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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of striated muscle cell differentiation
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Accession:GO:0051154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms:exact_synonym: down regulation of striated muscle cell differentiation;   downregulation of striated muscle cell differentiation
 narrow_synonym: inhibition of striated muscle cell differentiation


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negative regulation of striated muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15520282) Ensembl
MGI		 PMID:15520282 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20004191) Ensembl
MGI		 PMID:20004191 GO_REF:0000107 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447 		JBrowse link
G YBX1 Y-box binding protein 1 acts_upstream_of_or_within ISO (PMID:20004191) MGI PMID:20004191 NCBI chr15:646,301...666,347
Ensembl chr15:646,584...666,329 		JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:27302109 RGD:151660350 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5902683|PMID:18371447) BHF-UCL PMID:18371447 MGI:5902683 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:11,445,843...11,552,325
Ensembl chr10:11,539,994...11,552,890 		JBrowse link
G FZD7 frizzled class receptor 7 involved_in ISO (PMID:23939491) BHF-UCL PMID:23939491 NCBI chr37:11,054,572...11,061,173
Ensembl chr37:11,053,521...11,060,821 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24565863) Ensembl
MGI		 PMID:24565863 GO_REF:0000107 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682 		JBrowse link
G MIR590 microRNA mir-590 involved_in ISO (PMID:25163461) BHF-UCL PMID:25163461 NCBI chr 6:6,186,538...6,186,598
Ensembl chr 6:6,186,538...6,186,598 		JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:38,737,072...39,320,257
Ensembl chr21:38,737,247...39,216,549 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO RGD PMID:19358331 RGD:2312604 NCBI chr 9:31,884,028...31,908,142
Ensembl chr 9:31,885,478...31,904,386 		JBrowse link
G CAV3 caveolin 3 ISO RGD PMID:21170593 RGD:6784534 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196 		JBrowse link
G CTDP1 CTD phosphatase subunit 1 ISO RGD PMID:22569295 RGD:9686371 NCBI chr 1:886,973...945,994
Ensembl chr 1:762,020...946,142 		JBrowse link
G FOXP1 forkhead box P1 ISO RGD PMID:26333362 RGD:11561912 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24190878 RGD:10449133 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G MIR451 microRNA mir-451 ISO RGD PMID:25209900 RGD:11558015 NCBI chr 9:43,030,863...43,030,931
Ensembl chr 9:43,030,863...43,030,931 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:22082674 RGD:11533929 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PI16 peptidase inhibitor 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17909105) Ensembl
MGI		 PMID:17909105 GO_REF:0000107 NCBI chr12:6,017,312...6,027,048
Ensembl chr12:6,017,522...6,026,307 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO RGD PMID:22198280 RGD:5687133 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G RBM10 RNA binding motif protein 10 ISO RGD PMID:30257214 RGD:151667449 NCBI chr  X:40,746,959...40,776,764
Ensembl chr  X:40,747,178...40,776,742 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:16380388 RGD:13524577 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9918533 RGD:7207376 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 ISO RGD PMID:25022898 RGD:13464131 NCBI chr33:6,976,322...7,009,618
Ensembl chr33:6,976,934...7,009,594 		JBrowse link
G YY1 YY1 transcription factor ISO RGD PMID:18632988 RGD:9588273 NCBI chr 8:68,539,511...68,572,796
Ensembl chr 8:68,539,353...68,568,058 		JBrowse link
negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940)
(PMID:23824195)		 MGI PMID:18302940 PMID:23824195 NCBI chr28:10,838,677...10,848,406
Ensembl chr28:10,834,411...10,848,406 		JBrowse link
G BDNF brain derived neurotrophic factor involved_in ISO PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 involved_in ISO (MGI:5607242|PMID:17612490) UniProt PMID:17612490 MGI:5607242 NCBI chr 6:11,112,233...11,115,776
Ensembl chr 6:11,114,694...11,115,257 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:21,464,302...21,469,119 JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:18,507,586...18,515,755
Ensembl chr13:18,507,580...18,514,619 		JBrowse link
G CEACAM28 carcinoembryonic antigen-related cell adhesion molecule 28 involved_in ISO (PMID:10931872), (PMID:8408226) UniProt PMID:8408226 PMID:10931872 NCBI chr 1:111,812,571...111,834,985
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:7737360 RGD:151665771 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:19308989 RGD:9587764 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G HDAC1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186 		JBrowse link
G HDAC3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682 		JBrowse link
G HDAC4 histone deacetylase 4 involved_in ISO (PMID:10983972) BHF-UCL PMID:10983972 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G HDAC5 histone deacetylase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,261,075...19,297,669
Ensembl chr 9:19,260,893...19,297,623 		JBrowse link
G MYOCD myocardin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17940050) Ensembl
MGI		 PMID:17940050 GO_REF:0000107 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:39,240,755...39,254,585
Ensembl chr 4:39,244,286...39,247,592 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G PLPP7 phospholipid phosphatase 7 (inactive) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19704009) Ensembl
MGI		 PMID:19704009 GO_REF:0000107 NCBI chr 9:52,781,110...52,796,763
Ensembl chr 9:52,781,020...52,796,433 		JBrowse link
G RPL3L ribosomal protein L3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,971,098...38,981,466
Ensembl chr 6:38,974,018...38,982,012 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409 		JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr 6:17,031,175...17,053,399
Ensembl chr 6:17,031,913...17,039,556 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) UniProt PMID:17612490 MGI:5607242 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    negative regulation of biological process 5554
      negative regulation of developmental process 1063
        negative regulation of cell differentiation 761
          negative regulation of muscle cell differentiation 81
            negative regulation of striated muscle cell differentiation 47
              negative regulation of cardiac muscle cell differentiation + 10
              negative regulation of cardiac muscle fiber development 0
              negative regulation of cell growth involved in cardiac muscle cell development 15
              negative regulation of myotube differentiation + 20
              negative regulation of skeletal muscle fiber development 0
Path 2
Term Annotations click to browse term
  biological_process 17068
    developmental process 6529
      cellular developmental process 4356
        cell differentiation 4355
          muscle cell differentiation 462
            regulation of muscle cell differentiation 180
              regulation of striated muscle cell differentiation 113
                negative regulation of striated muscle cell differentiation 47
                  negative regulation of cardiac muscle cell differentiation + 10
                  negative regulation of cardiac muscle fiber development 0
                  negative regulation of cell growth involved in cardiac muscle cell development 15
                  negative regulation of myotube differentiation + 20
                  negative regulation of skeletal muscle fiber development 0
paths to the root