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ONTOLOGY REPORT - ANNOTATIONS

Term:diapedesis
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Accession:GO:0050904 term browser browse the term
Definition:The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
Comment:Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic.


show annotations for term's descendants           Sort by:
diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd99l2 CD99 molecule-like 2 acts_upstream_of_or_within ISO (PMID:23293350) RGD PMID:23293350
G Fer FER tyrosine kinase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16009680)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16009680 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Itga4 integrin subunit alpha 4 IMP RGD PMID:8550078 RGD:9698438 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO
IEA 		(PMID:19342684)
GO_REF:0000107 		RGD
Ensembl		 PMID:19342684 GO_REF:0000107 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Trim55 tripartite motif-containing 55 acts_upstream_of_or_within_positive_effect ISO
IEA 		MGI:3773035 (PMID:26452100)
GO_REF:0000107 		RGD
Ensembl		 PMID:26452100 GO_REF:0000107 NCBI chr 2:104,016,361...104,058,302
Ensembl chr 2:102,088,443...102,142,168 		JBrowse link
helper T cell diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crk CRK proto-oncogene, adaptor protein acts_upstream_of_or_within ISO
IEA 		MGI:104686 (PMID:25621495)
GO_REF:0000107 		RGD
Ensembl		 PMID:25621495 GO_REF:0000107 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:88508 (PMID:25621495) RGD PMID:25621495 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
T-helper 1 cell diapedesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IDA PMID:10477596 BHF-UCL PMID:10477596 RGD:8553666 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3133
      leukocyte migration 408
        diapedesis 8
          helper T cell diapedesis + 3
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cell motility 2027
        cell migration 1744
          leukocyte migration 408
            cellular extravasation 79
              diapedesis 8
                helper T cell diapedesis + 3
paths to the root