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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of nitric-oxide synthase activity
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Accession:GO:0050999 term browser browse the term
Definition:Any process that modulates the activity of the enzyme nitric-oxide synthase.
Synonyms:exact_synonym: NOS regulator;   nitric-oxide synthase regulator;   regulation of NOS activity


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regulation of nitric-oxide synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861779 (MGI:3691726|PMID:16093358)		 Ensembl
RGD		 PMID:16093358 GO_REF:0000107 MGI:3691726 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:12828935) RGD PMID:12828935 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Il1a interleukin 1 alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IBA		 (PMID:15899045)
(MGI:5705224|PMID:15899045)
PMID:21873635		 RGD PMID:15899045 PMID:21873635 MGI:5705224, RGD:13792537 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Lep leptin involved_in ISO
ISS		 (PMID:15899045)
(MGI:5705224|PMID:15899045)
GO_REF:0000024		 RGD
UniProt		 PMID:15899045 GO_REF:0000024 MGI:5705224 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein involved_in IC
TAS		 PMID:9459447
PMID:20431962		 UniProt
DFLAT		 PMID:9459447 PMID:20431962 RGD:632364, RGD:8553554 NCBI chr13:82,549,786...82,820,949
Ensembl chr13:82,530,577...82,820,949 		JBrowse link
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:11591728), (PMID:17242280), (PMID:19278978), (PMID:19287093) RGD PMID:11591728 PMID:17242280 PMID:19278978 PMID:19287093 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2154537 (MGI:3612726|PMID:16380094), (MGI:3832129|PMID:18951881) RGD PMID:16380094 PMID:18951881 MGI:3612726 MGI:3832129 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180562 (MGI:1930012|PMID:11159934) RGD PMID:11159934 MGI:1930012 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Eng endoglin involved_in ISO (PMID:18974388) RGD PMID:18974388 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Gla galactosidase, alpha involved_in ISO (MGI:3624267|PMID:15668341) RGD PMID:15668341 MGI:3624267 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:18005341 RGD:10045554 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mir132 microRNA 132 involved_in ISO (PMID:28089352) RGD PMID:28089352 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:24244340) RGD PMID:24244340 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:24244340) RGD PMID:24244340 NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274 		JBrowse link
G Mir212 microRNA 212 involved_in ISO (PMID:28089352) RGD PMID:28089352 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:28602162) RGD PMID:28602162 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Nosip nitric oxide synthase interacting protein involved_in ISO (PMID:11149895) RGD PMID:11149895 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650 		JBrowse link
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (MGI:4399018|PMID:17000928) RGD PMID:17000928 MGI:4399018 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:10376603) RGD PMID:10376603 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apoe apolipoprotein E involved_in IBA
ISO
IEA		 PMID:21873635
(PMID:8995232)
GO_REF:0000107		 RGD
Ensembl		 PMID:8995232 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Calm1 calmodulin 1 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (MGI:5645206|PMID:19666465) RGD PMID:19666465 MGI:5645206 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Esr1 estrogen receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21937726)		 UniProt
RGD		 PMID:21937726 GO_REF:0000024 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fcer2 Fc epsilon receptor II involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:12176133), (PMID:15721862), (PMID:17717598), (PMID:19666465) RGD PMID:12176133 PMID:15721862 PMID:17717598 PMID:19666465 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO
ISS
IEA		 (PMID:15625277)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15625277 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:22870324 RGD:9831169 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Npr3 natriuretic peptide receptor 3 involved_in IDA PMID:9843699 BHF-UCL PMID:9843699 RGD:8554308 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit involved_in ISO (PMID:28602162) RGD PMID:28602162 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta acts_upstream_of ISO (PMID:18558630) RGD PMID:18558630 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO		 (MGI:3810237|PMID:17698736) RGD PMID:17698736 PMID:21926342 MGI:3810237, RGD:10041069 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G S100a1 S100 calcium binding protein A1 involved_in ISO (PMID:24244340) RGD PMID:24244340 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (PMID:11792700) RGD PMID:11792700 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:11927518) RGD PMID:11927518 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in IMP
IC		 PMID:29702085 RGD
ARUK-UCL		 PMID:9537427 PMID:29702085 RGD:14985259, RGD:13800534 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    biological regulation 13573
      regulation of molecular function 2736
        regulation of catalytic activity 1903
          regulation of oxidoreductase activity 114
            regulation of monooxygenase activity 57
              regulation of nitric-oxide synthase activity 43
                negative regulation of nitric-oxide synthase activity 15
                positive regulation of nitric-oxide synthase activity 22
paths to the root