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ONTOLOGY REPORT - ANNOTATIONS


Term:barbed-end actin filament capping
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Accession:GO:0051016 term browser browse the term
Definition:The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:exact_synonym: barbed-end F-actin capping activity;   barbed-end actin capping activity;   plus-end F-actin capping activity;   plus-end actin filament capping activity


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barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004936477:20,695,109...20,766,053 JBrowse link
G Add2 adducin 2 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004936491:14,856,764...14,971,161 JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chrNW_004936690:1,184,644...1,223,732 JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chrNW_004936474:5,594,193...5,656,665 JBrowse link
G Dbnl drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chrNW_004936478:19,007,630...19,021,068 JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in ISO (MGI:5476881|PMID:23314863)
(MGI:4460022|PMID:20532239), (MGI:5486559|PMID:15558031)
UniProt PMID:15558031 PMID:20532239 PMID:23314863 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chrNW_004936587:1,785,721...1,951,474 JBrowse link
G Rdx radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chrNW_004936612:3,992,542...4,060,598 JBrowse link
G Twf1 twinfilin actin binding protein 1 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chrNW_004936512:2,280,266...2,293,101 JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chrNW_004936569:914,511...938,481 JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chrNW_004936671:1,404,595...1,632,916 JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chrNW_004936475:18,036,233...18,049,144 JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chrNW_004936482:18,309,078...18,557,335 JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004936569:758,358...786,995 JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chrNW_004936599:3,678,724...3,682,314 JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO (PMID:16895918) UniProt PMID:16895918 NCBI chrNW_004936592:644,618...679,615 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12135
    cellular process 11327
      negative regulation of cellular process 4267
        negative regulation of cellular component organization 699
          negative regulation of supramolecular fiber organization 138
            negative regulation of actin filament depolymerization 25
              actin filament capping 19
                barbed-end actin filament capping 15
                  negative regulation of barbed-end actin filament capping 3
                  positive regulation of barbed-end actin filament capping 2
                  regulation of barbed-end actin filament capping + 6
Path 2
Term Annotations click to browse term
  biological_process 12135
    cellular process 11327
      cellular component organization or biogenesis 5022
        cellular component organization 4941
          organelle organization 3067
            cytoskeleton organization 1100
              actin cytoskeleton organization 554
                actin filament organization 339
                  actin polymerization or depolymerization 164
                    regulation of actin polymerization or depolymerization 138
                      regulation of actin filament depolymerization 34
                        negative regulation of actin filament depolymerization 25
                          actin filament capping 19
                            barbed-end actin filament capping 15
                              negative regulation of barbed-end actin filament capping 3
                              positive regulation of barbed-end actin filament capping 2
                              regulation of barbed-end actin filament capping + 6
paths to the root