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ONTOLOGY REPORT - ANNOTATIONS

Term:pigment cell differentiation
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Accession:GO:0050931 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.
Comment:Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.
Synonyms:exact_synonym: chromatophore differentiation;   pigmented cell differentiation
 alt_id: GO:0043357;   GO:0043358


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pigment cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd63 Cd63 molecule involved_in ISO
IEA 		(PMID:21962903)
GO_REF:0000107 		RGD
Ensembl		 PMID:21962903 GO_REF:0000107 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
endosome to melanosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd27 ankyrin repeat domain 27 involved_in ISO
IEA 		(PMID:21187829)
GO_REF:0000107 		RGD
Ensembl		 PMID:21187829 GO_REF:0000107 NCBI chr 1:88,251,216...88,303,615
Ensembl chr 1:88,251,226...88,303,615 		JBrowse link
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO
IEA 		(PMID:22511774)
GO_REF:0000107 		RGD
Ensembl		 PMID:22511774 GO_REF:0000107 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Ap1m1 adaptor related protein complex 1 subunit mu 1 involved_in ISO
IEA 		(PMID:19841138)
GO_REF:0000107 		RGD
Ensembl		 PMID:19841138 GO_REF:0000107 NCBI chr16:17,586,886...17,602,410
Ensembl chr16:17,584,730...17,602,403 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in ISO
IEA 		(PMID:22511774)
GO_REF:0000107 		RGD
Ensembl		 PMID:22511774 GO_REF:0000107 NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643 		JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 involved_in ISO
IEA 		(PMID:17182842)
GO_REF:0000107 		RGD
Ensembl		 PMID:17182842 GO_REF:0000107 NCBI chr 1:79,155,873...79,158,247
Ensembl chr 1:79,155,693...79,158,505 		JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 involved_in ISO (PMID:17182842) RGD PMID:17182842 NCBI chr17:26,171,965...26,197,276
Ensembl chr17:26,172,018...26,197,251 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17182842) 		UniProt
Ensembl
RGD		 PMID:17182842 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Cd63 Cd63 molecule involved_in ISO
IEA
ISS 		(PMID:21962903)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21962903 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
G Rab32 RAB32, member RAS oncogene family involved_in ISO (PMID:22511774) RGD PMID:22511774 NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934 		JBrowse link
G Rab38 RAB38, member RAS oncogene family involved_in ISO
IEA 		(PMID:22511774)
GO_REF:0000107 		RGD
Ensembl		 PMID:22511774 GO_REF:0000107 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
erythrophore differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA 		MGI:1857344 (PMID:15205258)
GO_REF:0000107 		RGD
Ensembl		 PMID:15205258 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 acts_upstream_of ISO
IEA 		MGI:1916320|MGI:3766915 (PMID:18454205)
GO_REF:0000107 		RGD
Ensembl		 PMID:18454205 GO_REF:0000107 NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 acts_upstream_of ISO
IEA 		MGI:2660628 (PMID:18454205)
GO_REF:0000107 		RGD
Ensembl		 PMID:18454205 GO_REF:0000107 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:104554|MGI:2156165|MGI:2158305 (PMID:11709185), (PMID:12086670), (PMID:8758925)
MGI:2158305 (PMID:16427619) 		RGD PMID:8758925 PMID:11709185 PMID:12086670 PMID:16427619 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO
IEA 		MGI:1856982 (PMID:2379821)
GO_REF:0000107 		RGD
Ensembl		 PMID:2379821 GO_REF:0000107 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISO
IEA
IBA
ISS 		(PMID:8901575)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:8901575 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Cited1l1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:204,760,742...204,761,351
Ensembl chr 1:204,760,188...204,761,398 		JBrowse link
G Edn3 endothelin 3 acts_upstream_of_or_within ISO (PMID:9012511) RGD PMID:9012511 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Ednrb endothelin receptor type B acts_upstream_of_or_within IDA
IEA
ISO 		GO_REF:0000107
MGI:1856148 (PMID:2379821), (PMID:9012511) 		Ensembl
RGD		 PMID:2379821 PMID:9012511 PMID:11709437 GO_REF:0000107, RGD:628459 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO
ISS 		(PMID:28964717)
GO_REF:0000024 		RGD
UniProt		 PMID:28964717 GO_REF:0000024 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G ENSRNOG00000066743 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:204,760,188...204,761,398 JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO
IEA 		MGI:3720956 (PMID:18397875)
GO_REF:0000107 		RGD
Ensembl		 PMID:18397875 GO_REF:0000107 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO MGI:1856712 (PMID:11836498) RGD PMID:11836498 NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268 		JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 acts_upstream_of_or_within ISO MGI:1856931 (PMID:11836498) RGD PMID:11836498 NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO
IEA 		(PMID:15768389)
GO_REF:0000107 		RGD
Ensembl		 PMID:15768389 GO_REF:0000107 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Lrmda leucine rich melanocyte differentiation associated involved_in ISO
IBA 		(PMID:23395477)
GO_REF:0000033 		RGD
GO_Central		 PMID:23395477 GO_REF:0000033 NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO 		GO_REF:0000024
(PMID:21610032) 		UniProt
RGD		 PMID:21610032 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mitf melanocyte inducing transcription factor involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:1856088|MGI:1856095|MGI:88138 (PMID:12086670), (PMID:2379821) 		GO_Central
Ensembl
RGD		 PMID:2379821 PMID:12086670 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mlph melanophilin acts_upstream_of_or_within ISO MGI:1856674 (PMID:11504925), (PMID:2379821) RGD PMID:2379821 PMID:11504925 NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983 		JBrowse link
G Mreg melanoregulin involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:1856847 (PMID:2379821), (PMID:7828830) 		GO_Central
Ensembl
RGD		 PMID:2379821 PMID:7828830 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:73,786,727...73,842,081
Ensembl chr 9:73,787,267...73,842,087 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856004 (PMID:1996138), (PMID:2379821), (PMID:7828830) RGD PMID:1996138 PMID:2379821 PMID:7828830 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		MGI:1856114 (PMID:2379821)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:2379821 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Olr59 olfactory receptor 59 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:27226631) 		Ensembl
UniProt
RGD		 PMID:27226631 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO
IEA 		MGI:1856656 (PMID:2379821)
GO_REF:0000107 		RGD
Ensembl		 PMID:2379821 GO_REF:0000107 MGI:52947 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Sox10 SRY-box transcription factor 10 acts_upstream_of_or_within ISO
IEA 		MGI:3701358 (PMID:16790476)
GO_REF:0000107 		RGD
Ensembl		 PMID:16790476 GO_REF:0000107 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:1855962 (PMID:2379821) 		GO_Central
Ensembl
RGD		 PMID:2379821 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
pigment cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamtsl4 ADAMTS-like 4 acts_upstream_of_or_within ISO
IEA 		(PMID:26405179)
GO_REF:0000107 		RGD
Ensembl		 PMID:26405179 GO_REF:0000107 NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848 		JBrowse link
pigment granule maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd63 Cd63 molecule involved_in ISO
IEA
ISS 		(PMID:21962903)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21962903 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
positive regulation of melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 acts_upstream_of_or_within ISO
IEA 		MGI:1916320|MGI:3766915 (PMID:18454205)
GO_REF:0000107 		RGD
Ensembl		 PMID:18454205 GO_REF:0000107 NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 acts_upstream_of_or_within ISO
IEA 		MGI:2660628 (PMID:18454205)
GO_REF:0000107 		RGD
Ensembl		 PMID:18454205 GO_REF:0000107 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:2158305 (PMID:16427619) RGD PMID:16427619 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO
IEA 		(PMID:16427619)
GO_REF:0000107 		RGD
Ensembl		 PMID:16427619 GO_REF:0000107 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO
IEA 		(PMID:24769727)
GO_REF:0000107 		RGD
Ensembl		 PMID:24769727 GO_REF:0000107 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
positive regulation of pigment cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 involved_in ISO (PMID:17182842) RGD PMID:17182842 NCBI chr17:26,171,965...26,197,276
Ensembl chr17:26,172,018...26,197,251 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:17182842)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:17182842 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
regulation of melanocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna11 G protein subunit alpha 11 acts_upstream_of_or_within ISO
IEA 		MGI:2682213 (PMID:15322542)
GO_REF:0000107 		RGD
Ensembl		 PMID:15322542 GO_REF:0000107 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q acts_upstream_of_or_within ISO MGI:2681766 (PMID:15322542) RGD PMID:15322542 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    pigmentation 110
      developmental pigmentation 56
        pigment cell differentiation 40
          compound eye pigment cell differentiation 0
          cyanophore differentiation + 0
          erythrophore differentiation + 1
          iridophore differentiation + 0
          leucophore differentiation + 0
          melanocyte differentiation + 29
          negative regulation of pigment cell differentiation + 0
          pigment cell development 1
          pigment granule maturation + 10
          positive regulation of pigment cell differentiation + 7
          regulation of pigment cell differentiation + 9
          xanthophore differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cellular developmental process 4838
        cell differentiation 4837
          pigment cell differentiation 40
            compound eye pigment cell differentiation 0
            cyanophore differentiation + 0
            erythrophore differentiation + 1
            iridophore differentiation + 0
            leucophore differentiation + 0
            melanocyte differentiation + 29
            negative regulation of pigment cell differentiation + 0
            pigment cell development 1
            pigment granule maturation + 10
            positive regulation of pigment cell differentiation + 7
            regulation of pigment cell differentiation + 9
            xanthophore differentiation + 0
paths to the root