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ONTOLOGY REPORT - ANNOTATIONS

Term:protein depolymerization
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Accession:GO:0051261 term browser browse the term
Definition:The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
Synonyms:exact_synonym: protein polymer breakdown;   protein polymer catabolic process;   protein polymer catabolism;   protein polymer degradation

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protein depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:18687924) UniProt PMID:18687924 NCBI chrNW_004955402:47,154,350...47,183,979
Ensembl chrNW_004955402:47,154,007...47,184,021 		JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:19666531)
(PMID:23325791) 		UniProt PMID:19666531 PMID:23325791 NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361 		JBrowse link
G Myh9 myosin heavy chain 9 NOT|involved_in ISO (PMID:23325791) UniProt PMID:23325791 NCBI chrNW_004955413:22,881,759...22,972,182
Ensembl chrNW_004955413:22,881,045...22,972,450 		JBrowse link
G Scin scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chrNW_004955410:16,286,131...16,358,286
Ensembl chrNW_004955410:16,285,217...16,358,280 		JBrowse link
G Tpm1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chrNW_004955450:12,197,241...12,223,372
Ensembl chrNW_004955450:12,194,755...12,224,011 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) UniProt PMID:16921170 PMID:17182858 PMID:19808673 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 ISO RGD PMID:18678705 RGD:2313131 NCBI chrNW_004955547:547,770...555,764
Ensembl chrNW_004955547:547,064...555,958 		JBrowse link
G Cfl1 cofilin 1 involved_in ISO (PMID:11812157)
(PMID:11809832) 		UniProt PMID:11809832 PMID:11812157 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
G Cfl2 cofilin 2 involved_in
acts_upstream_of_or_within 		ISO (PMID:19752190)
(PMID:11809832)
(PMID:24840128) 		UniProt
MGI		 PMID:11809832 PMID:19752190 PMID:24840128 NCBI chrNW_004955409:26,247,050...26,250,082
Ensembl chrNW_004955409:26,246,369...26,250,082 		JBrowse link
G Dstn destrin, actin depolymerizing factor involved_in ISO (PMID:11812157)
(PMID:11809832) 		UniProt PMID:11809832 PMID:11812157 NCBI chrNW_004955415:26,567,457...26,598,978
Ensembl chrNW_004955415:26,569,264...26,600,862 		JBrowse link
G Gsn gelsolin involved_in ISO (PMID:30568254) BHF-UCL
RGD		 PMID:11861757 PMID:30568254 RGD:1303950 NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361 		JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 involved_in ISO (PMID:21864500), (PMID:28230050), (PMID:33393173)
(PMID:23911929) 		UniProt PMID:21864500 PMID:23911929 PMID:28230050 PMID:33393173 NCBI chrNW_004955411:34,484,536...34,495,154
Ensembl chrNW_004955411:34,484,653...34,493,877 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 involved_in ISO (PMID:24440334), (PMID:29343822)
(PMID:23911929) 		UniProt PMID:23911929 PMID:24440334 PMID:29343822 NCBI chrNW_004955414:27,600,823...27,804,232
Ensembl chrNW_004955414:27,612,253...27,724,297 		JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 involved_in ISO (PMID:24440334) UniProt PMID:24440334 NCBI chrNW_004955454:5,820,291...5,983,262
Ensembl chrNW_004955454:5,820,299...5,983,101 		JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chrNW_004955451:11,516,548...11,530,263
Ensembl chrNW_004955451:11,516,548...11,530,830 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:11500485) UniProt PMID:11500485 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
actin filament fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 involved_in ISO (PMID:11809832) UniProt PMID:11809832 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
G Cfl2 cofilin 2 involved_in ISO (PMID:11809832) UniProt PMID:11809832 NCBI chrNW_004955409:26,247,050...26,250,082
Ensembl chrNW_004955409:26,246,369...26,250,082 		JBrowse link
G Dstn destrin, actin depolymerizing factor involved_in ISO (PMID:11809832) UniProt PMID:11809832 NCBI chrNW_004955415:26,567,457...26,598,978
Ensembl chrNW_004955415:26,569,264...26,600,862 		JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (PMID:25915128) UniProt PMID:25915128 NCBI chrNW_004955549:2,640,193...2,674,818
Ensembl chrNW_004955549:2,640,195...2,673,969 		JBrowse link
actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) UniProt PMID:25433700 NCBI chrNW_004955492:3,483,704...3,554,831
Ensembl chrNW_004955492:3,483,511...3,555,190 		JBrowse link
axonemal microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (PMID:23168168) UniProt PMID:23168168 NCBI chrNW_004955553:1,219,462...1,247,161
Ensembl chrNW_004955553:1,218,659...1,248,879 		JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955514:1,784,302...1,812,845
Ensembl chrNW_004955514:1,783,814...1,815,917 		JBrowse link
G Add2 adducin 2 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955424:14,411,279...14,517,813
Ensembl chrNW_004955424:14,411,124...14,517,813 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within ISO (PMID:17656356) MGI PMID:17656356 NCBI chrNW_004955435:16,048,213...16,087,814
Ensembl chrNW_004955435:16,048,213...16,087,814 		JBrowse link
G Dbnl drebrin like NOT|acts_upstream_of_or_within ISO (PMID:10637315) MGI PMID:10637315 NCBI chrNW_004955456:7,912,827...7,924,373
Ensembl chrNW_004955456:7,912,827...7,924,787 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in ISO (PMID:23314863)
(PMID:15558031), (PMID:20532239) 		UniProt PMID:15558031 PMID:20532239 PMID:23314863 NCBI chrNW_004955413:12,267,701...12,386,088
Ensembl chrNW_004955413:12,266,371...12,386,088 		JBrowse link
G Rdx radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chrNW_004955412:12,100,436...12,184,444
Ensembl chrNW_004955412:12,100,359...12,172,545 		JBrowse link
G Twf1 twinfilin actin binding protein 1 involved_in ISO (PMID:18837697) BHF-UCL PMID:18837697 NCBI chrNW_004955500:3,050,028...3,070,799 JBrowse link
G Twf2 twinfilin actin binding protein 2 involved_in ISO (PMID:18837697) BHF-UCL PMID:18837697 NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) UniProt PMID:16054028 NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520 		JBrowse link
clathrin coat disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 acts_upstream_of_or_within ISO (PMID:20160091) MGI PMID:20160091 NCBI chrNW_004955423:25,269,459...25,382,664
Ensembl chrNW_004955423:25,269,466...25,377,641 		JBrowse link
G Gak cyclin G associated kinase involved_in
acts_upstream_of_or_within 		ISO (PMID:16155256)
(PMID:20160091) 		ParkinsonsUK-UCL
MGI		 PMID:16155256 PMID:20160091 NCBI chrNW_004955514:391,305...434,198
Ensembl chrNW_004955514:387,179...434,077 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in
acts_upstream_of_or_within 		ISO (PMID:8524399)
(PMID:20160091) 		RGD
UniProt
MGI		 PMID:8363588 PMID:8524399 PMID:20160091 RGD:10059376 RGD:401901214 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of ISO (PMID:16525027) MGI PMID:16525027 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 ISO RGD PMID:20858895 RGD:7242937 NCBI chrNW_004955555:941,539...961,407 JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of ISO (PMID:25099998) MGI PMID:25099998 NCBI chrNW_004955442:317,334...442,514
Ensembl chrNW_004955442:314,486...442,088 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO RGD PMID:20858895 RGD:7242937 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of ISO (PMID:17113391) MGI PMID:17113391 NCBI chrNW_004955421:767,648...957,160
Ensembl chrNW_004955421:767,210...897,457 		JBrowse link
G Htt huntingtin ISO RGD PMID:20858895 RGD:7242937 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889 		JBrowse link
G Kif14 kinesin family member 14 NOT|involved_in ISO (PMID:24949858) UniProt PMID:24949858 NCBI chrNW_004955406:36,732,135...36,791,756
Ensembl chrNW_004955406:36,737,484...36,791,756 		JBrowse link
G Kif18a kinesin family member 18A involved_in ISO (PMID:17346968) UniProt PMID:17346968 NCBI chrNW_004955476:7,058,682...7,117,496
Ensembl chrNW_004955476:7,058,573...7,109,610 		JBrowse link
G Kif18b kinesin family member 18B involved_in ISO (PMID:21820309) UniProt PMID:21820309 NCBI chrNW_004955451:17,707,150...17,722,376
Ensembl chrNW_004955451:17,706,661...17,722,433 		JBrowse link
G Kif24 kinesin family member 24 involved_in ISO (PMID:21620453) UniProt PMID:21620453 NCBI chrNW_004955472:1,774,850...1,868,525
Ensembl chrNW_004955472:1,792,520...1,860,056 		JBrowse link
G Kif2b kinesin family member 2B involved_in ISO (PMID:19060894) UniProt PMID:19060894 NCBI chrNW_004955451:8,528,405...8,530,661 JBrowse link
G Kif2c kinesin family member 2C involved_in ISO (PMID:21820309)
(PMID:19060894) 		UniProt PMID:19060894 PMID:21820309 NCBI chrNW_004955464:13,453,637...13,475,447
Ensembl chrNW_004955464:13,453,217...13,475,322 		JBrowse link
G Nckap5l NCK associated protein 5 like involved_in ISO (PMID:26485573) UniProt PMID:26485573 NCBI chrNW_004955547:381,338...416,658
Ensembl chrNW_004955547:379,440...417,284 		JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:20858895 RGD:7242937 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO RGD PMID:16982696 RGD:1642763 NCBI chrNW_004955439:2,399,992...2,406,587
Ensembl chrNW_004955439:2,290,035...2,406,587 		JBrowse link
G Stmn1 stathmin 1 involved_in
acts_upstream_of_or_within 		ISO (PMID:10675326)
(PMID:9880330) 		CAFA
MGI		 PMID:9880330 PMID:10675326 NCBI chrNW_004955452:5,387,696...5,393,337
Ensembl chrNW_004955452:5,388,150...5,391,518 		JBrowse link
mitotic spindle microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccsap centriole, cilia and spindle associated protein involved_in ISO (PMID:26562023) UniProt PMID:26562023 NCBI chrNW_004955492:8,685,667...8,700,306 JBrowse link
negative regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO (PMID:12566430) UniProt PMID:12566430 NCBI chrNW_004955547:730,152...827,644
Ensembl chrNW_004955547:730,073...827,783 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (PMID:30568254) BHF-UCL PMID:30568254 NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024 		JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 involved_in ISO (PMID:22832517) UniProt PMID:22832517 NCBI chrNW_004955441:10,818,982...10,921,224
Ensembl chrNW_004955441:10,825,499...10,919,901 		JBrowse link
G Shroom2 shroom family member 2 acts_upstream_of_or_within ISO (PMID:17666436) MGI PMID:17666436 NCBI chrNW_004955499:8,031,961...8,103,307
Ensembl chrNW_004955499:8,031,615...8,100,952 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:21703590) MGI PMID:21703590 NCBI chrNW_004955455:7,739,105...7,879,489
Ensembl chrNW_004955455:7,739,463...7,882,427 		JBrowse link
G Swap70 switching B cell complex subunit SWAP70 involved_in ISO (PMID:23921380) CACAO PMID:23921380 NCBI chrNW_004955414:25,385,648...25,444,743
Ensembl chrNW_004955414:25,385,007...25,444,913 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) UniProt PMID:16054028 NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chrNW_004955484:9,025,409...9,037,942
Ensembl chrNW_004955484:9,025,460...9,037,580 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chrNW_004955447:14,650,035...14,672,593 JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chrNW_004955546:2,718,758...2,764,277 JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within 		ISO (PMID:11166179)
(PMID:16525027)
(PMID:17192415) 		UniProt
MGI		 PMID:11166179 PMID:16525027 PMID:17192415 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:11912491) UniProt PMID:11912491 NCBI chrNW_004955545:2,149,107...2,192,986
Ensembl chrNW_004955545:2,149,107...2,197,153 		JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) CACAO PMID:22100762 NCBI chrNW_004955517:1,897,050...1,980,428
Ensembl chrNW_004955517:1,892,757...1,980,524 		JBrowse link
G Bbof1 basal body orientation factor 1 acts_upstream_of_or_within ISO (PMID:37494937) MGI PMID:37494937 NCBI chrNW_004955523:1,363,246...1,405,022 JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of_or_within ISO (PMID:25099998) MGI PMID:25099998 NCBI chrNW_004955442:317,334...442,514
Ensembl chrNW_004955442:314,486...442,088 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C acts_upstream_of_or_within ISO (PMID:33929515) MGI PMID:33929515 NCBI chrNW_004955438:13,585,469...13,708,170 JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO (PMID:21215777) UniProt PMID:21215777 NCBI chrNW_004955416:15,102,632...15,106,372
Ensembl chrNW_004955416:15,102,632...15,106,372 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 acts_upstream_of_or_within ISO (PMID:16061649) MGI PMID:16061649 NCBI chrNW_004955431:5,416,596...5,429,465
Ensembl chrNW_004955431:5,418,103...5,427,463 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within 		ISO (PMID:15631994)
(PMID:11290329)
(PMID:16866869) 		UniProt
MGI		 PMID:11290329 PMID:15631994 PMID:16866869 NCBI chrNW_004955459:8,382,671...8,628,048
Ensembl chrNW_004955459:8,408,160...8,629,344 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within ISO (PMID:11290329)
(PMID:17113391) 		RGD
MGI		 PMID:11290329 PMID:17113391 RGD:68300 NCBI chrNW_004955421:767,648...957,160
Ensembl chrNW_004955421:767,210...897,457 		JBrowse link
G Diaph3 diaphanous related formin 3 acts_upstream_of_or_within ISO (PMID:18458159) MGI PMID:18458159 NCBI chrNW_004955404:44,653,308...45,106,943
Ensembl chrNW_004955404:44,653,501...45,105,966 		JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) MGI PMID:17196341 NCBI chrNW_004955441:9,633,906...9,715,866
Ensembl chrNW_004955441:9,640,899...9,713,596 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (PMID:22726441) UniProt PMID:22726441 NCBI chrNW_004955489:6,122,707...6,621,624
Ensembl chrNW_004955489:6,123,633...6,621,692 		JBrowse link
G Gas2l1 growth arrest specific 2 like 1 involved_in ISO (PMID:12584248) UniProt PMID:12584248 NCBI chrNW_004955455:3,613,092...3,618,476
Ensembl chrNW_004955455:3,613,092...3,621,306 		JBrowse link
G Gas2l2 growth arrest specific 2 like 2 involved_in ISO (PMID:12584248) UniProt PMID:12584248 NCBI chrNW_004955481:10,190,738...10,202,298
Ensembl chrNW_004955481:10,193,077...10,200,959 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (PMID:12486003) MGI PMID:12486003 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071 		JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISO (PMID:19237540) UniProt PMID:19237540 NCBI chrNW_004955416:13,501,132...13,561,095
Ensembl chrNW_004955416:13,538,387...13,561,095 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) UniProt PMID:10751153 NCBI chrNW_004955433:15,345,246...15,365,986
Ensembl chrNW_004955433:15,345,246...15,366,039 		JBrowse link
G Map1a microtubule associated protein 1A ISO RGD PMID:11896150 RGD:71122 NCBI chrNW_004955416:10,052,964...10,073,318
Ensembl chrNW_004955416:10,053,010...10,071,421 		JBrowse link
G Map1b microtubule associated protein 1B ISO RGD PMID:11896150 RGD:71122 NCBI chrNW_004955575:914,607...1,020,971
Ensembl chrNW_004955575:913,723...1,021,028 		JBrowse link
G Map2 microtubule associated protein 2 involved_in ISO PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024 		JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO (PMID:15070402) MGI PMID:15070402 NCBI chrNW_004955544:2,379,766...2,718,282
Ensembl chrNW_004955544:2,484,854...2,719,112 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 acts_upstream_of_or_within ISO (PMID:15070402) MGI PMID:15070402 NCBI chrNW_004955566:287,578...289,803
Ensembl chrNW_004955566:287,578...289,803 		JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) UniProt PMID:25678558 NCBI chrNW_004955405:16,428,643...17,213,253
Ensembl chrNW_004955405:16,869,441...17,213,325 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:21703590) MGI PMID:21703590 NCBI chrNW_004955455:7,739,105...7,879,489
Ensembl chrNW_004955455:7,739,463...7,882,427 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (PMID:16206169) UniProt PMID:16206169 NCBI chrNW_004955415:14,620,593...14,626,049
Ensembl chrNW_004955415:14,620,593...14,626,049 		JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) UniProt PMID:18452648 NCBI chrNW_004955444:1,585,042...1,646,812
Ensembl chrNW_004955444:1,584,560...1,646,812 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:12639963) ARUK-UCL PMID:12639963 NCBI chrNW_004955481:3,698,686...3,836,209
Ensembl chrNW_004955481:3,705,202...3,772,116 		JBrowse link
G Tpx2 TPX2 microtubule nucleation factor involved_in ISO (PMID:26414402) CACAO PMID:26414402 NCBI chrNW_004955422:29,170,695...29,233,924
Ensembl chrNW_004955422:29,171,329...29,232,891 		JBrowse link
G Trim54 tripartite motif containing 54 acts_upstream_of_or_within ISO (PMID:10953002) MGI PMID:10953002 NCBI chrNW_004955469:9,258,946...9,277,275
Ensembl chrNW_004955469:9,258,946...9,277,275 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) ARUK-UCL PMID:26323690 NCBI chrNW_004955416:9,412,297...9,518,561
Ensembl chrNW_004955416:9,412,297...9,559,655 		JBrowse link
G Wdr47 WD repeat domain 47 acts_upstream_of_or_within ISO (PMID:29078390) MGI PMID:29078390 NCBI chrNW_004955435:12,414,964...12,479,883
Ensembl chrNW_004955435:12,414,600...12,466,040 		JBrowse link
plus-end specific microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (PMID:23168168) UniProt PMID:23168168 NCBI chrNW_004955553:1,219,462...1,247,161
Ensembl chrNW_004955553:1,218,659...1,248,879 		JBrowse link
positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 acts_upstream_of_or_within
involved_in 		ISO (PMID:15548599)
(PMID:23921380) 		MGI
CACAO		 PMID:15548599 PMID:23921380 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
G Cfl2 cofilin 2 involved_in ISO (PMID:17160903) UniProt PMID:17160903 NCBI chrNW_004955409:26,247,050...26,250,082
Ensembl chrNW_004955409:26,246,369...26,250,082 		JBrowse link
G Dstn destrin, actin depolymerizing factor acts_upstream_of_or_within ISO (PMID:15548599) MGI PMID:15548599 NCBI chrNW_004955415:26,567,457...26,598,978
Ensembl chrNW_004955415:26,569,264...26,600,862 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17500066) UniProt PMID:17500066 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO (PMID:15580268) UniProt PMID:15580268 NCBI chrNW_004955413:24,055,900...24,063,902 JBrowse link
G Plek pleckstrin involved_in ISO (PMID:10497244)
(PMID:19190246) 		BHF-UCL PMID:10497244 PMID:19190246 NCBI chrNW_004955424:16,494,052...16,524,790
Ensembl chrNW_004955424:16,493,960...16,524,998 		JBrowse link
G Sema5a semaphorin 5A involved_in ISO (PMID:19850054) UniProt PMID:19850054 NCBI chrNW_004955504:6,343,747...6,691,945
Ensembl chrNW_004955504:6,350,866...6,762,104 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (PMID:24840128) MGI PMID:24840128 NCBI chrNW_004955549:2,640,193...2,674,818
Ensembl chrNW_004955549:2,640,195...2,673,969 		JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041 		JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
positive regulation of intermediate filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nes nestin involved_in ISO PMID:12686602 UniProt PMID:12686602 RGD:633505 NCBI chrNW_004955545:2,748,132...2,756,595
Ensembl chrNW_004955545:2,748,078...2,756,301 		JBrowse link
positive regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO (PMID:31804178) UniProt PMID:31804178 NCBI chrNW_004955467:8,715,387...8,720,889
Ensembl chrNW_004955467:8,715,136...8,723,932 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:18442977 RGD:7241017 NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) UniProt PMID:10751153 NCBI chrNW_004955433:15,345,246...15,365,986
Ensembl chrNW_004955433:15,345,246...15,366,039 		JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) UniProt PMID:18452648 NCBI chrNW_004955444:1,585,042...1,646,812
Ensembl chrNW_004955444:1,584,560...1,646,812 		JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chrNW_004955455:8,744,865...8,781,644
Ensembl chrNW_004955455:8,744,176...8,783,741 		JBrowse link
regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3bp1 SH3 domain binding protein 1 involved_in ISO (PMID:24841563) UniProt PMID:24841563 NCBI chrNW_004955413:24,042,875...24,054,826
Ensembl chrNW_004955413:24,042,875...24,055,041 		JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (PMID:15629458) UniProt PMID:15629458 NCBI chrNW_004955549:2,640,193...2,674,818
Ensembl chrNW_004955549:2,640,195...2,673,969 		JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO (PMID:16895918) UniProt PMID:16895918 NCBI chrNW_004955494:6,805,518...6,844,454
Ensembl chrNW_004955494:6,805,262...6,845,394 		JBrowse link
regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif21a kinesin family member 21A involved_in ISO (PMID:24120883) UniProt PMID:24120883 NCBI chrNW_004955505:933,254...1,000,039
Ensembl chrNW_004955505:933,270...998,853 		JBrowse link
regulation of protein depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate beta-hydroxylase involved_in ISO (PMID:22123818) BHF-UCL PMID:22123818 NCBI chrNW_004955444:17,116,060...17,320,966
Ensembl chrNW_004955444:17,121,559...17,318,295 		JBrowse link
synaptic vesicle uncoating term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 involved_in ISO (PMID:20160091) SynGO PMID:20160091 NCBI chrNW_004955423:25,269,459...25,382,664
Ensembl chrNW_004955423:25,269,466...25,377,641 		JBrowse link
G Synj1 synaptojanin 1 acts_upstream_of_or_within
involved_in 		ISO (PMID:12481038)
(PMID:10535736) 		MGI
SynGO		 PMID:10535736 PMID:12481038 NCBI chrNW_004955407:32,094,076...32,175,676
Ensembl chrNW_004955407:32,093,479...32,175,795 		JBrowse link
vesicle uncoating term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:15075231) UniProt PMID:15075231 NCBI chrNW_004955484:7,368,938...7,375,964
Ensembl chrNW_004955484:7,368,938...7,375,969 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12628
    cellular process 12059
      cellular component organization or biogenesis 5431
        cellular component organization 5301
          protein-containing complex organization 1342
            protein-containing complex disassembly 216
              protein depolymerization 98
                actin filament depolymerization + 40
                free ubiquitin chain depolymerization 0
                intermediate filament depolymerization + 1
                lamin depolymerization 0
                microtubule depolymerization + 51
                negative regulation of protein depolymerization + 57
                positive regulation of protein depolymerization + 20
                regulation of protein depolymerization + 72
                vesicle uncoating + 5
paths to the root