Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA metabolic process
go back to main search page
Accession:GO:0051052 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
Synonyms:exact_synonym: regulation of DNA metabolism


show annotations for term's descendants           Sort by:
 
DNA hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO (MGI:5694015|PMID:25503965) MGI PMID:25503965 MGI:5694015 NCBI chr 3:106,091,990...106,251,790
Ensembl chr 3:113,021,874...113,180,331
JBrowse link
hypermethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (PMID:20139074) UniProt PMID:20139074 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
hypomethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5607719|PMID:20961378) MGI PMID:20961378 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DFFA DNA fragmentation factor subunit alpha acts_upstream_of_or_within ISO (MGI:2182584|PMID:10601318), (MGI:3029597|PMID:14663139)
(PMID:15572351)
MGI PMID:10601318 PMID:14663139 PMID:15572351 MGI:2182584 MGI:3029597 NCBI chr 1:9,221,096...9,232,813
Ensembl chr 1:10,445,553...10,457,547
JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 ISO RGD PMID:27184051 RGD:13781945 NCBI chr 1:8,712,798...8,753,027
Ensembl chr 1:9,942,491...9,982,364
JBrowse link
G PAM16 presequence translocase associated motor 16 ISO RGD PMID:24069394 RGD:13462066 NCBI chr16:3,257,769...3,278,322 JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DFFA DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) CAFA PMID:19944011 NCBI chr 1:9,221,096...9,232,813
Ensembl chr 1:10,445,553...10,457,547
JBrowse link
negative regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:12070119) UniProt PMID:12070119 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G ANKRD1 ankyrin repeat domain 1 involved_in ISO (PMID:11139470) BHF-UCL PMID:11139470 NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CHEK1 checkpoint kinase 1 ISO RGD PMID:12429946 RGD:2316115 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981
JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in ISO (PMID:16980615) CACAO PMID:16980615 NCBI chr13:52,666,569...53,098,257 JBrowse link
G DNAJC2 DnaJ heat shock protein family (Hsp40) member C2 acts_upstream_of_or_within ISO (MGI:76992|PMID:7559602) MGI PMID:7559602 MGI:76992 NCBI chr 7:95,303,823...95,336,085
Ensembl chr 7:108,048,307...108,080,127
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:10446064 RGD:7771571 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G GDF2 growth differentiation factor 2 involved_in ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr10:46,520,808...46,526,414 JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:14702389 RGD:8662403 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:23271285 RGD:9831181 NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840
JBrowse link
G NIBAN2 niban apoptosis regulator 2 involved_in ISO (PMID:14602737), (PMID:17569660), (PMID:20032057) UniProt PMID:14602737 PMID:17569660 PMID:20032057 NCBI chr 9:98,625,411...98,689,077
Ensembl chr 9:127,299,475...127,371,459
JBrowse link
G NPPC natriuretic peptide C ISO RGD PMID:12746286 RGD:1580115 NCBI chr2B:119,148,774...119,153,381
Ensembl chr2B:237,936,939...237,941,244
JBrowse link
G RGN regucalcin ISO RGD PMID:11500948 RGD:9590199 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:11502571 RGD:70312 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of DNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:2001740 RGD:9590215 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr12:7,834,298...7,841,064 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) MGI PMID:15087456 MGI:3046385 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G TRIM28 tripartite motif containing 28 acts_upstream_of_or_within ISO (MGI:5319411|PMID:22495301) MGI PMID:22495301 MGI:5319411 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144
JBrowse link
negative regulation of DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SUB1 SUB1 regulator of transcription involved_in ISO (PMID:28369605) CACAO PMID:28369605 NCBI chr 5:77,728,309...77,800,534
Ensembl chr 5:83,112,131...83,130,755
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr21:30,503,194...30,520,237 JBrowse link
G KMT2A lysine methyltransferase 2A involved_in ISO (PMID:20010842) UniProt PMID:20010842 NCBI chr11:113,273,198...113,364,404 JBrowse link
negative regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in ISO (PMID:9671747) UniProt PMID:9671747 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G LIG3 DNA ligase 3 acts_upstream_of_or_within ISO (MGI:3625660|PMID:16648486) MGI PMID:16648486 MGI:3625660 NCBI chr17:21,776,483...21,805,706
Ensembl chr17:22,074,046...22,095,220
JBrowse link
G MSH2 mutS homolog 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17715146)
(MGI:1351797|PMID:10545954), (MGI:74950|PMID:7628020)
BHF-UCL
MGI
PMID:7628020 PMID:10545954 PMID:17715146 MGI:1351797 MGI:74950 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MSH3 mutS homolog 3 involved_in ISO (PMID:17715146) BHF-UCL PMID:17715146 NCBI chr 5:34,408,469...34,663,483
Ensembl chr 5:34,719,322...34,938,469
JBrowse link
G MSH6 mutS homolog 6 involved_in
acts_upstream_of_or_within
ISO (PMID:17715146)
(MGI:1351797|PMID:10545954)
BHF-UCL
MGI
PMID:10545954 PMID:17715146 MGI:1351797 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G RAD18 RAD18 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (MGI:2448116|PMID:12509447) MGI PMID:12509447 MGI:2448116 NCBI chr 3:8,832,910...8,918,067
Ensembl chr 3:9,076,500...9,161,585
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558) UniProt PMID:22704558 NCBI chr2B:24,331,731...24,665,652
Ensembl chr2B:139,234,909...139,577,193
JBrowse link
negative regulation of DNA recombination at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERF2IP TERF2 interacting protein involved_in ISO (MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869) UniProt PMID:20339076 PMID:20622869 MGI:4440768 MGI:4839412 NCBI chr16:56,216,920...56,226,612
Ensembl chr16:75,565,184...75,573,882
JBrowse link
negative regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPS3 ribosomal protein S3 involved_in ISO (PMID:17049931) UniProt PMID:17049931 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
negative regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 involved_in ISO (PMID:20725033) UniProt PMID:20725033 NCBI chr11:59,342,820...59,355,386
Ensembl chr11:62,690,542...62,706,542
JBrowse link
G RNF169 ring finger protein 169 involved_in ISO (PMID:22492721), (PMID:22733822)
(PMID:22742833)
UniProt PMID:22492721 PMID:22733822 PMID:22742833 NCBI chr11:69,821,842...69,909,297
Ensembl chr11:73,126,127...73,207,340
JBrowse link
G TRIP12 thyroid hormone receptor interactor 12 involved_in ISO (PMID:22884692) UniProt PMID:22884692 NCBI chr2B:117,013,343...117,175,296
Ensembl chr2B:235,820,182...235,979,780
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) BHF-UCL PMID:17690110 NCBI chr 7:19,761,041...19,765,665 JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO (PMID:22884692) UniProt PMID:22884692 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913
JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in ISO (PMID:30356214)
(MGI:6241455|PMID:30356214)
UniProt PMID:30356214 MGI:6241455 NCBI chr 6:71,252,050...71,279,121
Ensembl chr 6:74,544,251...74,566,965
JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr  X:7,470,574...7,500,958
Ensembl chr  X:14,752,934...14,781,817
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in ISO (PMID:19736316)
(MGI:5566975|PMID:24108124)
UniProt PMID:19736316 PMID:24108124 MGI:5566975 NCBI chr10:5,931,389...5,978,844
Ensembl chr10:5,915,713...5,962,778
JBrowse link
G HELB DNA helicase B involved_in ISO (PMID:26774285)
(MGI:5766842|PMID:26774285)
UniProt PMID:26774285 MGI:5766842 NCBI chr12:22,571,448...22,607,417
Ensembl chr12:23,078,732...23,114,134
JBrowse link
G KLHL15 kelch like family member 15 involved_in ISO (PMID:27561354) UniProt PMID:27561354 NCBI chr  X:16,583,117...16,625,029
Ensembl chr  X:23,956,827...23,997,742
JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G MAGEF1 MAGE family member F1 involved_in ISO (PMID:29225034) UniProt PMID:29225034 NCBI chr 3:181,750,186...181,751,900
Ensembl chr 3:190,229,865...190,230,791
JBrowse link
G PARPBP PARP1 binding protein involved_in ISO (PMID:22153967) UniProt PMID:22153967 NCBI chr12:99,707,641...99,784,993
Ensembl chr12:103,105,117...103,182,366
JBrowse link
G POLQ DNA polymerase theta involved_in ISO (PMID:25642963)
(MGI:5621198|PMID:25642960)
UniProt PMID:25642960 PMID:25642963 MGI:5621198 NCBI chr 3:118,535,968...118,648,275
Ensembl chr 3:125,446,829...125,559,283
JBrowse link
G RADX RPA1 related single stranded DNA binding protein, X-linked involved_in ISO (PMID:28735897) UniProt PMID:28735897 NCBI chr  X:95,714,600...95,781,853
Ensembl chr  X:106,092,340...106,159,772
JBrowse link
G RECQL5 RecQ like helicase 5 acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr17:69,577,778...69,618,068
Ensembl chr17:75,128,325...75,168,254
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISO (PMID:23333306)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
UniProt PMID:23306437 PMID:23333305 PMID:23333306 MGI:5468037 MGI:5476381 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) UniProt PMID:25294876 NCBI chr18:11,479,742...11,627,035
Ensembl chr18:13,785,912...13,933,887
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23345425)
(MGI:5476381|PMID:23333305)
(MGI:5887194|PMID:20362325)
UniProt PMID:20362325 PMID:23333305 PMID:23333306 PMID:23345425 MGI:5476381 MGI:5887194 NCBI chr15:22,364,696...22,472,499
Ensembl chr15:40,519,012...40,626,741
JBrowse link
G UBQLN4 ubiquilin 4 involved_in ISO (PMID:30612738) UniProt PMID:30612738 NCBI chr 1:131,374,635...131,395,986
Ensembl chr 1:135,209,490...135,225,666
JBrowse link
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AUNIP aurora kinase A and ninein interacting protein involved_in ISO (PMID:29042561) UniProt PMID:29042561 NCBI chr 1:25,090,690...25,118,062
Ensembl chr 1:26,157,953...26,185,578
JBrowse link
G CYREN cell cycle regulator of NHEJ involved_in ISO (PMID:28959974) UniProt PMID:28959974 NCBI chr 7:127,130,587...127,148,824 JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) UniProt PMID:25820262 NCBI chr10:44,703,720...44,784,948 JBrowse link
G HMGA2 high mobility group AT-hook 2 involved_in ISO (PMID:19549901) UniProt PMID:19549901 NCBI chr12:22,954,946...23,096,623 JBrowse link
G HSF1 heat shock transcription factor 1 involved_in ISO (PMID:26359349) UniProt PMID:26359349 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G NUDT16L1 nudix hydrolase 16 like 1 involved_in ISO (PMID:28241136) UniProt PMID:28241136 NCBI chr16:3,615,841...3,620,526
Ensembl chr16:4,785,358...4,786,775
JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OGG1 8-oxoguanine DNA glycosylase acts_upstream_of_or_within ISO (PMID:19506022) MGI PMID:19506022 NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GZMA granzyme A involved_in ISO (PMID:12524539) UniProt PMID:12524539 NCBI chr 5:58,919,129...58,926,620
Ensembl chr 5:60,540,988...60,548,506
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (MGI:6214451|PMID:26000965) UniProt PMID:26000965 MGI:6214451 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G THOC1 THO complex 1 involved_in ISO (MGI:5520039|PMID:22144908) UniProt PMID:22144908 MGI:5520039 NCBI chr18:14,052,858...14,102,559
Ensembl chr18:17,692,797...17,742,570
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within ISO (MGI:1345885|PMID:10490661) MGI PMID:10490661 MGI:1345885 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:3695768|PMID:16275384) MGI PMID:16275384 MGI:3695768 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913
JBrowse link
negative regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLCN folliculin involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
negative regulation of mitotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 involved_in ISO (MGI:5800654|PMID:27010503) UniProt PMID:27010503 MGI:5800654 NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070
JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within
involved_in
ISO (MGI:1312959|PMID:9808625), (MGI:3655554|PMID:16914751)
(MGI:5800654|PMID:27010503)
(MGI:1928200|PMID:11101838)
(MGI:3700903|PMID:17210642)
MGI
UniProt
PMID:9808625 PMID:11101838 PMID:16914751 PMID:17210642 PMID:27010503 MGI:1312959 MGI:1928200 MGI:3655554 MGI:3700903 MGI:5800654 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G MLH1 mutL homolog 1 acts_upstream_of_or_within ISO (MGI:3513725|PMID:15480418) MGI PMID:15480418 MGI:3513725 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) BHF-UCL PMID:14690602 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) BHF-UCL PMID:14690602 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) BHF-UCL PMID:14690602 MGI:3758502 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
G XRCC4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602) BHF-UCL PMID:14690602 MGI:3758502 NCBI chr 5:31,927,463...32,202,394
Ensembl chr 5:32,246,320...32,521,490
JBrowse link
negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:25620558)
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)
BHF-UCL PMID:22579284 PMID:24115439 PMID:25620558 MGI:5522574 MGI:5645200
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) BHF-UCL PMID:15507207 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) BHF-UCL PMID:19581589 NCBI chr2B:103,371,459...103,468,419
Ensembl chr2B:221,972,742...222,071,235
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS1 ceramide synthase 1 involved_in ISO (PMID:17548428) UniProt PMID:17548428 NCBI chr19:18,308,265...18,334,892 JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit NOT|involved_in ISO (PMID:18812185) BHF-UCL PMID:18812185 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G MCRS1 microspherule protein 1 involved_in ISO (PMID:15044100) BHF-UCL PMID:15044100 NCBI chr12:39,183,112...39,192,925
Ensembl chr12:40,073,860...40,083,655
JBrowse link
G MEN1 menin 1 involved_in ISO (PMID:12837246) UniProt PMID:12837246 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649) HGNC-UCL PMID:16522649 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:11701125)
(PMID:11701125), (PMID:21119197)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr 8:8,366,819...8,443,359 JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:15632080) BHF-UCL PMID:15632080 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO RGD PMID:16556873 RGD:1580657 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr 8:69,545,115...69,583,997 JBrowse link
G TP53 tumor protein p53 involved_in ISO (PMID:10597287) BHF-UCL PMID:10597287 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (PMID:24528514) BHF-UCL PMID:24528514 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
negative regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in ISO (PMID:17694070) BHF-UCL PMID:17694070 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G NBN nibrin involved_in ISO (PMID:17694070) BHF-UCL PMID:17694070 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in ISO (PMID:17694070) BHF-UCL PMID:17694070 NCBI chr 5:127,972,630...128,059,911 JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12676087) BHF-UCL PMID:12676087 NCBI chr17:2,050,825...2,294,892
Ensembl chr17:1,937,630...2,179,535
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:24270157) BHF-UCL PMID:24270157 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
negative regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:17055345) UniProt PMID:17055345 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:17055345) UniProt PMID:17055345 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345) UniProt PMID:17055345 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 acts_upstream_of_or_within ISO (MGI:2656398|PMID:12676566) MGI PMID:12676566 MGI:2656398 NCBI chr14:5,015,862...5,019,228
Ensembl chr14:23,139,445...23,142,825
JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207)
(MGI:5883205|PMID:24120135)
BHF-UCL PMID:15507207 PMID:24120135 MGI:5883205 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:15181449)
(PMID:15380063)
BHF-UCL PMID:15181449 PMID:15380063 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:43,410,385...43,433,784
Ensembl chr17:48,142,864...48,165,537
JBrowse link
G DCP2 decapping mRNA 2 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 5:108,333,091...108,377,119
Ensembl chr 5:114,144,999...114,172,480
JBrowse link
G EXOSC10 exosome component 10 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 1:9,829,922...9,865,092
Ensembl chr 1:11,050,727...11,087,241
JBrowse link
G GNL3L G protein nucleolar 3 like involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:46,733,431...46,825,139
Ensembl chr  X:54,966,121...55,002,925
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr14:2,022,280...2,083,215 JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031
JBrowse link
G NAT10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr11:34,082,304...34,127,793
Ensembl chr11:33,960,739...34,002,069
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:21119197)
(PMID:11701125)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr 8:8,366,819...8,443,359 JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:15181449) BHF-UCL PMID:15181449 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G STN1 STN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr10:100,456,589...100,518,010
Ensembl chr10:103,942,422...103,977,847
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:69,928,204...69,947,138 JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr16:30,415,668...30,494,758
Ensembl chr16:49,299,498...49,373,665
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr 8:69,545,115...69,583,997 JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:17055345 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025)
(PMID:15133513)
BHF-UCL PMID:10581025 PMID:15133513 NCBI chr14:5,015,862...5,019,228
Ensembl chr14:23,139,445...23,142,825
JBrowse link
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:18812185) BHF-UCL PMID:18812185 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G MCRS1 microspherule protein 1 involved_in ISO (PMID:15044100) BHF-UCL PMID:15044100 NCBI chr12:39,183,112...39,192,925
Ensembl chr12:40,073,860...40,083,655
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) BHF-UCL PMID:24012755
G SLX4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) BHF-UCL PMID:24012755 NCBI chr16:2,502,334...2,532,172
Ensembl chr16:3,678,018...3,707,842
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:24012755) BHF-UCL PMID:24012755 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G TNKS tankyrase involved_in ISO (PMID:25939383) BHF-UCL PMID:25939383 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G TNKS2 tankyrase 2 involved_in ISO (PMID:25939383) BHF-UCL PMID:25939383 NCBI chr10:88,547,396...88,612,973
Ensembl chr10:92,070,362...92,134,911
JBrowse link
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:15200954) BHF-UCL PMID:15200954 NCBI chr 8:69,545,115...69,583,997 JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) BHF-UCL PMID:15200954 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
negative regulation of transposon integration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF93 zinc finger protein 93 involved_in ISO (PMID:25274305) UniProt PMID:25274305 NCBI chr19:19,302,147...19,370,488 JBrowse link
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:11350920) BHF-UCL PMID:11350920 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G ENDOG endonuclease G ISO RGD PMID:16407272 RGD:9685355 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21192280 RGD:10403035 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:15125883 RGD:10402776 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chr 7:23,415,922...23,420,767 JBrowse link
positive regulation of base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM168A family with sequence similarity 168 member A involved_in ISO (PMID:25260657) UniProt PMID:25260657 NCBI chr11:68,477,579...68,674,428
Ensembl chr11:71,698,901...71,766,921
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:19443450) UniProt PMID:19443450 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO RGD PMID:19254952 RGD:5509898 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G C3AR1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16005543 RGD:5131269 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:20439821 RGD:7829726 NCBI chr2A:38,087,863...38,096,529
Ensembl chr2A:38,851,000...38,859,824
JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:22446327 RGD:10401140 NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569
JBrowse link
G FGF2 fibroblast growth factor 2 involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in ISO (PMID:21653700) UniProt PMID:21653700 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605
JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:16937468 RGD:9685728 NCBI chr16:716,640...720,196
Ensembl chr16:2,073,064...2,076,592
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:12721208 RGD:10045365 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G HGF hepatocyte growth factor involved_in ISO (PMID:2531289) UniProt PMID:2531289 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:9924025) UniProt PMID:9924025 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) UniProt PMID:17942966 MGI:5009390 NCBI chr11:84,330,362...84,496,755 JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 ISO RGD PMID:12890786 RGD:7775030 NCBI chr  X:100,060,647...100,345,491
Ensembl chr  X:110,672,664...110,797,992
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919) UniProt PMID:10644978 PMID:10734101 PMID:11788434 PMID:12070119 PMID:16530387 PMID:17942966 PMID:19019919 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISO (MGI:5284758|PMID:19019919) UniProt PMID:19019919 MGI:5284758 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (MGI:5306299|PMID:17226786) UniProt PMID:17226786 MGI:5306299 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:21451101 RGD:10041071 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G RGCC regulator of cell cycle involved_in ISO PMID:9756947 BHF-UCL PMID:9756947 RGD:633887 NCBI chr13:22,639,289...22,652,594
Ensembl chr13:41,228,643...41,241,909
JBrowse link
G SMOC2 SPARC related modular calcium binding 2 involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 6:166,430,178...166,664,577
Ensembl chr 6:171,366,929...171,589,084
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9395232 RGD:14696805 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
positive regulation of DNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO RGD PMID:27895165 RGD:12879393 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUD4 OTU deubiquitinase 4 involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr 4:137,480,809...137,527,651
Ensembl chr 4:149,135,900...149,182,476
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in ISO (MGI:5762940|PMID:23560077) UniProt PMID:23560077 MGI:5762940 NCBI chr2A:47,201,536...47,271,253
Ensembl chr2A:48,131,547...48,199,596
JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in ISO (MGI:3045816|PMID:15078895) UniProt PMID:15078895 MGI:3045816 NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr  X:33,535,543...33,683,220
Ensembl chr  X:41,232,041...41,379,910
JBrowse link
positive regulation of DNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:9600082) CACAO PMID:9600082 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403) UniProt PMID:28002403 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
positive regulation of DNA ligation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chr2A:68,509,314...68,629,192
Ensembl chr2A:69,632,459...69,744,611
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO PMID:10866811 UniProt PMID:10866811 RGD:10449519 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
G RAD51 RAD51 recombinase involved_in ISO (PMID:8929543) UniProt PMID:8929543 NCBI chr15:19,638,310...19,672,474
Ensembl chr15:37,891,056...37,925,207
JBrowse link
positive regulation of DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA3 annexin A3 ISO RGD PMID:15744063 RGD:2316072 NCBI chr 4:45,585,873...45,644,783
Ensembl chr 4:51,432,846...51,491,677
JBrowse link
G HMGB2 high mobility group box 2 ISO RGD PMID:8432381 RGD:2316096 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:19507001 RGD:2311507 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:11481036 RGD:1600909 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 ISO lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr 8:21,268,873...21,281,684
Ensembl chr 8:18,208,934...18,221,577
JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:19139380 RGD:2305938 NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479
JBrowse link
G PFN1 profilin 1 ISO RGD PMID:10966486 RGD:2324858 NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022
JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr21:30,503,194...30,520,237 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19786833) BHF-UCL PMID:19786833 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G WT1 WT1 transcription factor acts_upstream_of ISO (PMID:23042785) ARUK-UCL PMID:23042785 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
positive regulation of DNA primase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRIM2 DNA primase subunit 2 involved_in ISO (PMID:25550159) UniProt PMID:25550159 NCBI chr 6:56,875,331...56,884,118 JBrowse link
positive regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335) ARUK-UCL PMID:31453335 MGI:6358520 NCBI chr 7:92,429,776...92,457,943
Ensembl chr 7:105,832,031...105,859,995
JBrowse link
positive regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chr 4:40,711,139...40,736,763
Ensembl chr 4:46,556,892...46,581,573
JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 involved_in ISO PMID:19282473
(MGI:3698695|PMID:17121854)
UniProt PMID:17121854 PMID:19282473 MGI:3698695 RGD:8553580 NCBI chr11:6,526,477...6,550,509
Ensembl chr11:6,209,812...6,225,972
JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProt PMID:19261746 PMID:19261748 PMID:19261749 NCBI chr19:16,755,518...16,767,634
Ensembl chr19:17,729,568...17,742,447
JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748) UniProt PMID:19261748 NCBI chr2A:27,884,907...28,338,302
Ensembl chr2A:27,974,917...28,420,519
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chr  X:144,550,320...144,592,795
Ensembl chr  X:154,389,283...154,428,669
JBrowse link
G CBX8 chromobox 8 ISO RGD PMID:23572236 RGD:9586727 NCBI chr17:73,874,618...73,877,347
Ensembl chr17:79,410,967...79,413,691
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma involved_in ISO (PMID:16255782) UniProt PMID:16255782 NCBI chr19:30,295,603...30,304,984
Ensembl chr19:39,046,219...39,046,671
JBrowse link
G DHX9 DExH-box helicase 9 involved_in ISO (PMID:24049074) UniProt PMID:24049074 NCBI chr 1:158,355,472...158,404,178
Ensembl chr 1:162,006,822...162,055,833
JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO (PMID:17115032) UniProt PMID:17115032 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:22483866) UniProt PMID:22483866 NCBI chr10:44,703,720...44,784,948 JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:7664335) UniProt PMID:7664335 NCBI chr 5:53,053,712...53,131,563
Ensembl chr 5:54,693,987...54,765,496
JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829
JBrowse link
G EYA3 EYA transcriptional coactivator and phosphatase 3 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chr 1:27,230,623...27,349,355
Ensembl chr 1:28,270,116...28,386,878
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in ISO (PMID:14975937) UniProt PMID:14975937 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase ISO RGD PMID:1945835 RGD:729332 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G NPAS2 neuronal PAS domain protein 2 involved_in ISO (PMID:18819933) UniProt PMID:18819933 Ensembl chr2A:101,868,933...101,972,866 JBrowse link
G PARG poly(ADP-ribose) glycohydrolase ISO RGD PMID:15158362 RGD:2316739 NCBI chr10:44,290,391...44,420,184 JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G RNF168 ring finger protein 168 involved_in ISO (PMID:23760478)
(PMID:19203578), (PMID:19203579)
UniProt PMID:19203578 PMID:19203579 PMID:23760478 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687
JBrowse link
G RNF8 ring finger protein 8 involved_in ISO (PMID:18001824), (PMID:18001825) UniProt PMID:18001824 PMID:18001825 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:23911537) UniProt PMID:23911537 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:19934257) UniProt PMID:19934257 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:24790221) UniProt PMID:24790221 NCBI chr18:11,479,742...11,627,035
Ensembl chr18:13,785,912...13,933,887
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TMEM161A transmembrane protein 161A involved_in ISO (PMID:16551573) BHF-UCL PMID:16551573 NCBI chr19:18,557,799...18,576,722
Ensembl chr19:19,560,046...19,578,779
JBrowse link
G TRIM28 tripartite motif containing 28 involved_in ISO (PMID:17178852) UniProt PMID:17178852 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:16129784) HGNC-UCL PMID:16129784 NCBI chr12:90,951,446...90,984,075 JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:44,435,496...44,488,517
Ensembl chr 8:41,856,429...41,878,320
JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chr 5:172,205,958...172,321,758
Ensembl chr 5:179,271,577...179,374,229
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of DNA strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POT1 protection of telomeres 1 involved_in ISO (PMID:16043710) BHF-UCL PMID:16043710 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (MGI:4439421|PMID:20215406) MGI PMID:20215406 MGI:4439421 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945
JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (MGI:3513706|PMID:15585571)
(MGI:4439421|PMID:20215406)
MGI PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 9:99,282,821...99,325,404
Ensembl chr 9:127,956,915...127,982,449
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) UniProt PMID:12930902 Ensembl chr16:803,340...813,170 JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr16:49,489,176...49,503,736
Ensembl chr16:68,877,028...68,891,513
JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr 8:116,524,249...116,546,178
Ensembl chr 8:119,272,490...119,294,342
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr17:58,574,442...58,593,915
Ensembl chr17:63,667,246...63,686,503
JBrowse link
G RFC2 replication factor C subunit 2 involved_in ISO (PMID:12930902) UniProt PMID:12930902 Ensembl chr 7:81,378,937...81,401,937 JBrowse link
G RFC3 replication factor C subunit 3 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr13:15,073,464...15,220,646
Ensembl chr13:33,503,439...33,523,403
JBrowse link
G RFC4 replication factor C subunit 4 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr 3:183,824,865...183,841,895
Ensembl chr 3:192,290,639...192,307,839
JBrowse link
G RFC5 replication factor C subunit 5 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr12:115,595,398...115,611,442
Ensembl chr12:118,973,560...118,990,308
JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:23797032) UniProt PMID:23797032 NCBI chr12:55,176,165...55,207,123 JBrowse link
G FMN2 formin 2 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr 1:215,626,889...216,023,590 JBrowse link
G FOXM1 forkhead box M1 involved_in ISO (PMID:17101782)
(MGI:3698692|PMID:17101782)
UniProt PMID:17101782 MGI:3698692 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731) UniProt PMID:29125140 PMID:33115731 MGI:6467697 MGI:6716977 NCBI chr 6:71,089,817...71,190,700
Ensembl chr 6:74,478,303...74,479,826
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase involved_in ISO (PMID:24147153) BHF-UCL PMID:24147153 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 6:71,195,619...71,197,040
Ensembl chr 6:74,484,764...74,511,331
JBrowse link
G SLF1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) UniProt PMID:25931565 NCBI chr 5:20,660,101...20,757,072
Ensembl chr 5:20,817,614...20,884,453
JBrowse link
G SLF2 SMC5-SMC6 complex localization factor 2 involved_in ISO (PMID:25931565) UniProt PMID:25931565 NCBI chr10:97,511,398...97,566,386
Ensembl chr10:100,989,044...101,042,730
JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in ISO (PMID:23509288) UniProt PMID:23509288 NCBI chr 8:43,691,454...44,166,259
Ensembl chr 8:41,083,964...41,558,170
JBrowse link
G SPIRE1 spire type actin nucleation factor 1 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr18:1,663,614...1,881,357
Ensembl chr18:16,800,870...16,992,959
JBrowse link
G SPIRE2 spire type actin nucleation factor 2 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr16:70,580,030...70,634,143
Ensembl chr16:90,273,160...90,299,061
JBrowse link
G TIMELESS timeless circadian regulator involved_in ISO (PMID:23797032) UniProt PMID:23797032 NCBI chr12:32,465,529...32,497,581
Ensembl chr12:32,718,649...32,750,728
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:27715493) UniProt PMID:27715493 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) ARUK-UCL PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr 7:92,429,776...92,457,943
Ensembl chr 7:105,832,031...105,859,995
JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ARID2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) CACAO PMID:28381560 NCBI chr12:42,823,236...43,004,465
Ensembl chr12:43,692,914...43,871,564
JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) UniProt PMID:25820262 NCBI chr10:44,703,720...44,784,948 JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr  X:7,470,574...7,500,958
Ensembl chr  X:14,752,934...14,781,817
JBrowse link
G FUS FUS RNA binding protein involved_in ISO (PMID:10567410) UniProt PMID:10567410 NCBI chr16:23,775,389...23,786,881
Ensembl chr16:31,551,135...31,562,327
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (PMID:31609975)
(MGI:6716962|PMID:25936915)
UniProt PMID:25936915 PMID:31609975 MGI:6716962 NCBI chr 6:71,089,817...71,190,700
Ensembl chr 6:74,478,303...74,479,826
JBrowse link
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in ISO (PMID:29225034) UniProt PMID:29225034 NCBI chr10:94,080,690...94,120,811
Ensembl chr10:97,574,257...97,614,146
JBrowse link
G MRNIP MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chr 5:174,989,967...175,020,550
Ensembl chr 5:182,299,016...182,340,632
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) UniProt PMID:29955025 MGI:6272426 NCBI chr 6:71,195,619...71,197,040
Ensembl chr 6:74,484,764...74,511,331
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098 PMID:30356214 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) UniProt PMID:17996710 PMID:17996711 NCBI chr12:4,657,972...4,679,232
Ensembl chr12:4,578,621...4,599,879
JBrowse link
G TIMELESS timeless circadian regulator involved_in ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098 PMID:30356214 NCBI chr12:32,465,529...32,497,581
Ensembl chr12:32,718,649...32,750,728
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380
JBrowse link
G WDR48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) UniProt PMID:27239033 PMID:27463890 NCBI chr 3:38,948,440...38,992,872
Ensembl chr 3:39,228,920...39,273,300
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DTX3L deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chr 3:119,654,019...119,664,918
Ensembl chr 3:126,558,924...126,569,807
JBrowse link
G FH fumarate hydratase involved_in ISO (PMID:26237645) UniProt PMID:26237645 NCBI chr 1:217,059,847...217,081,795
Ensembl chr 1:222,041,142...222,064,212
JBrowse link
G KDM4D lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) MGI PMID:24550317 NCBI chr11:89,987,537...90,013,421 JBrowse link
G KMT5B lysine methyltransferase 5B involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr11:63,239,796...63,297,113
Ensembl chr11:66,549,230...66,581,475
JBrowse link
G KMT5C lysine methyltransferase 5C involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr19:52,381,963...52,390,507
Ensembl chr19:61,073,396...61,078,717
JBrowse link
G LOC100986203 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20620605), (PMID:21491884) UniProt PMID:20620605 PMID:21491884 NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791
JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (PMID:24598253) UniProt PMID:24598253 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chr 3:119,617,722...119,655,039
Ensembl chr 3:126,522,859...126,559,647
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:12032095) CACAO PMID:12032095 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:26237645) UniProt PMID:26237645 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISO (PMID:28241136)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
UniProt
CACAO
PMID:23306437 PMID:23333305 PMID:28241136 MGI:5468037 MGI:5476381 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893), (PMID:29789392) UniProt PMID:29656893 PMID:29789392 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) UniProt PMID:25294876 NCBI chr18:11,479,742...11,627,035
Ensembl chr18:13,785,912...13,933,887
JBrowse link
G TOP2B DNA topoisomerase II beta ISO RGD PMID:22019940 RGD:13432143 NCBI chr 3:25,499,239...25,566,029
Ensembl chr 3:25,828,879...25,896,912
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:20605787) UniProt PMID:20605787 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:18499658) UniProt PMID:18499658 NCBI chr12:55,176,165...55,207,123 JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:19059439) UniProt PMID:19059439 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) MGI PMID:21255825 MGI:5009766 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chr 3:126,339,758...126,367,166
Ensembl chr 3:133,694,676...133,721,519
JBrowse link
G KMT5B lysine methyltransferase 5B involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr11:63,239,796...63,297,113
Ensembl chr11:66,549,230...66,581,475
JBrowse link
G KMT5C lysine methyltransferase 5C involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr19:52,381,963...52,390,507
Ensembl chr19:61,073,396...61,078,717
JBrowse link
G LOC100970806 exosome complex component MTR3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) MGI PMID:21255825 MGI:5009766 NCBI chr 7:140,163,275...140,176,732 JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G TFRC transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
(PMID:23760478)
UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr15:22,364,696...22,472,499
Ensembl chr15:40,519,012...40,626,741
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) MGI PMID:23241889 MGI:5462481 NCBI chr 4:2,009,276...2,119,182
Ensembl chr 4:1,945,307...2,027,425
JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNFSF13 TNF superfamily member 13 acts_upstream_of_or_within ISO (MGI:3037416|PMID:14988498)
(PMID:14988498)
MGI PMID:14988498 MGI:3037416 NCBI chr17:7,589,931...7,593,527
Ensembl chr17:7,576,465...7,579,834
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCF1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chr11:62,722,611...62,734,279 JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3037416|PMID:14988498) MGI PMID:14988498 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (MGI:5763555|PMID:25404367) MGI PMID:25404367 MGI:5763555 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within ISO (MGI:62368|PMID:7688139) MGI PMID:7688139 MGI:62368 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within ISO (MGI:87443|PMID:1830926) MGI PMID:1830926 MGI:87443 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498) MGI PMID:12882831 PMID:14988498 MGI:2670820 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 Ensembl chr16:30,186,326...30,190,654 JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:85031|PMID:9015183) MGI PMID:9015183 MGI:85031 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G TBX21 T-box transcription factor 21 acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
positive regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC10 histone deacetylase 10 involved_in ISO (PMID:26221039) UniProt PMID:26221039 NCBI chr22:30,473,753...30,481,369
Ensembl chr22:49,473,369...49,479,216
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:15014079) UniProt PMID:15014079 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G PRKCG protein kinase C gamma involved_in ISO (PMID:15808853) HGNC-UCL PMID:15808853 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977
JBrowse link
positive regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRDM9 PR/SET domain 9 acts_upstream_of_or_within ISO (MGI:4452589|PMID:20044538), (MGI:5306625|PMID:22028627)
(PMID:21750151)
MGI PMID:20044538 PMID:21750151 PMID:22028627 MGI:4452589 MGI:5306625 NCBI chr 5:86,847,131...86,856,802
Ensembl chr 5:92,377,523...92,395,486
JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in ISO (PMID:17996711) UniProt PMID:17996711 NCBI chr12:4,657,972...4,679,232
Ensembl chr12:4,578,621...4,599,879
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B acts_upstream_of_or_within ISO (MGI:2450033|PMID:12556476) MGI PMID:12556476 MGI:2450033 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:28002403)
(MGI:5902647|PMID:28002403)
UniProt PMID:28002403 MGI:5902647 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403)
(MGI:5902647|PMID:28002403)
UniProt PMID:28002403 MGI:5902647 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
positive regulation of strand invasion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRN WRN RecQ like helicase involved_in ISO (PMID:26420422) BHF-UCL PMID:26420422 NCBI chr 8:30,353,643...30,492,978
Ensembl chr 8:27,541,145...27,679,855
JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
G SLX4 SLX4 structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200 NCBI chr16:2,502,334...2,532,172
Ensembl chr16:3,678,018...3,707,842
JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25467444)
(MGI:3047190|PMID:15240872)
BHF-UCL
MGI
PMID:15240872 PMID:25467444 MGI:3047190 NCBI chr  X:144,243,493...144,257,419
Ensembl chr  X:154,084,412...154,098,475
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16545136) BHF-UCL PMID:16545136 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in ISO (PMID:19015635), (PMID:20938050) UniProt PMID:19015635 PMID:20938050 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G KLF4 Kruppel like factor 4 involved_in ISO (PMID:20629177) BHF-UCL PMID:20629177 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5810267|PMID:9637678) BHF-UCL PMID:9637678 MGI:5810267 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO (PMID:27510903) BHF-UCL PMID:27510903 NCBI chr 4:155,383,245...155,425,479
Ensembl chr 4:167,157,770...167,214,065
JBrowse link
G NEK2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G NVL nuclear VCP like involved_in ISO (PMID:22226966) UniProt PMID:22226966 NCBI chr 1:199,695,388...199,798,080
Ensembl chr 1:204,704,371...204,806,959
JBrowse link
G PARM1 prostate androgen-regulated mucin-like protein 1 involved_in ISO PMID:12772192 UniProt PMID:12772192 RGD:8553456 NCBI chr 4:49,153,654...49,270,384
Ensembl chr 4:54,987,767...55,104,461
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in ISO (PMID:26482878) BHF-UCL PMID:26482878 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:16043710), (PMID:17237768)
(PMID:15181449)
BHF-UCL PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PRKCQ protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G PTGES3 prostaglandin E synthase 3 involved_in ISO (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)
(PMID:19740745)
BHF-UCL PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr12:32,221,908...32,247,228
Ensembl chr12:32,476,835...32,503,181
JBrowse link
G TCP1 t-complex 1 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985
JBrowse link
G TNKS tankyrase involved_in ISO (PMID:12782650) BHF-UCL PMID:12782650 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:23685356), (PMID:25467444)
(MGI:6189679|PMID:29804836)
(PMID:19179534), (PMID:23685356), (PMID:29804836)
BHF-UCL
UniProt
PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 MGI:6189679 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in ISO PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 7:26,835,881...26,846,578
Ensembl chr 7:26,439,443...26,449,985
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) BHF-UCL PMID:22633954 MGI:5438900 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
positive regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) BHF-UCL PMID:22633954 MGI:5438900 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G NABP2 nucleic acid binding protein 2 involved_in ISO (PMID:25589350)
(MGI:5629774|PMID:25589350)
BHF-UCL PMID:25589350 MGI:5629774 NCBI chr12:32,685,521...32,693,318
Ensembl chr12:32,937,017...32,944,754
JBrowse link
G NEK2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G PRKCQ protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) BHF-UCL PMID:23959892
G TNKS tankyrase involved_in ISO (PMID:25939383)
(PMID:21531765)
BHF-UCL PMID:21531765 PMID:25939383 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G TNKS2 tankyrase 2 involved_in ISO (PMID:21531765)
(PMID:25939383)
BHF-UCL PMID:21531765 PMID:25939383 NCBI chr10:88,547,396...88,612,973
Ensembl chr10:92,070,362...92,134,911
JBrowse link
positive regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:4454526|PMID:20110566) UniProt PMID:20110566 MGI:4454526 NCBI chr  X:66,682,968...66,969,421
Ensembl chr  X:76,795,574...77,083,486
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:22238380) UniProt PMID:22238380 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G GNL3 G protein nucleolar 3 involved_in ISO (PMID:22641345) BHF-UCL PMID:22641345 NCBI chr 3:52,626,424...52,635,009
Ensembl chr 3:53,854,257...53,862,818
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966
JBrowse link
G NBN nibrin involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:22641345), (PMID:26119943) BHF-UCL PMID:22641345 PMID:26119943 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 involved_in ISO (PMID:23426265) BHF-UCL PMID:23426265 NCBI chr 6:30,342,669...30,359,644
Ensembl chr 6:31,212,522...31,229,697
JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr 5:127,972,630...128,059,911 JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
G SIRT6 sirtuin 6 involved_in ISO (PMID:23201774), (PMID:25819580) BHF-UCL PMID:23201774 PMID:25819580 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G TERF2 telomeric repeat binding factor 2 acts_upstream_of_or_within ISO (MGI:3615734|PMID:15968270) MGI PMID:15968270 MGI:3615734 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr 3:139,482,606...139,612,274
Ensembl chr 3:147,075,185...147,196,261
JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 1:131,652,058...131,679,802
Ensembl chr 1:135,481,427...135,508,983
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 5:10,565,911...10,580,808
Ensembl chr 5:10,424,157...10,440,613
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:56,664,757...56,677,000
Ensembl chr 7:57,087,072...57,098,613
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:73,287,026...73,305,792
Ensembl chr2A:74,775,781...74,794,515
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr21:15,489,698...15,507,292
Ensembl chr21:28,878,113...28,895,912
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO (MGI:3047190|PMID:15240872) MGI PMID:15240872 MGI:3047190 NCBI chr  X:144,243,493...144,257,419
Ensembl chr  X:154,084,412...154,098,475
JBrowse link
G FBXO4 F-box protein 4 involved_in ISO (PMID:16275645) BHF-UCL PMID:16275645 NCBI chr 5:68,336,673...68,474,481
Ensembl chr 5:73,500,850...73,517,051
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G NEK2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:17237768)
(PMID:12768206), (PMID:12781132)
BHF-UCL PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PRKCQ protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G TCP1 t-complex 1 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985
JBrowse link
G TNKS tankyrase involved_in ISO (PMID:12782650), (PMID:18221737)
(PMID:11739745)
BHF-UCL PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr2B:103,371,459...103,468,419
Ensembl chr2B:221,972,742...222,071,235
JBrowse link
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in ISO (PMID:17694070), (PMID:26586427) BHF-UCL PMID:17694070 PMID:26586427 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:21149580) UniProt PMID:21149580 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in ISO PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 7:26,835,881...26,846,578
Ensembl chr 7:26,439,443...26,449,985
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO (PMID:27510903) BHF-UCL PMID:27510903 NCBI chr 4:155,383,245...155,425,479
Ensembl chr 4:167,157,770...167,214,065
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) BHF-UCL PMID:23959892
positive regulation of telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
protection of DNA demethylation of female pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr12:7,834,298...7,841,064 JBrowse link
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 acts_upstream_of_or_within ISO (MGI:3577148|PMID:15703386) MGI PMID:15703386 MGI:3577148 NCBI chr  X:119,256,425...119,292,612
Ensembl chr  X:129,550,287...129,586,271
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO (MGI:3577148|PMID:15703386) MGI PMID:15703386 MGI:3577148 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) BHF-UCL PMID:12082630 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (MGI:1203887|PMID:9564035) BHF-UCL PMID:9564035 MGI:1203887 NCBI chr18:2,051,880...2,075,909 JBrowse link
regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:3617096|PMID:11981756) MGI PMID:11981756 MGI:3617096 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G PDGFA platelet derived growth factor subunit A NOT|involved_in ISO (PMID:11788434), (PMID:19019919) UniProt PMID:11788434 PMID:19019919 NCBI chr 7:648,722...672,023 JBrowse link
G SH2B1 SH2B adaptor protein 1 involved_in ISO (MGI:5009204|PMID:10644978) UniProt PMID:10644978 MGI:5009204 Ensembl chr16:29,249,597...29,263,334 JBrowse link
G TFDP1 transcription factor Dp-1 acts_upstream_of_or_within ISO (MGI:3525422|PMID:15448153) MGI PMID:15448153 MGI:3525422 NCBI chr13:94,730,343...94,789,328
Ensembl chr13:113,789,280...113,840,825
JBrowse link
G TOM1L1 target of myb1 like 1 membrane trafficking protein NOT|involved_in ISO (PMID:16479011) UniProt PMID:16479011 NCBI chr17:48,990,121...49,050,703
Ensembl chr17:53,855,447...53,916,592
JBrowse link
regulation of DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HELB DNA helicase B involved_in ISO (PMID:26774285)
(MGI:5766842|PMID:26774285)
UniProt PMID:26774285 MGI:5766842 NCBI chr12:22,571,448...22,607,417
Ensembl chr12:23,078,732...23,114,134
JBrowse link
regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA1 BRCA1 DNA repair associated involved_in ISO (MGI:5009779|PMID:20820192) BHF-UCL PMID:20820192 MGI:5009779 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in ISO (PMID:23254293)
(PMID:20938050)
UniProt PMID:20938050 PMID:23254293 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G KDM1B lysine demethylase 1B involved_in ISO (MGI:4358629|PMID:19727073) UniProt PMID:19727073 MGI:4358629 NCBI chr 6:18,002,763...18,071,598
Ensembl chr 6:18,355,907...18,425,552
JBrowse link
G LOC100993446 histone H1.8 involved_in ISO (MGI:5559660|PMID:22868987) UniProt PMID:22868987 MGI:5559660 NCBI chr 3:126,600,616...126,609,319
Ensembl chr 3:133,952,981...133,961,243
JBrowse link
G MBD1 methyl-CpG binding domain protein 1 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:43,647,395...43,662,266
Ensembl chr18:46,996,905...47,009,831
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:47,534,356...47,609,481 JBrowse link
G MBD3 methyl-CpG binding domain protein 3 ISO RGD PMID:20735989 RGD:9588647 Ensembl chr19:1,549,184...1,559,254 JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MIS18A MIS18 kinetochore protein A acts_upstream_of_or_within ISO (MGI:5438906|PMID:22516971) MGI PMID:22516971 MGI:5438906 NCBI chr21:18,635,735...18,646,611
Ensembl chr21:32,016,547...32,027,430
JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 involved_in ISO (PMID:20871592) UniProt PMID:20871592 NCBI chr13:932,620...999,853
Ensembl chr13:19,278,149...19,316,389
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23260200 RGD:10413908 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PRDM14 PR/SET domain 14 acts_upstream_of_or_within ISO (MGI:5506832|PMID:23670199) MGI PMID:23670199 MGI:5506832 NCBI chr 8:66,578,674...66,599,360
Ensembl chr 8:68,240,741...68,260,263
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:22041901 RGD:9491827 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G RLF RLF zinc finger acts_upstream_of_or_within ISO (MGI:5693990|PMID:25857663) MGI PMID:25857663 MGI:5693990 NCBI chr 1:39,448,869...39,528,061
Ensembl chr 1:40,773,638...40,852,218
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO (MGI:4939073|PMID:21295276) MGI PMID:21295276 MGI:4939073 NCBI chr10:65,036,313...65,168,051
Ensembl chr10:67,586,586...67,703,160
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5607719|PMID:20961378) MGI PMID:20961378 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
G ZNF595 zinc finger protein 595 acts_upstream_of_or_within ISO (MGI:5442238|PMID:22801370) MGI PMID:22801370 MGI:5442238 NCBI chr 4:50,243...92,219 JBrowse link
regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALYREF Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr17:76,293,410...76,297,171 JBrowse link
G SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 involved_in ISO (PMID:11031099) UniProt PMID:11031099 NCBI chr 4:86,567,722...86,651,527
Ensembl chr 4:97,240,614...97,324,366
JBrowse link
G THOC1 THO complex 1 involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr18:14,052,858...14,102,559
Ensembl chr18:17,692,797...17,742,570
JBrowse link
regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK9 cyclin dependent kinase 9 involved_in ISO (PMID:20493174) UniProt PMID:20493174 NCBI chr 9:98,905,468...98,909,923
Ensembl chr 9:127,580,862...127,584,935
JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:5432078|PMID:20467439) MGI PMID:20467439 MGI:5432078 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G SIRT7 sirtuin 7 involved_in ISO (PMID:27436229), (PMID:30944854) UniProt PMID:27436229 PMID:30944854 NCBI chr17:76,317,560...76,323,761
Ensembl chr17:82,020,077...82,026,289
JBrowse link
G SUV39H1 suppressor of variegation 3-9 homolog 1 acts_upstream_of_or_within ISO (MGI:5913114|PMID:23695662) MGI PMID:23695662 MGI:5913114 NCBI chr  X:40,993,911...41,007,362
Ensembl chr  X:48,855,494...48,868,131
JBrowse link
G USP1 ubiquitin specific peptidase 1 involved_in ISO (PMID:18082604) UniProt PMID:18082604 NCBI chr 1:61,694,775...61,710,216
Ensembl chr 1:63,510,196...63,525,446
JBrowse link
regulation of DNA strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chr 1:181,322,760...181,359,321
Ensembl chr 1:185,606,796...185,642,984
JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in ISO (PMID:23966166) UniProt PMID:23966166 NCBI chr10:58,894,939...58,923,176
Ensembl chr10:61,223,925...61,329,657
JBrowse link
regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146)
(MGI:2388867|PMID:12192004)
UniProt PMID:11125146 PMID:12192004 MGI:2388867 NCBI chr16:69,516,728...69,522,419
Ensembl chr16:89,174,071...89,177,823
JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chr17:43,875,921...43,916,352
Ensembl chr17:48,605,488...48,645,784
JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in ISO (PMID:20116089) UniProt PMID:20116089 NCBI chr15:68,270,029...68,322,201
Ensembl chr15:87,476,738...87,528,870
JBrowse link
G WRNIP1 WRN helicase interacting protein 1 involved_in ISO (PMID:15670210) UniProt PMID:15670210 NCBI chr 6:2,587,170...2,608,179
Ensembl chr 6:2,691,235...2,711,062
JBrowse link
regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEK DEK proto-oncogene acts_upstream_of_or_within ISO (PMID:21653549) MGI PMID:21653549 NCBI chr 6:18,071,928...18,112,245
Ensembl chr 6:18,427,844...18,465,606
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:21639834) UniProt PMID:21639834 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 involved_in ISO (PMID:15665856) UniProt PMID:15665856 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981
JBrowse link
G FIGNL1 fidgetin like 1 involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chr 7:51,080,052...51,093,694 JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within ISO (PMID:24217620) MGI PMID:24217620 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692
JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit involved_in ISO (PMID:20154705) UniProt PMID:20154705 Ensembl chr16:30,450,467...30,464,446 JBrowse link
G PPP4R2 protein phosphatase 4 regulatory subunit 2 involved_in ISO (PMID:20154705) UniProt PMID:20154705 NCBI chr 3:72,939,529...73,012,073
Ensembl chr 3:74,835,788...74,935,446
JBrowse link
G RAD51 RAD51 recombinase involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chr15:19,638,310...19,672,474
Ensembl chr15:37,891,056...37,925,207
JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chr12:4,657,972...4,679,232
Ensembl chr12:4,578,621...4,599,879
JBrowse link
G RPA2 replication protein A2 involved_in ISO (PMID:20154705) UniProt PMID:20154705 NCBI chr 1:27,151,784...27,175,110
Ensembl chr 1:28,191,731...28,214,666
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:18957201) UniProt PMID:18957201
G SETD2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:24843002) UniProt PMID:24843002 NCBI chr 3:46,916,615...47,064,046
Ensembl chr 3:48,018,517...48,163,999
JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (PMID:19135889) UniProt PMID:19135889 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chr 8:43,691,454...44,166,259
Ensembl chr 8:41,083,964...41,558,170
JBrowse link
G TERF2IP TERF2 interacting protein involved_in ISO (MGI:4440768|PMID:20339076) UniProt PMID:20339076 MGI:4440768 NCBI chr16:56,216,920...56,226,612
Ensembl chr16:75,565,184...75,573,882
JBrowse link
G TEX15 testis expressed 15, meiosis and synapsis associated acts_upstream_of_or_within ISO (MGI:3794139|PMID:18283110) MGI PMID:18283110 MGI:3794139 NCBI chr 8:30,145,628...30,232,903
Ensembl chr 8:27,334,129...27,420,049
JBrowse link
G USP51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) UniProt PMID:27083998 NCBI chr  X:47,747,547...47,753,119 JBrowse link
G ZNF365 zinc finger protein 365 involved_in ISO (PMID:23966166) UniProt PMID:23966166 NCBI chr10:58,894,939...58,923,176
Ensembl chr10:61,223,925...61,329,657
JBrowse link
regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 NOT|involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G DEK DEK proto-oncogene acts_upstream_of_or_within ISO (MGI:5317387|PMID:21653549) MGI PMID:21653549 MGI:5317387 NCBI chr 6:18,071,928...18,112,245
Ensembl chr 6:18,427,844...18,465,606
JBrowse link
G MRNIP MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chr 5:174,989,967...175,020,550
Ensembl chr 5:182,299,016...182,340,632
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) MGI PMID:23241889 MGI:5462481 NCBI chr 4:2,009,276...2,119,182
Ensembl chr 4:1,945,307...2,027,425
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:29227966) CACAO PMID:29227966 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G SIRT7 sirtuin 7 involved_in ISO (MGI:5789069|PMID:27225932) UniProt PMID:27225932 MGI:5789069 NCBI chr17:76,317,560...76,323,761
Ensembl chr17:82,020,077...82,026,289
JBrowse link
G USP51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) UniProt PMID:27083998 NCBI chr  X:47,747,547...47,753,119 JBrowse link
G WAS WASP actin nucleation promoting factor NOT|involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380
JBrowse link
regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 involved_in ISO (PMID:19188445) UniProt PMID:19188445 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:19934257) UniProt PMID:19934257 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor acts_upstream_of_or_within ISO (MGI:4887518|PMID:21211721) MGI PMID:21211721 MGI:4887518 NCBI chr2A:68,509,314...68,629,192
Ensembl chr2A:69,632,459...69,744,611
JBrowse link
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) UniProt PMID:21518874 MGI:5004983 NCBI chr17:28,073,288...28,113,041
Ensembl chr17:28,578,199...28,617,292
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:3695768|PMID:16275384) MGI PMID:16275384 MGI:3695768 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (MGI:1926579|PMID:11057672) MGI PMID:11057672 MGI:1926579 Ensembl chr19:14,323,618...14,343,627 JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chr 5:137,467,161...137,511,569
Ensembl chr 5:143,600,789...143,622,913
JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chr12:126,418,071...126,448,917 JBrowse link
regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN2 axin 2 involved_in ISO (PMID:11017067) BHF-UCL PMID:11017067 NCBI chr17:59,476,336...59,509,358
Ensembl chr17:64,688,416...64,720,086
JBrowse link
regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPV17 mitochondrial inner membrane protein MPV17 involved_in ISO (PMID:26760297)
(MGI:5776643|PMID:26760297)
UniProt PMID:26760297 MGI:5776643 NCBI chr2A:27,311,551...27,325,249
Ensembl chr2A:27,399,258...27,414,090
JBrowse link
G STOX1 storkhead box 1 involved_in ISO (PMID:24738702) UniProt PMID:24738702 NCBI chr10:65,304,649...65,359,501
Ensembl chr10:67,882,654...67,894,039
JBrowse link
regulation of mitotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAD50 RAD50 double strand break repair protein involved_in ISO (PMID:8756642) UniProt PMID:8756642 NCBI chr 5:127,972,630...128,059,911 JBrowse link
regulation of nucleotide-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUL4A cullin 4A acts_upstream_of_or_within ISO (MGI:3850765|PMID:19481525) MGI PMID:19481525 MGI:3850765 NCBI chr13:94,350,484...94,409,183
Ensembl chr13:113,428,271...113,472,701
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (MGI:3807115|PMID:18650382) UniProt PMID:18650382 MGI:3807115 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in ISO (PMID:28719581) UniProt PMID:28719581 NCBI chr17:43,875,921...43,916,352
Ensembl chr17:48,605,488...48,645,784
JBrowse link
G RAD52 RAD52 homolog, DNA repair protein acts_upstream_of_or_within ISO (PMID:19506022) MGI PMID:19506022 NCBI chr12:986,372...1,066,708
Ensembl chr12:946,825...985,668
JBrowse link
regulation of restriction endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:17803946) UniProt PMID:17803946 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (MGI:5616996|PMID:25378300) MGI PMID:25378300 MGI:5616996 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase NOT|involved_in ISO (PMID:26586427) BHF-UCL PMID:26586427 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G NABP2 nucleic acid binding protein 2 NOT|involved_in ISO (PMID:25589350) BHF-UCL PMID:25589350 NCBI chr12:32,685,521...32,693,318
Ensembl chr12:32,937,017...32,944,754
JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 involved_in ISO (PMID:15169895) BHF-UCL PMID:15169895 NCBI chr13:5,734,322...5,827,323
Ensembl chr13:24,029,405...24,113,075
JBrowse link
regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC8 histone deacetylase 8 involved_in ISO (PMID:16809764) BHF-UCL PMID:16809764 NCBI chr  X:61,565,790...61,811,588 JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) BHF-UCL PMID:22633954 MGI:5438900 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
G LMNA lamin A/C involved_in ISO (PMID:25399868) BHF-UCL PMID:25399868 NCBI chr 1:131,456,819...131,482,275
Ensembl chr 1:135,253,700...135,311,539
JBrowse link
G LOC103783967 SMG1 nonsense mediated mRNA decay associated PI3K related kinase involved_in ISO (PMID:17916692) BHF-UCL PMID:17916692 NCBI chr16:19,433,999...19,475,539 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:17765874) BHF-UCL PMID:17765874 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649) HGNC-UCL PMID:16522649 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311
JBrowse link
G SMG5 SMG5 nonsense mediated mRNA decay factor involved_in ISO (PMID:16809764) BHF-UCL PMID:16809764 NCBI chr 1:131,592,368...131,634,443
Ensembl chr 1:135,422,268...135,455,734
JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12699629), (PMID:17916692) BHF-UCL PMID:12699629 PMID:17916692 NCBI chr17:2,050,825...2,294,892
Ensembl chr17:1,937,630...2,179,535
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:22536324) CACAO PMID:22536324 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G UPF1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:17916692) BHF-UCL PMID:17916692 NCBI chr19:18,269,878...18,306,199
Ensembl chr19:19,292,725...19,313,224
JBrowse link
G YLPM1 YLP motif containing 1 acts_upstream_of_or_within ISO (MGI:3525956|PMID:15100092) MGI PMID:15100092 MGI:3525956 NCBI chr14:55,315,429...55,388,330
Ensembl chr14:74,160,867...74,232,769
JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:19864690)
(PMID:23685356)
BHF-UCL PMID:19864690 PMID:23685356 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TINF2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:18669893) BHF-UCL PMID:18669893 NCBI chr14:5,015,862...5,019,228
Ensembl chr14:23,139,445...23,142,825
JBrowse link
regulation of transcription-coupled nucleotide-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:16916636), (PMID:17297471) UniProt PMID:16916636 PMID:17297471 NCBI chr 5:53,053,712...53,131,563
Ensembl chr 5:54,693,987...54,765,496
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12654
    metabolic process 7926
      regulation of metabolic process 5178
        regulation of macromolecule metabolic process 4754
          regulation of DNA metabolic process 362
            negative regulation of DNA metabolic process + 114
            positive regulation of DNA metabolic process + 218
            regulation of DNA biosynthetic process + 122
            regulation of DNA catabolic process + 14
            regulation of DNA demethylation + 8
            regulation of DNA double-strand break processing 1
            regulation of DNA ligation + 5
            regulation of DNA methylation + 30
            regulation of DNA recombination + 94
            regulation of DNA repair + 124
            regulation of DNA replication termination + 0
            regulation of DNA strand elongation + 2
            regulation of DNA strand resection involved in replication fork processing + 1
            regulation of DNA-dependent DNA replication initiation + 6
            regulation of deoxyribonuclease activity + 10
            regulation of mitochondrial DNA metabolic process + 4
            regulation of replication fork arrest at rDNA repeats 0
            regulation of strand invasion + 1
            regulation of telomere maintenance + 79
            regulation of transposon integration + 1
Path 2
Term Annotations click to browse term
  biological_process 12654
    cellular process 11787
      cellular metabolic process 7262
        heterocycle metabolic process 3838
          nucleobase-containing compound metabolic process 3734
            nucleic acid metabolic process 3420
              DNA metabolic process 682
                regulation of DNA metabolic process 362
                  negative regulation of DNA metabolic process + 114
                  positive regulation of DNA metabolic process