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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of striated muscle cell differentiation
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Accession:GO:0051154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms:exact_synonym: down regulation of striated muscle cell differentiation;   downregulation of striated muscle cell differentiation
 narrow_synonym: inhibition of striated muscle cell differentiation



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negative regulation of striated muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:3057067|PMID:15520282) RGD PMID:15520282 MGI:3057067 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G LOC100912427 nuclease-sensitive element-binding protein 1-like acts_upstream_of_or_within ISO (MGI:4440723|PMID:20004191) RGD PMID:20004191 MGI:4440723 NCBI chr 1:171,304,587...171,306,092
Ensembl chr 1:171,304,774...171,306,097
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:99146 (MGI:4440723|PMID:20004191) RGD PMID:20004191 MGI:4440723 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Ybx1 Y box binding protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4440723|PMID:20004191)
GO_REF:0000107
RGD
Ensembl
PMID:20004191 GO_REF:0000107 MGI:4440723 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
ISS
(PMID:18545679)
GO_REF:0000024
RGD
UniProt
PMID:18545679 GO_REF:0000024 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Ccnd2 cyclin D2 IDA RGD PMID:27302109 RGD:151660350 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5902683|PMID:18371447)
Ensembl
RGD
PMID:18371447 GO_REF:0000107 MGI:5902683 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in ISO UniProtKB:O75084 (PMID:23939491) RGD PMID:23939491 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO UniProtKB:Q8WU20 (PMID:23939491) RGD PMID:23939491 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G Hdac3 histone deacetylase 3 acts_upstream_of_or_within ISO (MGI:5571645|PMID:24565863) RGD PMID:24565863 MGI:5571645 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO (PMID:20081117) RGD PMID:20081117 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3689643|PMID:16151019)
Ensembl
RGD
PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242
JBrowse link
negative regulation of myotube differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (MGI:3796961|PMID:18302940), (MGI:5527051|PMID:23824195) RGD PMID:18302940 PMID:23824195 MGI:3796961 MGI:5527051 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in IMP PMID:16723531 BHF-UCL PMID:16723531 RGD:1580249 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 involved_in ISS
ISO
GO_REF:0000024
(MGI:5607242|PMID:17612490)
UniProt
RGD
PMID:17612490 GO_REF:0000024 MGI:5607242 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 involved_in ISO (MGI:5297791|PMID:12657651) RGD PMID:12657651 MGI:5297791 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:12050162)
UniProt
RGD
PMID:12050162 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:7737360 RGD:151665771 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Daxx death-domain associated protein IDA RGD PMID:19308989 RGD:9587764 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Hdac1 histone deacetylase 1 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac3 histone deacetylase 3 NOT|involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (PMID:10983972) RGD PMID:10983972 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdac5 histone deacetylase 5 involved_in ISO (PMID:10983972), (PMID:11081517) RGD PMID:10983972 PMID:11081517 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Myocd myocardin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3849559 (MGI:3849299|PMID:17940050)
Ensembl
RGD
PMID:17940050 GO_REF:0000107 MGI:3849299 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in ISO
IEA
(PMID:15653675)
GO_REF:0000107
RGD
Ensembl
PMID:15653675 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5319604|PMID:18299578)
UniProt
RGD
PMID:18299578 GO_REF:0000024 MGI:5319604 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Plpp7 phospholipid phosphatase 7 (inactive) acts_upstream_of_or_within ISO MGI:1928394 (MGI:4366685|PMID:19704009) RGD PMID:19704009 MGI:4366685 NCBI chr 3:15,384,461...15,398,820
Ensembl chr 3:15,384,492...15,398,883
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:6294241|PMID:22579779) RGD PMID:22579779 MGI:6294241 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689
JBrowse link
G Trim72 tripartite motif containing 72 acts_upstream_of_or_within ISO (MGI:5602876|PMID:23965929) RGD PMID:23965929 MGI:5602876 NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (MGI:5607242|PMID:17612490) RGD PMID:17612490 MGI:5607242 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    negative regulation of biological process 5769
      negative regulation of developmental process 1080
        negative regulation of cell differentiation 775
          negative regulation of muscle cell differentiation 75
            negative regulation of striated muscle cell differentiation 45
              negative regulation of cardiac muscle cell differentiation + 9
              negative regulation of cardiac muscle fiber development 0
              negative regulation of cell growth involved in cardiac muscle cell development 15
              negative regulation of myotube differentiation + 18
              negative regulation of skeletal muscle fiber development 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      cellular developmental process 4533
        cell differentiation 4510
          muscle cell differentiation 466
            regulation of muscle cell differentiation 174
              regulation of striated muscle cell differentiation 115
                negative regulation of striated muscle cell differentiation 45
                  negative regulation of cardiac muscle cell differentiation + 9
                  negative regulation of cardiac muscle fiber development 0
                  negative regulation of cell growth involved in cardiac muscle cell development 15
                  negative regulation of myotube differentiation + 18
                  negative regulation of skeletal muscle fiber development 0
paths to the root