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ONTOLOGY REPORT - ANNOTATIONS

Term:smooth muscle cell differentiation
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Accession:GO:0051145 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
Synonyms:exact_synonym: nonstriated muscle cell differentiation


show annotations for term's descendants           Sort by:
smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 acts_upstream_of_or_within ISO MGI:2386570|MGI:2651395 (MGI:3703113|PMID:17078885) RGD PMID:17078885 MGI:3703113 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2183545 (MGI:1313232|PMID:9788961) RGD PMID:9788961 MGI:1313232 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624584|PMID:16546160)
GO_REF:0000107		 RGD
Ensembl		 PMID:16546160 GO_REF:0000107 MGI:3624584 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2148567|MGI:3577106 (MGI:4359548|PMID:19690384)
GO_REF:0000107		 RGD
Ensembl		 PMID:19690384 GO_REF:0000107 MGI:4359548 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:3629660 (MGI:3716020|PMID:17560563) RGD PMID:17560563 MGI:3716020 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:1929432|MGI:88180 (MGI:2135612|PMID:11493558), (MGI:3766861|PMID:17881493) RGD PMID:11493558 PMID:17881493 MGI:2135612 MGI:3766861 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G Gata6 GATA binding protein 6 involved_in ISO (PMID:17626241) RGD PMID:17626241 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Itga8 integrin subunit alpha 8 involved_in ISO (MGI:4947862|PMID:21335239) RGD PMID:21335239 MGI:4947862 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:1857491 (MGI:1298294|PMID:9778514) RGD PMID:9778514 MGI:1298294 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mrtfa myocardin related transcription factor A involved_in IBA
ISO		 PMID:21873635
(PMID:14970199)		 RGD PMID:14970199 PMID:21873635 RGD:13792537 NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418 		JBrowse link
G Myocd myocardin acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 MGI:3052940|MGI:3773718 (MGI:2670236|PMID:12867591), (MGI:3773460|PMID:18188448), (MGI:4941650|PMID:21357509)
(PMID:14970199), (PMID:15907818)
PMID:21873635		 RGD PMID:12867591 PMID:14970199 PMID:15907818 PMID:18188448 PMID:21357509 More... MGI:2670236 MGI:3773460 MGI:4941650, RGD:1299359, RGD:13792537 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4947862|PMID:21335239) RGD PMID:21335239 MGI:4947862 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (MGI:3505802|PMID:15497153) RGD PMID:15497153 MGI:3505802 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Tbx18 T-box transcription factor 18 acts_upstream_of_or_within ISO MGI:3044914 (MGI:3618666|PMID:16511601) RGD PMID:16511601 MGI:3618666 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058 		JBrowse link
G Tbx2 T-box transcription factor 2 acts_upstream_of_or_within ISO MGI:98495 (MGI:6284231|PMID:30478225) RGD PMID:30478225 MGI:6284231 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:98494 (MGI:6284231|PMID:30478225) RGD PMID:30478225 MGI:6284231 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tmem204 transmembrane protein 204 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:4443218|PMID:20439428)
PMID:21873635		 RGD PMID:20439428 PMID:21873635 MGI:4443218, RGD:13792537 NCBI chr10:14,076,518...14,104,849
Ensembl chr10:14,076,519...14,101,920 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO MGI:1857453 (MGI:3624584|PMID:16546160) RGD PMID:16546160 MGI:3624584 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO MGI:3641208 (MGI:4359548|PMID:19690384) RGD PMID:19690384 MGI:4359548 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
aortic smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 acts_upstream_of_or_within ISO (MGI:5007924|PMID:19342595) RGD PMID:19342595 MGI:5007924 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:5007924|PMID:19342595) RGD PMID:19342595 MGI:5007924 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
cardiac vascular smooth muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:2447620 (MGI:4838384|PMID:20619341) RGD PMID:20619341 MGI:4838384 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:5298073|PMID:21311046) RGD PMID:21311046 MGI:5298073 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:4461879|PMID:18093989) RGD PMID:18093989 MGI:4461879 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11889139), (PMID:12615657)		 Ensembl
RGD		 PMID:11889139 PMID:12615657 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18297060) RGD PMID:18297060 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mir143 microRNA 143 acts_upstream_of_or_within ISO MGI:2676830 (MGI:4443305|PMID:19816508) RGD PMID:19816508 MGI:4443305 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir145 microRNA 145 acts_upstream_of_or_within ISO MGI:2676828 (MGI:4443305|PMID:19816508) RGD PMID:19816508 MGI:4443305 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Myocd myocardin involved_in IDA PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3522214 (MGI:3513738|PMID:15569937) RGD PMID:15569937 MGI:3513738 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
enteric smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednrb endothelin receptor type B involved_in ISO (MGI:1330409|PMID:10021336) RGD PMID:10021336 MGI:1330409 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
kidney smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tshz3 teashirt zinc finger homeobox 3 involved_in ISO (MGI:3806378|PMID:18776146) RGD PMID:18776146 MGI:3806378 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874 		JBrowse link
negative regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir21 microRNA 21 involved_in ISO (PMID:22034194) RGD PMID:22034194 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in IDA PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
negative regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:2388350|PMID:12399320)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12399320 GO_REF:0000024 GO_REF:0000107 MGI:2388350 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
negative regulation of smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 acts_upstream_of_or_within ISO MGI:4360512 (MGI:4360129|PMID:19619540) RGD PMID:19619540 MGI:4360129 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ereg epiregulin involved_in ISO
ISS		 (PMID:14581411)
GO_REF:0000024		 RGD
UniProt		 PMID:14581411 GO_REF:0000024 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Foxo4 forkhead box O4 involved_in ISO (PMID:16054032) RGD PMID:16054032 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (PMID:18239137) RGD PMID:18239137 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:5284767|PMID:18239137) RGD PMID:18239137 MGI:5284767 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Mecp2 methyl CpG binding protein 2 involved_in ISO (MGI:5811980|PMID:25722434) RGD PMID:25722434 MGI:5811980 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Med28 mediator complex subunit 28 acts_upstream_of_or_within ISO (MGI:3762062|PMID:17848560) RGD PMID:17848560 MGI:3762062 NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583 		JBrowse link
G Prdm6 PR/SET domain 6 acts_upstream_of_or_within ISO (MGI:3619789|PMID:16537907) RGD PMID:16537907 MGI:3619789 NCBI chr18:46,904,115...47,008,482
Ensembl chr18:46,904,127...47,007,823 		JBrowse link
G Rbpms2 RNA binding protein, mRNA processing factor 2 involved_in ISO
IBA		 (PMID:25064856)
PMID:21873635		 RGD PMID:25064856 PMID:21873635 RGD:13792537 NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268 		JBrowse link
G Rcan1 regulator of calcineurin 1 IDA RGD PMID:15148306 RGD:1581653 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045 		JBrowse link
negative regulation of ureter smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2388350|PMID:12399320)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12399320 GO_REF:0000024 GO_REF:0000107 MGI:2388350 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
negative regulation of vascular associated smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir100 microRNA 100 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir15b microRNA 15b involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:18548003), (PMID:19088079) RGD PMID:18548003 PMID:19088079 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:20857419) RGD PMID:20857419 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (PMID:23853098) RGD PMID:23853098 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 involved_in ISO (PMID:23853098) RGD PMID:23853098 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 involved_in ISO (PMID:23853098) RGD PMID:23853098 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO		 GO_REF:0000107
(PMID:19088079)		 Ensembl
RGD		 PMID:19088079 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA		 (PMID:27021683)
GO_REF:0000107		 RGD
Ensembl		 PMID:27021683 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in IMP PMID:28259995 BHF-UCL PMID:28259995 RGD:13601993 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
positive regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cth cystathionine gamma-lyase involved_in ISO
IEA		 (PMID:21659522)
GO_REF:0000107		 RGD
Ensembl		 PMID:21659522 GO_REF:0000107 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 involved_in ISO (MGI:4947512|PMID:20019329) RGD PMID:20019329 MGI:4947512 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA		 (PMID:23840305)
GO_REF:0000107		 RGD
Ensembl		 PMID:23840305 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
positive regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:2388350|PMID:12399320)		 Ensembl
UniProt
RGD		 PMID:12399320 GO_REF:0000024 GO_REF:0000107 MGI:2388350 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
positive regulation of smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:25526086) RGD PMID:25526086 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Myocd myocardin involved_in ISO
IEA		 (PMID:18451334)
GO_REF:0000107		 RGD
Ensembl		 PMID:18451334 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Notch1 notch receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18239137)		 Ensembl
RGD		 PMID:18239137 GO_REF:0000107 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18239137)		 Ensembl
RGD		 PMID:18239137 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Notch4 notch receptor 4 involved_in ISO (PMID:18239137) RGD PMID:18239137 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Olfm2 olfactomedin 2 involved_in ISO
ISS		 (PMID:25298399)
GO_REF:0000024		 RGD
UniProt		 PMID:25298399 GO_REF:0000024 NCBI chr 8:19,204,472...19,282,154
Ensembl chr 8:19,204,475...19,282,117 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 IMP RGD PMID:16135793 RGD:2303115 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5810254|PMID:25526086)
GO_REF:0000107		 RGD
Ensembl		 PMID:25526086 GO_REF:0000107 MGI:5810254 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 IDA RGD PMID:23110084 RGD:9586362 NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within IDA PMID:8616889 MGI PMID:8616889 RGD:8553354 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 acts_upstream_of_or_within ISO MGI:3810527 (MGI:3806378|PMID:18776146) RGD PMID:18776146 MGI:3806378 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874 		JBrowse link
positive regulation of ureter smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:2388350|PMID:12399320)		 UniProt
Ensembl
RGD		 PMID:12399320 GO_REF:0000024 GO_REF:0000107 MGI:2388350 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
positive regulation of vascular associated smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Mir125b1 microRNA 125b-1 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir140 microRNA 140 involved_in ISO (PMID:27021683) RGD PMID:27021683 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir145 microRNA 145 IMP RGD PMID:19542014 RGD:13210556 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:27021683) RGD PMID:27021683 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdc4 syndecan 4 NOT|involved_in IDA PMID:25089138 BHF-UCL PMID:25089138 RGD:11079193 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
regulation of smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1347470 (MGI:3766861|PMID:17881493)		 Ensembl
RGD		 PMID:17881493 GO_REF:0000107 MGI:3766861 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 NAS RGD PMID:9642040 RGD:1299488 NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3629660 (MGI:3688953|PMID:16989802) RGD PMID:16989802 MGI:3688953 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Myocd myocardin IMP RGD PMID:12756293 RGD:1299358 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3641341|PMID:16824956)		 Ensembl
RGD		 PMID:16824956 GO_REF:0000107 MGI:3641341 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
ureter smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:2655195 (MGI:4437379|PMID:20110314) RGD PMID:20110314 MGI:4437379 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2176205|MGI:2385468 (MGI:4848001|PMID:20881014) RGD PMID:20881014 MGI:4848001 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 involved_in ISO (MGI:3806378|PMID:18776146) RGD PMID:18776146 MGI:3806378 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874 		JBrowse link
vascular associated smooth muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (MGI:3772552|PMID:18097473) RGD PMID:18097473 MGI:3772552 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5318950|PMID:21350216)		 Ensembl
RGD		 PMID:21350216 GO_REF:0000107 MGI:5318950 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO
IEA		 MGI:2687362 (MGI:5585582|PMID:24412386)
GO_REF:0000107		 RGD
Ensembl		 PMID:24412386 GO_REF:0000107 MGI:5585582 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 involved_in ISO (MGI:5584046|PMID:23636094) RGD PMID:23636094 MGI:5584046 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Eng endoglin involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4453944|PMID:20122914)		 Ensembl
RGD		 PMID:20122914 GO_REF:0000107 MGI:4453944 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 acts_upstream_of_or_within ISO MGI:1920431 (MGI:2136698|PMID:11439183) RGD PMID:11439183 MGI:2136698 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO MGI:103296 (MGI:2136698|PMID:11439183) RGD PMID:11439183 MGI:2136698 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3772552|PMID:18097473)		 UniProt
RGD		 PMID:18097473 GO_REF:0000024 MGI:3772552 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Sgcb sarcoglycan, beta acts_upstream_of_or_within ISO MGI:2153048 (MGI:1352919|PMID:10678176) RGD PMID:10678176 MGI:1352919 NCBI chr14:34,563,614...34,578,614
Ensembl chr14:34,563,608...34,578,583 		JBrowse link
vascular associated smooth muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor involved_in ISO (MGI:5584055|PMID:23603510) RGD PMID:23603510 MGI:5584055 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G C3 complement C3 acts_upstream_of_or_within ISO (MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:5883383 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cfd complement factor D acts_upstream_of_or_within ISO (MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:5883383 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:5883383 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 IEP RGD PMID:22398275 RGD:9587795 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Mrtfb myocardin related transcription factor B acts_upstream_of_or_within ISO MGI:3608959 (MGI:3607644|PMID:16204380) RGD PMID:16204380 MGI:3607644 NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897 		JBrowse link
G Myocd myocardin involved_in IEA
ISO		 GO_REF:0000107
RNAcentral:URS0000527F89_10090 (MGI:4354665|PMID:19578358)		 Ensembl
RGD		 PMID:19578358 GO_REF:0000107 MGI:4354665 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 acts_upstream_of_or_within ISO MGI:1920431 (MGI:2136698|PMID:11439183) RGD PMID:11439183 MGI:2136698 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO MGI:103296 (MGI:2136698|PMID:11439183) RGD PMID:11439183 MGI:2136698 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:2136268 (MGI:3796777|PMID:18458156) RGD PMID:18458156 MGI:3796777 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Qki QKI, KH domain containing RNA binding acts_upstream_of_or_within
involved_in		 ISO
ISS
IEA		 MGI:3033861 (MGI:3029686|PMID:14706070)
(PMID:31331967)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:14706070 PMID:31331967 GO_REF:0000024 GO_REF:0000107 MGI:3029686 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular developmental process 4642
        cell differentiation 4641
          muscle cell differentiation 479
            smooth muscle cell differentiation 90
              enteric smooth muscle cell differentiation 1
              kidney smooth muscle cell differentiation + 2
              negative regulation of smooth muscle cell differentiation + 23
              positive regulation of smooth muscle cell differentiation + 23
              regulation of smooth muscle cell differentiation + 49
              smooth muscle cell differentiation involved in prostate glandular acinus development 0
              ureter smooth muscle cell differentiation + 4
              vascular associated smooth muscle cell differentiation + 48
paths to the root