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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein metabolic process
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Accession:GO:0051247 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
Synonyms:exact_synonym: positive regulation of protein metabolism;   up regulation of protein metabolic process;   upregulation of protein metabolic process
 narrow_synonym: activation of protein metabolic process;   stimulation of protein metabolic process

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positive regulation of protein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IDA		 (PMID:11404397) RGD PMID:11404397, PMID:11404397, PMID:11404397 RGD:12790656, RGD:12790656 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO UniProtKB:P05067 (MGI:4437154|PMID:20164328) RGD PMID:20164328 MGI:4437154 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Gba glucosylceramidase beta involved_in ISO UniProtKB:P37840 (PMID:26392287) RGD PMID:26392287 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601 		JBrowse link
G Klf2 Kruppel-like factor 2 involved_in ISO UniProtKB:Q62862 (PMID:20551324) RGD PMID:20551324 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037 		JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO UniProtKB:Q62862 (PMID:20551324) RGD PMID:20551324 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324, PMID:20551324 RGD:8553940, RGD:8553940 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO UniProtKB:Q62862 (PMID:20551324) RGD PMID:20551324 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO
IEA		 (PMID:22027397)
GO_REF:0000107		 RGD
Ensembl		 PMID:22027397 GO_REF:0000107 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mtpn myotrophin involved_in IDA PMID:18693253 UniProt PMID:18693253, PMID:18693253 RGD:8553542, RGD:8553542 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:17947299) RGD PMID:17947299 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966 		JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 5:22,577,680...22,799,333
Ensembl chr 5:22,577,675...22,799,349 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IBA		 (PMID:18387192)
PMID:21873635		 RGD PMID:18387192, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b involved_in ISO (PMID:12595532) RGD PMID:12595532 NCBI chr15:34,439,844...34,444,244
Ensembl chr15:34,439,876...34,444,244 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 involved_in ISO
IBA		 (PMID:18387192)
PMID:21873635		 RGD PMID:18387192, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:31,278,746...31,419,235
Ensembl chr10:31,278,746...31,419,235 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Lgmn legumain involved_in IEA
ISO		 GO_REF:0000107
(PMID:18374643), (PMID:9821970)		 Ensembl
RGD		 PMID:9821970 PMID:18374643 GO_REF:0000107 NCBI chr 6:126,282,246...126,308,207
Ensembl chr 6:126,282,233...126,320,726 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:10349840 RGD:9835366 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:5491128|PMID:23302887) RGD PMID:23302887 MGI:5491128 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735 		JBrowse link
G Tbc1d10a TBC1 domain family, member 10a involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr14:84,417,320...84,445,034
Ensembl chr14:84,417,320...84,445,034 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067042.3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 9:27,554,751...27,556,861 JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20628055) RGD PMID:20628055 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 involved_in ISO
ISS		 (PMID:17094969)
GO_REF:0000024		 RGD
UniProt		 PMID:17094969 GO_REF:0000024 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B involved_in IEA
ISO		 GO_REF:0000107
(PMID:20015864)		 Ensembl
RGD		 PMID:20015864 GO_REF:0000107 NCBI chr 5:62,070,709...62,094,633
Ensembl chr 5:62,071,346...62,094,633 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:21827945)
MGI:1349414|MGI:1857868|MGI:1928692 (MGI:3575207|PMID:15776018), (MGI:3577148|PMID:15703386)		 RGD PMID:15703386 PMID:15776018 PMID:21827945 MGI:3575207 MGI:3577148 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in ISO
IEA		 (PMID:16725111)
GO_REF:0000107		 RGD
Ensembl		 PMID:16725111 GO_REF:0000107 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453294|PMID:19915011)		 UniProt
RGD		 PMID:19915011 GO_REF:0000024 MGI:4453294 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:2159364|MGI:99702 (MGI:2667259|PMID:12847083), (MGI:3575207|PMID:15776018), (MGI:3662939|PMID:16893972) RGD PMID:12847083 PMID:15776018 PMID:16893972 MGI:2667259 MGI:3575207 MGI:3662939 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:5009404|PMID:16735463)
MGI:1097161|MGI:1857429|MGI:2158306 (MGI:2667259|PMID:12847083), (MGI:3041326|PMID:14561915), (MGI:3575207|PMID:15776018), (MGI:3692043|PMID:14502238)
(PMID:11350920), (PMID:11912183)
MGI:1097161|MGI:1857429|MGI:2158306 (MGI:2667259|PMID:12847083), (MGI:3041326|PMID:14561915), (MGI:3575207|PMID:15776018), (MGI:3692043|PMID:14502238), (MGI:5009404|PMID:16735463)		 UniProt
RGD		 PMID:11350920 PMID:11912183 PMID:12847083 PMID:14502238 PMID:14561915 PMID:15776018 PMID:16735463 GO_REF:0000024 MGI:2667259 MGI:3041326 MGI:3575207 MGI:3692043 MGI:5009404 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11463392), (PMID:17024184)		 RGD PMID:11463392 PMID:17024184, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2l11 BCL2 like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2158671 (MGI:2183141|PMID:12011074)
PMID:21873635		 RGD PMID:12011074, PMID:21873635, PMID:21873635 MGI:2183141, RGD:13792537, RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
ISS		 (PMID:20673843)
GO_REF:0000024		 RGD
UniProt		 PMID:20673843 GO_REF:0000024 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504 		JBrowse link
G Casp1 caspase 1 NOT
NOT|involved_in		 IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Casp12 caspase 12 NOT
NOT|involved_in		 IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160 		JBrowse link
G Casp2 caspase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239 		JBrowse link
G Casp4 caspase 4 NOT|involved_in TAS
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11684090, PMID:21873635, PMID:21873635 RGD:632459, RGD:13792537, RGD:13792537 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652 		JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2183141|PMID:12011074)
PMID:21873635		 RGD PMID:12011074, PMID:21873635, PMID:21873635 MGI:2183141, RGD:13792537, RGD:13792537 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:17245429)
(MGI:1347587|PMID:10235259)
PMID:21873635		 RGD PMID:10235259 PMID:17245429, PMID:21873635, PMID:21873635 MGI:1347587, RGD:13792537, RGD:13792537 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668 		JBrowse link
G Casp9 caspase 9 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2158755 (MGI:3575207|PMID:15776018)
PMID:21873635		 RGD PMID:15776018, PMID:21873635, PMID:21873635 MGI:3575207, RGD:13792537, RGD:13792537 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain involved_in ISO (PMID:10766752) RGD PMID:10766752 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1889507 (MGI:3603971|PMID:16183742)
PMID:21873635		 RGD PMID:16183742, PMID:21873635, PMID:21873635 MGI:3603971, RGD:13792537, RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588 		JBrowse link
G Ctsh cathepsin H involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287 		JBrowse link
G Dap death-associated protein involved_in ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein acts_upstream_of_or_within ISO (MGI:2183141|PMID:12011074), (MGI:3587135|PMID:16085184) RGD PMID:12011074 PMID:16085184 MGI:2183141 MGI:3587135 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:17888903)		 Ensembl
RGD		 PMID:17888903 GO_REF:0000107 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:10411904) RGD PMID:10411904 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:20978507)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20978507 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:1858648|PMID:10882126) RGD PMID:10882126 MGI:1858648 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
IEA
ISS		 (PMID:10692450)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:10692450 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in ISO
IEA		 (PMID:17898544)
GO_REF:0000107		 RGD
Ensembl		 PMID:17898544 GO_REF:0000107 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISO
ISS		 (PMID:15082785)
GO_REF:0000024		 RGD
UniProt		 PMID:15082785 GO_REF:0000024 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253 		JBrowse link
G Faslg Fas ligand involved_in ISO UniProtKB:P18406 (PMID:18293083), (PMID:19364818) RGD PMID:18293083 PMID:19364818 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO
IBA		 (PMID:11788820)
PMID:21873635		 RGD PMID:11788820, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IBA		 (PMID:19255499)
PMID:21873635		 RGD PMID:19255499, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:38,024,517...38,053,184
Ensembl chr12:38,024,519...38,053,085 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:17823127) RGD PMID:17823127 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Ift57 intraflagellar transport 57 involved_in ISO (PMID:11788820) RGD PMID:11788820 NCBI chr11:53,664,638...53,731,779
Ensembl chr11:53,664,638...53,731,779 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:5009182 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Khdc1 KH domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:27,546,069...27,547,769
Ensembl chr 9:27,546,528...27,547,473 		JBrowse link
G Khdc1b KH domain containing 1B acts_upstream_of_or_within ISO (MGI:2683352|PMID:14657025) RGD PMID:14657025 MGI:2683352 NCBI chr 9:27,554,436...27,556,770 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO
IEA		 (PMID:28464033)
GO_REF:0000107		 RGD
Ensembl		 PMID:28464033 GO_REF:0000107 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 (PMID:16116473)
GO_REF:0000107		 RGD
Ensembl		 PMID:16116473 GO_REF:0000107 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983 		JBrowse link
G LOC100911519 p53-induced protein with a death domain-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:213,976,399...213,988,807
Ensembl chr 1:214,419,240...214,423,881
Ensembl chr 1:214,419,240...214,423,881 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355 		JBrowse link
G Mtch1 mitochondrial carrier 1 involved_in ISO (PMID:12377771) RGD PMID:12377771 NCBI chr20:6,937,341...6,961,165
Ensembl chr20:6,937,347...6,961,162 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:2677658 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Ngf nerve growth factor involved_in ISO UniProtKB:P08138 (PMID:11927634) RGD PMID:11927634 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:26268439)		 Ensembl
RGD		 PMID:26268439 GO_REF:0000107 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17486276), (PMID:19266349)		 UniProt
RGD		 PMID:17486276 PMID:19266349 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO
IBA		 (PMID:15212762)
PMID:21873635		 RGD PMID:15212762, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 acts_upstream_of_or_within ISO MGI:3686871 (MGI:3697006|PMID:17008311) RGD PMID:17008311 MGI:3697006 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO (PMID:10329646) RGD PMID:10329646 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325 		JBrowse link
G Pdcd2 programmed cell death 2 involved_in ISO (PMID:20605493) RGD PMID:20605493 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458 		JBrowse link
G Pdcd6 programmed cell death 6 acts_upstream_of_or_within ISO (MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:2684521 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849 		JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:17159900)
MGI:1336168 (MGI:3603971|PMID:16183742)
PMID:21873635		 RGD PMID:16183742 PMID:17159900, PMID:21873635, PMID:21873635 MGI:3603971, RGD:13792537, RGD:13792537 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (MGI:5009174|PMID:14699081) RGD PMID:14699081 MGI:5009174 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:1306978|PMID:9806545) RGD PMID:9806545 MGI:1306978 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO MGI:3686870 (MGI:3697006|PMID:17008311) RGD PMID:17008311 MGI:3697006 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372 		JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) RGD PMID:10082581 MGI:1333612 NCBI chr 8:104,326,719...104,336,098
Ensembl chr 8:104,326,719...104,335,729 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18566128)		 Ensembl
RGD		 PMID:18566128 GO_REF:0000107 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:17057733) RGD PMID:17057733 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090 		JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISO
ISS		 (PMID:19935772)
GO_REF:0000024		 RGD
UniProt		 PMID:19935772 GO_REF:0000024 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354 		JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:19935772)		 Ensembl
UniProt
RGD		 PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276 		JBrowse link
G Senp1 SUMO specific peptidase 1 involved_in ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in ISO (PMID:18082289) RGD PMID:18082289 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 acts_upstream_of_or_within ISO
IEA		 (MGI:5508628|PMID:16858406)
GO_REF:0000107		 RGD
Ensembl		 PMID:16858406 GO_REF:0000107 MGI:5508628 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 acts_upstream_of IMP PMID:30120945 ARUK-UCL PMID:30120945, PMID:30120945 RGD:30309911, RGD:30309911 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:15107418) RGD PMID:15107418 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:21050448) RGD PMID:21050448 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (MGI:5447631|PMID:10692450) RGD PMID:10692450 MGI:5447631 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO (PMID:16723520)
(MGI:3603971|PMID:16183742)		 RGD PMID:16183742 PMID:16723520 MGI:3603971 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfsf15 TNF superfamily member 15 involved_in IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:11911831)		 Ensembl
RGD		 PMID:11911831, PMID:11911831, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:634236, RGD:13792537, RGD:13792537 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073 		JBrowse link
G Vcp valosin-containing protein acts_upstream_of_or_within ISO (MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:2684521 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953 		JBrowse link
G Xdh xanthine dehydrogenase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18386220)		 Ensembl
RGD		 PMID:18386220 GO_REF:0000107 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 involved_in ISO (PMID:9267021) RGD PMID:9267021 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:2159364 (MGI:2178486|PMID:11836241) RGD PMID:11836241 MGI:2178486 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:15214043)
MGI:1857429 (MGI:1203837|PMID:9560217), (MGI:2178486|PMID:11836241)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9560217 PMID:11836241 PMID:15214043 GO_REF:0000024 GO_REF:0000107 MGI:1203837 MGI:2178486 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568)		 UniProt
RGD		 PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504 		JBrowse link
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:24091666) RGD PMID:24091666 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339 		JBrowse link
G Cycs cytochrome c, somatic acts_upstream_of_or_within ISO MGI:2154447|MGI:3581449 (MGI:1858667|PMID:10830166), (MGI:2681362|PMID:14623868), (MGI:3580764|PMID:15907471) RGD PMID:10830166 PMID:14623868 PMID:15907471 MGI:1858667 MGI:2681362 MGI:3580764 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2681362|PMID:14623868)
PMID:21873635		 RGD PMID:14623868, PMID:21873635, PMID:21873635 MGI:2681362, RGD:13792537, RGD:13792537 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330 		JBrowse link
G LOC100360940 diablo-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:147,607,350...147,608,936
Ensembl chr 5:147,607,552...147,609,050 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:1344924|PMID:10479688)		 Ensembl
RGD		 PMID:10479688 GO_REF:0000107 MGI:1344924 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:5009182 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Smad3 SMAD family member 3 IMP TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Ghr growth hormone receptor involved_in IDA PMID:8063815 RGD
BHF-UCL		 PMID:11244571, PMID:8063815, PMID:8063815 RGD:1624962, RGD:8553732, RGD:8553732 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:63384|PMID:8378315) RGD PMID:8378315 MGI:63384 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il4 interleukin 4 involved_in ISO
IBA		 UniProtKB:P08575 (PMID:12574355)
PMID:21873635		 RGD PMID:12574355, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4457458|PMID:20304997)		 UniProt
RGD		 PMID:20304997 GO_REF:0000024 MGI:4457458 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143 		JBrowse link
G Prl3d4 prolactin family 3, subfamily d, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:39,271,883...39,278,716
Ensembl chr17:39,272,004...39,278,695 		JBrowse link
G Prlr prolactin receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:10585417)		 Ensembl
RGD		 PMID:10585417 GO_REF:0000107 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO		 (PMID:8670418) RGD PMID:8670418, PMID:11818507 RGD:633057 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656 		JBrowse link
activation of JNKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102 (MGI:3654809|PMID:16319174) RGD PMID:16319174 MGI:3654809 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:84,473,178...84,491,689
Ensembl chr 1:84,473,071...84,491,466 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 IDA RGD PMID:17064355 RGD:2298577 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5810221|PMID:27511108)		 Ensembl
RGD		 PMID:27511108 GO_REF:0000107 MGI:5810221 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (MGI:5810221|PMID:27511108) RGD PMID:27511108 MGI:5810221 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357 		JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:58,744,995...58,779,408
Ensembl chr19:58,746,313...58,776,935 		JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:105,455,461...105,518,974
Ensembl chr 6:105,459,706...105,518,748 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 acts_upstream_of_or_within ISO (MGI:1344829|PMID:10471813) RGD PMID:10471813 MGI:1344829 NCBI chr 3:111,767,126...111,817,103
Ensembl chr 3:111,767,161...111,818,089 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851 		JBrowse link
G Nrk Nik related kinase acts_upstream_of_or_within ISO (MGI:1860727|PMID:10801798) RGD PMID:10801798 MGI:1860727 NCBI chr  X:109,940,439...110,036,361
NCBI chr  X:110,065,199...110,089,124
Ensembl chr  X:109,940,350...110,033,085 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase involved_in ISO (PMID:10521462), (PMID:15342639) RGD PMID:10521462 PMID:15342639 NCBI chr 2:113,984,599...114,391,805
Ensembl chr 2:113,984,646...114,384,894 		JBrowse link
activation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:5284790|PMID:16027136) RGD PMID:16027136 MGI:5284790 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15067037)		 Ensembl
UniProt
RGD		 PMID:15067037 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein TAS RGD PMID:12198159 RGD:1298803 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO (MGI:5442512|PMID:15894542) RGD PMID:15894542 MGI:5442512 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA		 (PMID:12813029)
GO_REF:0000107		 RGD
Ensembl		 PMID:12813029 GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102 (MGI:3654809|PMID:16319174) RGD PMID:16319174 MGI:3654809 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:10650002)
(MGI:3777353|PMID:10650002)		 RGD PMID:10650002 MGI:3777353 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (MGI:3777353|PMID:10650002) RGD PMID:10650002 MGI:3777353 NCBI chr 1:192,126,023...192,142,865
Ensembl chr 1:192,126,023...192,142,854 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 involved_in IMP
IDA		 PMID:9668039 RGD
MGI		 PMID:9668039, PMID:9668039, PMID:9668039 RGD:1299389, RGD:1299389, RGD:1299389 NCBI chr11:88,699,222...88,796,677
Ensembl chr11:88,699,222...88,796,677 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within ISO MGI:2667211 (MGI:2664443|PMID:12808090) RGD PMID:12808090 MGI:2664443 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008 		JBrowse link
G Ins2 insulin 2 NOT
NOT|acts_upstream_of_or_within		 ISO (MGI:2387283|PMID:12059784) RGD PMID:12059784 MGI:2387283 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:17064355, PMID:21873635, PMID:21873635, PMID:12524169 RGD:2298577, RGD:13792537, RGD:13792537, RGD:2298708 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
ISO
IBA		 (MGI:2182169|PMID:11959862)
PMID:21873635		 RGD PMID:11959862, PMID:10051439, PMID:21873635, PMID:21873635, PMID:17064355, PMID:11849756 MGI:2182169, RGD:2298561, RGD:13792537, RGD:13792537, RGD:2298577, RGD:2298565 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:1890011|PMID:10523642), (MGI:3032484|PMID:14967141)
(MGI:3032484|PMID:14967141)		 RGD PMID:10523642 PMID:14967141 MGI:1890011 MGI:3032484 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:84,473,178...84,491,689
Ensembl chr 1:84,473,071...84,491,466 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO
IBA		 (PMID:15258589)
PMID:21873635		 RGD PMID:15258589, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in IEA
ISO
IBA		 GO_REF:0000107
(MGI:5810221|PMID:27511108)
PMID:21873635		 Ensembl
RGD		 PMID:27511108, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:5810221, RGD:13792537, RGD:13792537 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO
IBA		 (MGI:5810221|PMID:27511108)
PMID:21873635		 RGD PMID:27511108, PMID:21873635, PMID:21873635 MGI:5810221, RGD:13792537, RGD:13792537 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369 		JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr19:58,744,995...58,779,408
Ensembl chr19:58,746,313...58,776,935 		JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 6:105,455,461...105,518,974
Ensembl chr 6:105,459,706...105,518,748 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 involved_in ISO (PMID:8824585) RGD PMID:8824585 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:221,710,622...221,726,274
Ensembl chr 1:221,710,670...221,725,656 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 PMID:21076496
(MGI:3575843|PMID:15767678)
PMID:21873635		 RGD PMID:15767678, PMID:21076496, PMID:21873635, PMID:21076496, PMID:21873635 MGI:3575843, RGD:13673827, RGD:13792537, RGD:13673827, RGD:13792537 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167 		JBrowse link
G Mdfi MyoD family inhibitor involved_in ISO (MGI:4441137|PMID:12192039) RGD PMID:12192039 MGI:4441137 NCBI chr 9:15,166,118...15,184,469
Ensembl chr 9:15,166,118...15,184,468 		JBrowse link
G Mdfic MyoD family inhibitor domain containing involved_in ISO (PMID:12192039) RGD PMID:12192039 NCBI chr 4:42,202,546...42,282,499
Ensembl chr 4:42,202,838...42,282,496 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5616322|PMID:15465829) RGD PMID:15465829 MGI:5616322 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735 		JBrowse link
G Spag9 sperm associated antigen 9 acts_upstream_of_or_within
involved_in		 IBA
ISO		 PMID:21873635
(MGI:4835955|PMID:12391307)		 RGD PMID:12391307, PMID:21873635, PMID:21873635 MGI:4835955, RGD:13792537, RGD:13792537 NCBI chr10:81,693,736...81,827,562
Ensembl chr10:81,693,770...81,827,562 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2384078 (MGI:85068|PMID:9000133)		 Ensembl
RGD		 PMID:9000133 GO_REF:0000107 MGI:85068 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
G Tf transferrin involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:20032469), (PMID:20034610)
GO_REF:0000107		 RGD
Ensembl		 PMID:20032469 PMID:20034610 GO_REF:0000107 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
G Wnt7b Wnt family member 7B IDA RGD PMID:18177422 RGD:2292645 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723 		JBrowse link
activation of MAPK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:11891218 RGD:1304238 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987 		JBrowse link
G Agt angiotensinogen involved_in ISO (PMID:28283184) RGD PMID:28283184 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Alk ALK receptor tyrosine kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775 		JBrowse link
G App amyloid beta precursor protein involved_in IDA
IGI		 PMID:11404397 ARUK-UCL PMID:11404397, PMID:11404397, PMID:11404397, PMID:11404397 RGD:12790656, RGD:12790656, RGD:12790656, RGD:12790656 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Arrb1 arrestin, beta 1 IDA RGD PMID:12519791, PMID:12167719 RGD:1304268, RGD:631797 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 acts_upstream_of_or_within
involved_in		 IEA
ISO
IBA		 GO_REF:0000107
(MGI:3036216|PMID:12356727)
PMID:21873635		 Ensembl
RGD		 PMID:12356727, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:3036216, RGD:13792537, RGD:13792537 NCBI chr 1:261,365,590...261,371,519
Ensembl chr 1:261,365,590...261,371,508 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17202865), (PMID:22540193)		 Ensembl
RGD		 PMID:17202865 PMID:22540193 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318 		JBrowse link
G C1qtnf2 C1q and TNF related 2 acts_upstream_of_or_within ISO (MGI:3055459|PMID:15231994) RGD PMID:15231994 MGI:3055459 NCBI chr10:29,067,102...29,084,035
Ensembl chr10:29,067,102...29,084,035 		JBrowse link
G Cd74 CD74 molecule IDA RGD PMID:12782713 RGD:728220 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO
ISS		 (PMID:14676841)
GO_REF:0000024		 RGD
UniProt		 PMID:14676841 GO_REF:0000024 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO (PMID:10771023) RGD PMID:10771023 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:3847828|PMID:19307307) RGD PMID:19307307 MGI:3847828 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2153094 (MGI:1334930|PMID:10036240)		 Ensembl
RGD		 PMID:10036240 GO_REF:0000107 MGI:1334930 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510 		JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 involved_in ISO
IBA
ISS		 (PMID:23115081)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:23115081, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 1:82,267,381...82,279,145
Ensembl chr 1:82,267,381...82,279,145 		JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15755724), (PMID:9843378)		 Ensembl
RGD		 PMID:9843378 PMID:15755724 GO_REF:0000107 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483 		JBrowse link
G Egf epidermal growth factor acts_upstream_of_or_within ISO (MGI:85697|PMID:9030684) RGD PMID:9030684 MGI:85697 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epgn epithelial mitogen involved_in ISO (MGI:1934957|PMID:11278323) RGD PMID:11278323 MGI:1934957 NCBI chr14:18,627,103...18,635,135
Ensembl chr14:18,626,644...18,634,309 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO (PMID:22064321) RGD PMID:22064321 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:24506284) RGD PMID:24506284 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO
ISS		 (PMID:18441324)
GO_REF:0000024		 RGD
UniProt		 PMID:18441324 GO_REF:0000024 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:14975937) RGD PMID:14975937 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO MGI:3521833|MGI:3580390|MGI:3689997|MGI:3768912 (MGI:3513737|PMID:15569927), (MGI:3580203|PMID:15870281), (MGI:3772963|PMID:18184727) RGD PMID:15569927 PMID:15870281 PMID:18184727 MGI:3513737 MGI:3580203 MGI:3772963 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within ISO (MGI:2182234|PMID:11940581) RGD PMID:11940581 MGI:2182234 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008 		JBrowse link
G Gdf15 growth differentiation factor 15 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6101250|PMID:28953886)
GO_REF:0000107
(PMID:28953886)		 UniProt
RGD
Ensembl		 PMID:28953886 GO_REF:0000024 GO_REF:0000107 MGI:6101250 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gfral GDNF family receptor alpha like involved_in ISO (PMID:28953886)
(MGI:6101250|PMID:28953886)		 RGD PMID:28953886 MGI:6101250 NCBI chr 8:83,235,647...83,282,635
Ensembl chr 8:83,236,103...83,280,888 		JBrowse link
G Ghr growth hormone receptor involved_in IDA PMID:8063815 BHF-UCL PMID:8063815, PMID:8063815 RGD:8553732, RGD:8553732 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO
ISS		 (PMID:15350694)
GO_REF:0000024		 RGD
UniProt		 PMID:15350694 GO_REF:0000024 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (MGI:5707553|PMID:26375174) RGD PMID:26375174 MGI:5707553 NCBI chr13:42,008,642...42,220,737
Ensembl chr13:42,008,842...42,009,738 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1934687|PMID:11356865)		 Ensembl
RGD		 PMID:11356865 GO_REF:0000107 MGI:1934687 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in ISO (PMID:15102938) RGD PMID:15102938 NCBI chr20:6,745,682...6,791,521
Ensembl chr20:6,745,682...6,791,519 		JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:22351760)
GO_REF:0000107		 RGD
Ensembl		 PMID:22351760 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 involved_in ISO
ISS		 (PMID:24003225)
GO_REF:0000024		 RGD
UniProt		 PMID:24003225 GO_REF:0000024 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO MGI:3707541 (MGI:5291883|PMID:21822257) RGD PMID:21822257 MGI:5291883 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA		 (PMID:10748004)
GO_REF:0000107		 RGD
Ensembl		 PMID:10748004 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:53,088,438...53,108,713
Ensembl chr13:53,088,439...53,108,713 		JBrowse link
G Ins1 insulin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:272,799,784...272,800,351
Ensembl chr 1:272,799,784...272,800,347 		JBrowse link
G Ins2 insulin 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2387283|PMID:12059784)
PMID:21873635		 RGD PMID:12059784, PMID:21873635, PMID:21873635 MGI:2387283, RGD:13792537, RGD:13792537 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Insr insulin receptor involved_in ISO
IEA		 (PMID:17001305)
GO_REF:0000107		 RGD
Ensembl		 PMID:17001305 GO_REF:0000107 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 acts_upstream_of_or_within ISO (MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:3835718 NCBI chr 2:187,447,477...187,489,630
Ensembl chr 2:187,447,501...187,489,630 		JBrowse link
G Itga1 integrin subunit alpha 1 IMP hippocampal neurons in response to beta-amyloid RGD PMID:14991844 RGD:2302385 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421 		JBrowse link
G Kars lysyl-tRNA synthetase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:44,212,205...44,231,209
Ensembl chr19:44,212,206...44,231,157 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:21640708) RGD PMID:21640708 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) RGD PMID:15755723 MGI:3584233 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584 		JBrowse link
G Lpar2 lysophosphatidic acid receptor 2 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) RGD PMID:15755723 MGI:3584233 NCBI chr16:21,343,313...21,348,913
Ensembl chr16:21,344,456...21,348,391 		JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 acts_upstream_of_or_within ISO (MGI:3584233|PMID:15755723) RGD PMID:15755723 MGI:3584233 NCBI chr 2:252,090,634...252,159,221
Ensembl chr 2:252,090,669...252,159,903 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584 		JBrowse link
G Madd MAP-kinase activating death domain involved_in IEA
ISO
ISS
IBA		 GO_REF:0000107
(MGI:3700423|PMID:14735464)
GO_REF:0000024
(PMID:9115275)
PMID:21873635		 Ensembl
RGD
UniProt		 PMID:9115275 PMID:14735464, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3700423, RGD:13792537, RGD:13792537 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 acts_upstream_of_or_within
involved_in		 IDA
ISO
TAS
IEA
IBA		 (MGI:3579196|PMID:15896720)
PMID:19565474
GO_REF:0000107
(PMID:10644344)
PMID:21873635		 RGD
Ensembl		 PMID:10644344 PMID:15896720, PMID:7935430, PMID:19565474, PMID:21873635, PMID:21873635, PMID:19565474 GO_REF:0000107 MGI:3579196, RGD:2293305, RGD:8553538, RGD:13792537, RGD:13792537, RGD:8553538 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS
IBA		 PMID:19565474
PMID:21873635		 UniProt
GO_Central		 PMID:19565474, PMID:19565474, PMID:21873635, PMID:21873635 RGD:8553538, RGD:8553538, RGD:13792537, RGD:13792537 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2385922|MGI:3581033 (MGI:2152033|PMID:11593045), (MGI:3575843|PMID:15767678)
PMID:21873635		 RGD PMID:11593045 PMID:15767678, PMID:21873635, PMID:21873635 MGI:2152033 MGI:3575843, RGD:13792537, RGD:13792537 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP
IBA		 PMID:20551324
PMID:21873635		 BHF-UCL
GO_Central		 PMID:20551324, PMID:20551324, PMID:21873635, PMID:21873635 RGD:8553940, RGD:8553940, RGD:13792537, RGD:13792537 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:8663524), (PMID:9218798)
MGI:2385922|MGI:3581034 (MGI:2152033|PMID:11593045), (MGI:3032469|PMID:14744933), (MGI:3575843|PMID:15767678)
PMID:21873635		 RGD PMID:8663524 PMID:9218798 PMID:11593045 PMID:14744933 PMID:15767678, PMID:21873635, PMID:21873635 MGI:2152033 MGI:3032469 MGI:3575843, RGD:13792537, RGD:13792537 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IEA
IBA		 GO_REF:0000108
PMID:21873635		 GOC PMID:21873635, PMID:21873635 GO_REF:0000108, RGD:13792537, RGD:13792537 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:15258589) RGD PMID:15258589 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 NAS RGD PMID:11359865 RGD:724475 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 acts_upstream_of_or_within ISO (MGI:3575843|PMID:15767678) RGD PMID:15767678 MGI:3575843 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:9079627) RGD PMID:9079627 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO UniProtKB:Q8BUE7 (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:80462|PMID:8631259), (MGI:81559|PMID:8692939)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8631259 PMID:8692939 GO_REF:0000024 GO_REF:0000107 MGI:80462 MGI:81559 NCBI chr 5:16,746,085...16,747,392
Ensembl chr 5:16,746,197...16,747,222 		JBrowse link
G Muc20 mucin 20, cell surface associated acts_upstream_of_or_within
involved_in		 ISO
IBA		 PR:P16056 (MGI:3054501|PMID:15314156)
PMID:21873635		 RGD PMID:15314156, PMID:21873635, PMID:21873635 MGI:3054501, RGD:13792537, RGD:13792537 NCBI chr11:71,222,602...71,236,223
Ensembl chr11:71,222,600...71,236,223 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
ISS		 (PMID:20682778)
GO_REF:0000024		 RGD
UniProt		 PMID:20682778 GO_REF:0000024 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Ntf3 neurotrophin 3 involved_in ISO
IEA		 (PMID:23027130)
GO_REF:0000107		 RGD
Ensembl		 PMID:23027130 GO_REF:0000107 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3700006|PMID:17306762) RGD PMID:17306762 MGI:3700006 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042 		JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669 		JBrowse link
G Pde6g phosphodiesterase 6G acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2156093|PMID:11502744)
PMID:21873635		 RGD PMID:11502744, PMID:21873635, PMID:21873635 MGI:2156093, RGD:13792537, RGD:13792537 NCBI chr10:109,620,499...109,625,214
Ensembl chr10:109,620,980...109,622,745 		JBrowse link
G Pde6h phosphodiesterase 6H acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2156093|PMID:11502744)
PMID:21873635		 RGD PMID:11502744, PMID:21873635, PMID:21873635 MGI:2156093, RGD:13792537, RGD:13792537 NCBI chr 4:170,947,723...170,963,046
Ensembl chr 4:170,958,196...170,963,046 		JBrowse link
G Phb2 prohibitin 2 NOT
NOT|involved_in		 ISO
ISS		 (PMID:24003225)
GO_REF:0000024		 RGD
UniProt		 PMID:24003225 GO_REF:0000024 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:15528384), (PMID:16005851) RGD PMID:15528384 PMID:16005851 NCBI chr12:46,879,346...46,890,234
Ensembl chr12:46,879,343...46,889,082 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:11022047)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11022047 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:15130913)
GO_REF:0000024		 RGD
UniProt		 PMID:15130913 GO_REF:0000024 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (MGI:3758374|PMID:17325201)		 Ensembl
RGD		 PMID:17325201 GO_REF:0000107 MGI:3758374 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094 		JBrowse link
G Prok1 prokineticin 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2663313|PMID:12746324)
PMID:21873635		 RGD PMID:12746324, PMID:21873635, PMID:21873635 MGI:2663313, RGD:13792537, RGD:13792537 NCBI chr 2:209,986,503...209,994,438
Ensembl chr 2:209,987,992...209,993,250 		JBrowse link
G Prok2 prokineticin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:132,157,556...132,171,244
Ensembl chr 4:132,157,556...132,171,153 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:2176524|MGI:3050284 (MGI:2679752|PMID:12937170), (MGI:3047525|PMID:15273746) RGD PMID:12937170 PMID:15273746 MGI:2679752 MGI:3047525 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:1095647|PMID:9254656) RGD PMID:9254656 MGI:1095647 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692 		JBrowse link
G Pxn paxillin acts_upstream_of_or_within ISO (MGI:2680875|PMID:14636584) RGD PMID:14636584 MGI:2680875 NCBI chr12:46,797,953...46,845,107
Ensembl chr12:46,797,954...46,845,080 		JBrowse link
G Ret ret proto-oncogene involved_in ISS
ISO		 GO_REF:0000024
(PMID:28953886)		 UniProt
RGD		 PMID:28953886 GO_REF:0000024 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372 		JBrowse link
G Sbk2 SH3 domain binding kinase family, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:72,425,728...72,433,494
Ensembl chr 1:72,425,707...72,433,488 		JBrowse link
G Shc1 SHC adaptor protein 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA
IBA		 MGI:2384189 (MGI:1858547|PMID:10809671)
GO_REF:0000107
(PMID:14676841), (PMID:20624904)
PMID:21873635		 RGD
Ensembl		 PMID:10809671 PMID:14676841 PMID:20624904, PMID:15262993, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:1858547, RGD:1580336, RGD:13792537, RGD:13792537 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066 		JBrowse link
G Shc2 SHC adaptor protein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:12,948,952...12,971,174
Ensembl chr 7:12,948,952...12,971,174 		JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in		 ISS
ISO		 GO_REF:0000024
(MGI:2387280|PMID:12223545)		 UniProt
RGD		 PMID:12223545 GO_REF:0000024 MGI:2387280 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Spag9 sperm associated antigen 9 acts_upstream_of_or_within ISO (MGI:3575843|PMID:15767678) RGD PMID:15767678 MGI:3575843 NCBI chr10:81,693,736...81,827,562
Ensembl chr10:81,693,770...81,827,562 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in IMP
ISO		 PMID:10980603
(PMID:10980603)		 RGD PMID:10980603, PMID:10980603, PMID:10980603 RGD:727300, RGD:727300 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO MGI:2384078 (MGI:79455|PMID:8626447), (MGI:85068|PMID:9000133) RGD PMID:8626447 PMID:9000133 MGI:79455 MGI:85068 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 involved_in ISO (PMID:9013573) RGD PMID:9013573 NCBI chr 8:119,215,266...119,220,909
Ensembl chr 8:119,215,495...119,219,232 		JBrowse link
G Tgfa transforming growth factor alpha involved_in ISO
ISS
IBA		 (PMID:11278323)
GO_REF:0000024
PMID:21873635		 RGD
HGNC-UCL
HGNC		 PMID:11278323, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:14605008 RGD:1579859 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:17413041) RGD PMID:17413041 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4421230|PMID:20051628)		 Ensembl
RGD		 PMID:20051628 GO_REF:0000107 MGI:4421230 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tp73 tumor protein p73 IMP RGD PMID:17353261 RGD:2291838 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:20034610) RGD PMID:20034610 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
activation of MAPKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07038021.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr  X:37,342,608...37,353,156 JBrowse link
G AABR07038029.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr  X:37,643,169...37,705,263 JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:17704059) RGD PMID:17704059 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926 		JBrowse link
G Adora1 adenosine A1 receptor IDA RGD PMID:12764156 RGD:1625267 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:1,369,534...1,391,603
Ensembl chr  X:1,379,194...1,390,873 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17600318), (PMID:17992660)		 Ensembl
UniProt
RGD		 PMID:17600318 PMID:17992660 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase involved_in ISO (PMID:29433126) RGD PMID:29433126 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Cartpt CART prepropeptide involved_in IDA
ISO		 PMID:15908120
(MGI:3696614|PMID:15908120)		 RGD PMID:15908120, PMID:15908120, PMID:15908120 MGI:3696614, RGD:8554672, RGD:8554672 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269 		JBrowse link
G Egf epidermal growth factor acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) RGD PMID:16339969 MGI:3614383 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:14551192 RGD:1581912 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISO
ISS		 (PMID:15229216)
GO_REF:0000024		 RGD
UniProt		 PMID:15229216 GO_REF:0000024 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201 		JBrowse link
G F2r coagulation factor II (thrombin) receptor IMP RGD PMID:12372796 RGD:728482 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) RGD PMID:16339969 MGI:3614383 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IMP RGD PMID:12062723 RGD:1582498 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta acts_upstream_of_or_within ISO (MGI:2387532|PMID:12213961) RGD PMID:12213961 MGI:2387532 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma acts_upstream_of_or_within ISO (MGI:2387532|PMID:12213961) RGD PMID:12213961 MGI:2387532 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1934687|PMID:11356865)		 Ensembl
RGD		 PMID:11356865 GO_REF:0000107 MGI:1934687 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859 		JBrowse link
G Jak2 Janus kinase 2 IMP insulin induced RGD PMID:16567515 RGD:1641817 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Kiss1r KISS1 receptor IDA RGD PMID:11457843 RGD:1357971 NCBI chr 7:12,606,210...12,609,868
Ensembl chr 7:12,606,210...12,609,868 		JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 acts_upstream_of_or_within ISO (MGI:3693387|PMID:15263099) RGD PMID:15263099 MGI:3693387 NCBI chr 2:187,911,530...187,914,930
Ensembl chr 2:187,911,533...187,915,596 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 acts_upstream_of_or_within ISO (MGI:3693387|PMID:15263099) RGD PMID:15263099 MGI:3693387 NCBI chr 2:243,160,821...243,173,057
Ensembl chr 2:243,160,917...243,173,048 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:19302196) RGD PMID:19302196 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999, PMID:7624324 RGD:2293488, RGD:1582177 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:11726277) RGD PMID:11726277 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:91,303,428...91,353,601
Ensembl chr10:91,303,428...91,353,601 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:9305639), (PMID:9827804) RGD PMID:9305639 PMID:9827804 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IBA		 (PMID:11959862)
PMID:21873635		 RGD PMID:11959862, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in IDA
ISO		 (PMID:8663074), (PMID:9079627) RGD PMID:8663074 PMID:9079627, PMID:16183734 RGD:2298758 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:16,746,085...16,747,392
Ensembl chr 5:16,746,197...16,747,222 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (MGI:3579196|PMID:15896720) RGD PMID:15896720 MGI:3579196 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:10644344) RGD PMID:10644344 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699 		JBrowse link
G Taok2 TAO kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10660600)		 Ensembl
RGD		 PMID:10660600 GO_REF:0000107 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (PMID:18625725) RGD PMID:18625725 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635 		JBrowse link
activation of MAPKKK activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134 (PMID:15190117) RGD PMID:15190117 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
ISS		 (PMID:19903888)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:9827804)		 Ensembl
RGD		 PMID:9827804, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta involved_in ISO
IBA		 (PMID:9827804)
PMID:21873635		 RGD PMID:9827804, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma involved_in ISO
IBA		 (PMID:9827804)
PMID:21873635		 RGD PMID:9827804, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IDA PMID:15758184 UniProt PMID:15758184, PMID:15758184 RGD:8554618, RGD:8554618 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392 		JBrowse link
G Ksr1 kinase suppressor of ras 1 involved_in ISO (PMID:29433126) RGD PMID:29433126 NCBI chr10:66,323,704...66,342,469
NCBI chr10:66,346,100...66,482,396
Ensembl chr10:66,347,358...66,482,150 		JBrowse link
G LOC100910771 mitogen-activated protein kinase kinase kinase 7-like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:114,022,058...114,077,887
Ensembl chr 9:114,022,137...114,079,089 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:221,710,622...221,726,274
Ensembl chr 1:221,710,670...221,725,656 		JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:3,276,732...3,444,519
Ensembl chr 6:3,276,738...3,444,519 		JBrowse link
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:92,136,242...92,229,578
Ensembl chr 6:92,136,992...92,229,260 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 acts_upstream_of_or_within ISO MGI:2667182 (MGI:2447107|PMID:12464436) RGD PMID:12464436 MGI:2447107 NCBI chr 7:121,350,953...121,382,100
Ensembl chr 7:121,350,965...121,382,088 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:15310755) RGD PMID:15310755 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO (PMID:14743216) RGD PMID:14743216 NCBI chr10:13,874,444...13,893,090
Ensembl chr10:13,874,456...13,892,997 		JBrowse link
activation of NF-kappaB-inducing kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (MGI:3844151|PMID:19404405) RGD PMID:19404405 MGI:3844151 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Card10 caspase recruitment domain family, member 10 involved_in ISO (PMID:11259443) RGD PMID:11259443 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026 		JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306542|PMID:21546314)		 UniProt
RGD		 PMID:21546314 GO_REF:0000024 MGI:5306542 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Cops8 COP9 signalosome subunit 8 involved_in ISO (PMID:22992343) RGD PMID:22992343 NCBI chr 9:97,772,224...97,782,055
Ensembl chr 9:97,772,184...97,782,067 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma acts_upstream_of_or_within ISO (MGI:2682548|PMID:14654787) RGD PMID:14654787 MGI:2682548 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:11397809) RGD PMID:11397809 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 NOT
NOT|acts_upstream_of_or_within		 ISO (MGI:2388552|PMID:12220507) RGD PMID:12220507 MGI:2388552 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:10094049), (PMID:15125833) RGD PMID:10094049 PMID:15125833 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor acts_upstream_of_or_within ISO MGI:2158808 (MGI:3844151|PMID:19404405) RGD PMID:19404405 MGI:3844151 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:24275656) RGD PMID:24275656 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224 		JBrowse link
G Tnfsf15 TNF superfamily member 15 involved_in ISO
IEA		 (PMID:11911831)
GO_REF:0000107		 RGD
Ensembl		 PMID:11911831 GO_REF:0000107 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607 		JBrowse link
G Zfp91 zinc finger protein 91 involved_in ISO (PMID:20682767) RGD PMID:20682767 NCBI chr 1:229,602,499...229,640,906
Ensembl chr 1:229,602,499...229,639,187 		JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 involved_in IMP PMID:25381556 UniProt PMID:25381556, PMID:25381556 RGD:13825194, RGD:13825194 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:27087445) RGD PMID:27087445 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120 		JBrowse link
G Prrc1 proline-rich coiled-coil 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:52,423,845...52,460,854
Ensembl chr18:52,423,883...52,457,575 		JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974 		JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07026997.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr17:9,233,514...9,234,766 JBrowse link
G AABR07032328.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr18:61,231,234...61,231,515 JBrowse link
G AABR07049960.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 5:146,294,030...146,296,221 JBrowse link
G Acvr2b activin A receptor type 2B acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3701721|PMID:16806156)		 Ensembl
RGD		 PMID:16806156 GO_REF:0000107 MGI:3701721 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746 		JBrowse link
G Adnp activity-dependent neuroprotector homeobox IDA Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:15653687) RGD PMID:15653687 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422 		JBrowse link
G Axin1 axin 1 involved_in ISO (PMID:9601641) RGD PMID:9601641
G Bora bora, aurora kinase A activator involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr15:83,442,217...83,463,737
Ensembl chr15:83,442,144...83,463,717 		JBrowse link
G Cab39 calcium binding protein 39 acts_upstream_of_or_within ISO (MGI:3836081|PMID:18854309) RGD PMID:18854309 MGI:3836081 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:17983652) RGD PMID:17983652 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:16054095 RGD:2311420 NCBI chr10:59,585,023...59,608,180
Ensembl chr10:59,585,072...59,608,165 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 IDA RGD PMID:16054095 RGD:2311420 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601 		JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (PMID:21954290) RGD PMID:21954290 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263 		JBrowse link
G Ccnq cyclin Q involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:66,019,519...66,020,682
Ensembl chr10:66,019,520...66,020,682 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (PMID:16885022)
PMID:21873635		 RGD PMID:16885022, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Daxx death-domain associated protein involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3697750|PMID:17187070)		 Ensembl
RGD		 PMID:17187070 GO_REF:0000107 MGI:3697750 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:67,849,966...67,862,475
Ensembl chr 3:67,849,966...67,862,475 		JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:15254234) RGD PMID:15254234 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476 		JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISO
ISS		 (PMID:21637765)
GO_REF:0000024		 RGD
UniProt		 PMID:21637765 GO_REF:0000024 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839 		JBrowse link
G Epo erythropoietin involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:188,688,743...188,713,724
Ensembl chr 1:188,688,743...188,713,280 		JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:103,395,222...103,417,360
Ensembl chr10:103,395,511...103,417,358 		JBrowse link
G Gprc5d G protein-coupled receptor, class C, group 5, member D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:168,872,897...168,884,925
Ensembl chr 4:168,872,897...168,884,886 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:9819385) RGD PMID:9819385 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO (PMID:10022831) RGD PMID:10022831 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:24784001) RGD PMID:24784001 NCBI chr13:53,350,073...53,421,992
Ensembl chr13:53,351,717...53,420,111 		JBrowse link
G LOC100360522 ribosomal protein P1-like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:9,233,473...9,234,857
Ensembl chr 8:66,862,143...66,863,476 		JBrowse link
G LOC100910732 serine/threonine-protein kinase PAK 2-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr11:71,959,058...72,021,252
Ensembl chr11:71,959,228...72,021,224 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:130,430,588...130,440,838
Ensembl chr 7:130,431,213...130,440,703 		JBrowse link
G Mink1 misshapen-like kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:57,185,310...57,238,531
Ensembl chr10:57,185,347...57,238,531 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507 		JBrowse link
G Nrk Nik related kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr  X:109,940,439...110,036,361
NCBI chr  X:110,065,199...110,089,124
Ensembl chr  X:109,940,350...110,033,085 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902 		JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669 		JBrowse link
G Pak4 p21 (RAC1) activated kinase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:85,162,462...85,201,746
Ensembl chr 1:85,162,452...85,201,757 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:129,042,232...129,357,512
Ensembl chr 3:129,042,742...129,357,491 		JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:110,442,175...110,486,317
Ensembl chr 3:110,442,637...110,487,526 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS		 (PMID:16530387)
GO_REF:0000024		 RGD
UniProt		 PMID:16530387 GO_REF:0000024 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within ISO MGI:3759678 (MGI:3589325|PMID:16129705) RGD PMID:16129705 MGI:3589325 NCBI chr 6:76,056,585...76,079,755
Ensembl chr 6:76,056,499...76,079,664 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:10713049)
GO_REF:0000107		 RGD
Ensembl		 PMID:10713049 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Prnp prion protein involved_in ISO ComplexPortal:CPX-1134 (MGI:5882868|PMID:23386614) RGD PMID:23386614 MGI:5882868 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316 		JBrowse link
G Rgcc regulator of cell cycle involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISO
ISS		 (PMID:22817896)
GO_REF:0000024		 RGD
UniProt		 PMID:22817896 GO_REF:0000024 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:66,862,143...66,863,476
Ensembl chr 8:66,862,143...66,863,476 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1857755 (MGI:64652|PMID:8301134)		 Ensembl
RGD		 PMID:8301134 GO_REF:0000107 MGI:64652 NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:23,493,686...23,543,236
Ensembl chr 6:23,498,511...23,543,172 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within
involved_in		 IEA
ISO
ISS		 GO_REF:0000107
(MGI:3836081|PMID:18854309)
(PMID:15731909)
(PMID:18854309)		 Ensembl
RGD		 PMID:15731909 PMID:18854309, PMID:15731909, PMID:15731909 GO_REF:0000107 MGI:3836081, RGD:13702324, RGD:13702324 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513 		JBrowse link
G Stk3 serine/threonine kinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812 		JBrowse link
G Stk4 serine/threonine kinase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540 		JBrowse link
G Strada STE20 related adaptor alpha acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 PMID:14511394
(MGI:3836081|PMID:18854309)
GO_REF:0000107
(PMID:12805220)		 RGD
Ensembl		 PMID:12805220 PMID:18854309, PMID:14511394, PMID:14511394 GO_REF:0000107 MGI:3836081, RGD:1600691, RGD:1600691 NCBI chr10:94,355,369...94,384,404
Ensembl chr10:94,355,384...94,384,339 		JBrowse link
G Stradb STE20 related adaptor beta involved_in ISO (PMID:14517248) RGD PMID:14517248 NCBI chr 9:65,763,437...65,782,513
Ensembl chr 9:65,763,437...65,782,513 		JBrowse link
G Taok1 TAO kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155 		JBrowse link
G Taok2 TAO kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075 		JBrowse link
G Taok3 TAO kinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:45,037,951...45,116,593
Ensembl chr12:45,037,883...45,182,974 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17192487), (PMID:17960115)		 UniProt
AgBase
RGD		 PMID:17192487 PMID:17960115 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO (MGI:3701721|PMID:16806156) RGD PMID:16806156 MGI:3701721 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:113,984,599...114,391,805
Ensembl chr 2:113,984,646...114,384,894 		JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:16479011)		 Ensembl
RGD		 PMID:16479011 GO_REF:0000107 NCBI chr10:78,173,847...78,219,805
Ensembl chr10:78,173,847...78,219,793 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:14580337), (PMID:19801554) RGD PMID:14580337 PMID:19801554 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) RGD PMID:17135271 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:18059339), (PMID:20497126) RGD PMID:18059339 PMID:20497126 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446 		JBrowse link
G Wnt11 Wnt family member 11 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756 		JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032503.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr18:68,925,186...68,934,953 JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987 		JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010 		JBrowse link
G Ang angiogenin involved_in ISO (PMID:17125737) RGD PMID:17125737 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (MGI:3581096|PMID:15753085) RGD PMID:15753085 MGI:3581096 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263 		JBrowse link
G Dynap dynactin associated protein involved_in ISO
IBA		 (PMID:20978158)
PMID:21873635		 RGD PMID:20978158, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:68,752,224...68,755,426
Ensembl chr18:68,752,227...68,755,426 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO
ISS		 (PMID:18441324)
GO_REF:0000024		 RGD
UniProt		 PMID:18441324 GO_REF:0000024 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Gas6 growth arrest specific 6 involved_in IDA PMID:18374201 UniProt PMID:18374201, PMID:18374201 RGD:8554638, RGD:8554638 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:22351760)
GO_REF:0000107		 RGD
Ensembl		 PMID:22351760 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21321938)		 Ensembl
RGD		 PMID:21321938 GO_REF:0000107 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8702995) RGD PMID:8702995 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Insr insulin receptor involved_in ISO
IEA		 (PMID:7556070)
GO_REF:0000107		 RGD
Ensembl		 PMID:7556070 GO_REF:0000107 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:43,348,927...43,363,633
Ensembl chr 6:43,348,958...43,363,335 		JBrowse link
G Mt3 metallothionein 3 involved_in ISO
ISS		 (PMID:18295594)
GO_REF:0000024		 RGD
UniProt		 PMID:18295594 GO_REF:0000024 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
ISS		 (PMID:20682778)
GO_REF:0000024		 RGD
UniProt		 PMID:20682778 GO_REF:0000024 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Ntf3 neurotrophin 3 involved_in ISO
IEA		 (PMID:23027130)
GO_REF:0000107		 RGD
Ensembl		 PMID:23027130 GO_REF:0000107 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 involved_in ISO (MGI:5644010|PMID:23812417) RGD PMID:23812417 MGI:5644010 NCBI chr 7:53,878,906...54,030,110
Ensembl chr 7:53,878,610...54,027,892 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:16530387)		 Ensembl
UniProt
RGD		 PMID:16530387 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:9368760) RGD PMID:9368760 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:23180369)
GO_REF:0000024		 RGD
UniProt		 PMID:23180369 GO_REF:0000024 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668 		JBrowse link
G Prkcz protein kinase C, zeta IMP in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:6478088|PMID:23827345) RGD PMID:23827345 MGI:6478088 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP PMID:16530387 UniProt PMID:16530387, PMID:16530387 RGD:8553998, RGD:8553998 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Tcl1a Tcl1 family Akt coactivator A involved_in ISO (MGI:6377804|PMID:28262547) RGD PMID:28262547 MGI:6377804 NCBI chr 6:128,888,768...128,894,761
Ensembl chr 6:128,888,768...128,894,761 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:20034610)
GO_REF:0000107		 RGD
Ensembl		 PMID:20034610 GO_REF:0000107 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
activation of protein kinase C activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:10713049) RGD PMID:10713049 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Cd86 CD86 molecule involved_in ISO (MGI:5461234|PMID:23241883) RGD PMID:23241883 MGI:5461234 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795 		JBrowse link
G Lep leptin involved_in ISO
ISS
IBA		 (PMID:24340098)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:24340098, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Phb prohibitin involved_in ISS
ISO		 GO_REF:0000024
(MGI:5461234|PMID:23241883)		 UniProt
RGD		 PMID:23241883 GO_REF:0000024 MGI:5461234 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878 		JBrowse link
G Phb2 prohibitin 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5461234|PMID:23241883)		 UniProt
RGD		 PMID:23241883 GO_REF:0000024 MGI:5461234 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367 		JBrowse link
activation of transmembrane receptor protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19424712)		 Ensembl
RGD		 PMID:19424712 GO_REF:0000107 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206 		JBrowse link
G Angpt4 angiopoietin 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:147,421,724...147,455,670
Ensembl chr 3:147,422,095...147,455,670 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO MGI:2155602 (MGI:3590443|PMID:16162937) RGD PMID:16162937 MGI:3590443 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989 		JBrowse link
G Ngf nerve growth factor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Nrg1 neuregulin 1 involved_in IBA
ISO		 PMID:21873635
(PMID:9553078)		 RGD PMID:9553078, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Pdgfc platelet derived growth factor C acts_upstream_of_or_within ISO (MGI:1858279|PMID:10806482) RGD PMID:10806482 MGI:1858279 NCBI chr 2:179,952,227...180,126,897
Ensembl chr 2:179,952,227...180,128,283 		JBrowse link
G Prlr prolactin receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:10585417)		 Ensembl
RGD		 PMID:10585417 GO_REF:0000107 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:18725990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18725990 GO_REF:0000107 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:81,509,185...81,516,759 JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:16254138) RGD PMID:16254138 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003 		JBrowse link
positive regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:15153556) RGD PMID:15153556 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Gh1 growth hormone 1 involved_in ISO (PMID:12552091), (PMID:8063815) RGD PMID:8063815 PMID:12552091 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12023369) RGD PMID:12023369 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IBA		 (PMID:12023369)
PMID:21873635		 RGD PMID:12023369, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723 		JBrowse link
G Il6r interleukin 6 receptor involved_in IBA
ISO		 PMID:21873635
(PMID:12419823)		 RGD PMID:12419823, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
positive regulation of amyloid fibril formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:19660551) RGD PMID:19660551 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:P05067 (PMID:11880515) RGD PMID:11880515 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798 		JBrowse link
positive regulation of amyloid precursor protein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (PMID:20704561) RGD PMID:20704561 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Ncstn nicastrin acts_upstream_of_or_within ISO (MGI:5569714|PMID:23826707) RGD PMID:23826707 MGI:5569714 NCBI chr13:90,451,046...90,467,256
Ensembl chr13:90,451,044...90,467,256 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3028747|PMID:14627703)		 Ensembl
RGD		 PMID:14627703 GO_REF:0000107 MGI:3028747 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068 		JBrowse link
G Soat1 sterol O-acyltransferase 1 involved_in ISO
IEA		 (PMID:17412327)
GO_REF:0000107		 RGD
Ensembl		 PMID:17412327 GO_REF:0000107 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783 		JBrowse link
positive regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO UniProtKB:P56818 (PMID:20704561), (PMID:22086926) RGD PMID:20704561 PMID:22086926 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Ranbp9 RAN binding protein 9 acts_upstream_of IGI PMID:24592211 ARUK-UCL PMID:24592211, PMID:24592211 RGD:38501074, RGD:38501074 NCBI chr17:24,020,874...24,103,771
Ensembl chr17:24,021,736...24,103,515 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:24305806)
(MGI:6114922|PMID:24305806)		 RGD PMID:24305806 MGI:6114922 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Spon1 spondin 1 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3607023|PMID:16227578)		 Ensembl
RGD		 PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr 1:178,568,777...178,935,715
Ensembl chr 1:178,636,544...178,935,051 		JBrowse link
positive regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in
acts_upstream_of		 ISO
IMP		 (PMID:22086926) RGD PMID:22086926, PMID:22086926, PMID:22086926 RGD:14697726, RGD:14697726 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17293612) RGD PMID:17293612 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:24154541), (PMID:24259049) RGD PMID:24154541 PMID:24259049 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Casp3 caspase 3 involved_in ISO
IDA		 (PMID:17553422) RGD PMID:17553422, PMID:17553422, PMID:17553422 RGD:13825190, RGD:13825190 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067 (MGI:4437154|PMID:20164328)		 Ensembl
RGD		 PMID:20164328 GO_REF:0000107 MGI:4437154 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Clu clusterin involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2384259|PMID:12145324)
GO_REF:0000024		 Ensembl
RGD
Alzheimers_University_of_Toronto		 PMID:12145324 GO_REF:0000024 GO_REF:0000107 MGI:2384259 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Csnk1e casein kinase 1, epsilon IDA RGD PMID:17360493 RGD:10395238 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (PMID:24217950) RGD PMID:24217950 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458 		JBrowse link
G Gsap gamma-secretase activating protein involved_in ISO
IBA		 (PMID:20811458)
(MGI:4830390|PMID:20811458)
PMID:21873635		 RGD PMID:20811458, PMID:21873635, PMID:21873635 MGI:4830390, RGD:13792537, RGD:13792537 NCBI chr 4:10,423,090...10,517,887
Ensembl chr 4:10,423,139...10,517,848 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO UniProtKB:P49841 (PMID:12761548) RGD PMID:12761548 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203 		JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:P05067|UniProtKB:P10636|UniProtKB:P49768 (PMID:19808651)
UniProtKB:P05067|UniProtKB:P15261 (MGI:3697769|PMID:17255335)		 RGD PMID:17255335 PMID:19808651 MGI:3697769 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P01579|UniProtKB:P05067 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907 		JBrowse link
G Lrrtm3 leucine rich repeat transmembrane neuronal 3 acts_upstream_of_or_within
involved_in		 ISO (PMID:17098871)
(MGI:3695648|PMID:17098871)		 RGD PMID:17098871 MGI:3695648 NCBI chr20:25,990,304...26,163,656
Ensembl chr20:25,990,304...26,163,656 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
ISS
IEA		 (PMID:24577224)
(MGI:5432454|PMID:22539346), (MGI:5560380|PMID:24577224)
GO_REF:0000024
GO_REF:0000107		 RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:22539346 PMID:24577224 GO_REF:0000024 GO_REF:0000107 MGI:5432454 MGI:5560380 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of ISO (MGI:6414694|PMID:21329555) RGD PMID:21329555 MGI:6414694 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6114922|PMID:24305806)
(PMID:24305806)		 Ensembl
RGD		 PMID:24305806 GO_REF:0000107 MGI:6114922 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Slc2a13 solute carrier family 2 member 13 involved_in ISO UniProtKB:P05067-4 (PMID:26094765) RGD PMID:26094765 NCBI chr 7:132,430,852...132,757,558
Ensembl chr 7:132,430,853...132,757,558 		JBrowse link
G Sp1 Sp1 transcription factor acts_upstream_of ISO (PMID:14701757) RGD PMID:14701757 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613 		JBrowse link
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067:PRO_0000000093 (PMID:22406537)		 Ensembl
RGD		 PMID:22406537 GO_REF:0000107 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q15109 (PMID:22406537) RGD PMID:22406537 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Efna1 ephrin A1 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222 		JBrowse link
G Efna3 ephrin A3 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:188,636,304...188,645,302
Ensembl chr 2:188,637,852...188,645,196 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827|UniProtKB:P52797 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:24217950) RGD PMID:24217950 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5432454|PMID:22539346)
GO_REF:0000024		 Ensembl
RGD
Alzheimers_University_of_Toronto		 PMID:22539346 GO_REF:0000024 GO_REF:0000107 MGI:5432454 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6114922|PMID:24305806)
(PMID:24305806)		 Ensembl
RGD		 PMID:24305806 GO_REF:0000107 MGI:6114922 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
positive regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5907533|PMID:28453791)
(PMID:28453791)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28453791 GO_REF:0000024 GO_REF:0000107 MGI:5907533 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(MGI:3795840|PMID:18431508)
(PMID:18431508), (PMID:19524870)		 UniProt
RGD		 PMID:18431508 PMID:19524870 GO_REF:0000024 MGI:3795840 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:11179196 BHF-UCL PMID:11179196, PMID:11179196 RGD:8553373, RGD:8553373 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO
ISS		 (PMID:16272156)
(MGI:5499726|PMID:16272156)
GO_REF:0000024		 RGD
UniProt		 PMID:16272156 GO_REF:0000024 MGI:5499726 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:18687677)
(MGI:5306579|PMID:18687677)
GO_REF:0000107		 RGD
Ensembl		 PMID:18687677 GO_REF:0000107 MGI:5306579 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Spatc1l spermatogenesis and centriole associated 1-like acts_upstream_of_or_within ISO (MGI:6199287|PMID:30026308) RGD PMID:30026308 MGI:6199287 NCBI chr20:12,825,789...12,835,007
Ensembl chr20:13,164,628...13,173,774
Ensembl chr20:13,164,628...13,173,774 		JBrowse link
positive regulation of cap-dependent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:11959995) RGD PMID:11959995 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
positive regulation of cap-independent translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl3 methyltransferase-like 3 involved_in ISO (PMID:26593424) RGD PMID:26593424 NCBI chr15:28,710,299...28,721,491
Ensembl chr15:28,710,300...28,721,127 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:11959995) RGD PMID:11959995 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 involved_in ISO (PMID:26458103) RGD PMID:26458103 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099 		JBrowse link
positive regulation of CD24 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcb1 phospholipase C beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4943410|PMID:15849202)
GO_REF:0000107		 BHF-UCL
RGD
Ensembl		 PMID:15849202 GO_REF:0000024 GO_REF:0000107 MGI:4943410 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545 		JBrowse link
positive regulation of CD80 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il33 interleukin 33 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:6414704|PMID:26936882)		 Ensembl
RGD		 PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029 		JBrowse link
positive regulation of CD86 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il33 interleukin 33 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:6414704|PMID:26936882)		 Ensembl
RGD		 PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029 		JBrowse link
positive regulation of cellular protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amer1 APC membrane recruitment protein 1 involved_in ISO (PMID:17510365) RGD PMID:17510365 NCBI chr  X:64,686,620...64,702,504
Ensembl chr  X:64,686,623...64,702,441 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in ISO (PMID:16446366), (PMID:18936100) RGD PMID:16446366 PMID:18936100 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809 		JBrowse link
G Ezr ezrin involved_in ISO UniProtKB:P26038|UniProtKB:P35241 (PMID:21148287) RGD PMID:21148287 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G Faf1 Fas associated factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26842564)		 Ensembl
RGD		 PMID:26842564 GO_REF:0000107 NCBI chr 5:129,370,767...129,738,393
Ensembl chr 5:129,448,879...129,738,252 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 acts_upstream_of_or_within ISO MGI:5295289 (MGI:5292406|PMID:21907140) RGD PMID:21907140 MGI:5292406 NCBI chr14:71,852,649...71,891,143
Ensembl chr14:71,852,682...71,891,143 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (MGI:5293184|PMID:21700773) RGD PMID:21700773 MGI:5293184 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO UniProtKB:Q9UNE7 (PMID:18292230) RGD PMID:18292230 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Msn moesin involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P15311|UniProtKB:P35241 (PMID:21148287)		 Ensembl
RGD		 PMID:21148287 GO_REF:0000107 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810 		JBrowse link
G Pttg1ip PTTG1 interacting protein involved_in ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,746,369...11,764,097
Ensembl chr20:11,746,370...11,764,233 		JBrowse link
G Rdx radixin involved_in ISO UniProtKB:P15311|UniProtKB:P26038 (PMID:21148287) RGD PMID:21148287 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 acts_upstream_of_or_within ISO (MGI:3839729|PMID:18952128) RGD PMID:18952128 MGI:3839729 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807 		JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 ISO
ISS		 (PMID:24385928)
GO_REF:0000024		 RGD
UniProt		 PMID:24385928 GO_REF:0000024 NCBI chr20:5,712,200...5,723,902
Ensembl chr20:5,712,203...5,723,902 		JBrowse link
G Vgll4 vestigial-like family member 4 involved_in ISO (MGI:6120600|PMID:27720608) RGD PMID:27720608 MGI:6120600 NCBI chr 4:146,778,556...146,890,063
Ensembl chr 4:146,779,276...146,839,397 		JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:21148287) RGD PMID:21148287 NCBI chr 8:48,677,492...48,692,295
Ensembl chr 8:48,677,492...48,692,295 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO UniProtKB:P37840 (PMID:25533483) RGD PMID:25533483 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636 		JBrowse link
positive regulation of cellular protein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IMP PMID:9632753 BHF-UCL PMID:9632753, PMID:9632753 RGD:8554450, RGD:8554450 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Csf1 colony stimulating factor 1 involved_in ISO
IEA		 (PMID:1739124)
GO_REF:0000107		 RGD
Ensembl		 PMID:1739124 GO_REF:0000107 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO (PMID:21828274) RGD PMID:21828274 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:3553851) RGD PMID:3553851 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (PMID:22430140) RGD PMID:22430140 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO
IEA		 (PMID:18511424)
GO_REF:0000107		 RGD
Ensembl		 PMID:18511424 GO_REF:0000107 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:21451101 RGD:10041071 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:15219857)
GO_REF:0000024		 RGD
UniProt		 PMID:15219857 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 involved_in ISO (PMID:10646863) RGD PMID:10646863 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954 		JBrowse link
G Wnt7a Wnt family member 7A involved_in ISO (PMID:16805831) RGD PMID:16805831 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609 		JBrowse link
positive regulation of chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISO (PMID:27344333) RGD PMID:27344333 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900 		JBrowse link
positive regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in IMP
ISO		 PMID:17517623
(MGI:6148636|PMID:17517623)		 RGD PMID:17517623, PMID:17517623, PMID:17517623 MGI:6148636, RGD:13514081, RGD:13514081 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243 		JBrowse link
G Stox1 storkhead box 1 involved_in ISO (PMID:22253775), (PMID:22995177) RGD PMID:22253775 PMID:22995177 NCBI chr20:32,276,857...32,353,677
Ensembl chr20:32,276,658...32,353,677 		JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:16,862,305...16,899,399
Ensembl chr 9:16,862,248...16,902,199 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049223.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr 5:110,831,936...110,832,175 JBrowse link
G AC112018.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr 4:142,970,009...142,970,245 JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA		 (PMID:18483258)
GO_REF:0000107		 RGD
Ensembl		 PMID:18483258 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Ccnb1 cyclin B1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Ccnd1 cyclin D1 involved_in ISO
ISS		 (PMID:8114739)
GO_REF:0000024		 RGD
UniProt		 PMID:8114739 GO_REF:0000024 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnd2 cyclin D2 involved_in ISO (PMID:8114739) RGD PMID:8114739 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207 		JBrowse link
G Ccnd3 cyclin D3 involved_in ISO
IEA		 (PMID:8114739)
GO_REF:0000107		 RGD
Ensembl		 PMID:8114739 GO_REF:0000107 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943 		JBrowse link
G Ccnk cyclin K involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557 		JBrowse link
G Ccnt1 cyclin T1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723 		JBrowse link
G Ccnt2 cyclin T2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:44,475,959...44,516,892
Ensembl chr13:44,475,970...44,515,739 		JBrowse link
G Ccny cyclin Y involved_in ISO
IBA		 (PMID:19524571), (PMID:20059949)
PMID:21873635		 RGD PMID:19524571 PMID:20059949, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:62,332,537...62,462,644
Ensembl chr17:62,332,537...62,462,644 		JBrowse link
G Ccnyl1 cyclin Y-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:71,398,186...71,434,581
Ensembl chr 9:71,398,710...71,434,493 		JBrowse link
G Cdc6 cell division cycle 6 IMP RGD PMID:22223646 RGD:10045360 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255 		JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:82,120,059...82,121,527
Ensembl chr 9:82,120,059...82,121,527 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 IDA RGD PMID:10721722 RGD:632478 NCBI chr 3:149,835,953...149,870,429
Ensembl chr 3:149,703,848...149,870,413 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22223646 RGD:10045360 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144 		JBrowse link
G Cks1l CDC28 protein kinase regulatory subunit 1-like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:110,831,843...110,832,242 JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) RGD PMID:24313324 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940 		JBrowse link
G LOC103692976 cyclin-T1-like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:140,149,991...140,172,615
Ensembl chr 7:140,154,490...140,172,448 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 involved_in ISO (MGI:3773778|PMID:17310996) RGD PMID:17310996 MGI:3773778 NCBI chr 6:26,878,738...26,923,459
Ensembl chr 6:26,878,744...26,889,882 		JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:16530387)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16530387 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:18593906) RGD PMID:18593906 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:19210544) RGD PMID:19210544 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS		 (PMID:11900540)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11900540 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in ISO (MGI:3773778|PMID:17310996) RGD PMID:17310996 MGI:3773778 NCBI chr 2:211,176,437...211,181,078
Ensembl chr 2:211,176,556...211,181,123 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:11687586), (PMID:19162005) RGD PMID:11687586 PMID:19162005 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:3617485|PMID:15611625)
PMID:21873635		 UniProt
RGD		 PMID:15611625, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:3617485, RGD:13792537, RGD:13792537 NCBI chr 6:23,493,686...23,543,236
Ensembl chr 6:23,498,511...23,543,172 		JBrowse link
G Spdye4 speedy/RINGO cell cycle regulator family member E4 involved_in ISO (MGI:3617485|PMID:15611625) RGD PMID:15611625 MGI:3617485 NCBI chr12:13,390,831...13,398,301
Ensembl chr12:13,390,859...13,398,295 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP PMID:16530387 UniProt PMID:16530387, PMID:16530387 RGD:8553998, RGD:8553998 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO (MGI:3586393|PMID:16024801) RGD PMID:16024801 MGI:3586393 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mastl microtubule associated serine/threonine kinase-like involved_in ISO (PMID:23843240) RGD PMID:23843240 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825 		JBrowse link
positive regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO (PMID:19158676), (PMID:19158679)
(MGI:3839523|PMID:19158676), (MGI:5437433|PMID:19131592)		 RGD PMID:19131592 PMID:19158676 PMID:19158679 MGI:3839523 MGI:5437433 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4879048|PMID:21159964), (MGI:5448480|PMID:22761832)		 UniProt
RGD		 PMID:21159964 PMID:22761832 GO_REF:0000024 MGI:4879048 MGI:5448480 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:17526495 ARUK-UCL PMID:17526495, PMID:17526495 RGD:13506268, RGD:13506268 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IGI PMID:17526495 ARUK-UCL PMID:17526495, PMID:17526495 RGD:13506268, RGD:13506268 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in IGI PMID:17526495 ARUK-UCL PMID:17526495, PMID:17526495 RGD:13506268, RGD:13506268 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873 		JBrowse link
G Mefv MEFV innate immuity regulator, pyrin involved_in ISO (PMID:19158676) RGD PMID:19158676 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311 		JBrowse link
G Nek5 NIMA-related kinase 5 acts_upstream_of_or_within ISO (MGI:5500844|PMID:23727203) RGD PMID:23727203 MGI:5500844 NCBI chr16:74,809,513...74,851,895
Ensembl chr16:74,810,938...74,848,113 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:19158676) RGD PMID:19158676 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210 		JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:16,862,305...16,899,399
Ensembl chr 9:16,862,248...16,902,199