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ONTOLOGY REPORT - ANNOTATIONS

Term:microtubule severing
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Accession:GO:0051013 term browser browse the term
Definition:The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.
Synonyms:related_synonym: microtubule severing activity


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microtubule severing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Katna1 katanin catalytic subunit A1 involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000117
MGI:2683461 (MGI:4819643|PMID:20530212)		 UniProt
RGD		 PMID:20530212 PMID:15944385 PMID:21873635 GO_REF:0000117 MGI:4819643, RGD:2316489, RGD:13792537 NCBI chr 1:2,202,501...2,244,132
Ensembl chr 1:2,202,490...2,244,131 		JBrowse link
G Katnal1 katanin catalytic subunit A1 like 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS		 (PMID:26929214)
PMID:21873635
(MGI:5427753|PMID:22654668)
GO_REF:0000024		 RGD
UniProt		 PMID:22654668 PMID:26929214 PMID:21873635 GO_REF:0000024 MGI:5427753, RGD:13792537 NCBI chr12:6,094,663...6,156,114
Ensembl chr12:6,102,836...6,157,553 		JBrowse link
G Katnal2 katanin catalytic subunit A1 like 2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:70,531,759...70,607,886
Ensembl chr18:70,531,754...70,608,082 		JBrowse link
G Katnb1 katanin regulatory subunit B1 IDA RGD PMID:15944385 RGD:2316489 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650 		JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423 		JBrowse link
G Spast spastin involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
MGI:1921660|MGI:2683461 (MGI:4819643|PMID:20530212)
(PMID:15716377), (PMID:16219033), (PMID:17389232), (PMID:21310966), (PMID:23745751), (PMID:26875866)
GO_REF:0000104		 UniProt
RGD		 PMID:15716377 PMID:16219033 PMID:17389232 PMID:20530212 PMID:21310966 More... GO_REF:0000024 GO_REF:0000104 MGI:4819643 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954 		JBrowse link
G Ttll11 tubulin tyrosine ligase like11 acts_upstream_of_or_within ISO MGI:1858896 (MGI:4819643|PMID:20530212) RGD PMID:20530212 MGI:4819643 NCBI chr 3:19,109,891...19,335,077
Ensembl chr 3:19,110,284...19,335,969 		JBrowse link
G Ttll6 tubulin tyrosine ligase like 6 acts_upstream_of_or_within ISO MGI:1344353|MGI:1858896 (MGI:4819643|PMID:20530212) RGD PMID:20530212 MGI:4819643 NCBI chr10:81,081,985...81,118,009
Ensembl chr10:81,091,975...81,127,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      microtubule-based process 950
        microtubule cytoskeleton organization 647
          microtubule severing 8
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          organelle organization 3900
            cytoskeleton organization 1494
              microtubule cytoskeleton organization 647
                microtubule severing 8
paths to the root