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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of binding
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Accession:GO:0051098 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


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desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO RGD PMID:20705669 RGD:5509896 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
negative regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC2 histone deacetylase 2 ISO RGD PMID:21383775 RGD:9590238 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO Rela RGD PMID:17473852 RGD:5688754 NCBI chr11:21,290,603...21,363,701
Ensembl chr11:21,290,621...21,505,122 		JBrowse link
G ID1 inhibitor of DNA binding 1 ISO RGD PMID:7623812 RGD:9686118 NCBI chr24:21,094,339...21,096,276
Ensembl chr24:21,094,755...21,096,276 		JBrowse link
G SIRT1 sirtuin 1 ISO Rela RGD PMID:22044919 RGD:10047123 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
negative regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAP1GAP RAP1 GTPase activating protein ISO RGD PMID:19066305 RGD:9835342 NCBI chr 2:77,509,592...77,554,620
Ensembl chr 2:77,527,914...77,544,205 		JBrowse link
negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr26:6,011,280...6,022,562
Ensembl chr26:6,011,301...6,022,518 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta ISO RGD PMID:9582312 RGD:1581075 NCBI chr17:21,321,329...21,326,357
Ensembl chr17:21,321,349...21,326,244 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056 		JBrowse link
negative regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADNP activity dependent neuroprotector homeobox ISO beta-amyloid aggregation RGD PMID:14706557 RGD:2312790 NCBI chr24:37,211,776...37,245,938
Ensembl chr24:37,213,942...37,243,702 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:9553145 RGD:2303817 NCBI chr 1:75,499,334...75,511,525
Ensembl chr 1:75,499,393...75,511,425 		JBrowse link
G ID1 inhibitor of DNA binding 1 ISO RGD PMID:23831032 RGD:9686139 NCBI chr24:21,094,339...21,096,276
Ensembl chr24:21,094,755...21,096,276 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:24636259 RGD:12789709 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:20802490 RGD:152995511 NCBI chr 2:45,359,865...45,365,496
Ensembl chr 2:45,360,374...45,367,441 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO RGD PMID:22198280 RGD:5687133 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PPP1R2 protein phosphatase 1 regulatory inhibitor subunit 2 ISO RGD PMID:12270929 RGD:1299366 NCBI chr33:30,525,906...30,555,415
Ensembl chr33:30,525,906...30,555,415 		JBrowse link
G SENP2 SUMO specific peptidase 2 ISO Axin1 to Dvl1 RGD PMID:10944533 RGD:1299408 NCBI chr34:18,325,373...18,357,152
Ensembl chr34:18,325,553...18,356,192 		JBrowse link
negative regulation of receptor binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 ISO angiotensin receptor RGD PMID:24262995 RGD:39939015 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051 		JBrowse link
negative regulation of selenocysteine insertion sequence binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF4A3 eukaryotic translation initiation factor 4A3 ISO RGD PMID:19716792 RGD:10045552 NCBI chr 9:1,582,950...1,593,893
Ensembl chr 9:1,582,993...1,593,892 		JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30354218 RGD:124713558 NCBI chr 9:42,597,792...42,607,576
Ensembl chr 9:42,597,792...42,607,576 		JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KAT2B lysine acetyltransferase 2B ISO Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr23:23,166,722...23,242,447
Ensembl chr23:23,168,600...23,233,478 		JBrowse link
G KDM1A lysine demethylase 1A ISO RGD PMID:20418916 RGD:9588315 NCBI chr 2:76,313,742...76,375,716
Ensembl chr 2:76,156,434...76,375,632 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:25135974 RGD:9589119 NCBI chr 1:21,232,260...21,283,687
Ensembl chr 1:21,235,967...21,283,346 		JBrowse link
G MFN2 mitofusin 2 ISO Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr 4:62,170,137...62,268,962
Ensembl chr 4:62,170,452...62,268,983 		JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr 4:62,170,137...62,268,962
Ensembl chr 4:62,170,452...62,268,983 		JBrowse link
G JAK2 Janus kinase 2 ISO Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:12873812 RGD:10059626 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:11181516 RGD:2311195 NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16272348 RGD:1598594 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO RGD PMID:19057620 RGD:2311715 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131 		JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr27:6,993,452...7,030,372
Ensembl chr27:6,993,452...7,017,316 		JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21229611 RGD:10403032 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252 		JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO RGD PMID:19273590 RGD:9999430 NCBI chr 1:114,267,195...114,279,107
Ensembl chr 1:114,267,210...114,278,837 		JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724 		JBrowse link
G CALD1 caldesmon 1 ISO RGD PMID:3384851 RGD:2303065 NCBI chr16:13,087,419...13,279,648
Ensembl chr16:13,084,109...13,279,384 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO RGD PMID:11415446 RGD:4892111 NCBI chr11:21,290,603...21,363,701
Ensembl chr11:21,290,621...21,505,122 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:7908909 RGD:633201 NCBI chr 5:65,669,553...65,683,445 JBrowse link
G PACS1 phosphofurin acidic cluster sorting protein 1 ISO RGD PMID:9695949 RGD:633354 NCBI chr18:51,055,487...51,196,223
Ensembl chr18:51,056,429...51,196,102 		JBrowse link
G PLK2 polo like kinase 2 ISO Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr 2:45,359,865...45,365,496
Ensembl chr 2:45,360,374...45,367,441 		JBrowse link
G RAMP1 receptor activity modifying protein 1 ISO RGD PMID:11556887 RGD:1299115 NCBI chr25:48,431,136...48,466,070
Ensembl chr25:48,437,919...48,466,070 		JBrowse link
G RAMP2 receptor activity modifying protein 2 ISO RGD PMID:11556887 RGD:1299115 NCBI chr 9:20,250,711...20,252,485 JBrowse link
G TRIM28 tripartite motif containing 28 ISO RGD PMID:12748187 RGD:1299608 NCBI chr 1:99,408,920...99,415,432
Ensembl chr 1:99,408,925...99,415,146 		JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30726115 RGD:124713559 NCBI chr 9:42,597,792...42,607,576
Ensembl chr 9:42,597,792...42,607,576 		JBrowse link
regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARM1 coactivator associated arginine methyltransferase 1 ISO RGD PMID:22736542 RGD:9586719 NCBI chr20:50,328,466...50,371,845
Ensembl chr20:50,331,030...50,348,195 		JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 ISO Secisbp2 RGD PMID:19716792 RGD:10045552 NCBI chr 9:1,582,950...1,593,893
Ensembl chr 9:1,582,993...1,593,892 		JBrowse link
regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAN RAN, member RAS oncogene family ISO RGD PMID:9398662 RGD:9835011 NCBI chr26:1,435,077...1,436,893
Ensembl chr26:1,434,720...1,436,993 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:12385827 RGD:1579945 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of molecular function 305
        regulation of binding 44
          negative regulation of binding + 16
          positive regulation of binding + 27
          regulation of DNA binding + 11
          regulation of GTP binding + 6
          regulation of RNA binding + 3
          regulation of calcium ion binding + 0
          regulation of chromatin binding + 4
          regulation of collagen binding + 1
          regulation of ferrous iron binding + 0
          regulation of heparan sulfate binding + 0
          regulation of lipid binding + 0
          regulation of protein binding + 23
paths to the root