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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051281 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: positive regulation of cytosolic release of sequestered calcium ion (Ca2+);   positive regulation of cytosolic release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytosol;   up regulation of release of sequestered calcium ion into cytosol;   upregulation of release of sequestered calcium ion into cytosol
 narrow_synonym: activation of release of sequestered calcium ion into cytosol;   stimulation of release of sequestered calcium ion into cytosol
 broad_synonym: positive regulation of calcium ion (Ca2+) mobilization;   positive regulation of calcium mobilization;   positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   positive regulation of cytoplasmic release of stored calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion into cytoplasm;   positive regulation of release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytoplasm



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positive regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:88319 (MGI:3839222|PMID:19228876) RGD PMID:19228876 MGI:3839222 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Aplnr apelin receptor involved_in ISO
ISS
(PMID:25639753)
GO_REF:0000024
RGD
UniProt
PMID:25639753 GO_REF:0000024 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857429 (MGI:3694443|PMID:15947791)
Ensembl
RGD
PMID:15947791 GO_REF:0000107 MGI:3694443 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bdkrb1 bradykinin receptor B1 NOT IDA in nociceptive dorsal root ganglion neurons
in urinary bladder urothelium
RGD PMID:15319421 PMID:15576455 RGD:1625754, RGD:1625040 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Capn3 calpain 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3811664|PMID:18676612)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18676612 GO_REF:0000024 GO_REF:0000107 MGI:3811664 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Casq1 calsequestrin 1 involved_in ISO
ISS
(PMID:28895244)
GO_REF:0000024
RGD
UniProt
PMID:28895244 GO_REF:0000024 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16672701), (PMID:9382888)
MGI:87859 (MGI:3839222|PMID:19228876)
(MGI:1100180|PMID:9382888)
RGD PMID:9382888 PMID:16672701 PMID:19228876 MGI:1100180 MGI:3839222 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23990668)
UniProt
RGD
PMID:23990668 GO_REF:0000024 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 acts_upstream_of_or_within ISO (MGI:3618731|PMID:12777403) RGD PMID:12777403 MGI:3618731 NCBI chr 4:156,462,742...156,486,240
Ensembl chr 4:156,462,742...156,486,240
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA
UniProtKB:P35411 (PMID:10415068), (PMID:10869418)
GO_REF:0000107
RGD
Ensembl
PMID:10415068 PMID:10869418 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
ISS
(PMID:12782716)
GO_REF:0000024
RGD
UniProt
PMID:12782716 GO_REF:0000024 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:12782716)
UniProt
RGD
PMID:12782716 GO_REF:0000024 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IMP RGD PMID:9804683 RGD:2316286 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO
IEA
(PMID:1282671), (PMID:7838121)
GO_REF:0000107
RGD
Ensembl
PMID:1282671 PMID:7838121 GO_REF:0000107 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:12628492 RGD:728499 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G F2 coagulation factor II involved_in ISO
IEA
(PMID:1672265), (PMID:19052258)
GO_REF:0000107
RGD
Ensembl
PMID:1672265 PMID:19052258 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
IEA
ISS
(PMID:1672265)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:1672265 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:18480058)
Ensembl
RGD
PMID:18480058 GO_REF:0000107 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15705806)
UniProt
Ensembl
RGD
PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3701833 (MGI:5464224|PMID:23133519), (MGI:5707553|PMID:26375174) RGD PMID:23133519 PMID:26375174 MGI:5464224 MGI:5707553 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267
JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20045483 RGD:4145470 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8187959 RGD:2292619 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Npsr1 neuropeptide S receptor 1 involved_in ISO
IBA
IEA
ISS
(PMID:16790440)
PMID:21873635
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16790440 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:10799761 RGD:9743926 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:22454520) RGD PMID:22454520 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Plcg1 phospholipase C, gamma 1 involved_in ISO
IEA
(PMID:22454520)
GO_REF:0000107
RGD
Ensembl
PMID:22454520 GO_REF:0000107 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:15641770) RGD PMID:15641770 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) RGD PMID:22338092 MGI:5487506 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Tex101 testis expressed 101 IDA RGD PMID:11809740 RGD:634491 NCBI chr 1:80,255,076...80,259,442
Ensembl chr 1:80,255,076...80,259,442
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IDA
IBA
PMID:2873512
PMID:21873635
UniProt
GO_Central
PMID:2873512 PMID:21873635 RGD:8554039, RGD:13792537 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Trdn triadin IMP RGD PMID:21811790 RGD:7327228 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19052258)
Ensembl
RGD
PMID:19052258 GO_REF:0000107 NCBI chr 8:96,263,322...96,314,197
Ensembl chr 8:96,263,329...96,314,276
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:7602097) RGD PMID:7602097 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IDA
ISO
IEA
PMID:12873381
(MGI:3603715|PMID:15379999)
GO_REF:0000107
RGD
Ensembl
PMID:15379999 PMID:12873381 GO_REF:0000107 MGI:3603715, RGD:6482800 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Htt huntingtin involved_in IEA
ISO
GO_REF:0000107
(PMID:12873381)
Ensembl
RGD
PMID:12873381 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in IMP PMID:17410128 ARUK-UCL PMID:17410128 RGD:13673830 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16223735) RGD PMID:16223735 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 involved_in IDA PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Calm1 calmodulin 1 involved_in IBA
ISO
PMID:21873635
(PMID:20226167)
RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 involved_in IBA
ISO
PMID:21873635
(PMID:20226167)
RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 involved_in ISO
IBA
(PMID:20226167)
PMID:21873635
RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO
IEA
(PMID:17023043)
GO_REF:0000107
RGD
Ensembl
PMID:17023043 GO_REF:0000107 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:11035031)
Ensembl
RGD
PMID:11035031 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Jph2 junctophilin 2 involved_in ISO (PMID:20095964) RGD PMID:20095964 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904
JBrowse link
G Trdn triadin involved_in ISO
IBA
(PMID:15041652), (PMID:15731460)
PMID:21873635
RGD PMID:15041652 PMID:15731460 PMID:21873635 RGD:13792537 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    cellular process 18252
      positive regulation of cellular process 6034
        positive regulation of calcium ion transport into cytosol 70
          positive regulation of release of sequestered calcium ion into cytosol 47
            positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
            positive regulation of ryanodine-sensitive calcium-release channel activity 9
Path 2
Term Annotations click to browse term
  biological_process 19391
    biological regulation 13476
      regulation of biological quality 4153
        homeostatic process 1991
          chemical homeostasis 1357
            ion homeostasis 869
              cellular ion homeostasis 738
                cellular cation homeostasis 722
                  cellular metal ion homeostasis 655
                    cellular calcium ion homeostasis 516
                      regulation of cytosolic calcium ion concentration 414
                        positive regulation of cytosolic calcium ion concentration 362
                          calcium ion transport into cytosol 177
                            calcium ion transmembrane import into cytosol 153
                              release of sequestered calcium ion into cytosol 127
                                regulation of release of sequestered calcium ion into cytosol 88
                                  positive regulation of release of sequestered calcium ion into cytosol 47
                                    positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
                                    positive regulation of ryanodine-sensitive calcium-release channel activity 9
paths to the root