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ONTOLOGY REPORT - ANNOTATIONS


Term:diapedesis
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Accession:GO:0050904 term browser browse the term
Definition:The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
Comment:Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic.


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diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd99l2 CD99 molecule-like 2 acts_upstream_of_or_within ISO (MGI:5467432|PMID:23293350) RGD PMID:23293350 MGI:5467432 NCBI chr15:5,265,257...5,311,232
Ensembl chr15:5,265,307...5,311,233
Ensembl chr15:5,265,307...5,311,233
JBrowse link
G Fer FER tyrosine kinase involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5319615|PMID:16009680)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16009680 GO_REF:0000024 GO_REF:0000107 MGI:5319615 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670
JBrowse link
G Itga4 integrin subunit alpha 4 IMP RGD PMID:8550078 RGD:9698438 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO (PMID:19342684) RGD PMID:19342684 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Trim55 tripartite motif-containing 55 acts_upstream_of_or_within_positive_effect ISO MGI:3773035 (MGI:6193412|PMID:26452100) RGD PMID:26452100 MGI:6193412 NCBI chr 2:104,416,972...104,459,117
Ensembl chr 2:104,416,972...104,459,107
JBrowse link
helper T cell diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crk CRK proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:104686 (MGI:5634599|PMID:25621495) RGD PMID:25621495 MGI:5634599 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:88508 (MGI:5634599|PMID:25621495) RGD PMID:25621495 MGI:5634599 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
T-helper 1 cell diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IDA PMID:10477596 BHF-UCL PMID:10477596 RGD:8553666 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    immune system process 2886
      leukocyte migration 386
        diapedesis 8
          helper T cell diapedesis + 3
Path 2
Term Annotations click to browse term
  biological_process 19612
    localization 6449
      localization of cell 1755
        cell motility 1755
          cell migration 1573
            leukocyte migration 386
              cellular extravasation 77
                diapedesis 8
                  helper T cell diapedesis + 3
paths to the root