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ONTOLOGY REPORT - ANNOTATIONS


Term:barbed-end actin filament capping
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Accession:GO:0051016 term browser browse the term
Definition:The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:exact_synonym: barbed-end F-actin capping activity;   barbed-end actin capping activity;   plus-end F-actin capping activity;   plus-end actin filament capping activity


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barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC097637.1 novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr 3:52,221,081...52,231,190 JBrowse link
G ADD1 adducin 1 involved_in IDA
IBA
(PMID:8626479)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:8626479 PMID:21873635 NCBI chr 4:2,843,844...2,930,065
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G ADD2 adducin 2 involved_in IDA
IBA
(PMID:8626479)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:8626479 PMID:21873635 NCBI chr 2:70,656,784...70,768,200
Ensembl chr 2:70,607,618...70,768,225
JBrowse link
G ADD3 adducin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:109,996,365...110,135,565
Ensembl chr10:109,996,368...110,135,565
JBrowse link
G AVIL advillin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:57,797,376...57,818,734
Ensembl chr12:57,797,376...57,818,704
JBrowse link
G CAPG capping actin protein, gelsolin like involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr 2:85,394,753...85,418,467
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3758397|PMID:17656356)
GO_Central
MGI
PMID:17656356 PMID:21873635 MGI:3758397 NCBI chr 1:112,619,775...112,671,616
Ensembl chr 1:112,619,805...112,671,616
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr 7:116,862,587...116,922,049
Ensembl chr 7:116,811,070...116,922,049
JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:18,738,119...18,739,188
Ensembl chr12:18,738,119...18,739,188
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:3758397|PMID:17656356)
(PMID:21873635)
UniProt
MGI
GO_Central
PMID:17656356 PMID:21873635 GO_REF:0000104 MGI:3758397 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chr 7:44,044,702...44,069,456
Ensembl chr 7:44,044,640...44,069,456
JBrowse link
G EPS8 epidermal growth factor receptor pathway substrate 8 involved_in IEA
ISS
InterPro
UniProt
GO_REF:0000002 GO_REF:0000024 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
JBrowse link
G FLII FLII actin remodeling protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:18,244,815...18,259,022
Ensembl chr17:18,244,815...18,258,738
JBrowse link
G GSN gelsolin involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
InterPro
PMID:21873635 GO_REF:0000002 GO_REF:0000104 NCBI chr 9:121,201,483...121,332,844
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:136,862,208...136,951,606
Ensembl chr 3:136,862,208...136,951,606
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:105,744,649...105,894,274
Ensembl chr 2:105,744,912...105,894,274
JBrowse link
G RDX radixin involved_in IEA
ISO
Ensembl
RGD
PMID:2500445 GO_REF:0000107 RGD:8693627 NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712
JBrowse link
G SCIN scinderin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:12,570,720...12,660,182
Ensembl chr 7:12,570,577...12,660,182
JBrowse link
G SVIL supervillin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:29,457,338...29,736,936
Ensembl chr10:29,457,338...29,736,959
JBrowse link
G TRIOBP TRIO and F-actin binding protein involved_in NAS (PMID:11148140) UniProt PMID:11148140 NCBI chr22:37,697,048...37,776,556
Ensembl chr22:37,697,048...37,776,556
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in ISS
IBA
(PMID:18837697)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:18837697 PMID:21873635 NCBI chr 3:52,228,612...52,239,158
Ensembl chr 3:52,228,612...52,246,788
JBrowse link
G VIL1 villin 1 involved_in IBA
IMP
(PMID:21873635)
(PMID:15272027)
GO_Central
UniProt
PMID:15272027 PMID:21873635 NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
JBrowse link
G VILL villin like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA
ISS
InterPro
UniProt
GO_REF:0000002 GO_REF:0000024 NCBI chr 6:25,279,374...25,620,530
Ensembl chr 6:25,279,078...25,620,530
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IDA (PMID:26466680) UniProt PMID:26466680 NCBI chr16:67,645,004...67,657,569
Ensembl chr16:67,644,988...67,657,569
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IBA
IDA
(PMID:21873635)
(PMID:30361697)
GO_Central
UniProt
PMID:21873635 PMID:30361697 NCBI chr 4:56,049,098...56,330,622
Ensembl chr 4:56,049,098...56,330,609
JBrowse link
G WASHC2C WASH complex subunit 2C involved_in IDA (PMID:20498093) UniProt PMID:20498093 NCBI chr10:45,727,043...45,792,964
Ensembl chr10:45,727,200...45,792,964
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr 2:218,217,138...218,254,348
Ensembl chr 2:218,217,141...218,254,356
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IQANK1 IQ motif and ankyrin repeat containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:143,734,139...143,790,702
Ensembl chr 8:143,734,139...143,790,645
JBrowse link
G MTPN myotrophin involved_in IBA
IDA
(PMID:21873635)
(PMID:16895918)
GO_Central
UniProt
PMID:16895918 PMID:21873635 NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18666
    cellular process 17731
      negative regulation of cellular process 5520
        negative regulation of cellular component organization 842
          negative regulation of supramolecular fiber organization 185
            negative regulation of actin filament depolymerization 55
              actin filament capping 49
                barbed-end actin filament capping 32
                  negative regulation of barbed-end actin filament capping 4
                  positive regulation of barbed-end actin filament capping 2
                  regulation of barbed-end actin filament capping + 8
Path 2
Term Annotations click to browse term
  biological_process 18666
    cellular process 17731
      cellular component organization or biogenesis 7316
        cellular component organization 7100
          organelle organization 4408
            cytoskeleton organization 1587
              actin cytoskeleton organization 770
                actin filament organization 477
                  actin polymerization or depolymerization 241
                    regulation of actin polymerization or depolymerization 209
                      regulation of actin filament depolymerization 64
                        negative regulation of actin filament depolymerization 55
                          actin filament capping 49
                            barbed-end actin filament capping 32
                              negative regulation of barbed-end actin filament capping 4
                              positive regulation of barbed-end actin filament capping 2
                              regulation of barbed-end actin filament capping + 8
paths to the root