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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of binding
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Accession:GO:0051098 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


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negative regulation of cytokine activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO (PMID:9847016) RGD PMID:9847016 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nog noggin involved_in ISO (PMID:8752214) RGD PMID:8752214 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
negative regulation of DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac2 histone deacetylase 2 IMP RGD PMID:21383775 RGD:9590238 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP Rela RGD PMID:17473852 RGD:5688754 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Id1 inhibitor of DNA binding 1 IMP RGD PMID:7623812 RGD:9686118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Sirt1 sirtuin 1 IMP Rela RGD PMID:22044919 RGD:10047123 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
negative regulation of GTP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rap1gap Rap1 GTPase-activating protein IMP RGD PMID:19066305 RGD:9835342 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253 		JBrowse link
negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 involved_in ISO (PMID:11024022) RGD PMID:11024022 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
negative regulation of protein binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA beta-amyloid aggregation RGD PMID:14706557 RGD:2312790 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IMP RGD PMID:9553145 RGD:2303817 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Id1 inhibitor of DNA binding 1 IMP RGD PMID:23831032 RGD:9686139 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:20802490 RGD:152995511 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 IDA RGD PMID:12270929 RGD:1299366 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463 		JBrowse link
G Senp2 SUMO specific peptidase 2 IDA Axin1 to Dvl1 RGD PMID:10944533 RGD:1299408 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
negative regulation of protein homodimerization activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga4 integrin subunit alpha 4 involved_in ISO (PMID:12869515) RGD PMID:12869515 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
negative regulation of receptor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP angiotensin receptor RGD PMID:24262995 RGD:39939015 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 involved_in ISO (PMID:25588844) RGD PMID:25588844 NCBI chr19:33,477,750...33,506,424
Ensembl chr19:33,477,793...33,506,420 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23241886)
(PMID:25588844)		 UniProt
RGD		 PMID:23241886 PMID:25588844 GO_REF:0000024 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
negative regulation of selenocysteine insertion sequence binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4a3 eukaryotic translation initiation factor 4A3 IDA RGD PMID:19716792 RGD:10045552 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Poldip2 DNA polymerase delta interacting protein 2 IMP RGD PMID:30354218 RGD:124713558 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B IMP Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kdm1a lysine demethylase 1A IMP RGD PMID:20418916 RGD:9588315 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IMP RGD PMID:25135974 RGD:9589119 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mfn2 mitofusin 2 IMP Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 IMP epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:19057620 RGD:2311715 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Itga2 integrin subunit alpha 2 IMP DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Jak2 Janus kinase 2 IMP Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:12873812 RGD:10059626 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:11181516 RGD:2311195 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16272348 RGD:1598594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
positive regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tns3 tensin 3 involved_in ISO (PMID:27505886) RGD PMID:27505886 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998 		JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21229611 RGD:10403032 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpl heterogeneous nuclear ribonucleoprotein L IMP RGD PMID:19273590 RGD:9999430 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Cald1 caldesmon 1 IDA RGD PMID:3384851 RGD:2303065 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IDA RGD PMID:11415446 RGD:4892111 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta IDA RGD PMID:7908909 RGD:633201 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 IMP RGD PMID:9695949 RGD:633354 NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473 		JBrowse link
G Plk2 polo-like kinase 2 IDA Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ramp1 receptor activity modifying protein 1 IDA RGD PMID:11556887 RGD:1299115 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151 		JBrowse link
G Ramp2 receptor activity modifying protein 2 IDA RGD PMID:11556887 RGD:1299115 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Trim28 tripartite motif-containing 28 IDA RGD PMID:12748187 RGD:1299608 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epha4 Eph receptor A4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12775584)		 UniProt
RGD		 PMID:12775584 GO_REF:0000024 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 IDA RGD PMID:30726115 RGD:124713559 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
regulation of cytokine activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem2 gremlin 2, DAN family BMP antagonist involved_in ISO (PMID:23850456) RGD PMID:23850456 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615 		JBrowse link
regulation of growth hormone activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldoc1 LDOC1, regulator of NFKB signaling acts_upstream_of_or_within ISO MGI:5691781 (PMID:25468940) RGD PMID:25468940 NCBI chr  X:139,965,509...140,074,355
Ensembl chr  X:139,965,509...140,074,355 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 acts_upstream_of_or_within ISO MGI:2181542 (PMID:26476147) RGD PMID:26476147 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mia2 MIA SH3 domain ER export factor 2 NOT|involved_in ISO (PMID:25202031) RGD PMID:25202031 NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211 		JBrowse link
regulation of mRNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carm1 coactivator-associated arginine methyltransferase 1 IMP RGD PMID:22736542 RGD:9586719 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IDA Secisbp2 RGD PMID:19716792 RGD:10045552 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
regulation of protein binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ran RAN, member RAS oncogene family IDA RGD PMID:9398662 RGD:9835011 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:12385827 RGD:1579945 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
regulation of protein homodimerization activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip3 TRAF3 interacting protein 3 acts_upstream_of_or_within ISO MGI:5795738 (PMID:31390091) RGD PMID:31390091 NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673 		JBrowse link
regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccpg1 cell cycle progression 1 acts_upstream_of_or_within ISO (PMID:17000758) RGD PMID:17000758 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of molecular function 1784
        regulation of binding 59
          negative regulation of binding + 18
          positive regulation of binding + 34
          regulation of DNA binding + 11
          regulation of GTP binding + 15
          regulation of RNA binding + 3
          regulation of calcium ion binding + 0
          regulation of chromatin binding + 4
          regulation of collagen binding + 1
          regulation of ferrous iron binding + 0
          regulation of heparan sulfate binding + 0
          regulation of lipid binding + 0
          regulation of protein binding + 29
paths to the root