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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of nitric-oxide synthase activity
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Accession:GO:0050999 term browser browse the term
Definition:Any process that modulates the activity of the enzyme nitric-oxide synthase.
Synonyms:exact_synonym: NOS regulator;   nitric-oxide synthase regulator;   regulation of NOS activity


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regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A ISO
IEA
MGI:MGI:1861779 (MGI:MGI:3691726|PMID:16093358)
GO_REF:0000107
RGD
Ensembl
PMID:16093358 GO_REF:0000107, MGI:MGI:3691726 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:12828935) RGD PMID:12828935 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Il1a interleukin 1 alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:5705224|PMID:15899045)
(PMID:15899045)
Ensembl
RGD
PMID:15899045, PMID:21873635 GO_REF:0000107, MGI:MGI:5705224, RGD:13792537 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Lep leptin ISO
ISS
(PMID:15899045)
GO_REF:0000024
(MGI:MGI:5705224|PMID:15899045)
RGD
UniProt
PMID:15899045 GO_REF:0000024, MGI:MGI:5705224 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein IC
TAS
PMID:9459447
PMID:20431962
UniProt
DFLAT
PMID:9459447, PMID:20431962 RGD:632364, RGD:8553554 NCBI chr13:88,653,123...88,943,976 JBrowse link
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:11591728), (PMID:17242280), (PMID:19278978), (PMID:19287093) RGD PMID:11591728, PMID:17242280, PMID:19278978, PMID:19287093 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
MGI:MGI:2154537 (MGI:MGI:3612726|PMID:16380094), (MGI:MGI:3832129|PMID:18951881)
Ensembl
RGD
PMID:16380094, PMID:18951881 GO_REF:0000107, MGI:MGI:3612726, MGI:MGI:3832129 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav3 caveolin 3 ISO MGI:MGI:2180562 (MGI:MGI:1930012|PMID:11159934) RGD PMID:11159934 MGI:MGI:1930012 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Eng endoglin ISO (PMID:18974388) RGD PMID:18974388 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Gla galactosidase, alpha ISO (MGI:MGI:3624267|PMID:15668341) RGD PMID:15668341 MGI:MGI:3624267 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:18005341 RGD:10045554 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Nosip nitric oxide synthase interacting protein ISO (PMID:11149895) RGD PMID:11149895 NCBI chr 1:101,055,571...101,072,938
Ensembl chr 1:101,055,622...101,072,938
JBrowse link
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO (MGI:MGI:4399018|PMID:17000928) RGD PMID:17000928 MGI:MGI:4399018 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:10376603) RGD PMID:10376603 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Apoe apolipoprotein E ISO
IBA
IEA
(PMID:8995232)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8995232, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Calm1 calmodulin 1 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Dhfr dihydrofolate reductase ISO (MGI:MGI:5645206|PMID:19666465) RGD PMID:19666465 MGI:MGI:5645206 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Esr1 estrogen receptor 1 ISO
ISS
(PMID:21937726)
GO_REF:0000024
RGD
UniProt
PMID:21937726 GO_REF:0000024 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fcer2 Fc fragment of IgE receptor II ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:2,233,772...2,245,324
Ensembl chr12:2,233,778...2,245,324
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:12176133), (PMID:15721862), (PMID:17717598), (PMID:19666465) RGD PMID:12176133, PMID:15721862, PMID:17717598, PMID:19666465 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15625277)
Ensembl
UniProt
RGD
PMID:15625277 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G LOC103694380 tumor necrosis factor-like IC PMID:29702085 ARUK-UCL PMID:29702085 RGD:13800534 NCBI chr20:4,855,792...4,858,447
Ensembl chr20:4,855,829...4,858,447
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:22870324 RGD:9831169 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA PMID:9843699 BHF-UCL PMID:9843699 RGD:8554308 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO (PMID:28602162) RGD PMID:28602162 NCBI chr20:33,557,052...33,584,011
Ensembl chr20:33,557,052...33,584,010
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP
ISO
(MGI:MGI:3810237|PMID:17698736) RGD PMID:17698736, PMID:21926342 MGI:MGI:3810237, RGD:10041069 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G S100a1 S100 calcium binding protein A1 ISO (PMID:24244340) RGD PMID:24244340 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO (PMID:11792700) RGD PMID:11792700 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tert telomerase reverse transcriptase ISO (PMID:11927518) RGD PMID:11927518 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tnf tumor necrosis factor IC
IMP
PMID:29702085 ARUK-UCL
RGD
PMID:29702085, PMID:9537427 RGD:13800534, RGD:14985259 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      regulation of metabolic process 7007
        regulation of oxidoreductase activity 102
          regulation of monooxygenase activity 49
            regulation of nitric-oxide synthase activity 38
              negative regulation of nitric-oxide synthase activity 10
              positive regulation of nitric-oxide synthase activity 22
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of metabolic process 7007
          regulation of oxidoreductase activity 102
            regulation of monooxygenase activity 49
              regulation of nitric-oxide synthase activity 38
                negative regulation of nitric-oxide synthase activity 10
                positive regulation of nitric-oxide synthase activity 22
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.