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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chemotaxis
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Accession:GO:0050922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
Synonyms:exact_synonym: down regulation of chemotaxis;   downregulation of chemotaxis
 narrow_synonym: inhibition of chemotaxis



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negative regulation of chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036) BHF-UCL PMID:28759036 NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:3029644|PMID:14966296) UniProt PMID:14966296 MGI:3029644 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719
JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO RGD PMID:11559557 RGD:10043143 NCBI chr34:19,497,577...19,589,125
Ensembl chr34:19,497,922...19,586,427
JBrowse link
negative regulation of axon extension involved in axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 ISO RGD PMID:19884510 RGD:9681717 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G NRP1 neuropilin 1 acts_upstream_of_or_within ISO (MGI:1289520|PMID:9753685) RGD
MGI
PMID:9288754 PMID:9753685 MGI:1289520 RGD:633436 NCBI chr 2:3,416,062...3,553,929
Ensembl chr 2:3,413,821...3,552,483
JBrowse link
G PLXNA3 plexin A3 acts_upstream_of_or_within ISO (MGI:2152659|PMID:11683995) MGI PMID:11683995 MGI:2152659 NCBI chr  X:122,165,460...122,180,727
Ensembl chr  X:122,167,144...122,180,951
JBrowse link
G RYK receptor like tyrosine kinase acts_upstream_of_or_within ISO (MGI:3625635|PMID:16723543) MGI PMID:16723543 MGI:3625635 NCBI chr23:30,968,105...31,051,353
Ensembl chr23:30,968,231...31,051,605
JBrowse link
G SEMA3A semaphorin 3A involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1289520|PMID:9753685), (MGI:73216|PMID:7748561)
(MGI:3801368|PMID:18550718)
(MGI:2152659|PMID:11683995)
GO_Central
GO_Central
Ensembl
MGI
PMID:7748561 PMID:9753685 PMID:11683995 PMID:18550718 PMID:21873635 GO_REF:0000107 MGI:1289520 MGI:2152659 MGI:3801368 MGI:73216 NCBI chr18:23,411,607...23,866,631
Ensembl chr18:23,414,576...23,867,098
JBrowse link
G SEMA3B semaphorin 3B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:39,058,708...39,067,277
Ensembl chr20:39,059,245...39,065,661
JBrowse link
G SEMA3C semaphorin 3C involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr18:20,457,683...20,748,008
Ensembl chr18:20,459,925...20,635,276
JBrowse link
G SEMA3D semaphorin 3D involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr18:24,254,113...24,429,767
Ensembl chr18:24,262,125...24,394,155
JBrowse link
G SEMA3E semaphorin 3E involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr18:22,881,135...22,982,549
Ensembl chr18:22,881,133...23,116,696
JBrowse link
G SEMA3F semaphorin 3F acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:1289520|PMID:9753685)
(PMID:21873635)
(MGI:2152659|PMID:11683995)
MGI
Ensembl
GO_Central
GO_Central
PMID:9753685 PMID:11683995 PMID:21873635 GO_REF:0000107 MGI:1289520 MGI:2152659 NCBI chr20:39,135,580...39,165,381
Ensembl chr20:39,136,523...39,161,325
JBrowse link
G SEMA3G semaphorin 3G involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:37,322,531...37,334,333
Ensembl chr20:37,322,565...37,332,818
JBrowse link
G SEMA4A semaphorin 4A involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460
JBrowse link
G SEMA4B semaphorin 4B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:53,159,233...53,184,102
Ensembl chr 3:53,121,775...53,184,118
JBrowse link
G SEMA4C semaphorin 4C involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr10:45,105,701...45,116,504
Ensembl chr10:45,106,666...45,115,592
JBrowse link
G SEMA4D semaphorin 4D involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:96,825,963...96,878,956
Ensembl chr 1:96,814,674...96,878,968
JBrowse link
G SEMA4F ssemaphorin 4F involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:48,479,389...48,510,659
Ensembl chr17:48,479,659...48,506,660
JBrowse link
G SEMA4G semaphorin 4G involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr28:13,659,541...13,673,807
Ensembl chr28:13,662,686...13,672,359
JBrowse link
G SEMA5A semaphorin 5A involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr34:4,612,202...5,089,071
Ensembl chr34:4,612,142...5,082,280
JBrowse link
G SEMA5B semaphorin 5B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr33:25,971,178...26,041,842
Ensembl chr33:25,970,764...26,091,087
JBrowse link
G SEMA6A semaphorin 6A involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr11:6,117,063...6,245,443
Ensembl chr11:6,119,964...6,177,817
JBrowse link
G SEMA6B semaphorin 6B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:55,151,913...55,173,434
Ensembl chr20:55,161,818...55,173,135
JBrowse link
G SEMA6C semaphorin 6C involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:60,195,798...60,208,630
Ensembl chr17:60,195,785...60,208,630
JBrowse link
G SEMA6D semaphorin 6D involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr30:13,489,896...14,059,623
Ensembl chr30:14,005,124...14,057,202
JBrowse link
G SEMA7A semaphorin 7A involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr30:37,531,986...37,547,650
Ensembl chr30:37,531,971...37,566,645
JBrowse link
G SLIT1 slit guidance ligand 1 ISO RGD PMID:15632296 RGD:1358459 NCBI chr28:10,351,758...10,519,322
Ensembl chr28:10,351,821...10,519,313
JBrowse link
G WNT3 Wnt family member 3 acts_upstream_of_or_within ISO (MGI:3806438|PMID:18716223) MGI PMID:18716223 MGI:3806438 NCBI chr 9:10,073,019...10,124,454
Ensembl chr 9:10,077,567...10,124,508
JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within ISO (MGI:3806438|PMID:18716223) MGI PMID:18716223 MGI:3806438 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412
JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3625635|PMID:16723543) MGI
Ensembl
Ensembl
PMID:16723543 GO_REF:0000107 MGI:3625635 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
negative regulation of dendritic cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLAMF8 SLAM family member 8 acts_upstream_of_or_within ISO (MGI:5752697|PMID:25799045) MGI PMID:25799045 MGI:5752697 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096
JBrowse link
negative regulation of endothelial cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRG histidine rich glycoprotein involved_in ISO (PMID:14744774), (PMID:16436387), (PMID:16489009) UniProt PMID:14744774 PMID:16436387 PMID:16489009 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G THBS1 thrombospondin 1 acts_upstream_of_or_within ISO (PMID:16150726) MGI PMID:16150726 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
negative regulation of endothelial cell chemotaxis to fibroblast growth factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL13 C-X-C motif chemokine ligand 13 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr32:2,047,277...2,053,277
Ensembl chr32:2,047,315...2,052,833
JBrowse link
negative regulation of leukocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR18 G protein-coupled receptor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5629467|PMID:25348153) Ensembl
Ensembl
MGI
PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr22:49,288,226...49,294,567
Ensembl chr22:49,288,343...49,289,338
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO RGD PMID:15528323 RGD:2303400 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
negative regulation of lymphocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PADI2 peptidyl arginine deiminase 2 involved_in ISO (PMID:18645041) UniProt PMID:18645041 NCBI chr 2:81,116,031...81,147,889
Ensembl chr 2:81,116,140...81,145,043
JBrowse link
negative regulation of macrophage chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5 complement C5 involved_in ISO (PMID:14566334) BHF-UCL PMID:14566334 NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5610078|PMID:25447050) MGI
Ensembl
Ensembl
PMID:25447050 GO_REF:0000107 MGI:5610078 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353
JBrowse link
G DDT D-dopachrome tautomerase involved_in ISO (PMID:21817065) BHF-UCL PMID:21817065 NCBI chr26:28,520,189...28,522,539 JBrowse link
G MIF macrophage migration inhibitory factor involved_in ISO (PMID:21817065) BHF-UCL PMID:21817065
G MMP28 matrix metallopeptidase 28 acts_upstream_of_or_within ISO (MGI:3836320|PMID:19265166) MGI PMID:19265166 MGI:3836320 NCBI chr 9:37,873,364...37,907,724
Ensembl chr 9:37,884,430...37,907,719
JBrowse link
G SLAMF8 SLAM family member 8 acts_upstream_of_or_within ISO (MGI:5752697|PMID:25799045) MGI PMID:25799045 MGI:5752697 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711
JBrowse link
negative regulation of mast cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIN3 Ras and Rab interactor 3 acts_upstream_of ISO (PMID:23185384) ARUK-UCL PMID:23185384 NCBI chr 8:1,733,051...1,804,138
Ensembl chr 8:1,700,161...1,803,950
JBrowse link
negative regulation of monocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:18,507,586...18,515,755
Ensembl chr13:18,507,580...18,514,619
JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in ISO (PMID:22991462) BHF-UCL PMID:22991462 NCBI chr 4:39,588,833...39,591,065
Ensembl chr 4:39,588,339...39,590,514
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in ISO (MGI:5318030|PMID:15528323) BHF-UCL PMID:15528323 MGI:5318030 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820
JBrowse link
G SLAMF8 SLAM family member 8 acts_upstream_of_or_within ISO (MGI:5752697|PMID:25799045) MGI PMID:25799045 MGI:5752697 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
negative regulation of natural killer cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 involved_in ISO (PMID:7545673) UniProt PMID:7545673 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882
JBrowse link
G LOC100687968 C-type lectin domain family 2 member F-like involved_in ISO (PMID:22585739) CACAO PMID:22585739 NCBI chr27:36,059,707...36,068,092 JBrowse link
negative regulation of negative chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728
JBrowse link
G ROBO2 roundabout guidance receptor 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr31:9,415,390...11,047,710
Ensembl chr31:9,419,026...11,022,392
JBrowse link
negative regulation of neutrophil chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5AR2 complement C5a receptor 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:108,644,195...108,652,628
Ensembl chr 1:108,644,945...108,645,958
JBrowse link
G DPP4 dipeptidyl peptidase 4 involved_in ISO (PMID:23677473) CACAO PMID:23677473 NCBI chr36:7,398,713...7,472,554
Ensembl chr36:7,399,643...7,454,204
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 involved_in ISO (PMID:24501198) UniProt PMID:24501198 NCBI chr19:52,607,598...52,623,799
Ensembl chr19:52,607,713...52,623,811
JBrowse link
negative regulation of positive chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT2 angiopoietin 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:58,404,049...58,458,344
Ensembl chr16:58,405,259...58,457,701
JBrowse link
negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
negative regulation of smooth muscle cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIF1 allograft inflammatory factor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177
JBrowse link
G CORO1B coronin 1B involved_in ISO PMID:22619279
(PMID:22619279)
UniProt PMID:22619279 RGD:10047170 NCBI chr18:50,027,274...50,031,601
Ensembl chr18:50,027,275...50,050,907
JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:24321768 RGD:10401938 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16237
    locomotion 1920
      negative regulation of locomotion 349
        negative regulation of chemotaxis 62
          negative regulation of Schwann cell chemotaxis 0
          negative regulation of astrocyte chemotaxis 0
          negative regulation of axon extension involved in axon guidance 28
          negative regulation of axon guidance + 1
          negative regulation of cell chemotaxis to fibroblast growth factor + 1
          negative regulation of chemokine activity 0
          negative regulation of chemotaxis to arachidonic acid 0
          negative regulation of endothelial cell chemotaxis + 4
          negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
          negative regulation of fibroblast chemotaxis 0
          negative regulation of leukocyte chemotaxis + 21
          negative regulation of muscle cell chemotaxis toward tendon cell 0
          negative regulation of negative chemotaxis + 2
          negative regulation of positive chemotaxis + 1
          negative regulation of smooth muscle cell chemotaxis 4
Path 2
Term Annotations click to browse term
  biological_process 16237
    biological regulation 11773
      regulation of biological process 11134
        regulation of response to stimulus 3808
          regulation of response to external stimulus 953
            regulation of chemotaxis 243
              negative regulation of chemotaxis 62
                negative regulation of Schwann cell chemotaxis 0
                negative regulation of astrocyte chemotaxis 0
                negative regulation of axon extension involved in axon guidance 28
                negative regulation of axon guidance + 1
                negative regulation of cell chemotaxis to fibroblast growth factor + 1
                negative regulation of chemokine activity 0
                negative regulation of chemotaxis to arachidonic acid 0
                negative regulation of endothelial cell chemotaxis + 4
                negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
                negative regulation of fibroblast chemotaxis 0
                negative regulation of leukocyte chemotaxis + 21
                negative regulation of muscle cell chemotaxis toward tendon cell 0
                negative regulation of negative chemotaxis + 2
                negative regulation of positive chemotaxis + 1
                negative regulation of smooth muscle cell chemotaxis 4
paths to the root