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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of lipid catabolic process
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Accession:GO:0050994 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
Synonyms:exact_synonym: regulation of lipid breakdown;   regulation of lipid catabolism;   regulation of lipid degradation


show annotations for term's descendants           Sort by:
regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RARRES2 retinoic acid receptor responder 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 7:141,953,600...141,956,991
Ensembl chr 7:154,106,275...154,109,635 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (PMID:31442424) UniProt PMID:31442424 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126 		JBrowse link
G THRA thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12869545) Ensembl
MGI		 PMID:12869545 GO_REF:0000107 NCBI chr17:17,196,459...17,226,263 JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23209793) Ensembl
ARUK-UCL		 PMID:23209793 GO_REF:0000107 NCBI chr 1:39,244,438...39,259,156
Ensembl chr 1:40,569,706...40,584,438 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:22532565)
(PMID:21885430), (PMID:22675471)		 UniProt PMID:21885430 PMID:22532565 PMID:22675471 NCBI chr19:3,542,675...3,555,611 JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:54,570,372...54,586,751
Ensembl chr12:57,161,781...57,172,705 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:10948198) BHF-UCL PMID:10948198 NCBI chr10:107,669,860...107,673,685 JBrowse link
G ALK ALK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:29,196,195...29,930,062
Ensembl chr2A:29,276,041...30,006,735 		JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chr11:58,046,842...58,064,219
Ensembl chr11:61,399,314...61,416,494 		JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (PMID:15919794)
(PMID:12910269)
(PMID:26118629)		 BHF-UCL
UniProt		 PMID:12910269 PMID:15919794 PMID:26118629 NCBI chr18:2,051,880...2,075,909 JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107 		JBrowse link
G CRTC3 CREB regulated transcription coactivator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21164481) Ensembl
MGI		 PMID:21164481 GO_REF:0000107 NCBI chr15:69,217,679...69,333,897
Ensembl chr15:88,427,468...88,533,593 		JBrowse link
G ENDOU endonuclease, poly(U) specific involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:41,003,037...41,024,127
Ensembl chr12:41,882,483...41,897,119 		JBrowse link
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog acts_upstream_of_or_within ISO (PMID:25912136) MGI PMID:25912136 NCBI chr 7:131,289,119...131,295,330 JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:18465680 RGD:2293508 NCBI chr 7:142,319,479...142,326,035 JBrowse link
G HCAR1 hydroxycarboxylic acid receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:120,330,294...120,335,425
Ensembl chr12:124,567,699...124,568,739 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chr12:120,305,297...120,308,463 JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G INS insulin involved_in ISO (PMID:24675707) AgBase PMID:24675707 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G LOC100994952 apolipoprotein C-I, acidic form involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:41,862,168...41,878,231 JBrowse link
G PDE3B phosphodiesterase 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PLIN1 perilipin 1 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chr15:68,357,815...68,375,062
Ensembl chr15:87,565,468...87,577,301 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:21885430) UniProt PMID:21885430 NCBI chr19:3,542,675...3,555,611 JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chr19:3,542,675...3,555,611 JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
positive regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,275,165...143,295,283
Ensembl chr  X:153,162,412...153,182,424 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,082,122...49,158,524
Ensembl chr12:49,941,914...50,011,140 		JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:14711823 RGD:2312802 NCBI chr10:108,965,559...109,019,240
Ensembl chr10:112,407,161...112,457,892 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:19302064 RGD:2311346 NCBI chr11:63,841,028...63,928,242
Ensembl chr11:67,144,736...67,205,481 		JBrowse link
G FABP1 fatty acid binding protein 1 ISO peroxisomal RGD PMID:16262600 RGD:1626442 NCBI chr2A:87,256,032...87,303,505
Ensembl chr2A:89,165,315...89,170,448 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967 		JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chr13:90,886,095...90,917,724 JBrowse link
G MTLN mitoregulin involved_in ISO (PMID:29949755) UniProt PMID:29949755 NCBI chr2A:91,481,706...91,514,106
Ensembl chr2A:111,713,514...111,713,933 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO PMID:22127648
(PMID:17130488)		 UniProt PMID:17130488 PMID:22127648 RGD:8553692 NCBI chr19:3,542,675...3,555,611 JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20007935) BHF-UCL PMID:20007935 NCBI chr 7:19,761,041...19,765,665 JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
positive regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:43,580,752...43,612,637
Ensembl chr 3:44,640,215...44,669,885 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:9597368 RGD:1625365 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ANGPTL3 angiopoietin like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:61,855,870...61,863,476
Ensembl chr 1:63,670,516...63,679,194 		JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:8640403) BHF-UCL PMID:8640403 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G CLSTN3 calsyntenin 3 involved_in ISO (PMID:36477540) UniProt PMID:36477540 NCBI chr12:7,260,361...7,288,903
Ensembl chr12:7,175,951...7,204,526 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19401415) Ensembl
MGI		 PMID:19401415 GO_REF:0000107 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313 		JBrowse link
G SAA2 serum amyloid A2 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chr11:18,280,393...18,283,913 JBrowse link
G SCT secretin involved_in ISO (PMID:30449620)
(PMID:24273196)		 UniProt PMID:24273196 PMID:30449620 NCBI chr11:632,073...634,296 JBrowse link
G SCTR secretin receptor involved_in ISO (PMID:24273196)
(PMID:30449620)		 UniProt PMID:24273196 PMID:30449620 NCBI chr2B:6,374,400...6,458,595
Ensembl chr2B:119,952,714...120,036,326 		JBrowse link
positive regulation of phospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC2 apolipoprotein C2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:41,892,954...41,896,461 JBrowse link
G APOC4 apolipoprotein C4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:41,889,099...41,892,546 JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (PMID:21177474) UniProt PMID:21177474 NCBI chr17:73,811,249...73,822,719
Ensembl chr17:79,347,505...79,359,349 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAC arylacetamide deacetylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:148,820,706...148,853,422
Ensembl chr 3:156,408,950...156,423,847 		JBrowse link
G ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:43,580,752...43,612,637
Ensembl chr 3:44,640,215...44,669,885 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G APOC2 apolipoprotein C2 involved_in ISO (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr19:41,892,954...41,896,461 JBrowse link
G APOH apolipoprotein H ISO RGD PMID:7078428 RGD:8554677 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G DAGLB diacylglycerol lipase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,995,425...7,034,279
Ensembl chr 7:6,605,250...6,634,169 		JBrowse link
G FGF21 fibroblast growth factor 21 ISO RGD PMID:23262585 RGD:10401916 NCBI chr19:45,755,466...45,758,472 JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:28469073 RGD:12910100 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G PNPLA2 patatin like phospholipase domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:838,339...844,035
Ensembl chr11:881,934...886,896 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:23296834) AgBase PMID:23296834 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:56,199,434...56,311,773
Ensembl chr2B:173,664,518...173,776,379 		JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,275,165...143,295,283
Ensembl chr  X:153,162,412...153,182,424 		JBrowse link
G LONP2 lon peptidase 2, peroxisomal involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,513,060...28,628,181
Ensembl chr16:47,405,018...47,511,124 		JBrowse link
G MLYCD malonyl-CoA decarboxylase ISO RGD PMID:10516138 RGD:1600797 NCBI chr16:64,520,860...64,537,955
Ensembl chr16:83,912,793...83,929,162 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:17142137 RGD:1625611 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G TYSND1 trypsin like peroxisomal matrix peptidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:66,609,736...66,619,838
Ensembl chr10:69,141,724...69,148,346 		JBrowse link
regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767 		JBrowse link
regulation of phospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 acts_upstream_of_or_within ISO (PMID:25218477) MGI PMID:25218477 NCBI chr2B:95,475,320...95,494,286
Ensembl chr2B:213,599,036...213,617,175 		JBrowse link
regulation of prostaglandin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPGD 15-hydroxyprostaglandin dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:166,716,386...166,749,225
Ensembl chr 4:178,949,137...178,982,910 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      metabolic process 10770
        catabolic process 2488
          regulation of catabolic process 1016
            regulation of lipid catabolic process 74
              negative regulation of lipid catabolic process + 33
              positive regulation of lipid catabolic process + 34
              regulation of butyryl-CoA catabolic process to butanol + 0
              regulation of butyryl-CoA catabolic process to butyrate + 0
              regulation of fatty acid beta-oxidation + 23
              regulation of glucocorticoid catabolic process + 0
              regulation of glucosylceramide catabolic process + 1
              regulation of juvenile hormone catabolic process + 0
              regulation of palmitic acid catabolic process + 0
              regulation of phospholipid catabolic process + 8
              regulation of prostaglandin catabolic process + 1
              regulation of triglyceride catabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        regulation of cellular process 10895
          regulation of metabolic process 6441
            regulation of primary metabolic process 5328
              regulation of lipid metabolic process 359
                regulation of lipid catabolic process 74
                  negative regulation of lipid catabolic process + 33
                  positive regulation of lipid catabolic process + 34
                  regulation of butyryl-CoA catabolic process to butanol + 0
                  regulation of butyryl-CoA catabolic process to butyrate + 0
                  regulation of fatty acid beta-oxidation + 23
                  regulation of glucocorticoid catabolic process + 0
                  regulation of glucosylceramide catabolic process + 1
                  regulation of juvenile hormone catabolic process + 0
                  regulation of palmitic acid catabolic process + 0
                  regulation of phospholipid catabolic process + 8
                  regulation of prostaglandin catabolic process + 1
                  regulation of triglyceride catabolic process + 16
paths to the root