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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament binding
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Accession:GO:0051015 term browser browse the term
Definition:Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
Synonyms:exact_synonym: F-actin binding
 related_synonym: actin cross-linking activity


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actin filament binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABITRAM actin binding transcription modulator JBrowse link 1 249,898,994 249,905,397 RGD:14298760
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:14298760
G ABLIM1 actin binding LIM protein 1 JBrowse link 14 124,759,811 125,108,722 RGD:14298760
G ABLIM2 actin binding LIM protein family member 2 JBrowse link 8 2,948,948 3,054,974 RGD:14298760
G ABLIM3 actin binding LIM protein family member 3 JBrowse link 2 150,260,185 150,423,214 RGD:14298760
G ACTN1 actinin alpha 1 JBrowse link 7 92,550,132 92,644,842 RGD:14298760
G ACTN2 actinin alpha 2 JBrowse link 14 54,670,727 54,742,717 RGD:9068941
G ACTN3 actinin alpha 3 JBrowse link 2 5,860,386 5,873,779 RGD:9068941
G ACTN4 actinin alpha 4 JBrowse link 6 47,493,834 47,565,999 RGD:14298760
G ACTR2 actin related protein 2 JBrowse link 3 76,691,275 76,729,269 RGD:14298760
G ACTR3 actin related protein 3 JBrowse link 15 20,104,808 20,171,721 RGD:14298760
G ACTR3B actin related protein 3B JBrowse link 18 4,637,408 4,748,233 RGD:14298760
G ADD1 adducin 1 JBrowse link 8 1,627,146 1,710,653 RGD:14298760
G ADD2 adducin 2 JBrowse link 3 71,729,882 71,845,761 RGD:14298760
G ADD3 adducin 3 JBrowse link 14 120,451,421 120,583,725 RGD:14298760
G ADSS1 adenylosuccinate synthase 1 RGD:9068941
G AFDN afadin, adherens junction formation factor JBrowse link 1 1,569,652 1,698,475 RGD:9068941
G AIF1 allograft inflammatory factor 1 JBrowse link 7 23,711,752 23,731,191 RGD:14298760
G AIF1L allograft inflammatory factor 1 like JBrowse link 1 271,075,376 271,099,984 RGD:14298760
G AJUBA ajuba LIM protein JBrowse link 7 76,063,009 76,072,884 RGD:14298760
G ANTXR1 ANTXR cell adhesion molecule 1 JBrowse link 3 73,157,744 73,398,379 RGD:9068941
G ANXA6 annexin A6 JBrowse link 16 71,857,229 71,913,723 RGD:14298760
G ANXA8 annexin A8 JBrowse link 14 88,319,209 88,340,716 RGD:9068941
G ARPC1A actin related protein 2/3 complex subunit 1A JBrowse link 3 6,296,257 6,324,526 RGD:14298760
G ARPC1B actin related protein 2/3 complex subunit 1B JBrowse link 3 6,329,737 6,342,641 RGD:14298760
RGD:9068941
G ARPC2 actin related protein 2/3 complex subunit 2 JBrowse link 15 120,297,122 120,328,795 RGD:14298760
RGD:9068941
G ARPC3 actin related protein 2/3 complex subunit 3 JBrowse link 14 31,814,382 31,823,452 RGD:14298760
G ARPC4 actin related protein 2/3 complex subunit 4 JBrowse link 13 66,075,926 66,093,986 RGD:14298760
RGD:9068941
G ARPC5 actin related protein 2/3 complex subunit 5 JBrowse link 9 124,839,062 124,847,906 RGD:14298760
RGD:9068941
G ARPP19 cAMP regulated phosphoprotein 19 JBrowse link 1 119,134,318 119,157,169 RGD:14298760
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 1 95,738,789 95,750,835 RGD:14298760
G AVIL advillin JBrowse link 5 23,087,946 23,110,602 RGD:14298760
G BIN1 bridging integrator 1 JBrowse link 15 25,328,679 25,379,675 RGD:14298760
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 JBrowse link 1 126,168,944 126,184,813 RGD:9068941
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 10 44,321,954 44,887,410 RGD:14298760
G CAMSAP3 calmodulin regulated spectrin associated protein family member 3 JBrowse link 2 71,531,607 71,547,413 RGD:14298760
G CAPG capping actin protein, gelsolin like JBrowse link 3 59,335,483 59,366,855 RGD:14298760
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 JBrowse link 4 107,769,570 107,821,806 RGD:9068941
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 JBrowse link 18 29,316,384 29,365,062 RGD:14298760
G CAPZB capping actin protein of muscle Z-line subunit beta JBrowse link 6 77,780,682 77,912,653 RGD:14298760
RGD:9068941
G CCIN calicin JBrowse link 1 236,947,871 236,950,447 RGD:14298760
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 JBrowse link 12 42,456,063 42,494,494 RGD:14298760
G CFL1 cofilin 1 JBrowse link 2 6,471,558 6,475,019 RGD:14298760
G CFL2 cofilin 2 JBrowse link 7 65,090,170 65,094,521 RGD:14298760
G CLASP2 cytoplasmic linker associated protein 2 JBrowse link 13 19,305,430 19,510,589 RGD:9068941
G CLMN calmin JBrowse link 7 116,476,789 116,590,181 RGD:14298760
G CNN2 calponin 2 JBrowse link 2 77,376,020 77,385,594 RGD:14298760
G CORO1A coronin 1A JBrowse link 3 18,336,813 18,342,381 RGD:14298760
G CORO1B coronin 1B JBrowse link 2 5,081,294 5,086,698 RGD:14298760
G CORO1C coronin 1C JBrowse link 14 42,062,468 42,145,130 RGD:14298760
G CORO2A coronin 2A JBrowse link 1 239,947,299 240,000,964 RGD:14298760
G CORO2B coronin 2B JBrowse link 1 166,465,870 166,608,840 RGD:14298760
G CORO6 coronin 6 JBrowse link 12 45,806,007 45,814,594 RGD:14298760
G CTNNA1 catenin alpha 1 JBrowse link 2 140,682,776 140,869,828 RGD:14298760
G CTNNA2 catenin alpha 2 JBrowse link 3 63,205,073 64,417,990 RGD:14298760
G CTNNA3 catenin alpha 3 JBrowse link 14 69,195,231 70,974,543 RGD:14298760
G CTNNAL1 catenin alpha like 1 JBrowse link 1 250,005,444 250,078,448 RGD:14298760
G CTTN cortactin JBrowse link 2 3,031,103 3,060,796 RGD:14298760
G DBN1 drebrin 1 JBrowse link 2 80,480,603 80,495,797 RGD:14298760
G DBNL drebrin like JBrowse link 18 48,713,335 48,725,692 RGD:14298760
G DMTN dematin actin binding protein JBrowse link 14 6,315,643 6,346,722 RGD:14298760
G DSTN destrin, actin depolymerizing factor JBrowse link 17 25,998,830 26,050,354 RGD:14298760
G EEF2 eukaryotic translation elongation factor 2 JBrowse link 2 74,746,541 74,756,687 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:14298760
G EPS8L3 EPS8 like 3 JBrowse link 4 110,311,533 110,326,999 RGD:9068941
G ERMN ermin JBrowse link 15 64,286,038 64,293,270 RGD:14298760
G ESPN espin JBrowse link 6 67,284,106 67,316,577 RGD:14298760
G ESPNL espin like JBrowse link 15 137,674,867 137,706,968 RGD:14298760
G EZR ezrin JBrowse link 1 8,403,362 8,452,750 RGD:14298760
G FERMT1 fermitin family member 1 JBrowse link 17 15,080,585 15,137,947 RGD:14298760
G FERMT2 fermitin family member 2 JBrowse link 1 182,519,681 182,606,890 RGD:9068941
G FGD4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 5 41,683,265 41,879,197 RGD:9068941
G FHOD3 formin homology 2 domain containing 3 JBrowse link 6 120,036,824 120,585,987 RGD:14298760
G FLII FLII actin remodeling protein JBrowse link 12 60,475,722 60,487,376 RGD:14298760
G FLNA filamin A JBrowse link X 124,889,934 124,915,000 RGD:14298760
G FMNL1 formin like 1 JBrowse link 12 18,198,764 18,225,621 RGD:14298760
G FMNL2 formin like 2 JBrowse link 15 60,054,300 60,384,666 RGD:14298760
G FMNL3 formin like 3 JBrowse link 5 15,592,665 15,646,059 RGD:14298760
G FRG1 FSHD region gene 1 JBrowse link 17 5,780,847 5,800,503 RGD:14298760
G FSCN1 fascin actin-bundling protein 1 JBrowse link 3 4,134,173 4,143,275 RGD:14298760
G FSCN2 fascin actin-bundling protein 2, retinal JBrowse link 12 1,300,286 1,311,562 RGD:14298760
G FSCN3 fascin actin-bundling protein 3 JBrowse link 18 20,684,621 20,693,552 RGD:14298760
G GAS2 growth arrest specific 2 JBrowse link 2 36,712,758 36,885,436 RGD:14298760
G GAS2L1 growth arrest specific 2 like 1 JBrowse link 14 46,449,767 46,455,278 RGD:14298760
G GAS2L2 growth arrest specific 2 like 2 JBrowse link 12 39,772,070 39,785,159 RGD:14298760
G GAS2L3 growth arrest specific 2 like 3 JBrowse link 5 83,558,816 83,600,725 RGD:14298760
G GAS7 growth arrest specific 7 JBrowse link 12 54,752,436 54,974,535 RGD:14298760
G GJB6 gap junction protein beta 6 JBrowse link 11 793,276 800,109 RGD:14298760
G GSN gelsolin JBrowse link 1 261,295,711 261,372,848 RGD:14298760
G GSN gelsolin RGD:14298760
G HCLS1 hematopoietic cell-specific Lyn substrate 1 JBrowse link 13 138,852,387 138,883,088 RGD:14298760
G HIP1 huntingtin interacting protein 1 JBrowse link 3 10,416,418 10,578,374 RGD:14298760
G HIP1R huntingtin interacting protein 1 related JBrowse link 14 29,996,388 30,024,343 RGD:14298760
G IQGAP2 IQ motif containing GTPase activating protein 2 JBrowse link 2 85,294,423 85,633,645 RGD:14298760
G IQGAP3 IQ motif containing GTPase activating protein 3 JBrowse link 4 93,495,999 93,556,915 RGD:14298760
G ITPRID2 ITPR interacting domain containing 2 JBrowse link 15 87,326,417 87,418,092 RGD:14298760
G KLHL17 kelch like family member 17 JBrowse link 6 63,320,898 63,328,093 RGD:9068941
G KPTN kaptin, actin binding protein JBrowse link 6 53,238,650 53,246,458 RGD:14298760
G LASP1 LIM and SH3 protein 1 JBrowse link 12 23,222,706 23,267,209 RGD:14298760
G LCP1 lymphocyte cytosolic protein 1 JBrowse link 11 21,126,504 21,223,543 RGD:14298760
G LIMA1 LIM domain and actin binding 1 JBrowse link 5 16,074,436 16,177,122 RGD:14298760
G LOC100513346 mitochondrial import inner membrane translocase subunit TIM16 JBrowse link 3 37,928,098 38,005,619 RGD:14298760
G LOC100620599 tropomyosin alpha-3 chain RGD:14298760
G LOC100736765 myosin-6 JBrowse link 7 75,677,666 75,704,486 RGD:14298760
G LOC110255887 myosin-8 JBrowse link 12 55,135,651 55,166,983 RGD:14298760
G LRPPRC leucine rich pentatricopeptide repeat containing JBrowse link 3 96,474,510 96,590,706 RGD:9068941
G MACF1 microtubule actin crosslinking factor 1 JBrowse link 6 94,960,385 95,318,126 RGD:14298760
G MACO1 macoilin 1 JBrowse link 6 82,934,083 82,995,688 RGD:14298760
G MAP1S microtubule associated protein 1S JBrowse link 2 60,003,116 60,043,133 RGD:14298760
RGD:9068941
G MARCKS myristoylated alanine rich protein kinase C substrate JBrowse link 1 79,789,796 79,795,895 RGD:14298760
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 JBrowse link 1 75,511,692 75,522,760 RGD:14298760
G MICALL2 MICAL like 2 JBrowse link 3 951,330 971,129 RGD:14298760
G MISP mitotic spindle positioning JBrowse link 2 77,607,185 77,619,124 RGD:14298760
G MPRIP myosin phosphatase Rho interacting protein JBrowse link 12 61,077,617 61,185,906 RGD:14298760
G MTSS1 MTSS I-BAR domain containing 1 JBrowse link 4 14,933,290 15,103,256 RGD:9068941
G MYH1 myosin, heavy chain 1, skeletal muscle, adult JBrowse link 12 55,225,581 55,251,495 RGD:14298760
G MYH10 myosin heavy chain 10 JBrowse link 12 53,647,579 53,781,552 RGD:14298760
RGD:9068941
G MYH11 myosin heavy chain 11 JBrowse link 3 7,002,667 7,143,093 RGD:14298760
G MYH13 myosin heavy chain 13 JBrowse link 12 55,051,990 55,103,415 RGD:14298760
G MYH14 myosin heavy chain 14 JBrowse link 6 55,097,851 55,200,754 RGD:14298760
RGD:9068941
G MYH15 myosin heavy chain 15 JBrowse link 13 151,008,571 151,156,933 RGD:14298760
G MYH2 myosin, heavy chain 2, skeletal muscle, adult JBrowse link 12 55,252,974 55,278,820 RGD:14298760
G MYH3 myosin heavy chain 3 JBrowse link 12 55,351,152 55,373,236 RGD:14298760
G MYH4 myosin, heavy chain 4, skeletal muscle JBrowse link 12 55,190,545 55,216,294 RGD:14298760
G MYH7 myosin heavy chain 7 JBrowse link 7 75,650,841 75,672,908 RGD:14298760
G MYH9 myosin heavy chain 9 JBrowse link 5 11,365,603 11,456,475 RGD:9068941
RGD:14298760
G MYL4 myosin light chain 4 JBrowse link 12 16,774,655 16,792,213 RGD:14298760
G MYO16 myosin XVI JBrowse link 11 75,739,783 76,271,958 RGD:14298760
G MYO19 myosin XIX JBrowse link 12 38,020,102 38,073,968 RGD:14298760
G MYO1A myosin IA JBrowse link 5 22,338,024 22,363,528 RGD:14298760
G MYO1B myosin IB JBrowse link 15 95,874,398 96,066,408 RGD:14298760
G MYO1C myosin IC JBrowse link 12 47,691,252 47,715,670 RGD:14298760
G MYO1D myosin ID JBrowse link 12 42,120,373 42,489,191 RGD:14298760
G MYO1E myosin IE JBrowse link 1 112,677,545 112,902,005 RGD:14298760
G MYO1F myosin IF JBrowse link 2 70,753,143 70,792,938 RGD:14298760
G MYO1G myosin IG JBrowse link 18 50,466,450 50,483,520 RGD:14298760
G MYO1H myosin IH JBrowse link 14 41,469,191 41,588,934 RGD:14298760
G MYO3A myosin IIIA JBrowse link 10 49,392,119 49,623,575 RGD:9068941
G MYO3B myosin IIIB JBrowse link 15 76,432,429 76,855,443 RGD:14298760
G MYO5A myosin VA JBrowse link 1 119,165,751 119,398,591 RGD:14298760
G MYO5B myosin VB JBrowse link 1 99,418,242 99,810,934 RGD:14298760
G MYO5C myosin VC JBrowse link 1 119,407,298 119,536,443 RGD:14298760
G MYO6 myosin VI JBrowse link 1 89,992,860 90,137,767 RGD:14298760
G MYO7A myosin VIIA JBrowse link 9 11,251,187 11,337,618 RGD:14298760
G MYO7B myosin VIIB JBrowse link 15 59,709,938 59,803,064 RGD:14298760
G MYO9A myosin IXA JBrowse link 1 169,370,028 169,596,771 RGD:14298760
G MYO9B myosin IXB JBrowse link 2 60,455,605 60,567,479 RGD:9068941
G NEB nebulin JBrowse link 15 546,187 766,131 RGD:14298760
G NEBL nebulette JBrowse link 10 53,602,929 53,957,869 RGD:14298760
G NEXN nexilin F-actin binding protein JBrowse link 6 135,315,000 135,382,911 RGD:14298760
G PANX1 pannexin 1 JBrowse link 9 26,443,425 26,491,010 RGD:14298760
G PDK2 pyruvate dehydrogenase kinase 2 JBrowse link 12 26,274,562 26,295,787 RGD:14298760
G PICK1 protein interacting with PRKCA 1 JBrowse link 5 9,808,444 9,829,677 RGD:9068941
G PKNOX2 PBX/knotted 1 homeobox 2 JBrowse link 9 52,303,022 52,608,505 RGD:14298760
G PLS1 plastin 1 JBrowse link 13 83,307,692 83,434,133 RGD:14298760
G PLS3 plastin 3 JBrowse link X 94,885,098 94,971,664 RGD:14298760
G POF1B POF1B actin binding protein JBrowse link X 68,503,170 68,579,917 RGD:14298760
G PPP1R9A protein phosphatase 1 regulatory subunit 9A JBrowse link 9 74,635,285 74,944,050 RGD:14298760
G PPP1R9B protein phosphatase 1 regulatory subunit 9B JBrowse link 12 26,319,123 26,337,089 RGD:14298760
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 JBrowse link 7 57,100,212 57,145,278 RGD:14298760
G PVALEF parvalbumin like EF-hand containing RGD:14298760
G RCSD1 RCSD domain containing 1 JBrowse link 4 83,322,175 83,404,102 RGD:9068941
G SCIN scinderin JBrowse link 9 82,103,271 82,185,254 RGD:14298760
G SHROOM1 shroom family member 1 JBrowse link 2 135,147,828 135,152,540 RGD:14298760
G SHROOM2 shroom family member 2 JBrowse link X
Y
6,296,212
4,753,733
6,450,401
4,785,766
RGD:14298760
G SHROOM4 shroom family member 4 JBrowse link X 44,301,956 44,543,969 RGD:14298760
G SHTN1 shootin 1 JBrowse link 14 127,065,507 127,175,222 RGD:9068941
G SIPA1L1 signal induced proliferation associated 1 like 1 JBrowse link 7 94,789,794 95,168,728 RGD:9068941
G SLC6A4 solute carrier family 6 member 4 JBrowse link 12 46,285,995 46,328,377 RGD:9068941
G SPTB spectrin beta, erythrocytic JBrowse link 7 88,812,717 88,954,471 RGD:14298760
G SPTBN5 spectrin beta, non-erythrocytic 5 JBrowse link 1 129,461,598 129,514,380 RGD:9068941
G SVIL supervillin JBrowse link 10 41,176,358 41,462,750 RGD:14298760
G SYNE1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1 13,715,644 14,201,711 RGD:9068941
G SYNE2 spectrin repeat containing nuclear envelope protein 2 JBrowse link 1 193,909,563 194,352,550 RGD:14298760
G SYNE3 spectrin repeat containing nuclear envelope family member 3 JBrowse link 7 116,666,238 116,770,305 RGD:14298760
G TAGLN transgelin JBrowse link 9 44,561,756 44,567,385 RGD:14298760
G TLN1 talin 1 JBrowse link 1 236,416,041 236,450,978 RGD:14298760
G TLN2 talin 2 JBrowse link 1 109,208,663 109,680,663 RGD:14298760
G TMEM201 transmembrane protein 201 JBrowse link 6 69,973,378 69,998,548 RGD:14298760
G TMOD1 tropomodulin 1 JBrowse link 1 239,375,150 239,468,387 RGD:14298760
G TMOD4 tropomodulin 4 JBrowse link 4 98,074,380 98,079,346 RGD:14298760
G TNNC1 troponin C1, slow skeletal and cardiac type JBrowse link 13 34,591,571 34,594,320 RGD:14298760
G TNNC2 troponin C2, fast skeletal type JBrowse link 17 48,025,621 48,026,762 RGD:14298760
G TNNI3 troponin I3, cardiac type JBrowse link 6 59,366,828 59,377,490 RGD:9068941
G TPM1 tropomyosin 1 JBrowse link 1 108,986,981 109,016,090 RGD:14298760
G TPM2 tropomyosin 2 JBrowse link 1 236,402,249 236,410,390 RGD:14298760
G TPM3 tropomyosin 3 JBrowse link 4 95,542,329 95,572,946 RGD:14298760
G TPM4 tropomyosin 4 JBrowse link 2 61,453,721 61,476,781 RGD:14298760
G TRIOBP TRIO and F-actin binding protein JBrowse link 5 10,066,080 10,132,668 RGD:14298760
G TRPV4 transient receptor potential cation channel subfamily V member 4 JBrowse link 14 41,125,819 41,169,582 RGD:9068941
G TTN titin JBrowse link 15 84,226,953 84,501,320 RGD:9068941
G TULP1 TUB like protein 1 JBrowse link 7 31,362,670 31,379,948 RGD:14298760
G TWF1 twinfilin actin binding protein 1 JBrowse link 5 74,868,586 74,881,220 RGD:14298760
G TWF2 twinfilin actin binding protein 2 JBrowse link 13 34,361,294 34,370,997 RGD:14298760
G USH1C USH1 protein network component harmonin JBrowse link 2 41,593,793 41,646,777 RGD:14298760
G UTRN utrophin JBrowse link 1 20,514,264 21,047,927 RGD:9068941
G UXT ubiquitously expressed prefoldin like chaperone JBrowse link X 42,176,142 42,184,131 RGD:9068941
G VCL vinculin JBrowse link 14 76,700,143 76,811,875 RGD:14298760
G VIL1 villin 1 JBrowse link 15 120,463,470 120,494,772 RGD:14298760
G VILL villin like JBrowse link 13 22,831,867 22,851,282 RGD:14298760
G VPS16 VPS16 core subunit of CORVET and HOPS complexes JBrowse link 17 32,803,596 32,825,974 RGD:9068941
G WDR1 WD repeat domain 1 JBrowse link 8 6,413,338 6,452,383 RGD:14298760
G XIRP1 xin actin binding repeat containing 1 JBrowse link 13 23,867,476 23,876,850 RGD:9068941
G XIRP2 xin actin binding repeat containing 2 JBrowse link 15 73,665,876 73,741,046 RGD:14298760
G ZNF185 zinc finger protein 185 with LIM domain JBrowse link X 123,942,981 123,988,102 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17332
    binding 15093
      protein-containing complex binding 1453
        actin filament binding 205
          actin lateral binding 0
Path 2
Term Annotations click to browse term
  molecular_function 17332
    binding 15093
      protein binding 13539
        cytoskeletal protein binding 939
          actin binding 387
            actin filament binding 205
              actin lateral binding 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.