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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051280 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: down regulation of release of sequestered calcium ion into cytosol;   downregulation of release of sequestered calcium ion into cytosol;   negative regulation of cytosolic release of sequestered calcium ion (Ca2+);   negative regulation of cytosolic release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytosol
 narrow_synonym: inhibition of release of sequestered calcium ion into cytosol
 broad_synonym: negative regulation of calcium ion (Ca2+) mobilization;   negative regulation of calcium mobilization;   negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   negative regulation of cytoplasmic release of stored calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion into cytoplasm;   negative regulation of release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytoplasm


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negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcrl5 Fc receptor-like 5 acts_upstream_of_or_within ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:12443530) RGD PMID:12443530 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:12084713 RGD:727385 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Prkce protein kinase C, epsilon involved_in IMP PMID:20383739 UniProt PMID:20383739 RGD:7206836 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IDA RGD PMID:12876066 RGD:731229 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IDA RGD PMID:12876066 RGD:731229 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Trdn triadin IMP RGD PMID:16176928 RGD:7327230 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595 		JBrowse link
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26164367)		 UniProt
RGD		 PMID:26164367 GO_REF:0000024 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26164367)		 UniProt
RGD		 PMID:26164367 GO_REF:0000024 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26164367)		 UniProt
RGD		 PMID:26164367 GO_REF:0000024 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Casq2 calsequestrin 2 involved_in IMP
ISO		 PMID:17569730
(PMID:16601229)
(PMID:15041652)		 RGD PMID:15041652 PMID:16601229 PMID:17569730 RGD:2314601 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267 		JBrowse link
G Clic2 chloride intracellular channel 2 involved_in ISO (PMID:15147738), (PMID:15916532) RGD PMID:15147738 PMID:15916532 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:17023043), (PMID:22406107) RGD PMID:17023043 PMID:22406107 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) RGD PMID:11035031 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel acts_upstream_of_or_within ISO (PMID:17404231) RGD PMID:17404231 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Sri sorcin involved_in ISO (PMID:17699613) RGD PMID:17699613 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      positive regulation of cellular process 6417
        positive regulation of sequestering of calcium ion 18
          negative regulation of release of sequestered calcium ion into cytosol 16
            negative regulation of ryanodine-sensitive calcium-release channel activity 9
Path 2
Term Annotations click to browse term
  biological_process 20537
    homeostatic process 2014
      chemical homeostasis 1225
        monoatomic ion homeostasis 680
          intracellular monoatomic ion homeostasis 592
            intracellular monoatomic cation homeostasis 581
              intracellular calcium ion homeostasis 340
                sequestering of calcium ion 140
                  regulation of sequestering of calcium ion 138
                    negative regulation of sequestering of calcium ion 136
                      release of sequestered calcium ion into cytosol 135
                        regulation of release of sequestered calcium ion into cytosol 90
                          negative regulation of release of sequestered calcium ion into cytosol 16
                            negative regulation of ryanodine-sensitive calcium-release channel activity 9
paths to the root