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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of actin nucleation
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Accession:GO:0051126 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms:exact_synonym: down regulation of actin nucleation;   downregulation of actin nucleation
 narrow_synonym: inhibition of actin nucleation



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negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in ISO
IBA
(PMID:24132237)
PMID:21873635
RGD PMID:24132237 PMID:21873635 RGD:13792537 NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124
JBrowse link
G Coro1a coronin 1A involved_in ISO (PMID:17442961) RGD PMID:17442961 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin 1B involved_in IEA
ISO
GO_REF:0000107
(PMID:17350576), (PMID:18775315)
Ensembl
RGD
PMID:17350576 PMID:18775315 GO_REF:0000107 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:30013181) RGD PMID:30013181 NCBI chr 4:109,293,978...110,443,413
Ensembl chr 4:109,293,978...110,443,522
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO (PMID:32128961) RGD PMID:32128961 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173
JBrowse link
G Gmfb glia maturation factor, beta involved_in IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gmfg glia maturation factor, gamma involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000002
PMID:21873635
(MGI:5505367|PMID:23727094)
Ensembl
InterPro
RGD
PMID:23727094 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:5505367, RGD:13792537 NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (MGI:5805366|PMID:17318189) RGD PMID:17318189 MGI:5805366 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IDA PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20026
    cellular process 18613
      negative regulation of cellular process 5125
        negative regulation of cellular component organization 775
          negative regulation of supramolecular fiber organization 188
            negative regulation of actin nucleation 9
              negative regulation of Arp2/3 complex-mediated actin nucleation 7
Path 2
Term Annotations click to browse term
  biological_process 20026
    cellular process 18613
      cellular component organization or biogenesis 6778
        cellular component organization 6535
          organelle organization 3668
            cytoskeleton organization 1542
              regulation of cytoskeleton organization 577
                regulation of actin cytoskeleton organization 389
                  regulation of actin filament organization 295
                    regulation of actin nucleation 37
                      negative regulation of actin nucleation 9
                        negative regulation of Arp2/3 complex-mediated actin nucleation 7
paths to the root