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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of DNA-binding transcription factor activity
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Accession:GO:0051090 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
Synonyms:exact_synonym: regulation of sequence-specific DNA binding transcription factor activity
 narrow_synonym: regulation of androgen receptor activity;   regulation of thyroid hormone receptor activity
 broad_synonym: regulation of transcription factor activity
 alt_id: GO:1904167;   GO:2000823


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regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:22275377 RGD:153297769 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha IMP RGD PMID:9918814 PMID:16580131 PMID:9343439 PMID:10620707 RGD:2298880, RGD:2298917, RGD:2298908, RGD:2298882 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbib NFKB inhibitor beta IMP RGD PMID:9343439 PMID:16580131 RGD:2298908, RGD:2298917 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
cytoplasmic sequestering of transcription factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 IMP RGD PMID:11439354 RGD:727319 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
negative regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 IDA RGD PMID:15829559 RGD:1599733 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
negative regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln1 egl-9 family hypoxia-inducible factor 1 IDA RGD PMID:20308610 RGD:6483365 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IDA STAT5b RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor IDA RGD PMID:11641275 RGD:1599577 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 IMP RGD PMID:12697699 RGD:1624302 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Rpl11 ribosomal protein L11 IDA RGD PMID:16280383 RGD:11035228 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Thra thyroid hormone receptor alpha IDA RGD PMID:2537467 RGD:1580107 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thra_v2 thyroid hormone receptor alpha, variant 2 IDA RGD PMID:2537467 RGD:1580107
positive regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D IMP RGD PMID:16706838 RGD:6906921 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
positive regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:19057620 RGD:2311715 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IDA RGD PMID:12371906 RGD:629541 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Hmga2 high mobility group AT-hook 2 IMP RGD PMID:9311991 RGD:1601604 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Jak2 Janus kinase 2 IMP Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 IDA RGD PMID:11713241 RGD:727330 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16272348 RGD:1598594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I IDA glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
positive regulation of NF-kappaB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone IMP RGD PMID:11356848 RGD:70295 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:9062344 RGD:1600239 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IMP RGD PMID:15939736 RGD:7495757 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:9062344 RGD:1600239 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Tgfb1 transforming growth factor, beta 1 IDA RGD PMID:15781474 RGD:1579751 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16651628 RGD:1598593 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 IMP RGD PMID:8982082 RGD:730027 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 IMP RGD PMID:10713108 RGD:2298798 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    biological regulation 13203
      regulation of molecular function 323
        regulation of DNA-binding transcription factor activity 30
          negative regulation of DNA-binding transcription factor activity + 12
          negative regulation of hh target transcription factor activity 0
          positive regulation of DNA-binding transcription factor activity + 17
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      cellular metabolic process 10142
        cellular aromatic compound metabolic process 5701
          nucleobase-containing compound metabolic process 5468
            nucleic acid metabolic process 4981
              RNA metabolic process 4384
                RNA biosynthetic process 3312
                  DNA-templated transcription 3289
                    regulation of DNA-templated transcription 3150
                      regulation of DNA-binding transcription factor activity 30
                        negative regulation of DNA-binding transcription factor activity + 12
                        negative regulation of hh target transcription factor activity 0
                        positive regulation of DNA-binding transcription factor activity + 17
paths to the root