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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051281 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: positive regulation of cytosolic release of sequestered calcium ion (Ca2+);   positive regulation of cytosolic release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytosol;   up regulation of release of sequestered calcium ion into cytosol;   upregulation of release of sequestered calcium ion into cytosol
 narrow_synonym: activation of release of sequestered calcium ion into cytosol;   stimulation of release of sequestered calcium ion into cytosol
 broad_synonym: positive regulation of calcium ion (Ca2+) mobilization;   positive regulation of calcium mobilization;   positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   positive regulation of cytoplasmic release of stored calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion (Ca2+);   positive regulation of release of sequestered calcium ion into cytoplasm;   positive regulation of release of stored calcium ion (Ca2+);   positive regulation of release of stored calcium ion (Ca2+) into cytoplasm


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positive regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:88319 (MGI:3839222|PMID:19228876) RGD PMID:19228876 MGI:3839222 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Aplnr apelin receptor involved_in ISO
ISS		 (PMID:25639753)
GO_REF:0000024		 RGD
UniProt		 PMID:25639753 GO_REF:0000024 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:3694443|PMID:15947791) RGD PMID:15947791 MGI:3694443 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdkrb1 bradykinin receptor B1 NOT IDA in nociceptive dorsal root ganglion neurons
in urinary bladder urothelium		 RGD PMID:15319421 PMID:15576455 RGD:1625754, RGD:1625040 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Capn3 calpain 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3811664|PMID:18676612)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18676612 GO_REF:0000024 GO_REF:0000107 MGI:3811664 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Casq1 calsequestrin 1 involved_in ISO
ISS		 (PMID:28895244)
GO_REF:0000024		 RGD
UniProt		 PMID:28895244 GO_REF:0000024 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within		 ISO (PMID:16672701), (PMID:9382888)
MGI:87859 (MGI:3839222|PMID:19228876)
(MGI:1100180|PMID:9382888)		 RGD PMID:9382888 PMID:16672701 PMID:19228876 MGI:1100180 MGI:3839222 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23990668)		 UniProt
RGD		 PMID:23990668 GO_REF:0000024 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 acts_upstream_of_or_within ISO (MGI:3618731|PMID:12777403) RGD PMID:12777403 MGI:3618731 NCBI chr 4:156,462,742...156,486,240
Ensembl chr 4:156,462,742...156,486,240 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA		 UniProtKB:P35411 (PMID:10415068), (PMID:10869418)
GO_REF:0000107		 RGD
Ensembl		 PMID:10415068 PMID:10869418 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
ISS		 (PMID:12782716)
GO_REF:0000024		 RGD
UniProt		 PMID:12782716 GO_REF:0000024 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12782716) RGD PMID:12782716 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12782716)		 UniProt
RGD		 PMID:12782716 GO_REF:0000024 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Dbi diazepam binding inhibitor IMP RGD PMID:9804683 RGD:2316286 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO (PMID:1282671), (PMID:7838121) RGD PMID:1282671 PMID:7838121 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:12628492 RGD:728499 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G F2 coagulation factor II involved_in ISO
IEA		 (PMID:1672265), (PMID:19052258)
GO_REF:0000107		 RGD
Ensembl		 PMID:1672265 PMID:19052258 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
ISS
IEA		 (PMID:1672265)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:1672265 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in ISO (PMID:18480058) RGD PMID:18480058 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15705806)		 UniProt
Ensembl
RGD		 PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3701833 (MGI:5464224|PMID:23133519), (MGI:5707553|PMID:26375174) RGD PMID:23133519 PMID:26375174 MGI:5464224 MGI:5707553 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20045483 RGD:4145470 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8187959 RGD:2292619 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Npsr1 neuropeptide S receptor 1 involved_in ISO
IBA
IEA
ISS		 (PMID:16790440)
PMID:21873635
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16790440 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:10799761 RGD:9743926 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:22454520) RGD PMID:22454520 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Plcg1 phospholipase C, gamma 1 involved_in ISO (PMID:22454520) RGD PMID:22454520 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:15641770) RGD PMID:15641770 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) RGD PMID:22338092 MGI:5487506 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IDA
IBA		 PMID:2873512
PMID:21873635		 UniProt
GO_Central		 PMID:2873512 PMID:21873635 RGD:8554039, RGD:13792537 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Trdn triadin IMP RGD PMID:21811790 RGD:7327228 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19052258)		 Ensembl
RGD		 PMID:19052258 GO_REF:0000107 NCBI chr 8:96,263,322...96,314,197
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:7602097) RGD PMID:7602097 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IDA
ISO
IEA		 PMID:12873381
(MGI:3603715|PMID:15379999)
GO_REF:0000107		 RGD
Ensembl		 PMID:15379999 PMID:12873381 GO_REF:0000107 MGI:3603715, RGD:6482800 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Htt huntingtin involved_in IEA
ISO		 GO_REF:0000107
(PMID:12873381)		 Ensembl
RGD		 PMID:12873381 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in IMP PMID:17410128 ARUK-UCL PMID:17410128 RGD:13673830 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16223735) RGD PMID:16223735 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 involved_in IDA PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Calm1 calmodulin 1 involved_in IBA
ISO		 PMID:21873635
(PMID:20226167)		 RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 involved_in IBA
ISO		 PMID:21873635
(PMID:20226167)		 RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 involved_in ISO
IBA		 (PMID:20226167)
PMID:21873635		 RGD PMID:20226167 PMID:21873635 RGD:13792537 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:17023043) RGD PMID:17023043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11035031)		 Ensembl
RGD		 PMID:11035031 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Jph2 junctophilin 2 involved_in ISO (PMID:20095964) RGD PMID:20095964 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904 		JBrowse link
G Trdn triadin involved_in ISO
IBA		 (PMID:15041652), (PMID:15731460)
PMID:21873635		 RGD PMID:15041652 PMID:15731460 PMID:21873635 RGD:13792537 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    negative regulation of biological process 5782
      negative regulation of cellular process 4451
        negative regulation of sequestering of calcium ion 141
          release of sequestered calcium ion into cytosol 140
            positive regulation of release of sequestered calcium ion into cytosol 46
              positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
              positive regulation of ryanodine-sensitive calcium-release channel activity 9
Path 2
Term Annotations click to browse term
  biological_process 19738
    homeostatic process 1918
      chemical homeostasis 1175
        monoatomic ion homeostasis 658
          intracellular monoatomic ion homeostasis 579
            intracellular monoatomic cation homeostasis 568
              intracellular calcium ion homeostasis 336
                sequestering of calcium ion 145
                  regulation of sequestering of calcium ion 143
                    negative regulation of sequestering of calcium ion 141
                      release of sequestered calcium ion into cytosol 140
                        regulation of release of sequestered calcium ion into cytosol 89
                          positive regulation of release of sequestered calcium ion into cytosol 46
                            positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
                            positive regulation of ryanodine-sensitive calcium-release channel activity 9
paths to the root