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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051280 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: down regulation of release of sequestered calcium ion into cytosol;   downregulation of release of sequestered calcium ion into cytosol;   negative regulation of cytosolic release of sequestered calcium ion (Ca2+);   negative regulation of cytosolic release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytosol
 narrow_synonym: inhibition of release of sequestered calcium ion into cytosol
 broad_synonym: negative regulation of calcium ion (Ca2+) mobilization;   negative regulation of calcium mobilization;   negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   negative regulation of cytoplasmic release of stored calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion into cytoplasm;   negative regulation of release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytoplasm



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negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcrl5 Fc receptor-like 5 acts_upstream_of_or_within ISO MGI:96055|MGI:96892 (MGI:5471851|PMID:23509253) RGD PMID:23509253 MGI:5471851 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:12084713 RGD:727385 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Prkce protein kinase C, epsilon involved_in IMP PMID:20383739 UniProt PMID:20383739 RGD:7206836 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IDA RGD PMID:12876066 RGD:731229 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IDA RGD PMID:12876066 RGD:731229 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Trdn triadin IMP RGD PMID:16176928 RGD:7327230 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
JBrowse link
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO
ISS
(PMID:26164367)
GO_REF:0000024
RGD
UniProt
PMID:26164367 GO_REF:0000024 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 involved_in ISO
ISS
(PMID:26164367)
GO_REF:0000024
RGD
UniProt
PMID:26164367 GO_REF:0000024 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 involved_in ISO
ISS
(PMID:26164367)
GO_REF:0000024
RGD
UniProt
PMID:26164367 GO_REF:0000024 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Casq2 calsequestrin 2 involved_in ISO
IMP
(PMID:16601229)
PMID:17569730
(PMID:15041652)
RGD PMID:15041652 PMID:16601229 PMID:17569730 RGD:2314601 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
JBrowse link
G Clic2 chloride intracellular channel 2 involved_in ISO (PMID:15147738), (PMID:15916532) RGD PMID:15147738 PMID:15916532 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:17023043), (PMID:22406107) RGD PMID:17023043 PMID:22406107 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO
IEA
(PMID:11035031)
GO_REF:0000107
RGD
Ensembl
PMID:11035031 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel acts_upstream_of_or_within ISO (MGI:3708075|PMID:17404231) RGD PMID:17404231 MGI:3708075 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Sri sorcin involved_in ISO (PMID:17699613) RGD PMID:17699613 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      positive regulation of cellular process 6029
        positive regulation of sequestering of calcium ion 19
          negative regulation of release of sequestered calcium ion into cytosol 17
            negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
            negative regulation of ryanodine-sensitive calcium-release channel activity 11
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological quality 4232
        homeostatic process 1900
          chemical homeostasis 1198
            ion homeostasis 663
              cellular ion homeostasis 542
                cellular cation homeostasis 524
                  cellular metal ion homeostasis 451
                    cellular calcium ion homeostasis 311
                      sequestering of calcium ion 137
                        regulation of sequestering of calcium ion 135
                          negative regulation of sequestering of calcium ion 133
                            release of sequestered calcium ion into cytosol 132
                              regulation of release of sequestered calcium ion into cytosol 90
                                negative regulation of release of sequestered calcium ion into cytosol 17
                                  negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
                                  negative regulation of ryanodine-sensitive calcium-release channel activity 11
paths to the root