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ONTOLOGY REPORT - ANNOTATIONS

Term:pigment cell differentiation
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Accession:GO:0050931 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.
Comment:Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.
Synonyms:exact_synonym: chromatophore differentiation;   pigmented cell differentiation
 alt_id: GO:0043357;   GO:0043358

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pigment cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd63 CD63 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:196,002...199,177
Ensembl chrNW_004936646:191,128...199,777 		JBrowse link
endosome to melanosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd27 ankyrin repeat domain 27 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:3,044,565...3,097,692
Ensembl chrNW_004936570:3,044,565...3,098,097 		JBrowse link
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:21,983,248...22,063,133
Ensembl chrNW_004936475:21,983,248...22,063,181 		JBrowse link
G Ap1m1 adaptor related protein complex 1 subunit mu 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:4,322,032...4,347,392
Ensembl chrNW_004936596:4,318,452...4,347,392 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:1,223,646...1,262,577
Ensembl chrNW_004936588:1,222,466...1,262,676 		JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex 1 subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:1,702,154...1,704,366
Ensembl chrNW_004936706:1,684,824...1,706,544 		JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:4,550,592...4,584,482
Ensembl chrNW_004936534:4,550,592...4,584,482 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:8,209,091...8,226,249
Ensembl chrNW_004936471:8,209,057...8,226,353 		JBrowse link
G Cd63 CD63 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:196,002...199,177
Ensembl chrNW_004936646:191,128...199,777 		JBrowse link
G Rab32 RAB32, member RAS oncogene family involved_in ISO (PMID:22511774) ParkinsonsUK-UCL PMID:22511774 NCBI chrNW_004936489:35,620...51,809 JBrowse link
G Rab38 RAB38, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936736:1,304,290...1,360,412
Ensembl chrNW_004936736:1,304,185...1,361,221 		JBrowse link
erythrophore differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod2 superoxide dismutase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15205258) Ensembl
MGI		 PMID:15205258 GO_REF:0000107 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781 		JBrowse link
melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif 20 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18454205) Ensembl
MGI		 PMID:18454205 GO_REF:0000107 NCBI chrNW_004936512:1,942,902...2,088,122
Ensembl chrNW_004936512:1,943,196...2,088,122 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18454205) Ensembl
MGI		 PMID:18454205 GO_REF:0000107 NCBI chrNW_004936637:1,787,987...1,946,250
Ensembl chrNW_004936637:1,788,276...1,942,833 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12086670), (PMID:8758925)
(PMID:11709185)
(PMID:16427619)		 Ensembl
MGI		 PMID:8758925 PMID:11709185 PMID:12086670 PMID:16427619 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2379821) Ensembl
MGI		 PMID:2379821 GO_REF:0000107 NCBI chrNW_004936471:8,209,091...8,226,249
Ensembl chrNW_004936471:8,209,057...8,226,353 		JBrowse link
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936762:1,387,354...1,392,955
Ensembl chrNW_004936762:1,387,346...1,391,967 		JBrowse link
G Edn3 endothelin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9012511) Ensembl
MGI		 PMID:9012511 GO_REF:0000107 NCBI chrNW_004936530:1,744,216...1,766,602
Ensembl chrNW_004936530:1,744,199...1,765,027 		JBrowse link
G Ednrb endothelin receptor type B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:2379821)
(PMID:9012511)		 RGD
MGI
Ensembl		 PMID:2379821 PMID:9012511 PMID:11709437 GO_REF:0000107 RGD:628459 NCBI chrNW_004936511:3,446,864...3,478,434
Ensembl chrNW_004936511:3,446,839...3,478,434 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:28964717) UniProt PMID:28964717 NCBI chrNW_004937067:194,375...246,607 JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18397875) Ensembl
MGI		 PMID:18397875 GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630
Ensembl chrNW_004936478:17,126,911...17,403,011 		JBrowse link
G Hps1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:11836498) MGI PMID:11836498 NCBI chrNW_004936636:1,407,666...1,430,683
Ensembl chrNW_004936636:1,410,589...1,430,124 		JBrowse link
G Hps4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11836498) Ensembl
MGI		 PMID:11836498 GO_REF:0000107 NCBI chrNW_004936657:1,075,300...1,104,328
Ensembl chrNW_004936657:1,075,261...1,103,055 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274 		JBrowse link
G LOC101955772 olfactory receptor 51E2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:398,888...416,085
Ensembl chrNW_004936498:398,888...416,085 		JBrowse link
G Lrmda leucine rich melanocyte differentiation associated involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936521:2,959,770...3,637,431
Ensembl chrNW_004936521:2,959,844...3,946,191 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5049797|PMID:21610032) UniProt PMID:21610032 MGI:5049797 NCBI chrNW_004936469:7,060,480...7,225,497
Ensembl chrNW_004936469:7,060,480...7,204,661 		JBrowse link
G Mitf melanocyte inducing transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12086670)
(PMID:2379821)		 Ensembl
MGI
TreeGrafter		 PMID:2379821 PMID:12086670 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936603:1,682,411...1,858,295
Ensembl chrNW_004936603:1,682,513...1,858,173 		JBrowse link
G Mlph melanophilin acts_upstream_of_or_within ISO (PMID:11504925), (PMID:2379821) MGI PMID:2379821 PMID:11504925 NCBI chrNW_004936525:776,102...821,067
Ensembl chrNW_004936525:775,955...821,085 		JBrowse link
G Mreg melanoregulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2379821), (PMID:7828830) Ensembl
MGI
TreeGrafter		 PMID:2379821 PMID:7828830 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936586:1,203,520...1,261,341
Ensembl chrNW_004936586:1,203,367...1,261,421 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO (PMID:1996138), (PMID:2379821), (PMID:7828830) MGI PMID:1996138 PMID:2379821 PMID:7828830 NCBI chrNW_004936471:14,105,832...14,257,386
Ensembl chrNW_004936471:14,111,841...14,254,246 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2379821) Ensembl
MGI
TreeGrafter		 PMID:2379821 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:38,612,450...38,952,150
Ensembl chrNW_004936471:38,612,427...38,952,199 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2379821) Ensembl
MGI		 PMID:2379821 GO_REF:0000107 MGI:52947 NCBI chrNW_004936471:16,738,204...16,815,561
Ensembl chrNW_004936471:16,738,230...16,815,943 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936471:10,470,078...10,492,334
Ensembl chrNW_004936471:10,470,046...10,493,104 		JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16790476) Ensembl
MGI		 PMID:16790476 GO_REF:0000107 NCBI chrNW_004936492:3,173,770...3,183,423
Ensembl chrNW_004936492:3,173,741...3,185,024 		JBrowse link
G Tyrp1 tyrosinase related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2379821) Ensembl
MGI
TreeGrafter		 PMID:2379821 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936539:6,537,448...6,555,440
Ensembl chrNW_004936539:6,537,509...6,556,513 		JBrowse link
pigment cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamtsl4 ADAMTS like 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26405179) Ensembl
MGI		 PMID:26405179 GO_REF:0000107 NCBI chrNW_004936580:782,146...791,388
Ensembl chrNW_004936580:782,112...791,605 		JBrowse link
pigment granule maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd63 CD63 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:196,002...199,177
Ensembl chrNW_004936646:191,128...199,777 		JBrowse link
positive regulation of melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif 20 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18454205) Ensembl
MGI		 PMID:18454205 GO_REF:0000107 NCBI chrNW_004936512:1,942,902...2,088,122
Ensembl chrNW_004936512:1,943,196...2,088,122 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18454205) Ensembl
MGI		 PMID:18454205 GO_REF:0000107 NCBI chrNW_004936637:1,787,987...1,946,250
Ensembl chrNW_004936637:1,788,276...1,942,833 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16427619) Ensembl
MGI		 PMID:16427619 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Kitlg KIT ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16427619) Ensembl
MGI		 PMID:16427619 GO_REF:0000107 NCBI chrNW_004936507:5,566,144...5,650,412
Ensembl chrNW_004936507:5,565,821...5,650,828 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO (MGI:5574413|PMID:24769727) BHF-UCL PMID:24769727 MGI:5574413 NCBI chrNW_004936469:32,240,730...32,372,413
Ensembl chrNW_004936469:32,240,835...32,371,267 		JBrowse link
positive regulation of pigment cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:4,550,592...4,584,482
Ensembl chrNW_004936534:4,550,592...4,584,482 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:8,209,091...8,226,249
Ensembl chrNW_004936471:8,209,057...8,226,353 		JBrowse link
regulation of melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna11 G protein subunit alpha 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15322542) Ensembl
MGI		 PMID:15322542 GO_REF:0000107 NCBI chrNW_004936588:1,770,777...1,789,143
Ensembl chrNW_004936588:1,770,771...1,789,170 		JBrowse link
G LOC101971998 guanine nucleotide-binding protein G(q) subunit alpha acts_upstream_of_or_within ISO (PMID:15322542) MGI PMID:15322542 NCBI chrNW_004936503:13,098,517...13,276,106
Ensembl chrNW_004936503:13,099,558...13,276,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    pigmentation 103
      developmental pigmentation 54
        pigment cell differentiation 39
          compound eye pigment cell differentiation 0
          cyanophore differentiation + 0
          erythrophore differentiation + 1
          iridophore differentiation + 0
          leucophore differentiation + 0
          melanocyte differentiation + 28
          negative regulation of pigment cell differentiation + 0
          pigment cell development 1
          pigment granule maturation + 10
          positive regulation of pigment cell differentiation + 7
          regulation of pigment cell differentiation + 9
          xanthophore differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 15871
    cellular process 15001
      cellular developmental process 4251
        cell differentiation 4250
          pigment cell differentiation 39
            compound eye pigment cell differentiation 0
            cyanophore differentiation + 0
            erythrophore differentiation + 1
            iridophore differentiation + 0
            leucophore differentiation + 0
            melanocyte differentiation + 28
            negative regulation of pigment cell differentiation + 0
            pigment cell development 1
            pigment granule maturation + 10
            positive regulation of pigment cell differentiation + 7
            regulation of pigment cell differentiation + 9
            xanthophore differentiation + 0
paths to the root