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ONTOLOGY REPORT - ANNOTATIONS


Term:release of sequestered calcium ion into cytosol
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Accession:GO:0051209 term browser browse the term
Definition:The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
Synonyms:exact_synonym: cytosolic release of sequestered calcium ion (Ca2+);   cytosolic release of stored calcium ion (Ca2+);   release of stored calcium ion (Ca2+) into cytosol
 broad_synonym: calcium ion (Ca2+) mobilization;   calcium mobilization;   cytoplasmic release of sequestered calcium ion (Ca2+);   cytoplasmic release of stored calcium ion (Ca2+);   release of sequestered calcium ion (Ca2+);   release of sequestered calcium ion into cytoplasm;   release of stored calcium ion (Ca2+);   release of stored calcium ion (Ca2+) into cytoplasm


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release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 BCL2 binding component 3 involved_in ISO (PMID:17024184) UniProt PMID:17024184 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:14592837) BHF-UCL PMID:14592837 NCBI chrNW_004936524:2,765,271...2,767,259 JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:14592837) BHF-UCL PMID:14592837 NCBI chrNW_004936524:2,787,963...2,789,116 JBrowse link
G Ddit3 DNA damage inducible transcript 3 involved_in ISO (MGI:4366390|PMID:19752026) UniProt PMID:19752026 MGI:4366390 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO PMID:8371717 BHF-UCL PMID:8371717 RGD:8554702 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in ISO (MGI:4366390|PMID:19752026) UniProt PMID:19752026 MGI:4366390 NCBI chrNW_004936697:2,154,517...2,199,913 JBrowse link
G F2r coagulation factor II thrombin receptor ISO RGD PMID:15145074 RGD:1582290 NCBI chrNW_004936549:226,508...247,024 JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A acts_upstream_of_or_within ISO (MGI:2665228|PMID:12704193)
(MGI:3513875|PMID:15289441)
MGI PMID:12704193 PMID:15289441 MGI:2665228 MGI:3513875 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B acts_upstream_of_or_within ISO (MGI:3615100|PMID:15024040) MGI PMID:15024040 MGI:3615100 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Glp1r glucagon like peptide 1 receptor ISO RGD PMID:15789279 RGD:1598438 NCBI chrNW_004936476:20,541,812...20,580,454 JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:1939645) ComplexPortal PMID:1939645 NCBI chrNW_004936677:2,774,076...2,779,660 JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (PMID:1939645) ComplexPortal PMID:1939645 NCBI chrNW_004936619:3,627,649...3,629,129 JBrowse link
G Gp5 glycoprotein V platelet involved_in ISO (PMID:1939645) ComplexPortal PMID:1939645 NCBI chrNW_004936711:403,876...405,570 JBrowse link
G Gp9 glycoprotein IX platelet involved_in ISO (PMID:1939645) ComplexPortal PMID:1939645 NCBI chrNW_004936798:170,654...171,625 JBrowse link
G Hcrt hypocretin neuropeptide precursor NOT ISO cortical neurons RGD PMID:15858425 RGD:1600997 NCBI chrNW_004936490:17,007,001...17,008,363 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in ISO (PMID:15862800)
(PMID:18703043)
UniProt PMID:15862800 PMID:18703043 NCBI chrNW_004936565:335,238...394,683 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO (PMID:18566482), (PMID:18703043), (PMID:8882600)
(PMID:15862800)
UniProt PMID:8882600 PMID:15862800 PMID:18566482 PMID:18703043 NCBI chrNW_004936525:5,711,894...5,729,074 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in ISO (PMID:18703043) UniProt PMID:18703043 NCBI chrNW_004936499:1,002,083...1,109,446 JBrowse link
G Ibtk inhibitor of Bruton tyrosine kinase acts_upstream_of_or_within ISO (PMID:11577348) MGI PMID:11577348 NCBI chrNW_004936510:8,345,182...8,425,080 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 involved_in ISO PMID:16223735
(MGI:4366390|PMID:19752026)
BHF-UCL
UniProt
PMID:16223735 PMID:19752026 MGI:4366390 RGD:8554324 NCBI chrNW_004936577:3,896,455...4,198,396 JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor type 2 involved_in ISO PMID:23166348 BHF-UCL PMID:23166348 RGD:12790654 NCBI chrNW_004936548:646,019...1,120,426 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3687439|PMID:1505025) UniProt PMID:1505025 MGI:3687439 NCBI chrNW_004936474:15,293,115...15,314,072 JBrowse link
G LOC101970885 lymphotactin involved_in
acts_upstream_of_or_within
ISO (MGI:77040|PMID:7973732)
(MGI:1344950|PMID:10518929)
BHF-UCL
MGI
PMID:7973732 PMID:10518929 MGI:1344950 MGI:77040 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G LOC101973366 calcium homeostasis endoplasmic reticulum protein involved_in ISO (PMID:12656674) UniProt PMID:12656674 NCBI chrNW_004936596:4,084,091...4,102,096 JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 ISO RGD PMID:17613490 RGD:7205504 NCBI chrNW_004936588:4,600,344...4,608,793 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3772417|PMID:18082965) MGI PMID:18082965 MGI:3772417 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in
acts_upstream_of_or_within
ISO (PMID:11854751)
(MGI:5315687|PMID:19265036)
(MGI:3708075|PMID:17404231)
(PMID:19265036)
BHF-UCL
MGI
PMID:11854751 PMID:17404231 PMID:19265036 MGI:3708075 MGI:5315687 NCBI chrNW_004936905:76,781...128,995 JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:11606584)
(MGI:1861532|PMID:10925250)
UniProt PMID:10925250 PMID:11606584 MGI:1861532 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:1345540|PMID:10508267) UniProt PMID:10508267 MGI:1345540 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Ryr1 ryanodine receptor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:11741831), (PMID:16163667)
(MGI:2665228|PMID:12704193)
PMID:19116207
UniProt
MGI
BHF-UCL
PMID:11741831 PMID:12704193 PMID:16163667 PMID:19116207 MGI:2665228 RGD:7242196 NCBI chrNW_004936801:1,185,615...1,298,416 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:12443530), (PMID:17921453) BHF-UCL PMID:12443530 PMID:17921453 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (MGI:3850579|PMID:19515693) MGI PMID:19515693 MGI:3850579 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (MGI:5285159|PMID:20495006), (MGI:5691857|PMID:25144390) UniProt PMID:20495006 PMID:25144390 MGI:5285159 MGI:5691857 NCBI chrNW_004936599:1,301,937...1,343,046 JBrowse link
G Trpm2 transient receptor potential cation channel subfamily M member 2 involved_in ISO (PMID:27068538)
(MGI:5298324|PMID:21753080)
UniProt PMID:21753080 PMID:27068538 MGI:5298324 NCBI chrNW_004936500:21,960...76,895 JBrowse link
G Xcr1 X-C motif chemokine receptor 1 acts_upstream_of_or_within ISO (MGI:1344950|PMID:10518929) MGI PMID:10518929 MGI:1344950 NCBI chrNW_004936596:93,433...94,480 JBrowse link
calcium export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 involved_in ISO (PMID:19797662)
(MGI:5897526|PMID:27669901)
UniProt PMID:19797662 PMID:27669901 MGI:5897526 NCBI chrNW_004936477:21,550,104...21,589,662 JBrowse link
G Slc8b1 solute carrier family 8 member B1 involved_in ISO (PMID:24898248)
(MGI:5902676|PMID:24067497), (MGI:5902863|PMID:28445457)
UniProt PMID:24067497 PMID:24898248 PMID:28445457 MGI:5902676 MGI:5902863 NCBI chrNW_004936668:3,160,148...3,181,814 JBrowse link
negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G LOC101962457 triadin ISO RGD PMID:16176928 RGD:7327230 NCBI chrNW_004936802:389,653...637,372 JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:12084713 RGD:727385 NCBI chrNW_004936514:10,240,990...10,272,859 JBrowse link
G Prkce protein kinase C epsilon involved_in ISO PMID:20383739 UniProt PMID:20383739 RGD:7206836 NCBI chrNW_004936508:6,018,374...6,495,216 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO RGD PMID:12876066 RGD:731229 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO RGD PMID:12876066 RGD:731229 NCBI chrNW_004936628:310,720...394,002 JBrowse link
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO (PMID:26164367) UniProt PMID:26164367 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:26164367) UniProt PMID:26164367 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:26164367) UniProt PMID:26164367 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (PMID:16601229)
PMID:17569730
(PMID:15041652)
BHF-UCL PMID:15041652 PMID:16601229 PMID:17569730 RGD:2314601 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Clic2 chloride intracellular channel 2 involved_in ISO (PMID:15147738), (PMID:15916532) BHF-UCL PMID:15147738 PMID:15916532 NCBI chrNW_004936927:514,989...543,691 JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A NOT|involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:12443530) BHF-UCL PMID:12443530 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel acts_upstream_of_or_within ISO (MGI:3708075|PMID:17404231) MGI PMID:17404231 MGI:3708075 NCBI chrNW_004936905:76,781...128,995 JBrowse link
G Sri sorcin involved_in ISO (PMID:17699613) BHF-UCL PMID:17699613 NCBI chrNW_004936763:715,884...728,548 JBrowse link
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin associated protein 1 involved_in ISO PMID:12873381
(MGI:3603715|PMID:15379999)
UniProt PMID:12873381 PMID:15379999 MGI:3603715 RGD:6482800 NCBI chrNW_004936490:16,645,116...16,652,310 JBrowse link
G LOC101966195 huntingtin involved_in ISO (PMID:12873381) UniProt PMID:12873381 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO PMID:17410128 ARUK-UCL PMID:17410128 RGD:13673830 NCBI chrNW_004936498:2,468,020...2,501,344 JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16223735) BHF-UCL PMID:16223735 NCBI chrNW_004936905:76,781...128,995 JBrowse link
positive regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3839222|PMID:19228876) MGI PMID:19228876 MGI:3839222 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in ISO PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Aplnr apelin receptor involved_in ISO (PMID:25639753) UniProt PMID:25639753 NCBI chrNW_004936581:5,230,836...5,234,562 JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:3694443|PMID:15947791) MGI PMID:15947791 MGI:3694443 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bdkrb1 bradykinin receptor B1 NOT ISO in nociceptive dorsal root ganglion neurons
in urinary bladder urothelium
RGD PMID:15319421 PMID:15576455 RGD:1625040 RGD:1625754 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G Capn3 calpain 3 involved_in ISO (MGI:3811664|PMID:18676612) UniProt PMID:18676612 MGI:3811664 NCBI chrNW_004936471:5,667,839...5,711,822 JBrowse link
G Casq1 calsequestrin 1 involved_in ISO (PMID:28895244) UniProt PMID:28895244 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16672701)
(MGI:1100180|PMID:9382888)
(MGI:3839222|PMID:19228876)
(PMID:9382888)
UniProt
MGI
PMID:9382888 PMID:16672701 PMID:19228876 MGI:1100180 MGI:3839222 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO (PMID:10415068), (PMID:10869418) ARUK-UCL PMID:10415068 PMID:10869418 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO (PMID:12782716) UniProt PMID:12782716 NCBI chrNW_004936676:60,869...63,028 JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12782716) UniProt PMID:12782716 NCBI chrNW_004936676:72,383...73,697 JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12782716) UniProt PMID:12782716 NCBI chrNW_004936676:33,580...40,323 JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 involved_in ISO (PMID:12782716) UniProt PMID:12782716 NCBI chrNW_004936762:66,636...69,694 JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:9804683 RGD:2316286 NCBI chrNW_004936469:50,981,198...50,986,224 JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO (PMID:1282671), (PMID:7838121) BHF-UCL PMID:1282671 PMID:7838121 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:12628492 RGD:728499 NCBI chrNW_004936535:1,950,117...2,005,786 JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO (PMID:1672265), (PMID:19052258) BHF-UCL PMID:1672265 PMID:19052258 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G F2r coagulation factor II thrombin receptor involved_in ISO (PMID:1672265) BHF-UCL PMID:1672265 NCBI chrNW_004936549:226,508...247,024 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:15705806) UniProt PMID:15705806 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (MGI:5707553|PMID:26375174)
(MGI:5464224|PMID:23133519)
MGI PMID:23133519 PMID:26375174 MGI:5464224 MGI:5707553 NCBI chrNW_004936469:55,973,001...55,974,070 JBrowse link
G Il13 interleukin 13 ISO RGD PMID:20045483 RGD:4145470 NCBI chrNW_004936647:2,529,933...2,532,503 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:8187959 RGD:2292619 NCBI chrNW_004936508:3,928,467...3,983,481 JBrowse link
G LOC101956523 cell migration inducing hyaluronidase 1 involved_in ISO (PMID:23990668) UniProt PMID:23990668 NCBI chrNW_004936483:19,721,256...19,799,371 JBrowse link
G LOC101962457 triadin ISO RGD PMID:21811790 RGD:7327228 NCBI chrNW_004936802:389,653...637,372 JBrowse link
G LOC101970885 lymphotactin involved_in ISO (PMID:7602097) BHF-UCL PMID:7602097 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G Npsr1 neuropeptide S receptor 1 involved_in ISO (PMID:16790440) UniProt PMID:16790440 NCBI chrNW_004936478:10,352,894...10,542,949 JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:10799761 RGD:9743926 NCBI chrNW_004936514:10,240,990...10,272,859 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:22454520) BHF-UCL PMID:22454520 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Plcg1 phospholipase C gamma 1 involved_in ISO (PMID:22454520) BHF-UCL PMID:22454520 NCBI chrNW_004936561:598,372...631,575 JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:15641770) UniProt PMID:15641770 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) BHF-UCL PMID:22338092 MGI:5487506 NCBI chrNW_004936763:715,884...728,548 JBrowse link
G Tex101 testis expressed 101 ISO RGD PMID:11809740 RGD:634491 NCBI chrNW_004936706:649,463...690,995 JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO PMID:2873512 UniProt PMID:2873512 RGD:8554039 NCBI chrNW_004936542:4,323,905...4,329,940 JBrowse link
G Trpc1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:19052258) BHF-UCL PMID:19052258 NCBI chrNW_004936540:4,340,672...4,417,655 JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 involved_in ISO PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Calm1 calmodulin 1 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Jph2 junctophilin 2 involved_in ISO (PMID:20095964) UniProt PMID:20095964 NCBI chrNW_004936530:2,570,365...2,606,743 JBrowse link
G LOC101962457 triadin involved_in ISO (PMID:15041652), (PMID:15731460) BHF-UCL PMID:15041652 PMID:15731460 NCBI chrNW_004936802:389,653...637,372 JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17178715)
(MGI:5427070|PMID:21859974), (MGI:5430893|PMID:17178715)
BHF-UCL PMID:17178715 PMID:21859974 MGI:5427070 MGI:5430893 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Casq2 calsequestrin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:16601229), (PMID:16908766)
(MGI:3689635|PMID:16932808)
(MGI:1202079|PMID:9525981)
PMID:17569730
BHF-UCL
UniProt
MGI
PMID:9525981 PMID:16601229 PMID:16908766 PMID:16932808 PMID:17569730 MGI:1202079 MGI:3689635 RGD:2314601 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Dmd dystrophin involved_in ISO (MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:4420848 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO (MGI:82999|PMID:8831698) MGI PMID:8831698 MGI:82999 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Tmem38a transmembrane protein 38A acts_upstream_of_or_within ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936596:3,965,220...3,984,120 JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate beta-hydroxylase involved_in ISO (PMID:21062895) UniProt PMID:21062895 NCBI chrNW_004936496:11,604,992...11,815,680 JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO (MGI:3621681|PMID:11086997) MGI PMID:11086997 MGI:3621681 NCBI chrNW_004936471:14,105,832...14,257,386 JBrowse link
regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:17242276) BHF-UCL PMID:17242276 NCBI chrNW_004936563:3,520,195...4,170,716 JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chrNW_004936564:2,759,085...2,885,394 JBrowse link
G Coro1a coronin 1A acts_upstream_of_or_within ISO (MGI:5559799|PMID:24270184) MGI PMID:24270184 MGI:5559799 NCBI chrNW_004936501:12,338,542...12,344,236 JBrowse link
G Diaph1 diaphanous related formin 1 involved_in ISO (PMID:15123714) BHF-UCL PMID:15123714 NCBI chrNW_004936504:12,548,452...12,645,236 JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:7689577 RGD:8693381 NCBI chrNW_004936541:2,822,789...2,871,069 JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:3769059 NCBI chrNW_004936514:10,980,136...10,983,323 JBrowse link
G LOC101967032 cytochrome b-245 light chain acts_upstream_of_or_within ISO (MGI:5548044|PMID:24185898) MGI PMID:24185898 MGI:5548044 NCBI chrNW_004936641:1,036,967...1,044,954 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253) RGD
MGI
PMID:16177098 PMID:23509253 MGI:5471851 RGD:1578516 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004936581:2,743,133...2,751,925 JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within ISO (MGI:5559803|PMID:24265601) MGI PMID:24265601 MGI:5559803 NCBI chrNW_004936627:635,784...641,290 JBrowse link
G Prkce protein kinase C epsilon acts_upstream_of_or_within ISO (MGI:5475040|PMID:23479225)
(MGI:3580969|PMID:15905535)
MGI PMID:15905535 PMID:23479225 MGI:3580969 MGI:5475040 NCBI chrNW_004936508:6,018,374...6,495,216 JBrowse link
G Prkd1 protein kinase D1 acts_upstream_of_or_within ISO (MGI:5475040|PMID:23479225) MGI PMID:23479225 MGI:5475040 NCBI chrNW_004936494:4,469,092...4,601,183 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO (MGI:3583523|PMID:12960403) UniProt PMID:12960403 MGI:3583523 NCBI chrNW_004936675:216,970...325,670 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253) MGI PMID:23509253 MGI:5471851 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) MGI PMID:20585042 MGI:4838721 NCBI chrNW_004936542:7,225,387...7,370,163 JBrowse link
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta involved_in ISO PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Casq1 calsequestrin 1 acts_upstream_of_or_within ISO (MGI:2449410|PMID:12419813)
(MGI:3814667|PMID:17627988)
MGI PMID:12419813 PMID:17627988 MGI:2449410 MGI:3814667 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (PMID:15041652)
(MGI:3689635|PMID:16932808)
BHF-UCL
UniProt
PMID:15041652 PMID:16932808 MGI:3689635 NCBI chrNW_004936627:1,001,681...1,069,377 JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 acts_upstream_of_or_within ISO (MGI:5694290|PMID:26102480) MGI PMID:26102480 MGI:5694290 NCBI chrNW_004936496:12,381,225...12,505,121 JBrowse link
G Clic2 chloride intracellular channel 2 involved_in ISO (PMID:15147738), (PMID:15916532) BHF-UCL PMID:15147738 PMID:15916532 NCBI chrNW_004936927:514,989...543,691 JBrowse link
G Dhrs7c dehydrogenase/reductase 7C acts_upstream_of_or_within ISO (MGI:5306721|PMID:21995425) MGI PMID:21995425 MGI:5306721 NCBI chrNW_004936595:2,732,106...2,769,782 JBrowse link
G Dmd dystrophin involved_in ISO (MGI:4420848|PMID:20080623), (MGI:5487906|PMID:23263329) BHF-UCL PMID:20080623 PMID:23263329 MGI:4420848 MGI:5487906 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in
acts_upstream_of_or_within
ISO (PMID:20431056)
(MGI:3028710|PMID:14592808), (MGI:5007884|PMID:19578067)
(MGI:3639647|PMID:16672364)
BHF-UCL
MGI
PMID:14592808 PMID:16672364 PMID:19578067 PMID:20431056 MGI:3028710 MGI:3639647 MGI:5007884 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chrNW_004936664:3,088,072...3,092,034 JBrowse link
G LOC101962457 triadin involved_in ISO (PMID:15041652) RGD
BHF-UCL
PMID:15041652 PMID:17569730 RGD:2314601 NCBI chrNW_004936802:389,653...637,372 JBrowse link
G Mettl21c methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within ISO (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chrNW_004936472:8,355,075...8,366,229 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO PMID:23382383 UniProt PMID:23382383 RGD:10047354 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO (MGI:3655341|PMID:9118481) MGI PMID:9118481 MGI:3655341 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO (PMID:22067155) RGD
UniProt
PMID:15628869 PMID:22067155 RGD:7241270 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:22067155) RGD
UniProt
PMID:15628869 PMID:22067155 RGD:7241270 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:22067155) RGD
UniProt
PMID:15628869 PMID:22067155 RGD:7241270 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Dmd dystrophin involved_in ISO (MGI:4420848|PMID:20080623) BHF-UCL PMID:20080623 MGI:4420848 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869)
(MGI:1195585|PMID:9461216)
BHF-UCL PMID:7592869 PMID:9461216 MGI:1195585 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in
NOT|involved_in
ISO (PMID:7592869)
(MGI:3621834|PMID:12837242)
(MGI:3836106|PMID:17921453)
(PMID:17921453)
(PMID:20431056)
BHF-UCL PMID:7592869 PMID:12837242 PMID:17921453 PMID:20431056 MGI:3621834 MGI:3836106 NCBI chrNW_004936493:7,916,002...7,922,747 JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO (PMID:24125847) BHF-UCL PMID:24125847 NCBI chrNW_004936664:3,088,072...3,092,034 JBrowse link
G Jph3 junctophilin 3 involved_in ISO (MGI:3654871|PMID:16809425) UniProt PMID:16809425 MGI:3654871 NCBI chrNW_004936641:1,619,640...1,668,480 JBrowse link
G Jsrp1 junctional sarcoplasmic reticulum protein 1 acts_upstream_of_or_within ISO (MGI:3625379|PMID:16638807) MGI PMID:16638807 MGI:3625379 NCBI chrNW_004936588:1,345,880...1,349,583 JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chrNW_004936480:8,123,437...9,235,586 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO (MGI:1352171|PMID:10603936) MGI PMID:10603936 MGI:1352171 NCBI chrNW_004936658:1,443,626...1,453,770 JBrowse link
G Selenon selenoprotein N involved_in ISO (PMID:18713863) UniProt PMID:18713863 NCBI chrNW_004936474:10,381,646...10,396,638 JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casq1 calsequestrin 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5306707|PMID:22049211)
(MGI:3814667|PMID:17627988)
UniProt
MGI
PMID:17627988 PMID:22049211 MGI:3814667 MGI:5306707 NCBI chrNW_004936740:430,367...442,468 JBrowse link
G Dmd dystrophin involved_in ISO (MGI:3837615|PMID:19198614) BHF-UCL PMID:19198614 MGI:3837615 NCBI chrNW_004936553:7,157,526...7,943,703 JBrowse link
release of sequestered calcium ion into cytosol by endoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faslg Fas ligand acts_upstream_of_or_within ISO (PMID:26582200) MGI PMID:26582200 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (MGI:6141091|PMID:27188440) MGI PMID:27188440 MGI:6141091 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101962457 triadin acts_upstream_of_or_within ISO (MGI:3849347|PMID:19383796) MGI PMID:19383796 MGI:3849347 NCBI chrNW_004936802:389,653...637,372 JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:15509781) UniProt PMID:15509781 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISO PMID:11316255
(MGI:3764002|PMID:18003898)
UniProt PMID:11316255 PMID:18003898 MGI:3764002 RGD:12903237 NCBI chrNW_004936801:1,185,615...1,298,416 JBrowse link
G Ryr2 ryanodine receptor 2 involved_in
acts_upstream_of_or_within
ISO (PMID:12919952)
(MGI:4442115|PMID:20226167)
(MGI:2182484|PMID:12089338)
BHF-UCL
MGI
PMID:12089338 PMID:12919952 PMID:20226167 MGI:2182484 MGI:4442115 NCBI chrNW_004936484:15,402,488...15,825,410 JBrowse link
G Tmem38a transmembrane protein 38A acts_upstream_of_or_within ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936596:3,965,220...3,984,120 JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (MGI:3715564|PMID:17611541) MGI PMID:17611541 MGI:3715564 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12295
    cellular process 11513
      negative regulation of cellular process 4321
        negative regulation of sequestering of calcium ion 113
          release of sequestered calcium ion into cytosol 113
            calcium export from the mitochondrion + 2
            negative regulation of release of sequestered calcium ion into cytosol + 15
            positive regulation of release of sequestered calcium ion into cytosol + 43
            regulation of release of sequestered calcium ion into cytosol + 82
            release of sequestered calcium ion into cytosol by Golgi + 0
            release of sequestered calcium ion into cytosol by endoplasmic reticulum + 25
            release of sequestered calcium ion into postsynaptic cytosol 0
            release of sequestered calcium ion into presynaptic cytosol 0
Path 2
Term Annotations click to browse term
  biological_process 12295
    biological regulation 9032
      regulation of biological quality 3379
        homeostatic process 1714
          chemical homeostasis 1123
            ion homeostasis 702
              cation homeostasis 648
                cellular cation homeostasis 563
                  cellular divalent inorganic cation homeostasis 432
                    cellular calcium ion homeostasis 411
                      regulation of cytosolic calcium ion concentration 318
                        positive regulation of cytosolic calcium ion concentration 280
                          calcium ion transport into cytosol 163
                            calcium ion transmembrane import into cytosol 139
                              release of sequestered calcium ion into cytosol 113
                                calcium export from the mitochondrion + 2
                                negative regulation of release of sequestered calcium ion into cytosol + 15
                                positive regulation of release of sequestered calcium ion into cytosol + 43
                                regulation of release of sequestered calcium ion into cytosol + 82
                                release of sequestered calcium ion into cytosol by Golgi + 0
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum + 25
                                release of sequestered calcium ion into postsynaptic cytosol 0
                                release of sequestered calcium ion into presynaptic cytosol 0
paths to the root