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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of actin nucleation
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Accession:GO:0051127 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms:exact_synonym: up regulation of actin nucleation;   upregulation of actin nucleation
 narrow_synonym: activation of actin nucleation;   stimulation of actin nucleation


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positive regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmn1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) RGD PMID:14647292 MGI:3027450 NCBI chr 3:100,101,103...100,485,652 JBrowse link
G Gsn gelsolin involved_in ISO (PMID:19666531) RGD PMID:19666531 NCBI chr 3:18,585,166...18,638,404 JBrowse link
G Magel2 MAGE family member L2 acts_upstream_of_or_within ISO MGI:1916017 (MGI:5603599|PMID:23452853) RGD PMID:23452853 MGI:5603599 NCBI chr 1:115,880,137...115,884,680 JBrowse link
G Scin scinderin involved_in ISO (PMID:19666531) RGD PMID:19666531 NCBI chr 6:57,110,128...57,188,059 JBrowse link
G Trim27 tripartite motif-containing 27 acts_upstream_of_or_within ISO MGI:1916017 (MGI:5603599|PMID:23452853) RGD PMID:23452853 MGI:5603599 NCBI chr17:43,538,282...43,550,633 JBrowse link
G Whamm WASP homolog associated with actin, golgi membranes and microtubules involved_in ISO (PMID:18614018) RGD PMID:18614018 NCBI chr 1:135,526,363...135,557,091 JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 9:61,856,379...61,904,029 JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 4:146,750,821...146,766,050 JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) RGD PMID:21107423 NCBI chr 1:106,710,924...106,799,393 JBrowse link
G Fchsd2 FCH and double SH3 domains 2 involved_in ISO (PMID:29887380) RGD PMID:29887380 NCBI chr 1:155,444,471...155,685,539 JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO
IEA
(PMID:21107423)
GO_REF:0000107
RGD
Ensembl
PMID:21107423 GO_REF:0000107 NCBI chr 3:65,417,450...65,491,769 JBrowse link
G RGD1561552 similar to WASP family 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:73,040,984...73,043,716 JBrowse link
G Was WASP actin nucleation promoting factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:14,405,096...14,413,850 JBrowse link
G Wasf1 WASP family member 1 involved_in ISO
IBA
(PMID:21107423)
PMID:21873635
RGD PMID:21107423, PMID:21873635 RGD:13792537 NCBI chr20:44,325,815...44,372,999 JBrowse link
G Wasf2 WASP family member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:145,336,816...145,402,041 JBrowse link
G Wasf3 WASP family member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:8,563,805...8,660,799 JBrowse link
G Wasl WASP like actin nucleation promoting factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:53,083,536...53,132,061 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      positive regulation of cellular process 6067
        positive regulation of cellular component organization 1278
          positive regulation of supramolecular fiber organization 217
            positive regulation of actin filament polymerization 99
              positive regulation of actin nucleation 17
                positive regulation of Arp2/3 complex-mediated actin nucleation 11
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cellular component organization or biogenesis 6723
        cellular component organization 6483
          organelle organization 4060
            cytoskeleton organization 1453
              actin cytoskeleton organization 746
                actin filament organization 467
                  actin polymerization or depolymerization 232
                    regulation of actin polymerization or depolymerization 200
                      regulation of actin filament polymerization 181
                        positive regulation of actin filament polymerization 99
                          actin nucleation 51
                            regulation of actin nucleation 32
                              positive regulation of actin nucleation 17
                                positive regulation of Arp2/3 complex-mediated actin nucleation 11
paths to the root