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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament severing
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Accession:GO:0051014 term browser browse the term
Definition:The process in which an actin filament is broken down into smaller filaments.
Synonyms:exact_synonym: F-actin severing
 related_synonym: actin filament severing activity;   barbed-end actin capping/severing activity


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actin filament severing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07000276.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07029863.4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC093995.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Avil advillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:62,825,459...62,844,103 JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:104,594,743...104,611,856 JBrowse link
G Cfl1 cofilin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,796,012...202,801,337 JBrowse link
G Cfl2 cofilin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:72,355,664...72,359,709 JBrowse link
G Dbnl drebrin-like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) RGD PMID:10637315 MGI:1353214 NCBI chr14:80,666,115...80,681,155 JBrowse link
G Dstn destrin, actin depolymerizing factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:131,284,647...131,311,361 JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:45,394,032...45,408,051 JBrowse link
G Fmnl1 formin-like 1 involved_in ISO (MGI:5426775|PMID:21148482) RGD PMID:21148482 MGI:5426775 NCBI chr10:88,115,876...88,143,342 JBrowse link
G Gsn gelsolin involved_in IMP
ISO
IBA
ISS
(MGI:5619440|PMID:23325791)
PMID:21873635
(PMID:23575248), (PMID:3020431)
GO_REF:0000024
RGD
UniProt
PMID:3020431 PMID:23325791 PMID:23575248, PMID:11861757, PMID:21873635 GO_REF:0000024 MGI:5619440, RGD:1303950, RGD:13792537 NCBI chr 3:18,585,166...18,638,404 JBrowse link
G LOC102555366 cofilin-1-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:54,673,122...54,675,094 JBrowse link
G Scin scinderin involved_in ISO
IBA
(PMID:11568009)
PMID:21873635
RGD PMID:11568009, PMID:21873635 RGD:13792537 NCBI chr 6:57,110,128...57,188,059 JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 involved_in ISO
ISS
(PMID:21148482)
GO_REF:0000024
RGD
UniProt
PMID:21148482 GO_REF:0000024 NCBI chr13:42,745,956...42,967,083 JBrowse link
G Svil supervillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:52,648,502...52,844,114 JBrowse link
G Vil1 villin 1 involved_in IBA
ISO
PMID:21873635
(PMID:16921170), (PMID:17182858), (PMID:19808673)
RGD PMID:16921170 PMID:17182858 PMID:19808673, PMID:21873635 RGD:13792537 NCBI chr 9:75,991,141...76,018,860 JBrowse link
G Vill villin-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,776,718...118,794,983 JBrowse link
actin filament debranching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmfb glia maturation factor, beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:20,069,923...20,081,005 JBrowse link
G Gmfg glia maturation factor, gamma involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
(MGI:5505367|PMID:23727094)
PMID:21873635
Ensembl
RGD
PMID:23727094, PMID:21873635 GO_REF:0000107 MGI:5505367, RGD:13792537 NCBI chr 1:83,728,797...83,739,189 JBrowse link
negative regulation of actin filament severing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csrp3 cysteine and glycine rich protein 3 acts_upstream_of_or_within ISO (PMID:24860983) RGD PMID:24860983 NCBI chr 1:98,528,067...98,546,647 JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO (PMID:23325791)
(MGI:5619440|PMID:23325791)
RGD PMID:23325791 MGI:5619440 NCBI chr 7:109,343,718...109,424,457 JBrowse link
positive regulation of actin filament severing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csrp3 cysteine and glycine rich protein 3 acts_upstream_of_or_within ISO (PMID:24860983) RGD PMID:24860983 NCBI chr 1:98,528,067...98,546,647 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      actin filament-based process 833
        actin filament severing 22
          actin filament debranching 2
          negative regulation of actin filament severing 2
          positive regulation of actin filament severing 1
          regulation of actin filament severing + 2
paths to the root