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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of actin nucleation
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Accession:GO:0051125 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.


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regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vil1 villin 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:74,448,543...74,474,719
Ensembl chr 1:74,448,535...74,474,718 		JBrowse link
G Washc5 WASH complex subunit 5 acts_upstream_of_or_within
involved_in		 IMP
IBA		 (PMID:27390154) MGI
GO_Central		 PMID:27390154 GO_REF:0000033 NCBI chr15:59,203,712...59,246,043
Ensembl chr15:59,203,846...59,246,016 		JBrowse link
negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:79,575,107...79,585,012
Ensembl chr 7:79,575,109...79,585,107 		JBrowse link
G Coro1a coronin, actin binding protein 1A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959 		JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin, actin binding protein 1B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:4,198,610...4,204,034
Ensembl chr19:4,198,618...4,204,034 		JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:76,858,620...77,956,798
Ensembl chr 6:76,858,620...77,956,682 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:145,746,281...145,813,855
Ensembl chr 3:145,746,281...145,813,885 		JBrowse link
G Gmfb glia maturation factor, beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:47,045,606...47,059,711
Ensembl chr14:47,045,606...47,059,699 		JBrowse link
G Gmfg glia maturation factor, gamma acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:23727094) MGI
GO_Central		 PMID:23727094 GO_REF:0000033 NCBI chr 7:28,136,894...28,147,655
Ensembl chr 7:28,136,872...28,147,658 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in IDA (MGI:5805366|PMID:17318189) ParkinsonsUK-UCL PMID:17318189 MGI:5805366 NCBI chr 5:124,111,665...124,141,263
Ensembl chr 5:124,111,691...124,143,621 		JBrowse link
G Pick1 protein interacting with C kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr15:79,113,373...79,133,666
Ensembl chr15:79,113,373...79,133,684 		JBrowse link
positive regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmn1 formin 1 acts_upstream_of_or_within IDA (PMID:14647292) MGI PMID:14647292 NCBI chr 2:113,158,029...113,547,113
Ensembl chr 2:113,158,081...113,547,112 		JBrowse link
G Gsn gelsolin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Magel2 MAGE family member L2 acts_upstream_of_or_within IGI (PMID:23452853) MGI PMID:23452853 NCBI chr 7:62,026,727...62,031,388
Ensembl chr 7:62,026,758...62,031,388 		JBrowse link
G Scin scinderin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:40,109,768...40,184,227
Ensembl chr12:40,109,768...40,184,227 		JBrowse link
G Trim27 tripartite motif-containing 27 acts_upstream_of_or_within IGI (PMID:23452853) MGI PMID:23452853 NCBI chr13:21,363,570...21,378,893
Ensembl chr13:21,363,615...21,378,894 		JBrowse link
G Whamm WAS protein homolog associated with actin, golgi membranes and microtubules involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:81,220,403...81,246,585
Ensembl chr 7:81,221,014...81,246,584 		JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl interactor 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:60,444,927...60,521,104
Ensembl chr 1:60,448,778...60,520,317 		JBrowse link
G Brk1 BRICK1, SCAR/WAVE actin-nucleating complex subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:113,581,733...113,593,912
Ensembl chr 6:113,581,733...113,593,912 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:55,491,556...55,582,381
Ensembl chr 7:55,491,493...55,582,350 		JBrowse link
G Fchsd2 FCH and double SH3 domains 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:100,757,836...100,933,613
Ensembl chr 7:100,742,070...100,933,612 		JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:80,330,856...80,411,526
Ensembl chr 2:80,330,856...80,411,724 		JBrowse link
G Wasf1 WASP family, member 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:40,759,476...40,814,565
Ensembl chr10:40,759,471...40,814,566 		JBrowse link
G Wasf2 WASP family, member 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:132,857,843...132,927,067
Ensembl chr 4:132,857,816...132,927,067 		JBrowse link
G Wasf3 WASP family, member 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:146,317,411...146,410,425
Ensembl chr 5:146,321,795...146,410,425 		JBrowse link
G Wmp WAVE homology in membrane protrusions involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:106,989,341...106,992,042
Ensembl chr  X:106,989,341...106,992,071 		JBrowse link
regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1ar adaptor-related protein complex 1 associated regulatory protein acts_upstream_of_or_within IMP
IGI		 (PMID:22689987) MGI PMID:22689987 NCBI chr 3:127,600,656...127,631,148
Ensembl chr 3:127,600,656...127,631,172 		JBrowse link
G Arf1 ADP-ribosylation factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:59,102,237...59,119,042
Ensembl chr11:59,102,238...59,119,096 		JBrowse link
G Arfip1 ADP-ribosylation factor interacting protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:84,403,400...84,490,075
Ensembl chr 3:84,403,733...85,794,825
Ensembl chr 3:84,403,733...85,794,825 		JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:105,283,408...105,289,623
Ensembl chr 7:105,283,410...105,289,623 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:24,196,464...24,464,983
Ensembl chr13:24,196,327...24,464,778 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:106,412,642...106,424,827
Ensembl chr 8:106,412,906...106,424,819 		JBrowse link
G Carmil3 capping protein regulator and myosin 1 linker 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:55,728,108...55,745,729
Ensembl chr14:55,728,108...55,745,729 		JBrowse link
G Pick1 protein interacting with C kinase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:79,113,373...79,133,666
Ensembl chr15:79,113,373...79,133,684 		JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:140,740,239...140,752,764
Ensembl chr 7:140,740,239...140,752,770 		JBrowse link
G Washc1 WASH complex subunit 1 involved_in NAS (MGI:4415646|PMID:19922875) ComplexPortal PMID:19922875 MGI:4415646 NCBI chr17:66,418,524...66,427,498
Ensembl chr17:66,418,540...66,427,498 		JBrowse link
G Washc2 WASH complex subunit 2 involved_in NAS (MGI:4415646|PMID:19922875) ComplexPortal PMID:19922875 MGI:4415646 NCBI chr 6:116,184,988...116,239,632
Ensembl chr 6:116,184,999...116,239,647 		JBrowse link
G Washc3 WASH complex subunit 3 involved_in NAS (MGI:4415646|PMID:19922875) ComplexPortal PMID:19922875 MGI:4415646 NCBI chr10:88,036,954...88,160,001
Ensembl chr10:88,036,955...88,082,020 		JBrowse link
G Washc4 WASH complex subunit 4 involved_in NAS (MGI:4415646|PMID:19922875) ComplexPortal PMID:19922875 MGI:4415646 NCBI chr10:83,379,073...83,432,350
Ensembl chr10:83,379,616...83,432,337 		JBrowse link
G Washc5 WASH complex subunit 5 involved_in NAS (MGI:4415646|PMID:19922875) ComplexPortal PMID:19922875 MGI:4415646 NCBI chr15:59,203,712...59,246,043
Ensembl chr15:59,203,846...59,246,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      regulation of cellular process 12175
        regulation of actin filament-based process 416
          regulation of actin cytoskeleton organization 366
            regulation of actin filament organization 288
              regulation of actin nucleation 38
                negative regulation of actin nucleation + 9
                positive regulation of actin nucleation + 15
                regulation of Arp2/3 complex-mediated actin nucleation + 29
Path 2
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      cellular component organization or biogenesis 6936
        cellular component organization 6712
          organelle organization 3678
            cytoskeleton organization 1522
              actin cytoskeleton organization 740
                actin filament organization 482
                  actin nucleation 61
                    regulation of actin nucleation 38
                      negative regulation of actin nucleation + 9
                      positive regulation of actin nucleation + 15
                      regulation of Arp2/3 complex-mediated actin nucleation + 29
paths to the root