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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of striated muscle cell differentiation
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Accession:GO:0051154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms:exact_synonym: down regulation of striated muscle cell differentiation;   downregulation of striated muscle cell differentiation
 narrow_synonym: inhibition of striated muscle cell differentiation


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negative regulation of striated muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:15520282) RGD PMID:15520282 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:99146 (PMID:20004191) RGD PMID:20004191 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Ybx1 Y box binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20004191)		 Ensembl
RGD		 PMID:20004191 GO_REF:0000107 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862 		JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
ISS		 (PMID:18545679)
GO_REF:0000024		 RGD
UniProt		 PMID:18545679 GO_REF:0000024 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Ccnd2 cyclin D2 IDA RGD PMID:27302109 RGD:151660350 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5902683|PMID:18371447)		 Ensembl
RGD		 PMID:18371447 GO_REF:0000107 MGI:5902683 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in ISO UniProtKB:O75084 (PMID:23939491) RGD PMID:23939491 NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO UniProtKB:Q8WU20 (PMID:23939491) RGD PMID:23939491 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
G Hdac3 histone deacetylase 3 acts_upstream_of_or_within ISO (PMID:24565863) RGD PMID:24565863 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IEA		 (PMID:20081117)
GO_REF:0000107		 RGD
Ensembl		 PMID:20081117 GO_REF:0000107 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3689643|PMID:16151019)		 Ensembl
RGD		 PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP RGD PMID:19358331 RGD:2312604 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457 		JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IEA		 (MGI:4829580|PMID:20516643)
GO_REF:0000107		 RGD
Ensembl		 PMID:20516643 GO_REF:0000107 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (PMID:17909105) RGD PMID:17909105 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (PMID:29065170) RGD PMID:29065170 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242 		JBrowse link
negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940), (PMID:23824195) RGD PMID:18302940 PMID:23824195 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in IMP PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5607242|PMID:17612490)		 UniProt
RGD		 PMID:17612490 GO_REF:0000024 MGI:5607242 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 involved_in ISO
IEA		 (MGI:5297791|PMID:12657651)
GO_REF:0000107		 RGD
Ensembl		 PMID:12657651 GO_REF:0000107 MGI:5297791 NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12050162)		 UniProt
RGD		 PMID:12050162 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:7737360 RGD:151665771 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Daxx death-domain associated protein IDA RGD PMID:19308989 RGD:9587764 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Hdac1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac5 histone deacetylase 5 involved_in ISO (PMID:10983972), (PMID:11081517) RGD PMID:10983972 PMID:11081517 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3849559 (PMID:17940050)		 Ensembl
RGD		 PMID:17940050 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in ISO
IEA		 (PMID:15653675)
GO_REF:0000107		 RGD
Ensembl		 PMID:15653675 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:5319604|PMID:18299578) RGD PMID:18299578 MGI:5319604 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Plpp7 phospholipid phosphatase 7 (inactive) acts_upstream_of_or_within ISO MGI:1928394 (PMID:19704009) RGD PMID:19704009 NCBI chr 3:15,384,461...15,398,820
Ensembl chr 3:15,384,492...15,398,883 		JBrowse link
G Rpl3l ribosomal protein L3-like involved_in ISO (MGI:6838892|PMID:26684695) RGD PMID:26684695 MGI:6838892 NCBI chr10:13,753,914...13,764,458
Ensembl chr10:13,753,886...13,764,457 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:6294241|PMID:22579779) RGD PMID:22579779 MGI:6294241 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
G Trim72 tripartite motif containing 72 acts_upstream_of_or_within ISO (PMID:23965929) RGD PMID:23965929 NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) RGD PMID:17612490 MGI:5607242 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    negative regulation of biological process 5811
      negative regulation of developmental process 1107
        negative regulation of cell differentiation 798
          negative regulation of muscle cell differentiation 78
            negative regulation of striated muscle cell differentiation 46
              negative regulation of cardiac muscle cell differentiation + 9
              negative regulation of cardiac muscle fiber development 0
              negative regulation of cell growth involved in cardiac muscle cell development 16
              negative regulation of myotube differentiation + 19
              negative regulation of skeletal muscle fiber development 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    developmental process 7009
      cellular developmental process 4729
        cell differentiation 4728
          muscle cell differentiation 484
            regulation of muscle cell differentiation 179
              regulation of striated muscle cell differentiation 115
                negative regulation of striated muscle cell differentiation 46
                  negative regulation of cardiac muscle cell differentiation + 9
                  negative regulation of cardiac muscle fiber development 0
                  negative regulation of cell growth involved in cardiac muscle cell development 16
                  negative regulation of myotube differentiation + 19
                  negative regulation of skeletal muscle fiber development 0
paths to the root