enables ISO (PMID:25531177) RGD PMID:25531177 NCBI chr 1:231,037,481...231,309,855 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19980
    binding 17008
      small molecule binding 2502
        nucleotide binding 2130
          NAD binding 94
            NAD+ binding 18
            NADH binding 5
Path 2
Term Annotations click to browse term
  molecular_function 19980
    binding 17008
      organic cyclic compound binding 5709
        nucleoside phosphate binding 2130
          nucleotide binding 2130
            NAD binding 94
              NAD+ binding 18
              NADH binding 5
paths to the root