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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of striated muscle cell differentiation
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Accession:GO:0051154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms:exact_synonym: down regulation of striated muscle cell differentiation;   downregulation of striated muscle cell differentiation
 narrow_synonym: inhibition of striated muscle cell differentiation


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negative regulation of striated muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15520282) Ensembl
MGI		 PMID:15520282 GO_REF:0000107 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20004191) Ensembl
MGI		 PMID:20004191 GO_REF:0000107 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936 		JBrowse link
G YBX1 Y-box binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20004191) Ensembl
MGI		 PMID:20004191 GO_REF:0000107 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805 		JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IDA (PMID:18545679) BHF-UCL PMID:18545679 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:27302109 RGD:151660350 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 involved_in IGI (PMID:23939491) BHF-UCL PMID:23939491 NCBI chr12:69,470,388...69,579,793
Ensembl chr12:69,470,349...69,579,793 		JBrowse link
G FZD7 frizzled class receptor 7 involved_in IGI (PMID:23939491) BHF-UCL PMID:23939491 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24565863) Ensembl
MGI		 PMID:24565863 GO_REF:0000107 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849 		JBrowse link
G MIR200B microRNA 200b involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR222 microRNA 222 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR590 microRNA 590 involved_in IDA (PMID:25163461) BHF-UCL PMID:25163461 NCBI chr 7:74,191,198...74,191,294
Ensembl chr 7:74,191,198...74,191,294 		JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IMP (PMID:20081117) BHF-UCL PMID:20081117 NCBI chr11:15,966,449...16,738,477
Ensembl chr11:15,966,449...16,739,591 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD4 SMAD family member 4 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO RGD PMID:19358331 RGD:2312604 NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346 		JBrowse link
G CAV3 caveolin 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21170593 GO_REF:0000107 RGD:6784534 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808 		JBrowse link
G CTDP1 CTD phosphatase subunit 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22569295 GO_REF:0000107 RGD:9686371 NCBI chr18:79,676,768...79,756,625
Ensembl chr18:79,679,803...79,754,503 		JBrowse link
G FOXP1 forkhead box P1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:26333362 GO_REF:0000107 RGD:11561912 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:24190878 GO_REF:0000107 RGD:10449133 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G MIR199A1 microRNA 199a-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:10,817,426...10,817,496
Ensembl chr19:10,817,426...10,817,496 		JBrowse link
G MIR199A2 microRNA 199a-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:172,144,535...172,144,644
Ensembl chr 1:172,144,535...172,144,644 		JBrowse link
G MIR199B microRNA 199b involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 9:128,244,721...128,244,830
Ensembl chr 9:128,244,721...128,244,830 		JBrowse link
G MIR451A microRNA 451a ISO RGD PMID:25209900 RGD:11558015 NCBI chr17:28,861,369...28,861,440
Ensembl chr17:28,861,369...28,861,440 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:22082674 RGD:11533929 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PI16 peptidase inhibitor 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17909105) Ensembl
MGI		 PMID:17909105 GO_REF:0000107 NCBI chr 6:36,948,296...36,964,837
Ensembl chr 6:36,948,263...36,964,837 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:22198280 GO_REF:0000107 RGD:5687133 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G RBM10 RNA binding motif protein 10 ISO RGD PMID:30257214 RGD:151667449 NCBI chr  X:47,145,221...47,186,813
Ensembl chr  X:47,145,221...47,186,813 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16380388 GO_REF:0000107 RGD:13524577 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RGS4 regulator of G protein signaling 4 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9918533 GO_REF:0000107 RGD:7207376 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25022898 GO_REF:0000107 RGD:13464131 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
G YY1 YY1 transcription factor involved_in ISO
IEA		 RGD
Ensembl		 PMID:18632988 GO_REF:0000107 RGD:9588273 NCBI chr14:100,239,144...100,282,788
Ensembl chr14:100,238,298...100,282,788 		JBrowse link
G ZNF416 zinc finger protein 416 acts_upstream_of_or_within ISO (PMID:29065170) MGI PMID:29065170 NCBI chr19:57,571,566...57,578,911
Ensembl chr19:57,571,566...57,578,911 		JBrowse link
negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940)
(PMID:23824195)		 MGI PMID:18302940 PMID:23824195 NCBI chr10:97,572,441...97,583,884
Ensembl chr10:97,572,499...97,583,884 		JBrowse link
G BDNF brain derived neurotrophic factor involved_in ISS ParkinsonsUK-UCL GO_REF:0000024 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:98,211,439...98,215,457
Ensembl chr 7:98,211,439...98,215,457 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037 		JBrowse link
G CCN3 cellular communication network factor 3 involved_in IDA (PMID:12050162) UniProt PMID:12050162 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434 		JBrowse link
G CEACAM5 CEA cell adhesion molecule 5 involved_in IDA (PMID:10931872), (PMID:8408226) UniProt PMID:8408226 PMID:10931872 NCBI chr19:41,708,626...41,730,433
Ensembl chr19:41,708,585...41,730,433 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:7737360 RGD:151665771 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:19308989 RGD:9587764 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G HDAC1 histone deacetylase 1 NOT|involved_in IMP (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC3 histone deacetylase 3 NOT|involved_in IMP (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849 		JBrowse link
G HDAC4 histone deacetylase 4 involved_in IMP (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HDAC5 histone deacetylase 5 involved_in IMP (PMID:10983972), (PMID:11081517) BHF-UCL PMID:10983972 PMID:11081517 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G MIR200B microRNA 200b involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MYOCD myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17940050) Ensembl
MGI		 PMID:17940050 GO_REF:0000107 NCBI chr17:12,665,890...12,768,949
Ensembl chr17:12,665,890...12,768,949 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IMP (PMID:15653675) BHF-UCL PMID:15653675 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G PLPP7 phospholipid phosphatase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19704009) Ensembl
MGI		 PMID:19704009 GO_REF:0000107 NCBI chr 9:131,289,723...131,309,261
Ensembl chr 9:131,289,459...131,359,022 		JBrowse link
G RPL3L ribosomal protein L3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,943,974...1,954,689
Ensembl chr16:1,943,974...1,957,606 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:108,589,851...108,598,084
Ensembl chr12:108,589,851...108,598,320 		JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr16:31,214,119...31,231,537
Ensembl chr16:31,214,119...31,231,537 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    negative regulation of biological process 6545
      negative regulation of developmental process 1212
        negative regulation of cell differentiation 870
          negative regulation of muscle cell differentiation 86
            negative regulation of striated muscle cell differentiation 53
              negative regulation of cardiac muscle cell differentiation + 12
              negative regulation of cardiac muscle fiber development 0
              negative regulation of cell growth involved in cardiac muscle cell development 19
              negative regulation of myotube differentiation + 21
              negative regulation of skeletal muscle fiber development 0
Path 2
Term Annotations click to browse term
  biological_process 19770
    developmental process 7625
      cellular developmental process 5185
        cell differentiation 5184
          muscle cell differentiation 534
            regulation of muscle cell differentiation 204
              regulation of striated muscle cell differentiation 128
                negative regulation of striated muscle cell differentiation 53
                  negative regulation of cardiac muscle cell differentiation + 12
                  negative regulation of cardiac muscle fiber development 0
                  negative regulation of cell growth involved in cardiac muscle cell development 19
                  negative regulation of myotube differentiation + 21
                  negative regulation of skeletal muscle fiber development 0
paths to the root