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ONTOLOGY REPORT - ANNOTATIONS


Term:barbed-end actin filament capping
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Accession:GO:0051016 term browser browse the term
Definition:The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:exact_synonym: barbed-end F-actin capping activity;   barbed-end actin capping activity;   plus-end F-actin capping activity;   plus-end actin filament capping activity


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barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik RIKEN cDNA 4933400A11 gene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:25,737,292...25,738,155 JBrowse link
G Add1 adducin 1 involved_in ISO
IBA
(PMID:8626479)
PMID:21873635
RGD PMID:8626479, PMID:21873635 RGD:13792537 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Add2 adducin 2 involved_in ISO
IBA
IEA
(PMID:8626479)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8626479, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
JBrowse link
G Add3 adducin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Avil advillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3758397|PMID:17656356)
RGD PMID:17656356, PMID:21873635 MGI:3758397, RGD:13792537 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 4:174,181,644...174,182,857
Ensembl chr 4:174,181,644...174,182,856
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000104
(MGI:3758397|PMID:17656356)
PMID:21873635
UniProt
RGD
PMID:17656356, PMID:21873635 GO_REF:0000104 MGI:3758397, RGD:13792537 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Dbnl drebrin-like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) RGD PMID:10637315 MGI:1353214 NCBI chr14:86,029,335...86,044,364
Ensembl chr14:86,029,335...86,044,364
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4460022|PMID:20532239), (MGI:5476881|PMID:23314863), (MGI:5486559|PMID:15558031)
UniProt
RGD
PMID:15558031 PMID:20532239 PMID:23314863 GO_REF:0000024 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:46,955,460...46,969,468
Ensembl chr10:46,955,487...46,969,406
JBrowse link
G Gsn gelsolin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Rdx radixin IDA RGD PMID:2500445 RGD:8693627 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G RGD1563947 similar to RIKEN cDNA 4933400A11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:25,737,281...25,738,144 JBrowse link
G Scin scinderin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:59,975,375...60,055,075
Ensembl chr 6:59,976,003...60,054,279
JBrowse link
G Svil supervillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279
JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697, PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542
JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697, PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 8:114,897,011...114,909,531
Ensembl chr 8:114,897,011...114,909,531
JBrowse link
G Vil1 villin 1 involved_in ISO
IBA
(PMID:15272027)
PMID:21873635
RGD PMID:15272027, PMID:21873635 RGD:13792537 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
G Vill villin-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:127,735,233...127,753,313
Ensembl chr 8:127,735,258...127,753,349
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
PMID:21873635
RGD PMID:30361697, PMID:21873635 RGD:13792537 NCBI chr14:33,649,989...33,783,794
Ensembl chr14:33,649,637...33,677,031
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:148,139,512...148,197,363
Ensembl chr 4:148,139,528...148,197,365
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:23704350 RGD:11570555 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO
ISS
IBA
(PMID:16895918)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:16895918, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      negative regulation of cellular process 5102
        negative regulation of cellular component organization 796
          negative regulation of supramolecular fiber organization 181
            negative regulation of actin filament depolymerization 51
              actin filament capping 45
                barbed-end actin filament capping 29
                  negative regulation of barbed-end actin filament capping 4
                  positive regulation of barbed-end actin filament capping 2
                  regulation of barbed-end actin filament capping + 7
Path 2
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      cellular component organization or biogenesis 6724
        cellular component organization 6479
          organelle organization 4057
            cytoskeleton organization 1447
              actin cytoskeleton organization 744
                actin filament organization 466
                  actin polymerization or depolymerization 232
                    regulation of actin polymerization or depolymerization 200
                      regulation of actin filament depolymerization 61
                        negative regulation of actin filament depolymerization 51
                          actin filament capping 45
                            barbed-end actin filament capping 29
                              negative regulation of barbed-end actin filament capping 4
                              positive regulation of barbed-end actin filament capping 2
                              regulation of barbed-end actin filament capping + 7
paths to the root