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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of striated muscle cell differentiation
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Accession:GO:0051154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms:exact_synonym: down regulation of striated muscle cell differentiation;   downregulation of striated muscle cell differentiation
 narrow_synonym: inhibition of striated muscle cell differentiation


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negative regulation of striated muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15520282) Ensembl
MGI		 PMID:15520282 GO_REF:0000107 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20004191) Ensembl
MGI		 PMID:20004191 GO_REF:0000107 NCBI chr 8:5,628,381...5,632,375
Ensembl chr 8:5,628,380...5,632,607 		JBrowse link
G YBX1 Y-box binding protein 1 acts_upstream_of_or_within ISO (PMID:20004191) MGI PMID:20004191 NCBI chr 6:168,716,782...168,736,475
Ensembl chr 6:168,716,774...168,736,604 		JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:27302109 RGD:151660350 NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,288 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,358...211,346 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,725,432...33,852,952
Ensembl chr 5:33,725,444...33,849,953 		JBrowse link
G FZD7 frizzled class receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:105,644,164...105,648,860
Ensembl chr15:105,644,188...105,648,850 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24565863) Ensembl
MGI		 PMID:24565863 GO_REF:0000107 NCBI chr 2:143,273,188...143,287,421
Ensembl chr 2:143,273,192...143,287,399 		JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:42,447,391...43,068,824
Ensembl chr 2:42,453,681...43,068,325 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO RGD PMID:19358331 RGD:2312604 NCBI chr12:33,396,473...33,410,395
Ensembl chr12:33,396,473...33,411,440 		JBrowse link
G CAV3 caveolin 3 ISO RGD PMID:21170593 RGD:6784534 NCBI chr13:65,117,868...65,130,886
Ensembl chr13:65,117,795...65,131,273 		JBrowse link
G CTDP1 CTD phosphatase subunit 1 ISO RGD PMID:22569295 RGD:9686371 NCBI chr 1:145,769,763...145,811,673
Ensembl chr 1:145,769,771...145,811,678 		JBrowse link
G FOXP1 forkhead box P1 ISO RGD PMID:26333362 RGD:11561912 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24190878 RGD:10449133 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,690,319...49,700,735
Ensembl chr 6:49,690,370...49,701,189 		JBrowse link
G MIR451 microRNA mir-451 ISO RGD PMID:25209900 RGD:11558015 NCBI chr12:45,088,808...45,088,872
Ensembl chr12:45,088,808...45,088,872 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:22082674 RGD:11533929 NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,095...12,020,415 		JBrowse link
G PI16 peptidase inhibitor 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17909105) Ensembl
MGI		 PMID:17909105 GO_REF:0000107 NCBI chr 7:32,600,952...32,613,505
Ensembl chr 7:32,600,770...32,614,924 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO RGD PMID:22198280 RGD:5687133 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G RBM10 RNA binding motif protein 10 ISO RGD PMID:30257214 RGD:151667449 NCBI chr  X:41,773,232...41,803,656
Ensembl chr  X:41,773,232...41,803,653 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:16380388 RGD:13524577 NCBI chr10:936,836...940,083
Ensembl chr10:936,789...940,098 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9918533 RGD:7207376 NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,383,345...87,390,893 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 ISO RGD PMID:25022898 RGD:13464131 NCBI chr13:158,577,026...158,629,878
Ensembl chr13:158,577,379...158,628,262 		JBrowse link
G YY1 YY1 transcription factor ISO RGD PMID:18632988 RGD:9588273 NCBI chr 7:121,132,168...121,170,699
Ensembl chr 7:121,132,191...121,170,697 		JBrowse link
G ZNF416 zinc finger protein 416 acts_upstream_of_or_within ISO (PMID:29065170) MGI PMID:29065170 NCBI chr 6:62,039,477...62,043,177 JBrowse link
negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor involved_in ISO PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,410,467...5,414,074
Ensembl chr 3:5,410,518...5,414,072 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:47,687,662...47,692,761
Ensembl chr 5:47,686,404...47,692,762 		JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,505,698...19,514,481
Ensembl chr 4:19,505,701...19,514,406 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:7737360 RGD:151665771 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:19308989 RGD:9587764 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110 		JBrowse link
G HDAC1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411 		JBrowse link
G HDAC3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:143,273,188...143,287,421
Ensembl chr 2:143,273,192...143,287,399 		JBrowse link
G HDAC4 histone deacetylase 4 involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr15:138,378,237...138,657,266
Ensembl chr15:138,381,635...138,614,301 		JBrowse link
G HDAC5 histone deacetylase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:19,077,910...19,119,463
Ensembl chr12:19,078,005...19,121,154 		JBrowse link
G MYOCD myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17940050) Ensembl
MGI		 PMID:17940050 GO_REF:0000107 NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,258 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:51,086,014...51,089,165
Ensembl chr16:51,086,011...51,089,162 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G PLPP7 phospholipid phosphatase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19704009) Ensembl
MGI		 PMID:19704009 GO_REF:0000107 NCBI chr 1:271,268,843...271,283,657
Ensembl chr 1:271,268,870...271,283,655 		JBrowse link
G RPL3L ribosomal protein L3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,004,907...40,016,702
Ensembl chr 3:40,007,868...40,016,699 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in ISO (MGI:6294241|PMID:22579779) ARUK-UCL PMID:22579779 MGI:6294241 NCBI chr14:42,190,958...42,197,384 JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr 3:17,286,471...17,297,841
Ensembl chr 3:17,284,431...17,306,738 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) UniProt PMID:17612490 MGI:5607242 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17634
    negative regulation of biological process 5585
      negative regulation of developmental process 1042
        negative regulation of cell differentiation 750
          negative regulation of muscle cell differentiation 77
            negative regulation of striated muscle cell differentiation 45
              negative regulation of cardiac muscle cell differentiation + 9
              negative regulation of cardiac muscle fiber development 0
              negative regulation of cell growth involved in cardiac muscle cell development 16
              negative regulation of myotube differentiation + 18
              negative regulation of skeletal muscle fiber development 0
Path 2
Term Annotations click to browse term
  biological_process 17634
    developmental process 6634
      cellular developmental process 4461
        cell differentiation 4460
          muscle cell differentiation 470
            regulation of muscle cell differentiation 173
              regulation of striated muscle cell differentiation 112
                negative regulation of striated muscle cell differentiation 45
                  negative regulation of cardiac muscle cell differentiation + 9
                  negative regulation of cardiac muscle fiber development 0
                  negative regulation of cell growth involved in cardiac muscle cell development 16
                  negative regulation of myotube differentiation + 18
                  negative regulation of skeletal muscle fiber development 0
paths to the root