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ONTOLOGY REPORT - ANNOTATIONS


Term:barbed-end actin filament capping
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Accession:GO:0051016 term browser browse the term
Definition:The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:exact_synonym: barbed-end F-actin capping activity;   barbed-end actin capping activity;   plus-end F-actin capping activity;   plus-end actin filament capping activity


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barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955514:1,784,302...1,812,845
Ensembl chrNW_004955514:1,783,814...1,815,917
JBrowse link
G Add2 adducin 2 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955424:14,411,279...14,517,813
Ensembl chrNW_004955424:14,411,124...14,517,813
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chrNW_004955435:16,048,213...16,087,814
Ensembl chrNW_004955435:16,048,213...16,087,814
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chrNW_004955452:34,454...168,514
Ensembl chrNW_004955452:30,589...169,693
JBrowse link
G Dbnl drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chrNW_004955456:7,912,827...7,924,373
Ensembl chrNW_004955456:7,912,827...7,924,787
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in ISO (MGI:4460022|PMID:20532239), (MGI:5486559|PMID:15558031)
(MGI:5476881|PMID:23314863)
UniProt PMID:15558031 PMID:20532239 PMID:23314863 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chrNW_004955413:12,267,701...12,386,088
Ensembl chrNW_004955413:12,266,371...12,386,088
JBrowse link
G Rdx radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chrNW_004955412:12,100,436...12,184,444
Ensembl chrNW_004955412:12,100,359...12,172,545
JBrowse link
G Twf1 twinfilin actin binding protein 1 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chrNW_004955500:3,050,028...3,070,799 JBrowse link
G Twf2 twinfilin actin binding protein 2 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chrNW_004955484:9,025,409...9,037,942
Ensembl chrNW_004955484:9,025,460...9,037,580
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chrNW_004955447:14,650,035...14,672,593 JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chrNW_004955546:2,718,758...2,764,277 JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041
JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO (PMID:16895918) UniProt PMID:16895918 NCBI chrNW_004955494:6,805,518...6,844,454
Ensembl chrNW_004955494:6,805,262...6,845,394
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11938
    cellular process 11169
      negative regulation of cellular process 4215
        negative regulation of cellular component organization 689
          negative regulation of supramolecular fiber organization 137
            negative regulation of actin filament depolymerization 27
              actin filament capping 21
                barbed-end actin filament capping 17
                  negative regulation of barbed-end actin filament capping 4
                  positive regulation of barbed-end actin filament capping 2
                  regulation of barbed-end actin filament capping + 7
Path 2
Term Annotations click to browse term
  biological_process 11938
    cellular process 11169
      cellular component organization or biogenesis 4950
        cellular component organization 4867
          organelle organization 3011
            cytoskeleton organization 1074
              actin cytoskeleton organization 537
                actin filament organization 327
                  actin polymerization or depolymerization 158
                    regulation of actin polymerization or depolymerization 133
                      regulation of actin filament depolymerization 36
                        negative regulation of actin filament depolymerization 27
                          actin filament capping 21
                            barbed-end actin filament capping 17
                              negative regulation of barbed-end actin filament capping 4
                              positive regulation of barbed-end actin filament capping 2
                              regulation of barbed-end actin filament capping + 7
paths to the root