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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051281 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: positive regulation of cytosolic release of sequestered calcium ion (Ca2+);   positive regulation of cytosolic release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytosol;   up regulation of release of sequestered calcium ion into cytosol;   upregulation of release of sequestered calcium ion into cytosol
 narrow_synonym: activation of release of sequestered calcium ion into cytosol;   stimulation of release of sequestered calcium ion into cytosol
 broad_synonym: positive regulation of calcium ion (Ca2+) mobilization;   positive regulation of calcium mobilization;   positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   positive regulation of cytoplasmic release of stored calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion into cytoplasm;   positive regulation of release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytoplasm



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positive regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:88319 (PMID:19228876) RGD PMID:19228876 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Aplnr apelin receptor involved_in ISO
ISS
(PMID:25639753)
GO_REF:0000024
RGD
UniProt
PMID:25639753 GO_REF:0000024 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (PMID:15947791) RGD PMID:15947791 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bdkrb1 bradykinin receptor B1 NOT IDA in nociceptive dorsal root ganglion neurons
in urinary bladder urothelium
RGD PMID:15319421 PMID:15576455 RGD:1625754, RGD:1625040 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Capn3 calpain 3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:3811664|PMID:18676612)
Ensembl
UniProt
RGD
PMID:18676612 GO_REF:0000024 GO_REF:0000107 MGI:3811664 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Casq1 calsequestrin 1 involved_in ISO
ISS
(PMID:28895244)
GO_REF:0000024
RGD
UniProt
PMID:28895244 GO_REF:0000024 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16672701), (PMID:9382888)
(MGI:1100180|PMID:9382888)
MGI:87859 (PMID:19228876)
RGD PMID:9382888 PMID:16672701 PMID:19228876 MGI:1100180 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23990668)
UniProt
RGD
PMID:23990668 GO_REF:0000024 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 acts_upstream_of_or_within ISO (PMID:12777403) RGD PMID:12777403 NCBI chr 4:156,462,742...156,486,240
Ensembl chr 4:156,462,742...156,486,240
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO UniProtKB:P35411 (PMID:10415068), (PMID:10869418) RGD PMID:10415068 PMID:10869418 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
ISS
(PMID:12782716)
GO_REF:0000024
RGD
UniProt
PMID:12782716 GO_REF:0000024 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:12782716)
UniProt
RGD
PMID:12782716 GO_REF:0000024 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Dbi diazepam binding inhibitor IMP RGD PMID:9804683 RGD:2316286 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO (PMID:1282671), (PMID:7838121) RGD PMID:1282671 PMID:7838121 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:12628492 RGD:728499 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA
(PMID:1672265), (PMID:19052258)
GO_REF:0000107
RGD
Ensembl
PMID:1672265 PMID:19052258 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
IEA
ISS
(PMID:1672265)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:1672265 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in ISO (PMID:18480058) RGD PMID:18480058 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:15705806)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3701833 (PMID:23133519), (PMID:26375174) RGD PMID:23133519 PMID:26375174 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267
JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20045483 RGD:4145470 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8187959 RGD:2292619 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Npsr1 neuropeptide S receptor 1 involved_in ISO
ISS
IEA
IBA
(PMID:16790440)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
RGD
UniProt
Ensembl
GO_Central
PMID:16790440 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:10799761 RGD:9743926 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA
(PMID:22454520)
GO_REF:0000107
RGD
Ensembl
PMID:22454520 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Plcg1 phospholipase C, gamma 1 involved_in ISO
IEA
(PMID:22454520)
GO_REF:0000107
RGD
Ensembl
PMID:22454520 GO_REF:0000107 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Snca synuclein alpha involved_in ISO
IEA
(PMID:15641770)
GO_REF:0000107
RGD
Ensembl
PMID:15641770 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) RGD PMID:22338092 MGI:5487506 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IDA PMID:2873512 UniProt PMID:2873512 RGD:8554039 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Trdn triadin IMP RGD PMID:21811790 RGD:7327228 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19052258)
Ensembl
RGD
PMID:19052258 GO_REF:0000107 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:7602097) RGD PMID:7602097 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    negative regulation of biological process 5757
      negative regulation of cellular process 5391
        negative regulation of sequestering of calcium ion 131
          release of sequestered calcium ion into cytosol 130
            positive regulation of release of sequestered calcium ion into cytosol 35
              positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
              positive regulation of ryanodine-sensitive calcium-release channel activity 0
Path 2
Term Annotations click to browse term
  biological_process 20292
    homeostatic process 1969
      chemical homeostasis 1204
        monoatomic ion homeostasis 673
          intracellular monoatomic ion homeostasis 590
            intracellular monoatomic cation homeostasis 579
              intracellular calcium ion homeostasis 339
                sequestering of calcium ion 135
                  regulation of sequestering of calcium ion 133
                    negative regulation of sequestering of calcium ion 131
                      release of sequestered calcium ion into cytosol 130
                        regulation of release of sequestered calcium ion into cytosol 79
                          positive regulation of release of sequestered calcium ion into cytosol 35
                            positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
                            positive regulation of ryanodine-sensitive calcium-release channel activity 0
paths to the root