regulation of body fluid levels - Ontology Report

(MGI:1859095|PMID:10839360)

PMID:10839360

MGI:1859095

NCBI chr 2:76,427,112...76,551,494
Ensembl chr 2:76,428,203...76,612,786

HEG1

heart development protein with EGF like domains 1

involved_in

(MGI:3837878|PMID:19151727)

PMID:19151727

GO_REF:0000107 MGI:3837878

NCBI chr33:27,982,127...28,044,379
Ensembl chr33:27,987,252...28,044,363

PDSS2

decaprenyl diphosphate synthase subunit 2

involved_in

(MGI:53710|PMID:5098070)

PMID:5098070

GO_REF:0000107 MGI:53710

NCBI chr12:64,371,548...64,620,652
Ensembl chr12:64,338,950...64,620,367

SCNN1A

sodium channel epithelial 1 subunit alpha

NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980

activation of blood coagulation via clotting cascade

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANO6

anoctamin 6

involved_in

GO_REF:0000107

NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934

blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANO2

anoctamin 2

involved_in

GO_REF:0000043

NCBI chr27:38,976,761...39,320,764
Ensembl chr27:38,833,837...39,320,142

ANO6

anoctamin 6

involved_in

(MGI:5440105|PMID:23021219)

InterPro
UniProt

PMID:23021219

GO_REF:0000002 MGI:5440105

NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934

AP3B1

adaptor related protein complex 3 subunit beta 1

(MGI:55798|PMID:6696991)

MGI:55798

NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258

apolipoprotein H

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

BLOC1S3

biogenesis of lysosomal organelles complex 1 subunit 3

(MGI:3522060|PMID:15265785)

PMID:15265785

MGI:3522060

NCBI chr 1:110,325,351...110,328,226
Ensembl chr 1:110,326,843...110,327,442

BLOC1S6

biogenesis of lysosomal organelles complex 1 subunit 6

involved_in

(MGI:55798|PMID:6696991)

GO_REF:0000107 MGI:55798

NCBI chr30:11,861,119...11,949,451
Ensembl chr30:11,811,339...11,937,353

complement C3

NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761

complement C9

NCBI chr 4:69,660,861...69,719,793
Ensembl chr 4:69,660,907...69,719,562

COMP

cartilage oligomeric matrix protein

(MGI:5694900|PMID:26045608)

PMID:26045608

MGI:5694900

NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625

DTNBP1

dystrobrevin binding protein 1

(MGI:50482|PMID:1936982)

PMID:1936982

MGI:50482

NCBI chr35:14,738,025...14,862,609
Ensembl chr35:14,738,029...14,864,169

ENPP4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

GO_REF:0000043

NCBI chr12:14,353,355...14,366,506
Ensembl chr12:14,353,282...14,365,952

F10

coagulation factor X

involved_in

PMID:10048754 PMID:21873635

(PMID:21873635)

GO_Central
RGD
UniProt

GO_REF:0000043 RGD:2290183

NCBI chr22:60,585,563...60,597,027
Ensembl chr22:60,571,822...60,597,024

F11

coagulation factor XI

involved_in

Ensembl
RGD
UniProt

PMID:10048754

GO_REF:0000043 GO_REF:0000107 RGD:2290183

NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292

F12

coagulation factor XII

involved_in

PMID:10048754 PMID:15351846 PMID:21873635

(PMID:21873635)
(MGI:3720875|PMID:15351846)

GO_Central
MGI
RGD

MGI:3720875 RGD:2290183

NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025

F13A1

coagulation factor XIII A chain

PMID:420942 PMID:12529747

(MGI:2684288|PMID:12529747)

RGD
MGI

MGI:2684288 RGD:1582287

NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773

F13B

coagulation factor XIII B chain

(MGI:5645809|PMID:18224415)

PMID:18224415

MGI:5645809

NCBI chr 7:5,674,458...5,700,928
Ensembl chr 7:5,674,416...5,700,905

coagulation factor II, thrombin

involved_in

UniProt
RGD

PMID:10048754

GO_REF:0000043 RGD:2290183

NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000002

NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180

F2RL2

coagulation factor II thrombin receptor like 2

involved_in

GO_REF:0000002

NCBI chr 3:29,967,278...29,974,316
Ensembl chr 3:29,967,312...29,972,872

F2RL3

F2R like thrombin or trypsin receptor 3

involved_in

GO_REF:0000002

NCBI chr20:45,738,587...45,740,564
Ensembl chr20:45,738,587...45,740,473

coagulation factor III, tissue factor

involved_in

PMID:8900278 PMID:10048754 PMID:12816857 PMID:12855561 PMID:21873635

UniProt
Ensembl

GO_REF:0000043 GO_REF:0000107

NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607

coagulation factor V

involved_in

IEA
ISO
IBA

(MGI:2678846|PMID:12816857), (MGI:2678880|PMID:12855561)
(MGI:83870|PMID:8900278)
(PMID:21873635)

InterPro
MGI
RGD
GO_Central

GO_REF:0000002 MGI:2678846 MGI:2678880 MGI:83870 RGD:2290183

NCBI chr 7:28,999,481...29,069,603
Ensembl chr 7:28,999,512...29,069,296

coagulation factor VII

involved_in

PMID:9384381 PMID:10048754 PMID:21873635

(PMID:21873635)
(MGI:1099680|PMID:9384381)

GO_Central
MGI
RGD
UniProt

GO_REF:0000043 MGI:1099680 RGD:2290183

NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024

coagulation factor VIII

involved_in

PMID:10048754 PMID:15178576 PMID:21873635

UniProt
RGD

PMID:10048754

GO_REF:0000043 RGD:2290183

NCBI chr X:122,894,974...123,046,343
Ensembl chr X:122,885,162...123,043,414

coagulation factor IX

involved_in

IEA
ISO
ISS
IBA

(MGI:3055261|PMID:15178576)
(PMID:21873635)

Ensembl
RGD
MGI
UniProt
GO_Central

GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 MGI:3055261 RGD:2290183

NCBI chr X:109,501,341...109,533,798
Ensembl chr X:109,501,341...109,533,798

fibrinogen alpha chain

involved_in

(MGI:1861538|PMID:10930441)

UniProt
MGI

PMID:10930441

GO_REF:0000043 MGI:1861538

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

fibrinogen beta chain

involved_in

GO_REF:0000043

NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250

GAS6

growth arrest specific 6

involved_in

(MGI:3044336|PMID:15184064)

PMID:15184064

GO_REF:0000107 MGI:3044336

NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875

glycoprotein Ib platelet subunit alpha

involved_in

(MGI:4888094|PMID:20650879), (MGI:4888158|PMID:21037087)

PMID:20650879 PMID:21037087

GO_REF:0000107 MGI:4888094 MGI:4888158

NCBI chr 5:31,681,605...31,683,261

HABP2

hyaluronan binding protein 2

involved_in

(PMID:21873635)

NCBI chr28:24,489,665...24,522,336
Ensembl chr28:24,489,773...24,522,263

HGFAC

HGF activator

involved_in

(PMID:21873635)

NCBI chr 3:60,906,839...60,916,879
Ensembl chr 3:60,906,844...60,915,280

HNF4A

hepatocyte nuclear factor 4 alpha

involved_in

GO_REF:0000107

NCBI chr24:31,847,864...31,908,337
Ensembl chr24:31,847,961...31,905,916

HPS1

HPS1 biogenesis of lysosomal organelles complex 3 subunit 1

(MGI:55798|PMID:6696991)

MGI:55798

NCBI chr28:11,547,457...11,572,248
Ensembl chr28:11,547,741...11,571,613

HPS4

HPS4 biogenesis of lysosomal organelles complex 3 subunit 2

involved_in

(MGI:55798|PMID:6696991)

GO_REF:0000107 MGI:55798

NCBI chr26:20,131,658...20,157,532
Ensembl chr26:19,933,281...20,157,058

HPS5

HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

involved_in

(MGI:55798|PMID:6696991)

GO_REF:0000107 MGI:55798

NCBI chr21:40,725,089...40,770,665
Ensembl chr21:40,726,274...40,770,112

HPS6

HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

involved_in

(MGI:55798|PMID:6696991)

GO_REF:0000107 MGI:55798

NCBI chr28:14,614,434...14,617,138
Ensembl chr28:14,614,584...14,653,629

IFNAR2

interferon alpha and beta receptor subunit 2

involved_in

GO_REF:0000043

NCBI chr31:27,860,094...27,891,361

IL10RB

interleukin 10 receptor subunit beta

involved_in

GO_REF:0000043

NCBI chr31:28,791,541...28,815,163
Ensembl chr31:27,892,394...27,915,637

KLKB1

kallikrein B1

involved_in

GO_REF:0000043

NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292

LNPK

lunapark, ER junction formation factor

involved_in

(MGI:79294|PMID:8835524)

PMID:8835524

GO_REF:0000107 MGI:79294

NCBI chr36:19,731,523...19,809,349
Ensembl chr36:19,732,276...19,808,769

LYST

lysosomal trafficking regulator

(MGI:55798|PMID:6696991)

MGI:55798

NCBI chr 4:4,106,869...4,296,042
Ensembl chr 4:4,089,837...4,294,593

MPIG6B

megakaryocyte and platelet inhibitory receptor G6b

involved_in

(PMID:21873635)
(MGI:5512895|PMID:23112346)

PMID:21873635 PMID:23112346

MGI:5512895

NCBI chr12:1,202,297...1,205,867
Ensembl chr12:1,202,721...1,204,655

NBEAL2

neurobeachin like 2

(MGI:5514081|PMID:23863626)

PMID:23863626

MGI:5514081

NCBI chr20:41,806,903...41,836,286
Ensembl chr20:41,803,702...41,827,587

P2RY8

P2Y receptor family member 8

involved_in

GO_REF:0000002

NCBI chr X:1,060,204...1,097,471

PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

involved_in

(MGI:79294|PMID:8835524)

PMID:8835524

GO_REF:0000107 MGI:79294

NCBI chr26:37,725,205...37,745,103
Ensembl chr26:37,725,616...37,743,928

plasminogen

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260

PROC

protein C, inactivator of coagulation factors Va and VIIIa

involved_in

GO_REF:0000043

NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563

PRSS56

serine protease 56

involved_in

(PMID:21873635)

NCBI chr25:44,157,247...44,165,625
Ensembl chr25:44,160,615...44,165,625

PTPRJ

protein tyrosine phosphatase receptor type J

(MGI:3847185|PMID:19246339)

PMID:19246339

MGI:3847185

NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308

RAB27A

RAB27A, member RAS oncogene family

involved_in

(MGI:1860659|PMID:10859366)

PMID:10859366

GO_REF:0000107 MGI:1860659

NCBI chr30:20,633,576...20,706,240
Ensembl chr30:20,635,400...20,690,521

SERPINC1

serpin family C member 1

involved_in

GO_REF:0000043

NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987

SERPIND1

serpin family D member 1

involved_in

GO_REF:0000002

NCBI chr26:30,686,074...30,697,437
Ensembl chr26:30,686,663...30,693,848

serpin family E member 2

(MGI:4418017|PMID:19855083)

PMID:19855083

MGI:4418017

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

SHH

sonic hedgehog signaling molecule

involved_in

(MGI:79294|PMID:8835524)

PMID:8835524

GO_REF:0000107 MGI:79294

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

SLC4A1

solute carrier family 4 member 1

involved_in

(MGI:3619187|PMID:9716609)

PMID:9716609

GO_REF:0000107 MGI:3619187

NCBI chr 9:19,142,884...19,159,449
Ensembl chr 9:19,146,480...19,157,915

TFPI2

tissue factor pathway inhibitor 2

involved_in

GO_REF:0000104

NCBI chr14:19,399,259...19,403,890
Ensembl chr14:19,399,720...19,403,708

THBD

thrombomodulin

involved_in

GO_REF:0000043

NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649

TSPAN32

tetraspanin 32

(MGI:3804129|PMID:16720835)

PMID:16720835

MGI:3804129

NCBI chr18:46,422,499...46,438,512
Ensembl chr18:46,422,259...46,437,272

VKORC1

vitamin K epoxide reductase complex subunit 1

involved_in

(PMID:21873635)
(MGI:5559848|PMID:19492146)

PMID:19492146 PMID:21873635

MGI:5559848

NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547

VWF

von Willebrand factor

involved_in

IBA
ISO
IEA
ISS

(PMID:21873635)
(MGI:1276653|PMID:9689113), (MGI:3709713|PMID:17380206), (MGI:4888158|PMID:21037087)

GO_Central
RGD
MGI
UniProt

PMID:9504130 PMID:9689113 PMID:10709908 PMID:17380206 PMID:21037087 PMID:21873635

GO_REF:0000024 GO_REF:0000043 MGI:1276653 MGI:3709713 MGI:4888158 RGD:1599012 RGD:1599016

NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142

blood coagulation, common pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fibrinogen alpha chain

involved_in

InterPro
MGI
GO_Central
Ensembl

GO_REF:0000107

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

blood coagulation, fibrin clot formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F13A1

coagulation factor XIII A chain

involved_in

IEA
ISO
IBA

(MGI:5645809|PMID:18224415)
(PMID:21873635)

PMID:18224415 PMID:21873635

GO_REF:0000002 GO_REF:0000107 MGI:5645809

NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773

FBLN1

fibulin 1

involved_in

(PMID:7642629)

PMID:7642629

NCBI chr10:20,498,097...20,564,776
Ensembl chr10:20,498,567...20,627,836

fibrinogen alpha chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250

fibrinogen gamma chain

involved_in

(PMID:11001902)
(PMID:16846481)

PMID:11001902 PMID:16846481

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

blood coagulation, intrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

GO_REF:0000107

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

coagulation factor VIII

involved_in

PMID:2513867 PMID:21873635

(PMID:21873635)

GO_Central
RGD

RGD:1582368

NCBI chr X:122,894,974...123,046,343
Ensembl chr X:122,885,162...123,043,414

body fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A2

NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281

EDN1

endothelin 1

involved_in

(MGI:3051206|PMID:15314687)

PMID:15314687

GO_REF:0000107 MGI:3051206

NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383

GUCA2B

guanylate cyclase activator 2B

involved_in

(MGI:2678878|PMID:14561709)

PMID:14561709

GO_REF:0000107 MGI:2678878

NCBI chr15:1,094,283...1,096,605
Ensembl chr15:1,094,276...1,096,688

RAB14

RAB14, member RAS oncogene family

NCBI chr11:74,157,497...74,172,817
Ensembl chr11:74,159,414...74,172,810

TSC22D3

TSC22 domain family member 3

NCBI chr X:81,235,489...81,298,290
Ensembl chr X:81,235,809...81,298,192

cerebrospinal fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

(PMID:16814974)

PMID:16814974

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AQP4

aquaporin 4

(MGI:6277731|PMID:30293570)

CACAO

PMID:30293570

MGI:6277731

NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089

CELSR2

cadherin EGF LAG seven-pass G-type receptor 2

involved_in

(MGI:4460066|PMID:20473291)

PMID:20473291

GO_REF:0000107 MGI:4460066

NCBI chr 6:42,547,638...42,573,407
Ensembl chr 6:42,548,983...42,573,962

SLC4A5

solute carrier family 4 member 5

involved_in

(MGI:5292606|PMID:21705333)

PMID:21705333

GO_REF:0000107 MGI:5292606

NCBI chr17:48,769,963...48,882,201
Ensembl chr17:48,797,807...48,880,441

TP73

tumor protein p73

(MGI:1354064|PMID:10716451)

PMID:10716451

MGI:1354064

NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839

establishment of skin barrier

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCA12

ATP binding cassette subfamily A member 12

involved_in

(MGI:3829841|PMID:18957418)
(MGI:4460077|PMID:18802465)
(MGI:3807143|PMID:18632686)

PMID:18632686 PMID:18802465 PMID:18957418

GO_REF:0000107 MGI:3807143 MGI:3829841 MGI:4460077

NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736

ALOX12

arachidonate 12-lipoxygenase, 12S type

involved_in

(MGI:1339275|PMID:10383730)

PMID:10383730

GO_REF:0000107 MGI:1339275

NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119

ALOX12B

arachidonate 12-lipoxygenase, 12R type

involved_in

(MGI:3789553|PMID:17403930), (MGI:5141179|PMID:21558561)

PMID:17403930 PMID:21558561

GO_REF:0000107 MGI:3789553 MGI:5141179

NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552

ALOXE3

arachidonate lipoxygenase 3

involved_in

(MGI:5488571|PMID:22832496)

PMID:22832496

GO_REF:0000107 MGI:5488571

NCBI chr 5:32,917,681...32,941,470
Ensembl chr 5:32,918,065...32,941,752

CLDN1

claudin 1

involved_in

(MGI:2176640|PMID:11889141)

PMID:11889141

GO_REF:0000107 MGI:2176640

NCBI chr34:22,303,058...22,319,101
Ensembl chr34:22,303,850...22,319,033

CLDN4

claudin 4

involved_in

GO_REF:0000107

NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145

CYP26B1

cytochrome P450 family 26 subfamily B member 1

involved_in

(MGI:5466369|PMID:22366455)

PMID:22366455

GO_REF:0000107 MGI:5466369

NCBI chr17:50,633,397...50,653,882
Ensembl chr17:50,633,413...50,653,894

ELOVL1

ELOVL fatty acid elongase 1

involved_in

(MGI:5532629|PMID:23689133)

PMID:23689133

GO_REF:0000107 MGI:5532629

NCBI chr15:16,798,305...16,803,071
Ensembl chr15:16,798,370...16,802,899

FA2H

fatty acid 2-hydroxylase

involved_in

GO_REF:0000107

NCBI chr 5:75,878,539...75,923,886
Ensembl chr 5:75,878,243...75,948,094

FLG

filaggrin

involved_in

PMID:22366455 PMID:23403047

(MGI:5466369|PMID:22366455)
(PMID:23403047)

MGI
UniProt

MGI:5466369

NCBI chr17:61,217,915...61,233,068

GAK

cyclin G associated kinase

(MGI:5305417|PMID:18434600)

PMID:18434600

MGI:5305417

NCBI chr 3:91,575,537...91,630,715
Ensembl chr 3:91,574,751...91,630,663

GRHL1

grainyhead like transcription factor 1

involved_in

(MGI:5585711|PMID:24586629)

PMID:24586629

GO_REF:0000107 MGI:5585711

NCBI chr17:6,953,945...7,007,175
Ensembl chr17:6,953,836...7,006,134

GRHL3

grainyhead like transcription factor 3

involved_in

(MGI:5617425|PMID:25347468)

PMID:25347468

GO_REF:0000107 MGI:5617425

NCBI chr 2:75,290,594...75,324,593
Ensembl chr 2:75,290,596...75,324,496

KDF1

keratinocyte differentiation factor 1

involved_in

(MGI:5529391|PMID:24075906)

PMID:24075906

GO_REF:0000107 MGI:5529391

NCBI chr 2:73,198,278...73,206,691
Ensembl chr 2:73,197,580...73,207,153

KRT1

keratin 1

(MGI:5507924|PMID:23132931)

PMID:23132931

MGI:5507924

NCBI chr27:2,422,150...2,427,160

LOC483211

filaggrin-2

involved_in

(PMID:23403047)

PMID:23403047

NCBI chr17:61,311,558...61,323,059

LSR

lipolysis stimulated lipoprotein receptor

involved_in

(MGI:6316553|PMID:21245199)

Ensembl
ARUK-UCL

PMID:21245199

GO_REF:0000107 MGI:6316553

NCBI chr 1:117,319,672...117,333,426
Ensembl chr 1:117,319,658...117,333,419

MET

MET proto-oncogene, receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027

PNPLA1

patatin like phospholipase domain containing 1

involved_in

(MGI:5882269|PMID:27751867), (MGI:5888934|PMID:28248300)

PMID:27751867 PMID:28248300

GO_REF:0000107 MGI:5882269 MGI:5888934

NCBI chr12:5,377,430...5,423,556
Ensembl chr12:5,377,430...5,423,556

SFN

stratifin

involved_in

(MGI:5529391|PMID:24075906)

PMID:24075906

GO_REF:0000107 MGI:5529391

NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537

STARD7

StAR related lipid transfer domain containing 7

(MGI:5906122|PMID:25980009)

PMID:25980009

MGI:5906122

NCBI chr17:34,534,036...34,562,733
Ensembl chr17:34,534,529...34,554,994

STMN1

stathmin 1

involved_in

GO_REF:0000107

NCBI chr 2:74,035,462...74,043,352
Ensembl chr 2:74,035,457...74,043,349

TMEM79

transmembrane protein 79

involved_in

PMID:24060273 PMID:24084074

(MGI:5518480|PMID:24060273)
(MGI:5519142|PMID:24084074)

Ensembl
UniProt
MGI

GO_REF:0000107 MGI:5518480 MGI:5519142

NCBI chr 7:41,591,332...41,597,993
Ensembl chr 7:41,591,848...41,595,816

TMPRSS13

transmembrane serine protease 13

(MGI:5604957|PMID:24832573)

PMID:24832573

MGI:5604957

NCBI chr 5:15,726,007...15,754,767
Ensembl chr 5:15,700,458...15,753,543

TP63

tumor protein p63

involved_in

(MGI:5529391|PMID:24075906)

PMID:24075906

GO_REF:0000107 MGI:5529391

NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046

UGCG

UDP-glucose ceramide glucosyltransferase

involved_in

(MGI:3706199|PMID:17145749)

PMID:17145749

GO_REF:0000107 MGI:3706199

NCBI chr11:66,439,346...66,472,897
Ensembl chr11:66,439,346...66,472,897

fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA2

annexin A2

(MGI:3027337|PMID:14702107)

PMID:11848438 PMID:21873635

PMID:14702107

MGI:3027337

NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281

CPB2

carboxypeptidase B2

involved_in

IEA
ISO
IBA

(PMID:21873635)

InterPro
RGD
GO_Central

GO_REF:0000002 RGD:632532

NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170

coagulation factor II, thrombin

involved_in

GO_REF:0000107

NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459

fibrinogen alpha chain

involved_in

GO_REF:0000107

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250

fibrinogen gamma chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

NCBI chr 5:31,681,605...31,683,261

PLAU

plasminogen activator, urokinase

involved_in

(PMID:21873635)
(MGI:1277054|PMID:9733098)

PMID:9733098 PMID:21873635

MGI:1277054

NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851

plasminogen

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260

PROS1

protein S

involved_in

GO_REF:0000043

NCBI chr33:1,628,074...1,691,441
Ensembl chr33:1,628,105...1,692,058

hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA7

annexin A7

(MGI:3046086|PMID:12925238)

PMID:12925238

MGI:3046086

NCBI chr 4:23,933,959...23,961,968
Ensembl chr 4:23,934,234...23,961,880

glycoprotein Ib platelet subunit alpha

(MGI:1860858|PMID:10706630)

PMID:10706630

MGI:1860858

NCBI chr 5:31,681,605...31,683,261

TSPAN32

tetraspanin 32

(MGI:3804129|PMID:16720835)

PMID:16720835

MGI:3804129

NCBI chr18:46,422,499...46,438,512
Ensembl chr18:46,422,259...46,437,272

VWF

von Willebrand factor

involved_in

(MGI:1276653|PMID:9689113)

UniProt
MGI

PMID:9689113

GO_REF:0000024 MGI:1276653

NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142

ZNF385A

zinc finger protein 385A

involved_in

(MGI:3505817|PMID:11927637)

PMID:11927637

GO_REF:0000107 MGI:3505817

NCBI chr27:928,250...948,275
Ensembl chr27:928,349...947,186

lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB1

ATP binding cassette subfamily B member 1

NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727

ALAS2

5'-aminolevulinate synthase 2

NCBI chr X:46,703,477...46,731,767
Ensembl chr X:46,703,477...46,723,529

APRT

adenine phosphoribosyltransferase

NCBI chr 5:64,563,154...64,565,537
Ensembl chr 5:64,563,192...64,565,445

ATP2B2

ATPase plasma membrane Ca2+ transporting 2

(MGI:3510467|PMID:15302868)

PMID:15302868

MGI:3510467

NCBI chr20:7,665,468...8,037,407
Ensembl chr20:7,749,807...8,034,474

ATP7A

ATPase copper transporting alpha

NCBI chr X:60,203,336...60,356,525
Ensembl chr X:60,203,270...60,352,869

ATP7B

ATPase copper transporting beta

PMID:1588441 PMID:6863890 PMID:16741141 PMID:28089327

(MGI:49578|PMID:1588441), (MGI:55573|PMID:6863890)

MGI
RGD

MGI:49578 MGI:55573 MGI:71982 RGD:1599391 RGD:25671605

NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266

BCAT2

branched chain amino acid transaminase 2

PMID:11171603 PMID:11787736

RGD

RGD:1599445 RGD:62398

NCBI chr 1:107,539,125...107,549,286
Ensembl chr 1:107,538,465...107,549,234

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chr17:21,198,839...21,221,897
Ensembl chr17:21,197,826...21,221,635

CAV1

caveolin 1

involved_in

(MGI:3703676|PMID:12388746)

PMID:12388746

GO_REF:0000107 MGI:3703676

NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935

CCND1

cyclin D1

involved_in

(MGI:1342136|PMID:10419681)
(MGI:3045614|PMID:11747812)

PMID:10419681 PMID:11747812

GO_REF:0000107 MGI:1342136 MGI:3045614

NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005

CDO1

cysteine dioxygenase type 1

NCBI chr11:5,512,996...5,524,556
Ensembl chr11:5,371,378...5,524,562

CHUK

component of inhibitor of nuclear factor kappa B kinase complex

(MGI:3045614|PMID:11747812)

PMID:11747812

MGI:3045614

NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512

ceruloplasmin

NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369

CREB1

cAMP responsive element binding protein 1

involved_in

(MGI:3611103|PMID:16141355)

PMID:16141355

GO_REF:0000107 MGI:3611103

NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556

CSN2

casein beta

involved_in

GO_REF:0000107

NCBI chr13:59,436,726...59,444,398
Ensembl chr13:59,438,601...59,444,398

CSN3

casein kappa

involved_in

(PMID:21873635)
(MGI:3639646|PMID:16698927)

PMID:16698927 PMID:21873635

MGI:3639646

NCBI chr13:59,613,026...59,629,095
Ensembl chr13:59,621,106...59,626,552

CYP27B1

cytochrome P450 family 27 subfamily B member 1

NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911

DHODH

dihydroorotate dehydrogenase (quinone)

NCBI chr 5:77,756,411...77,766,207
Ensembl chr 5:77,756,407...77,774,090

EIF2AK3

eukaryotic translation initiation factor 2 alpha kinase 3

(MGI:3815371|PMID:18852460)

PMID:18852460

MGI:3815371

NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812

ERBB4

erb-b2 receptor tyrosine kinase 4

involved_in

(MGI:5297795|PMID:10508857)

PMID:10508857

GO_REF:0000107 MGI:5297795

NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426

FOXB1

forkhead box B1

involved_in

(MGI:1931655|PMID:11170346)

PMID:11170346

GO_REF:0000107 MGI:1931655

NCBI chr30:24,822,137...24,825,833
Ensembl chr30:24,823,815...24,824,792

GC vitamin D binding protein

NCBI chr13:60,795,305...60,828,038
Ensembl chr13:60,795,305...60,827,929

GHRHR

growth hormone releasing hormone receptor

involved_in

(MGI:49336|PMID:2980124), (MGI:54124|PMID:1270792)

PMID:1270792 PMID:2980124

GO_REF:0000107 MGI:49336 MGI:54124

NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753

GOT2

glutamic-oxaloacetic transaminase 2

NCBI chr 2:57,968,833...57,994,219
Ensembl chr 2:57,968,833...57,994,218

GPAT4

glycerol-3-phosphate acyltransferase 4

involved_in

(MGI:3623167|PMID:16449762)

PMID:16449762

GO_REF:0000107 MGI:3623167

NCBI chr16:23,990,142...24,022,822
Ensembl chr16:23,911,972...24,010,152

HIF1A

hypoxia inducible factor 1 subunit alpha

involved_in

(MGI:2654263|PMID:12620994)

PMID:12620994

GO_REF:0000107 MGI:2654263

NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692

hexokinase 2

NCBI chr17:48,287,367...48,329,470
Ensembl chr17:48,289,272...48,348,663

KALRN

kalirin RhoGEF kinase

involved_in

(MGI:5551307|PMID:23116210)

PMID:23116210

GO_REF:0000107 MGI:5551307

NCBI chr33:27,161,403...27,752,891
Ensembl chr33:27,161,504...27,746,497

MED1

mediator complex subunit 1

involved_in

(MGI:3576991|PMID:15647257)

PMID:15647257

GO_REF:0000107 MGI:3576991

NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349

MET

MET proto-oncogene, receptor tyrosine kinase

NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027

MT-CO2

mitochondrially encoded cytochrome c oxidase II

NCBI chr MT:7,034...7,717
Ensembl chr MT:7,034...7,717

metaxin 1

NCBI chr 7:42,322,755...42,327,918
Ensembl chr 7:42,322,762...42,328,701

MUC4

mucin 4, cell surface associated

NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802

NCOA1

nuclear receptor coactivator 1

NCBI chr17:18,880,676...19,124,300
Ensembl chr17:18,880,383...19,122,258

NCOR1

nuclear receptor corepressor 1

NCBI chr 5:39,687,530...39,837,003
Ensembl chr 5:39,687,543...39,836,464

NCOR2

nuclear receptor corepressor 2

NCBI chr26:5,352,670...5,493,741
Ensembl chr26:5,331,459...5,493,830

NEURL1

neuralized E3 ubiquitin protein ligase 1

involved_in

(MGI:2151733|PMID:11585928)

PMID:11585928

GO_REF:0000107 MGI:2151733

NCBI chr28:15,856,494...15,935,897
Ensembl chr28:15,856,616...15,933,763

NME1

non-metastatic cells 1, protein (NM23A) expressed in

(MGI:3626054|PMID:12848338)

PMID:12848338

MGI:3626054

NCBI chr 9:26,990,336...26,998,895
Ensembl chr 9:26,990,469...26,998,955

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr 3:8,141,508...8,312,081
Ensembl chr 3:8,142,061...8,290,477

PMCH

pro-melanin concentrating hormone

NCBI chr15:41,036,428...41,037,571
Ensembl chr15:41,036,428...41,037,553

PPAT

phosphoribosyl pyrophosphate amidotransferase

NCBI chr13:48,618,460...48,656,164
Ensembl chr13:48,620,714...48,655,780

PRLR

prolactin receptor

(MGI:2137168|PMID:11445538)
(MGI:2153620|PMID:11706048), (MGI:3623843|PMID:16469767)

PMID:11445538 PMID:11706048 PMID:16469767

MGI:2137168 MGI:2153620 MGI:3623843

NCBI chr 4:73,147,919...73,280,970
Ensembl chr 4:73,110,858...73,273,916

RPLP0

ribosomal protein lateral stalk subunit P0

NCBI chr26:16,148,463...16,154,048
Ensembl chr26:16,148,460...16,153,614

SERPINC1

serpin family C member 1

NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987

SLC29A1

solute carrier family 29 member 1 (Augustine blood group)

NCBI chr12:12,632,233...12,644,669
Ensembl chr12:12,634,194...12,644,667

SLC29A2

solute carrier family 29 member 2

NCBI chr18:50,946,647...50,955,085
Ensembl chr18:50,946,724...50,954,413

SLC30A4

solute carrier family 30 member 4

NCBI chr30:11,827,719...11,859,413
Ensembl chr30:11,834,678...11,859,311

SLC6A3

solute carrier family 6 member 3

involved_in

(MGI:894559|PMID:9247269)

PMID:9247269

GO_REF:0000107 MGI:894559

NCBI chr34:11,209,118...11,245,456
Ensembl chr34:11,210,939...11,246,742

SOCS2

suppressor of cytokine signaling 2

involved_in

(MGI:2137168|PMID:11445538)

PMID:11445538

GO_REF:0000107 MGI:2137168

NCBI chr15:33,761,434...33,788,973
Ensembl chr15:33,785,545...33,877,869

STAT5A

signal transducer and activator of transcription 5A

PMID:8584036 PMID:9630227 PMID:11706048

(MGI:2153620|PMID:11706048)
(MGI:2181561|PMID:9630227)

RGD
MGI

MGI:2153620 MGI:2181561 RGD:730121

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

STAT5B

signal transducer and activator of transcription 5B

involved_in

(MGI:2153620|PMID:11706048), (MGI:2181561|PMID:9630227)

PMID:9630227 PMID:11706048

GO_REF:0000107 MGI:2153620 MGI:2181561

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

UMPS

uridine monophosphate synthetase

NCBI chr33:27,754,592...27,782,517
Ensembl chr33:27,754,643...27,782,514

UPRT

uracil phosphoribosyltransferase homolog

NCBI chr X:58,570,623...58,576,980
Ensembl chr X:58,543,425...58,575,926

USF2

upstream transcription factor 2, c-fos interacting

involved_in

(MGI:2679398|PMID:12907752)

PMID:12907752

GO_REF:0000107 MGI:2679398

NCBI chr 1:117,308,882...117,319,397
Ensembl chr 1:117,309,222...117,367,616

VDR

vitamin D receptor

involved_in

(MGI:3051725|PMID:15178742)

PMID:15178742

GO_REF:0000107 MGI:3051725

NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470

VEGFA

vascular endothelial growth factor A

(MGI:3789854|PMID:17625068)

PMID:17625068

MGI:3789854

NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965

XDH

xanthine dehydrogenase

involved_in

(MGI:2447927|PMID:12502743)

PMID:12502743

GO_REF:0000107 MGI:2447927

NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935

ZBTB7B

zinc finger and BTB domain containing 7B

involved_in

(MGI:6120228|PMID:29420538)

PMID:29420538

GO_REF:0000107 MGI:6120228

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

milk ejection reflex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GJA1

gap junction protein alpha 1

(MGI:4452310|PMID:20089884)

PMID:20089884

MGI:4452310

NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936

mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGR2

anterior gradient 2, protein disulphide isomerase family member

involved_in

(MGI:3844381|PMID:19359471)

PMID:19359471

GO_REF:0000107 MGI:3844381

NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686

SCNN1B

sodium channel epithelial 1 subunit beta

involved_in

ISO
IEA

(MGI:6478086|PMID:22419116)

MGI
Ensembl

PMID:22419116

GO_REF:0000107 MGI:6478086

NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349

TRAF3IP2

TRAF3 interacting protein 2

involved_in

ISO
IEA

(MGI:3830744|PMID:19155511)

MGI
Ensembl

PMID:19155511

GO_REF:0000107 MGI:3830744

NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518

VAMP2

vesicle associated membrane protein 2

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr 5:32,975,372...32,977,967

VAMP3

vesicle associated membrane protein 3

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr 5:61,430,711...61,440,626
Ensembl chr 5:61,430,740...61,439,063

VAMP8

vesicle associated membrane protein 8

involved_in

(PMID:21873635)
(MGI:5484853|PMID:22144578)

PMID:21873635 PMID:22144578

MGI:5484853

NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739

multicellular organismal water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

(PMID:17645239)

PMID:17645239

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AQP4

aquaporin 4

involved_in

(PMID:16814974), (PMID:17645239)

PMID:16814974 PMID:17645239

NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089

arginine vasopressin

NCBI chr24:18,183,057...18,184,827
Ensembl chr24:18,183,057...18,184,883

BPIFA1

BPI fold containing family A member 1

involved_in

GO_REF:0000107

NCBI chr24:22,475,407...22,482,666
Ensembl chr24:22,457,631...22,482,661

CFTR

CF transmembrane conductance regulator

involved_in

GO_REF:0000024

NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977

EXT1

exostosin glycosyltransferase 1

involved_in

(MGI:6343289|PMID:31365577)

PMID:31365577

GO_REF:0000107 MGI:6343289

NCBI chr13:17,172,497...17,457,084
Ensembl chr13:17,172,705...17,456,469

EXT2

exostosin glycosyltransferase 2

involved_in

(MGI:6343289|PMID:31365577)

PMID:31365577

GO_REF:0000107 MGI:6343289

NCBI chr18:44,987,310...45,122,339
Ensembl chr18:44,987,748...45,129,974

SCNN1A

sodium channel epithelial 1 subunit alpha

involved_in

PMID:17430990 PMID:28567665

GO_REF:0000107

NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980

SCNN1B

sodium channel epithelial 1 subunit beta

involved_in

IEA
ISO
ISS

(MGI:3815289|PMID:17430990), (MGI:6478095|PMID:28567665)

Ensembl
MGI
UniProt

GO_REF:0000024 GO_REF:0000107 MGI:3815289 MGI:6478095

NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349

SCNN1G

sodium channel epithelial 1 subunit gamma

involved_in

GO_REF:0000107

NCBI chr 6:22,566,568...22,593,479
Ensembl chr 6:22,567,711...22,593,503

TRPV4

transient receptor potential cation channel subfamily V member 4

involved_in

PMID:23136043
(PMID:23136043)

PMID:23136043

RGD:10400856

NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165

negative regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADTRP

androgen dependent TFPI regulating protein

involved_in

GO_REF:0000107

NCBI chr35:11,300,186...11,362,893
Ensembl chr35:11,300,887...11,362,101

annexin A5

NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378

APOE

apolipoprotein E

involved_in

(PMID:8995232)

PMID:8995232

NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440

apolipoprotein H

involved_in

GO_REF:0000107

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

CD34

CD34 molecule

involved_in

ISS
IEA

UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:6,734,363...6,747,991
Ensembl chr 7:6,734,363...6,748,581

KNG1

kininogen 1

involved_in

GO_REF:0000107

NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081

PROC

protein C, inactivator of coagulation factors Va and VIIIa

involved_in

PMID:1440533 PMID:9616155 PMID:9788960 PMID:21873635

(PMID:21873635)
(MGI:1306904|PMID:9788960)
(MGI:1261704|PMID:9616155)

GO_Central
RGD
MGI

MGI:1261704 MGI:1306904 RGD:11100042

NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563

serpin family E member 2

involved_in

PMID:17379830

PMID:17379830

GO_REF:0000107 RGD:8553298

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

TFPI

tissue factor pathway inhibitor

involved_in

GO_REF:0000107

NCBI chr36:29,457,131...29,546,455
Ensembl chr36:29,459,371...29,511,310

THBD

thrombomodulin

involved_in

GO_REF:0000002

NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649

tetraspanin 8

NCBI chr10:12,786,824...12,818,257
Ensembl chr10:12,786,867...12,818,088

negative regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

GO_REF:0000107

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

carboxypeptidase B2

NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170

histidine rich glycoprotein

involved_in

(PMID:21873635)
(MGI:3789419|PMID:15869579)

PMID:15869579 PMID:21873635

MGI:3789419

NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537

plasminogen

involved_in

GO_REF:0000107

NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260

SERPINE1

serpin family E member 1

involved_in

GO_REF:0000107

NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301

SERPINF2

serpin family F member 2

involved_in

Ensembl
RGD

PMID:6506034

GO_REF:0000107 RGD:1625541

NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036

THBS1

thrombospondin 1

involved_in

GO_REF:0000107

NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915

negative regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor II thrombin receptor

involved_in

PMID:12644441

PMID:12644441

GO_REF:0000024 RGD:1582293

NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687

GJA5

gap junction protein alpha 5

NCBI chr17:58,289,327...58,305,315
Ensembl chr17:58,289,327...58,305,315

PTPRO

protein tyrosine phosphatase receptor type O

involved_in

PMID:19403647

PMID:19403647

GO_REF:0000024 RGD:8554129

NCBI chr27:31,082,334...31,322,024
Ensembl chr27:31,084,544...31,322,022

urotensin 2

NCBI chr 5:61,503,268...61,508,146

urotensin 2 receptor

negative regulation of glomerular filtration by angiotensin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYBA

cytochrome b-245 alpha chain

NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893

negative regulation of hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COMP

cartilage oligomeric matrix protein

involved_in

(MGI:5694900|PMID:26045608)

PMID:26045608

GO_REF:0000107 MGI:5694900

NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625

negative regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADA

adenosine deaminase

involved_in

(MGI:3051181|PMID:15240734), (MGI:3525377|PMID:15630442)
(MGI:3525377|PMID:15630442)

PMID:15240734 PMID:15630442

GO_REF:0000107 MGI:3051181 MGI:3525377

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

ADORA1

adenosine A1 receptor

involved_in

(MGI:3525377|PMID:15630442)

PMID:15630442

GO_REF:0000107 MGI:3525377

NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051

negative regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MADD

MAP kinase activating death domain

NCBI chr18:42,290,226...42,332,237
Ensembl chr18:42,290,754...42,328,586

negative regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FAM120C

family with sequence similarity 120C

involved_in

GO_REF:0000107

NCBI chr X:45,780,015...45,943,571
Ensembl chr X:45,571,840...46,081,994

NR1H3

nuclear receptor subfamily 1 group H member 3

involved_in

(MGI:3822255|PMID:18806227)

PMID:18806227

GO_REF:0000107 MGI:3822255

NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236

PHF8

PHD finger protein 8

involved_in

GO_REF:0000107

NCBI chr X:45,635,204...45,741,850
Ensembl chr X:45,571,840...46,081,994

STK39

serine/threonine kinase 39

involved_in

(MGI:5002793|PMID:21317537)

GO_REF:0000107 MGI:5002793

NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160

VPS25

vacuolar protein sorting 25 homolog

(MGI:5002793|PMID:21317537)

MGI:5002793

NCBI chr 9:20,242,230...20,247,396

WNK1

WNK lysine deficient protein kinase 1

involved_in

(MGI:5002793|PMID:21317537)

GO_REF:0000107 MGI:5002793

NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806

WNK3

WNK lysine deficient protein kinase 3

involved_in

(MGI:5002793|PMID:21317537)

GO_REF:0000107 MGI:5002793

NCBI chr X:45,951,049...46,111,643
Ensembl chr X:45,571,840...46,081,994

negative regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APOE

apolipoprotein E

involved_in

GO_REF:0000107

NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440

C1QTNF1

C1q and TNF related 1

involved_in

(PMID:16195328)

PMID:16195328

NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053

PDGFA

platelet derived growth factor subunit A

involved_in

(PMID:2538439)

PMID:2538439

NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396

PDGFB

platelet derived growth factor subunit B

involved_in

IEA
ISS

GO_REF:0000024 GO_REF:0000107

NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746

PDGFRA

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000107

NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278

serpin family E member 2

(MGI:4418017|PMID:19855083)

PMID:19855083

MGI:4418017

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

negative regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

NCBI chr 6:33,385,779...33,471,348
Ensembl chr 6:33,376,996...33,471,326

ADAMTS18

ADAM metallopeptidase with thrombospondin type 1 motif 18

involved_in

(MGI:3848389|PMID:19218546)

PMID:19218546

GO_REF:0000107 MGI:3848389

NCBI chr 5:73,769,462...73,907,024
Ensembl chr 5:73,772,114...73,905,264

adrenoceptor beta 2

NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298

ALOX12

arachidonate 12-lipoxygenase, 12S type

involved_in

(MGI:1202206|PMID:9501222)

PMID:9501222

GO_REF:0000107 MGI:1202206

NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119

C1QTNF1

C1q and TNF related 1

involved_in

GO_REF:0000107

NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053

CD9

CD9 molecule

involved_in

(PMID:18541721)

PMID:18541721

NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576

CEACAM1

CEA cell adhesion molecule 1

(MGI:3835235|PMID:19008452)

PMID:19008452

MGI:3835235

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

fibrinogen gamma chain

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

PRKCD

protein kinase C delta

involved_in

ISS
ISO
IEA

(MGI:3813784|PMID:16940418)

UniProt
UniProt
Ensembl

PMID:16940418

GO_REF:0000024 GO_REF:0000107 MGI:3813784

NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191

PRKG1

protein kinase cGMP-dependent 1

involved_in

GO_REF:0000107

NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729

PTGER3

prostaglandin E receptor 3

NCBI chr 6:74,932,789...74,986,573

serpin family E member 2

(MGI:4418017|PMID:19855083)

PMID:19855083

MGI:4418017

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

SH2B3

SH2B adaptor protein 3

involved_in

(MGI:5905608|PMID:27430239)

PMID:27430239

GO_REF:0000107 MGI:5905608

NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204

UBASH3B

ubiquitin associated and SH3 domain containing B

involved_in

(MGI:4838721|PMID:20585042)

PMID:20585042

GO_REF:0000107 MGI:4838721

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

negative regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NEUROG1

neurogenin 1

involved_in

GO_REF:0000107

NCBI chr11:23,563,128...23,564,819
Ensembl chr11:23,563,803...23,564,543

TIFAB

TIFA inhibitor

involved_in

GO_REF:0000107

NCBI chr11:23,492,317...23,495,825
Ensembl chr11:23,492,867...23,493,352

negative regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

(MGI:4457984|PMID:20466003)

PMID:20466003

GO_REF:0000024 MGI:4457984

NCBI chr27:5,739,514...5,752,888
Ensembl chr27:5,733,586...5,752,888

adrenoceptor beta 1

NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684

adrenoceptor beta 2

NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298

AVPR2

arginine vasopressin receptor 2

NCBI chr X:121,751,606...121,754,771
Ensembl chr X:121,752,027...121,754,771

MLLT6

MLLT6, PHD finger containing

involved_in

(MGI:5644399|PMID:21546577)

PMID:21546577

GO_REF:0000107 MGI:5644399

NCBI chr 9:23,504,750...23,526,747
Ensembl chr 9:23,506,959...23,526,690

OXT

oxytocin/neurophysin I prepropeptide

NCBI chr24:18,193,381...18,194,232
Ensembl chr24:18,193,339...18,194,170

SLC4A1

solute carrier family 4 member 1

involved_in

(MGI:3843596|PMID:17409310)

PMID:17409310

GO_REF:0000107 MGI:3843596

NCBI chr 9:19,142,884...19,159,449
Ensembl chr 9:19,146,480...19,157,915

SLC5A2

solute carrier family 5 member 2

NCBI chr 6:16,765,935...16,772,145
Ensembl chr 6:16,765,938...16,772,137

urotensin 2

NCBI chr 5:61,503,268...61,508,146

urotensin 2 receptor

pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

(PMID:12801959)

PMID:12801959

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AQP5

aquaporin 5

involved_in

GO_REF:0000107

NCBI chr27:4,735,313...4,742,975
Ensembl chr27:4,735,538...4,737,650

CCKAR

cholecystokinin A receptor

NCBI chr 3:84,010,700...84,019,066
Ensembl chr 3:84,010,205...84,021,293

CEL

carboxyl ester lipase

involved_in

GO_REF:0000107

NCBI chr 9:51,337,205...51,345,284
Ensembl chr 9:51,337,187...51,362,422

COPA

COPI coat complex subunit alpha

involved_in

GO_REF:0000107

NCBI chr38:21,892,995...21,936,076
Ensembl chr38:21,892,993...21,936,458

DBI

diazepam binding inhibitor, acyl-CoA binding protein

NCBI chr19:30,640,429...30,645,704
Ensembl chr19:30,640,429...30,646,405

GTF3C5

general transcription factor IIIC subunit 5

involved_in

GO_REF:0000107

NCBI chr 9:51,347,273...51,362,621
Ensembl chr 9:51,337,187...51,362,422

NPR3

natriuretic peptide receptor 3

NCBI chr 4:74,794,553...74,863,344
Ensembl chr 4:74,799,857...74,862,969

urocortin

NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312

phosphatidylserine exposure on blood platelet

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANO6

anoctamin 6

involved_in

GO_REF:0000107

NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934

platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN1

actinin alpha 1

NOT|involved_in

(PMID:24069336)

PMID:24069336

NCBI chr 8:42,714,806...42,808,318
Ensembl chr 8:42,712,142...42,808,323

ADRA2A

adrenoceptor alpha 2A

involved_in

GO_REF:0000002

NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684

ADRA2B

adrenoceptor alpha 2B

involved_in

GO_REF:0000002

NCBI chr17:34,615,121...34,618,480
Ensembl chr17:34,615,096...34,656,791

ADRA2C

adrenoceptor alpha 2C

involved_in

GO_REF:0000002

NCBI chr 3:60,608,632...60,648,112
Ensembl chr 3:60,646,132...60,647,722

ANO2

anoctamin 2

involved_in

GO_REF:0000107

NCBI chr27:38,976,761...39,320,764
Ensembl chr27:38,833,837...39,320,142

AXL

AXL receptor tyrosine kinase

involved_in

(PMID:21873635)
(MGI:3528131|PMID:15650770)

PMID:15650770 PMID:21873635

MGI:3528131

NCBI chr 1:112,699,679...112,727,434
Ensembl chr 1:112,700,365...112,726,960

BLOC1S3

biogenesis of lysosomal organelles complex 1 subunit 3

involved_in

GO_REF:0000107

NCBI chr 1:110,325,351...110,328,226
Ensembl chr 1:110,326,843...110,327,442

C1GALT1C1

C1GALT1 specific chaperone 1

(MGI:5448092|PMID:22988088)

PMID:22988088

MGI:5448092

NCBI chr X:92,581,124...92,584,701
Ensembl chr X:92,581,488...92,582,444

CD40LG

CD40 ligand

involved_in

GO_REF:0000024

NCBI chr X:107,001,421...107,023,007
Ensembl chr X:107,010,890...107,023,006

CX3CL1

C-X3-C motif chemokine ligand 1

NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

(MGI:2178511|PMID:11929769)

PMID:11929769

MGI:2178511

NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939

ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

involved_in

(MGI:2178511|PMID:11929769)

PMID:11929769

GO_REF:0000107 MGI:2178511

NCBI chr 9:48,589,408...48,594,852
Ensembl chr 9:48,570,891...48,594,452

coagulation factor II, thrombin

involved_in

(PMID:21873635)
(MGI:3709713|PMID:17380206)

PMID:17380206 PMID:21873635

MGI:3709713

NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459

coagulation factor II thrombin receptor

involved_in

GO_REF:0000024

NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687

fibrinogen gamma chain

involved_in

GO_REF:0000002

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

FZD6

frizzled class receptor 6

(MGI:4398768|PMID:19901330)

PMID:19901330

MGI:4398768

NCBI chr13:4,732,541...4,771,294
Ensembl chr13:4,733,017...4,772,115

GNA13

G protein subunit alpha 13

involved_in

(MGI:3583058|PMID:14528298)

PMID:14528298

GO_REF:0000107 MGI:3583058

NCBI chr 9:14,932,341...14,972,857
Ensembl chr 9:14,932,335...14,967,881

histidine rich glycoprotein

involved_in

(PMID:19903770)

PMID:19903770

NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537

ITGB3

integrin subunit beta 3

involved_in

(PMID:15466936)

PMID:15466936

NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451

LOC403581

peptidylprolyl isomerase A (cyclophilin A) pseudogene

(MGI:6450355|PMID:24429998)

PMID:24429998

MGI:6450355

NCBI chr 7:80,937,433...80,938,175

MERTK

MER proto-oncogene, tyrosine kinase

involved_in

(MGI:3528131|PMID:15650770)

PMID:15650770

GO_REF:0000107 MGI:3528131

NCBI chr17:36,336,787...36,445,796
Ensembl chr17:36,336,861...36,445,380

P2RX1

purinergic receptor P2X 1

involved_in

(MGI:2671726|PMID:12913094)

PMID:12913094

GO_REF:0000107 MGI:2671726

NCBI chr 9:47,674,175...47,694,358
Ensembl chr 9:47,675,300...47,688,858

P2RY1

purinergic receptor P2Y1

involved_in

GO_REF:0000002

NCBI chr23:47,249,496...47,253,203
Ensembl chr23:47,249,496...47,253,203

P2RY12

purinergic receptor P2Y12

(MGI:2136079|PMID:11413167)

PMID:11413167

MGI:2136079

NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

(MGI:3577829|PMID:15834429)

PMID:15834429

MGI:3577829

NCBI chr23:34,832,661...34,955,410
Ensembl chr23:34,836,540...34,993,939

RAP2B

RAP2B, member of RAS oncogene family

involved_in

(PMID:18582561)

PMID:18582561

NCBI chr23:47,503,382...47,508,900
Ensembl chr23:47,501,371...47,503,798

SRF

serum response factor

involved_in

(MGI:4834086|PMID:20525922)

PMID:20525922

GO_REF:0000107 MGI:4834086

NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533

TREM2

triggering receptor expressed on myeloid cells 2

involved_in

(PMID:21873635)

NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174

TYRO3

TYRO3 protein tyrosine kinase

involved_in

(MGI:3528131|PMID:15650770)

UniProt
MGI

PMID:15650770

GO_REF:0000024 MGI:3528131

NCBI chr30:8,571,230...8,602,655
Ensembl chr30:8,571,475...8,598,721

UBASH3B

ubiquitin associated and SH3 domain containing B

(MGI:5811934|PMID:27609517)

PMID:9504130 PMID:10709908 PMID:10930441 PMID:17380206 PMID:21037087

PMID:27609517

MGI:5811934

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

VWF

von Willebrand factor

NOT
involved_in

ISO
ISS
IEA

(MGI:3709713|PMID:17380206)
(MGI:1861538|PMID:10930441), (MGI:4888158|PMID:21037087)

MGI
RGD
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107 MGI:1861538 MGI:3709713 MGI:4888158 RGD:1599012 RGD:1599016

NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142

WNT3A

Wnt family member 3A

(MGI:4398768|PMID:19901330)

PMID:19901330

MGI:4398768

NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412

platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTB

actin beta

involved_in

(PMID:23382103)

NCBI chr 6:12,421,006...12,424,449
Ensembl chr 6:12,418,932...12,462,845

ACTG1

actin gamma 1

involved_in

(PMID:23382103)

NCBI chr 9:635,978...638,328
Ensembl chr 9:635,978...638,328

ACTN1

actinin alpha 1

NOT|involved_in

(PMID:23434115)

PMID:23434115

NCBI chr 8:42,714,806...42,808,318
Ensembl chr 8:42,712,142...42,808,323

BLOC1S4

biogenesis of lysosomal organelles complex 1 subunit 4

involved_in

(MGI:1354542|PMID:11110696)

PMID:11110696

GO_REF:0000107 MGI:1354542

NCBI chr 3:58,822,405...58,823,770
Ensembl chr 3:58,822,482...58,823,138

CFH

complement factor H

(MGI:5883383|PMID:28057640)

PMID:28057640

MGI:5883383

NCBI chr38:2,878,677...2,956,226

CLIC1

chloride intracellular channel 1

involved_in

(PMID:23382103)

NCBI chr12:1,209,777...1,215,229
Ensembl chr12:1,209,780...1,215,229

COMP

cartilage oligomeric matrix protein

involved_in

(MGI:5694900|PMID:26045608)

PMID:26045608

GO_REF:0000107 MGI:5694900

NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625

CSRP1

cysteine and glycine rich protein 1

involved_in

(PMID:23382103)

NCBI chr 7:1,400,650...1,421,918
Ensembl chr 7:1,397,912...1,421,007

FERMT3

FERM domain containing kindlin 3

involved_in

(PMID:21873635)
(MGI:3783912|PMID:18278053)

PMID:18278053 PMID:21873635

MGI:3783912

NCBI chr18:52,833,954...52,851,775
Ensembl chr18:52,834,001...52,851,667

fibrinogen alpha chain

involved_in

GO_REF:0000107

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250

fibrinogen gamma chain

involved_in

(PMID:6281794)

PMID:6281794

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

FIBP

FGF1 intracellular binding protein

involved_in

(PMID:23382103)

NCBI chr18:51,377,757...51,381,872
Ensembl chr18:51,377,797...51,381,808

FLNA

filamin A

involved_in

(PMID:23382103)

NCBI chr X:122,058,303...122,083,467
Ensembl chr X:122,061,455...122,083,203

GATA1

GATA binding protein 1

involved_in

(MGI:3580921|PMID:15701726)

PMID:15701726

GO_REF:0000107 MGI:3580921

NCBI chr X:41,991,321...41,998,319
Ensembl chr X:41,971,582...41,998,303

GNAS

GNAS complex locus

involved_in

(PMID:12719376)

PMID:12719376

NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657

glycoprotein Ib platelet subunit alpha

NCBI chr 5:31,681,605...31,683,261

HSPB1

heat shock protein family B (small) member 1

involved_in

(PMID:23382103)

NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576

ILK

integrin linked kinase

involved_in

(PMID:23382103)

NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974

ITGA2B

integrin subunit alpha 2b

NCBI chr 9:19,049,643...19,064,019
Ensembl chr 9:19,050,001...19,063,992

ITGB3

integrin subunit beta 3

involved_in

InterPro
RGD

PMID:17924279

GO_REF:0000002 RGD:2316357

NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451

LOC403581

peptidylprolyl isomerase A (cyclophilin A) pseudogene

(MGI:6450355|PMID:24429998)

PMID:24429998

MGI:6450355

NCBI chr 7:80,937,433...80,938,175

LOC607207

myosin regulatory light polypeptide 9

involved_in

(PMID:23382103)

NCBI chr 7:69,860,472...69,871,878

LOC609402

hemoglobin subunit beta-like

involved_in

(PMID:23382103)

NCBI chr21:28,187,535...28,188,991

METAP1

methionyl aminopeptidase 1

involved_in

(PMID:23382103)

NCBI chr32:21,201,019...21,241,164
Ensembl chr32:21,192,948...21,239,996

MPL

MPL proto-oncogene, thrombopoietin receptor

NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350

MYH9

myosin heavy chain 9

involved_in

(PMID:23382103)

NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953

MYL9

myosin light chain 9

involved_in

(PMID:23382103)

NCBI chr24:25,322,800...25,329,937
Ensembl chr24:25,322,800...25,329,932

P2RY12

purinergic receptor P2Y12

involved_in

Ensembl
RGD

PMID:19028049

GO_REF:0000107 RGD:6480528

NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526

PDGFRA

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000107

NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278

PEAR1

platelet endothelial aggregation receptor 1

involved_in

(MGI:5817200|PMID:27614188)

PMID:27614188

GO_REF:0000107 MGI:5817200

NCBI chr 7:41,110,925...41,130,532
Ensembl chr 7:41,110,909...41,123,390

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

(MGI:5488558|PMID:23372168)

PMID:23372168

MGI:5488558

NCBI chr20:55,751,055...55,801,740
Ensembl chr20:55,751,158...55,799,160

PLEK

pleckstrin

involved_in

(MGI:3844782|PMID:19190246)

PMID:19190246

GO_REF:0000107 MGI:3844782

NCBI chr10:67,395,972...67,421,247
Ensembl chr10:67,395,972...67,421,247

PTPN6

protein tyrosine phosphatase non-receptor type 6

involved_in

(MGI:5494903|PMID:23509158)

PMID:23509158

GO_REF:0000107 MGI:5494903

NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937

RAP2B

RAP2B, member of RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr23:47,503,382...47,508,900
Ensembl chr23:47,501,371...47,503,798

SLC7A11

solute carrier family 7 member 11

involved_in

(MGI:79102|PMID:8699821)

PMID:8699821

GO_REF:0000107 MGI:79102

NCBI chr19:4,289,792...4,379,060
Ensembl chr19:4,289,850...4,389,048

STXBP1

syntaxin binding protein 1

involved_in

(PMID:12773094)

PMID:12773094

NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680

STXBP3

syntaxin binding protein 3

involved_in

GO_REF:0000107

NCBI chr 6:42,947,639...42,998,297
Ensembl chr 6:42,948,236...43,053,027

TLN1

talin 1

involved_in

(PMID:23382103)

NCBI chr11:52,227,286...52,260,112
Ensembl chr11:52,227,611...52,259,915

TSPAN32

tetraspanin 32

involved_in

(MGI:3804129|PMID:16720835)

UniProt
UniProt
GO_Central
Ensembl

PMID:16720835

GO_REF:0000107 MGI:3804129

NCBI chr18:46,422,499...46,438,512
Ensembl chr18:46,422,259...46,437,272

TYRO3

TYRO3 protein tyrosine kinase

involved_in

ISS
ISO
IBA
IEA

(MGI:5306558|PMID:20546121)
(PMID:21873635)

PMID:20546121 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:5306558

NCBI chr30:8,571,230...8,602,655
Ensembl chr30:8,571,475...8,598,721

UBASH3A

ubiquitin associated and SH3 domain containing A

NOT

(MGI:5811934|PMID:27609517)

PMID:27609517

MGI:5811934

NCBI chr31:36,735,790...36,778,405
Ensembl chr31:36,735,835...36,778,405

UBASH3B

ubiquitin associated and SH3 domain containing B

involved_in

(PMID:21873635)
(MGI:5811934|PMID:27609517)

PMID:21873635 PMID:27609517

MGI:5811934

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

VCL

vinculin

involved_in

(PMID:23382103)

NCBI chr 4:24,404,279...24,518,977
Ensembl chr 4:24,404,319...24,518,633

WNT3A

Wnt family member 3A

involved_in

(MGI:4398768|PMID:19901330)

PMID:19901330

GO_REF:0000107 MGI:4398768

NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412

positive regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD36

CD36 molecule

involved_in

(MGI:4850200|PMID:20978343)

PMID:20978343

GO_REF:0000107 MGI:4850200

NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639

DMTN

dematin actin binding protein

involved_in

(MGI:5465511|PMID:23060452)

PMID:23060452

GO_REF:0000107 MGI:5465511

NCBI chr25:35,163,867...35,188,761
Ensembl chr25:35,165,876...35,176,754

ENPP4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

GO_REF:0000107

NCBI chr12:14,353,355...14,366,506
Ensembl chr12:14,353,282...14,365,952

F12

coagulation factor XII

involved_in

GO_REF:0000107

NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025

coagulation factor II, thrombin

involved_in

PMID:20664909 PMID:21873635

(PMID:21873635)

GO_Central
RGD

RGD:10449431

NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459

PMID:18305483 PMID:21873635

coagulation factor II thrombin receptor

involved_in

ISS
ISO
IBA

(MGI:3784647|PMID:18305483)
(PMID:21873635)

UniProt
MGI
GO_Central

GO_REF:0000024 MGI:3784647

NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687

coagulation factor VII

NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024

HPSE

heparanase

involved_in

GO_REF:0000107

NCBI chr32:7,166,437...7,199,659
Ensembl chr32:7,167,856...7,199,665

NFE2L2

nuclear factor, erythroid 2 like 2

involved_in

(MGI:4850200|PMID:20978343)

PMID:20978343

GO_REF:0000107 MGI:4850200

NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524

PRDX2

peroxiredoxin 2

involved_in

(MGI:4850200|PMID:20978343)

PMID:20978343

GO_REF:0000107 MGI:4850200

NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682

S100A9

S100 calcium binding protein A9

(MGI:5582990|PMID:24691441)

CACAO

PMID:24691441

MGI:5582990

NCBI chr 7:43,566,993...43,570,074

SERPINE1

serpin family E member 1

involved_in

(PMID:9207454)

PMID:9207454

NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301

ST3GAL4

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

involved_in

(MGI:2447421|PMID:12097641)

PMID:12097641

GO_REF:0000107 MGI:2447421

NCBI chr 5:8,132,663...8,160,008
Ensembl chr 5:8,133,085...8,141,254

TBXA2R

thromboxane A2 receptor

NCBI chr20:55,819,866...55,829,395
Ensembl chr20:55,824,410...55,828,980

THBS1

thrombospondin 1

involved_in

(PMID:3997886)

PMID:3997886

NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915

positive regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F11

coagulation factor XI

involved_in

GO_REF:0000107

NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292

F12

coagulation factor XII

involved_in

GO_REF:0000107

NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025

KLKB1

kallikrein B1

involved_in

(PMID:89876)

PMID:89876

NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292

plasminogen

involved_in

GO_REF:0000107

NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260

positive regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2RL1

F2R like trypsin receptor 1

involved_in

PMID:12644441

NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180

GAS6

growth arrest specific 6

involved_in

PMID:18374201

NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875

GJA1

gap junction protein alpha 1

NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936

PDGFB

platelet derived growth factor subunit B

involved_in

(MGI:3039044|PMID:15084468)

PMID:15084468

GO_REF:0000024 MGI:3039044

NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746

positive regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COMT

catechol-O-methyltransferase

NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008

PRL

prolactin

involved_in

(PMID:21873635)

NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824

XBP1

X-box binding protein 1

(MGI:5496939|PMID:23623498)

PMID:23623498

MGI:5496939

NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105

positive regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA3

adenosine A3 receptor

(MGI:3051181|PMID:15240734)

PMID:15240734

MGI:3051181

NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666

ALOX12B

arachidonate 12-lipoxygenase, 12R type

involved_in

GO_REF:0000107

NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552

ATG5

autophagy related 5

involved_in

(MGI:5548044|PMID:24185898)

GO_REF:0000107 MGI:5548044

NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485

ATG7

autophagy related 7

(MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800

CYBA

cytochrome b-245 alpha chain

(MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893

EGFR

epidermal growth factor receptor

NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631

MAP1LC3B

microtubule associated protein 1 light chain 3 beta

(MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr 5:65,669,553...65,683,445

P2RY2

purinergic receptor P2Y2

involved_in

(MGI:3833522|PMID:17728398)

InterPro
MGI

PMID:17728398

GO_REF:0000002 MGI:3833522

NCBI chr21:24,987,568...25,009,754
Ensembl chr21:24,992,848...24,996,059

PRKCE

protein kinase C epsilon

involved_in

(MGI:3833522|PMID:17728398)

PMID:17728398

GO_REF:0000107 MGI:3833522

NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296

PTGER4

prostaglandin E receptor 4

PMID:11991626 PMID:18254372

RGD

RGD:10003046 RGD:10003093

NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358

SYTL2

synaptotagmin like 2

(MGI:3693417|PMID:16716193)

PMID:16716193

MGI:3693417

NCBI chr21:13,639,054...13,756,332
Ensembl chr21:13,688,338...13,755,414

positive regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

VAMP8

vesicle associated membrane protein 8

(MGI:3801544|PMID:18535671)

PMID:18535671

MGI:3801544

NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739

positive regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NR1H2

nuclear receptor subfamily 1 group H member 2

involved_in

(MGI:3822255|PMID:18806227)

PMID:18806227

GO_REF:0000107 MGI:3822255

NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135

secretin

serine peptidase inhibitor Kazal type 1

NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706

positive regulation of pancreatic trypsinogen secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MMP13

matrix metallopeptidase 13

NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121

positive regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

podoplanin

NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375

PLA2G4A

phospholipase A2 group IVA

involved_in

GO_REF:0000107

NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936

PLEK

pleckstrin

involved_in

(MGI:3844782|PMID:19190246)

PMID:19190246

GO_REF:0000107 MGI:3844782

NCBI chr10:67,395,972...67,421,247
Ensembl chr10:67,395,972...67,421,247

PTPRJ

protein tyrosine phosphatase receptor type J

(MGI:3847185|PMID:19246339)

PMID:19246339

MGI:3847185

NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308

SELP

selectin P

involved_in

(MGI:3838274|PMID:16514062)

PMID:16514062

GO_REF:0000107 MGI:3838274

NCBI chr 7:28,956,428...28,997,266
Ensembl chr 7:28,958,486...28,996,313

TLR4

toll like receptor 4

involved_in

(MGI:3838274|PMID:16514062)

PMID:16514062

GO_REF:0000107 MGI:3838274

NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165

positive regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DMTN

dematin actin binding protein

involved_in

(MGI:5465511|PMID:23060452)

PMID:23060452

GO_REF:0000107 MGI:5465511

NCBI chr25:35,163,867...35,188,761
Ensembl chr25:35,165,876...35,176,754

F11R

F11 receptor

involved_in

GO_Central
UniProt
UniProt

GO_REF:0000107

NCBI chr38:21,433,819...21,456,722
Ensembl chr38:21,451,952...21,454,959

PDPN

podoplanin

involved_in

IBA
ISO
ISS

(PMID:21873635)
(MGI:4453945|PMID:20110424)
(MGI:3722196|PMID:17616532)

PMID:17616532 PMID:20110424 PMID:21873635

GO_REF:0000024 MGI:3722196 MGI:4453945

NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375

positive regulation of renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

(MGI:5299272|PMID:21938401)

PMID:21938401

GO_REF:0000024 MGI:5299272

NCBI chr 9:45,660,445...45,680,407
Ensembl chr 9:45,660,446...45,680,363

positive regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor beta 1

NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000024

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

TAC1

tachykinin precursor 1

NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258

TAC4

tachykinin precursor 4

(MGI:1926622|PMID:11062498)

PMID:11062498

MGI:1926622

NCBI chr 9:25,886,197...25,890,083
Ensembl chr 9:25,882,360...25,889,956

TACR1

tachykinin receptor 1

NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971

positive regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2A

adenosine A2a receptor

in renal medulla

NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598

betacellulin

NCBI chr15:64,133,051...64,159,155
Ensembl chr15:64,135,920...64,158,970

DRD2

dopamine receptor D2

involved_in

(MGI:3608592|PMID:11566895)

PMID:11566895

GO_REF:0000107 MGI:3608592

NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241

EDN1

endothelin 1

involved_in

(MGI:3612779|PMID:15632412)

PMID:15632412

GO_REF:0000107 MGI:3612779

NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383

EDNRB

endothelin receptor type B

NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587

GNAI2

G protein subunit alpha i2

NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697

HAS2

hyaluronan synthase 2

involved_in

PMID:19635555

GO_REF:0000024 RGD:8553259

NCBI chr13:20,310,946...20,342,647
Ensembl chr13:20,309,872...20,341,636

HYAL2

hyaluronidase 2

involved_in

PMID:19635555

GO_REF:0000024 RGD:8553259

NCBI chr20:39,029,426...39,034,451
Ensembl chr20:39,031,735...39,034,130

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

(MGI:5299272|PMID:21938401)

PMID:21938401

GO_REF:0000024 MGI:5299272

NCBI chr 9:45,660,445...45,680,407
Ensembl chr 9:45,660,446...45,680,363

NPPB

natriuretic peptide B

NCBI chr 2:84,395,844...84,397,473

NPR3

natriuretic peptide receptor 3

involved_in

(MGI:1339924|PMID:10377427)

PMID:10377427

GO_REF:0000107 MGI:1339924

NCBI chr 4:74,794,553...74,863,344
Ensembl chr 4:74,799,857...74,862,969

OPRL1

opioid related nociceptin receptor 1

NCBI chr24:47,530,039...47,537,477
Ensembl chr24:47,508,136...47,537,250

PTGER3

prostaglandin E receptor 3

(MGI:1328864|PMID:9843913)

PMID:9843913

MGI:1328864

NCBI chr 6:74,932,789...74,986,573

PTGER4

prostaglandin E receptor 4

NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358

TFAP2B

transcription factor AP-2 beta

involved_in

ISS
ISO
IEA

(MGI:2656435|PMID:12695560)

UniProt
UniProt
Ensembl

PMID:12695560

GO_REF:0000024 GO_REF:0000107 MGI:2656435

NCBI chr12:18,544,176...18,574,300
Ensembl chr12:18,544,446...18,572,902

regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

(MGI:1933877|PMID:11145969)

PMID:11145969

MGI:1933877

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

CAV1

caveolin 1

involved_in

GO_REF:0000107

NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935

EPHB2

EPH receptor B2

involved_in

GO_REF:0000107

NCBI chr 2:76,427,112...76,551,494
Ensembl chr 2:76,428,203...76,612,786

F11

coagulation factor XI

(MGI:3719506|PMID:16533887)

PMID:16533887

MGI:3719506

NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292

coagulation factor II thrombin receptor

involved_in

(PMID:17848177)

PMID:17848177

NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180

FOXA2

forkhead box A2

involved_in

GO_REF:0000107

NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072

histidine rich glycoprotein

involved_in

(MGI:3789419|PMID:15869579)
(PMID:21304106), (PMID:6740558)

PMID:6740558 PMID:15869579 PMID:21304106

MGI:3789419

NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537

SERPING1

serpin family G member 1

involved_in

GO_REF:0000002

NCBI chr18:38,570,354...38,580,751
Ensembl chr18:38,570,607...38,581,665

VKORC1

vitamin K epoxide reductase complex subunit 1

NCBI chr 6:17,140,565...17,142,621
Ensembl chr 6:17,140,633...17,142,547

regulation of blood coagulation, intrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SERPINC1

serpin family C member 1

involved_in

GO_REF:0000002

NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987

regulation of blood volume by renal aldosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP11B2

cytochrome P450, family 11, subfamily B, polypeptide 2

involved_in

PMID:14614232 PMID:16118390

(MGI:3611121|PMID:16118390)
(PMID:14614232)

MGI
BHF-UCL

MGI:3611121

NCBI chr13:36,866,476...36,880,625

HSD11B2

hydroxysteroid 11-beta dehydrogenase 2

NCBI chr 5:81,966,397...81,970,301
Ensembl chr 5:81,966,937...81,968,991

regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:16480936)

PMID:16480936

NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185

regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA1

adenosine A1 receptor

involved_in

(MGI:3606554|PMID:15283758)

PMID:15283758

GO_REF:0000107 MGI:3606554

NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051

CORO2B

coronin 2B

involved_in

(MGI:6110508|PMID:29162887)

PMID:29162887

GO_REF:0000107 MGI:6110508

NCBI chr30:32,574,068...32,701,494
Ensembl chr30:32,627,373...32,702,757

EMP2

epithelial membrane protein 2

involved_in

UniProt
UniProt
GO_Central

GO_REF:0000107

NCBI chr 6:32,026,908...32,060,447
Ensembl chr 6:32,026,916...32,057,693

PTPRO

protein tyrosine phosphatase receptor type O

involved_in

ISS
ISO
IBA

(MGI:1927435|PMID:11086029)
(PMID:21873635)

PMID:11086029 PMID:21873635

GO_REF:0000024 MGI:1927435

NCBI chr27:31,082,334...31,322,024
Ensembl chr27:31,084,544...31,322,022

regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

OAS2

2'-5'-oligoadenylate synthetase 2

involved_in

(MGI:6094812|PMID:29117179)

PMID:29117179

GO_REF:0000107 MGI:6094812

NCBI chr26:10,431,881...10,450,085
Ensembl chr26:10,432,042...10,449,009

regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NLRP6

NLR family pyrin domain containing 6

involved_in

(MGI:5577214|PMID:24581500)

PMID:24581500

GO_REF:0000107 MGI:5577214

NCBI chr18:25,433,481...25,440,703
Ensembl chr18:25,433,698...25,440,740

regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FCER1G

Fc fragment of IgE receptor Ig

involved_in

(MGI:87668|PMID:9171347)

PMID:9171347

GO_REF:0000107 MGI:87668

NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940

histidine rich glycoprotein

involved_in

(PMID:21873635)
(MGI:3789419|PMID:15869579), (MGI:4941083|PMID:21264222)

PMID:15869579 PMID:21264222 PMID:21873635

MGI:3789419 MGI:4941083

NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537

SYK

spleen associated tyrosine kinase

(MGI:87668|PMID:9171347)

PMID:9171347

MGI:87668

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

TEC

tec protein tyrosine kinase

involved_in

(PMID:21873635)

NCBI chr13:43,978,964...44,111,256
Ensembl chr13:43,978,573...44,062,795

TXK

TXK tyrosine kinase

involved_in

(PMID:21873635)

NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655

regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BLK

BLK proto-oncogene, Src family tyrosine kinase

involved_in

(PMID:21873635)

NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015

LYN

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_Central
UniProt
Ensembl

(PMID:21873635)
(MGI:5298337|PMID:20189992)

PMID:20189992 PMID:21873635

GO_REF:0000107 MGI:5298337

NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507

PRKCA

protein kinase C alpha

involved_in

(MGI:3836381|PMID:19147982)

PMID:19147982

GO_REF:0000107 MGI:3836381

NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630

PRKCQ

protein kinase C theta

involved_in

(MGI:3851048|PMID:19433059)

PMID:19433059

GO_REF:0000107 MGI:3851048

NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337

SYK

spleen associated tyrosine kinase

involved_in

GO_Central
UniProt
Ensembl

(PMID:21873635)
(MGI:87668|PMID:9171347)

PMID:9171347 PMID:21873635

GO_REF:0000107 MGI:87668

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

VPS33B

VPS33B late endosome and lysosome associated

involved_in

(MGI:5645581|PMID:25947942)

PMID:25947942

GO_REF:0000107 MGI:5645581

NCBI chr 3:53,220,199...53,239,738
Ensembl chr 3:53,220,194...53,239,732

regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGF10

fibroblast growth factor 10

involved_in

GO_REF:0000107

NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192

OPRK1

opioid receptor kappa 1

(MGI:1197118|PMID:9463367)

PMID:9463367

MGI:1197118

NCBI chr29:5,022,270...5,054,223
Ensembl chr29:5,025,786...5,051,919

regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADM

adrenomedullin

involved_in

GO_REF:0000107

NCBI chr21:33,472,197...33,474,472
Ensembl chr21:33,471,623...33,474,495

ADM5

adrenomedullin 5 (putative)

involved_in

(PMID:18434369)

PMID:18434369

NCBI chr 1:106,847,706...106,849,147
Ensembl chr 1:106,847,633...106,848,510

AKR1B1

aldo-keto reductase family 1 member B

(MGI:3628967|PMID:16449351)

PMID:16449351

MGI:3628967

NCBI chr14:2,991,888...3,006,941
Ensembl chr14:2,991,888...3,006,940

TRPV5

transient receptor potential cation channel subfamily V member 5

involved_in

(MGI:2682494|PMID:14679186)

PMID:14679186

GO_REF:0000107 MGI:2682494

NCBI chr16:6,647,070...6,678,080
Ensembl chr16:6,650,574...6,676,963

UMOD

uromodulin

involved_in

(MGI:6094531|PMID:29145399), (MGI:6367886|PMID:29357410)

PMID:29145399 PMID:29357410

GO_REF:0000107 MGI:6094531 MGI:6367886

NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735

regulation of water loss via skin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACER1

alkaline ceramidase 1

involved_in

(MGI:5800647|PMID:27126290)

PMID:27126290

GO_REF:0000107 MGI:5800647

NCBI chr20:53,819,224...53,838,183
Ensembl chr20:53,819,074...53,838,438

CDH1

cadherin 1

(MGI:3574751|PMID:15775979)

PMID:15775979

MGI:3574751

NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878

GBA

glucosylceramidase beta

NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864

LOC482174

transmembrane protease serine 11F

involved_in

(MGI:6363614|PMID:31501243)
(MGI:6296037|PMID:28338078)

PMID:28338078 PMID:31501243

GO_REF:0000107 MGI:6296037 MGI:6363614

NCBI chr13:58,550,709...58,637,729
Ensembl chr13:58,551,902...58,638,086

SRF

serum response factor

involved_in

(MGI:4421610|PMID:20047077)

PMID:20047077

GO_REF:0000107 MGI:4421610

NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533

renal water absorption

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

PMID:9468475 PMID:10021457 PMID:10662735 PMID:10724035 PMID:10795927 PMID:11035042 PMID:12133842 PMID:15998844 PMID:16525162

GO_REF:0000107 MGI:1196668 MGI:1353208 MGI:1354610 MGI:1858888 MGI:1929327 MGI:2387728 MGI:3607623 MGI:3640845 MGI:3700886

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AQP3

aquaporin 3

(MGI:1858888|PMID:10795927), (MGI:1929327|PMID:11035042)
(MGI:1929327|PMID:11035042)

PMID:10795927 PMID:11035042

MGI:1858888 MGI:1929327

NCBI chr11:50,517,509...50,524,565

AQP4

aquaporin 4

(MGI:1353208|PMID:10662735)
(MGI:1353208|PMID:10662735), (MGI:1858888|PMID:10795927)

PMID:10662735 PMID:10795927

MGI:1353208 MGI:1858888

NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089

AQP7

aquaporin 7

(MGI:3607623|PMID:15998844)

PMID:15998844

MGI:3607623

NCBI chr11:50,474,007...50,488,191

HAS2

hyaluronan synthase 2

involved_in

PMID:19635555

GO_REF:0000024 RGD:8553259

NCBI chr13:20,310,946...20,342,647
Ensembl chr13:20,309,872...20,341,636

HYAL2

hyaluronidase 2

involved_in

PMID:19635555

GO_REF:0000024 RGD:8553259

NCBI chr20:39,029,426...39,034,451
Ensembl chr20:39,031,735...39,034,130

SCTR

secretin receptor

(MGI:3709930|PMID:17283064)

PMID:17283064

MGI:3709930

NCBI chr19:30,505,059...30,577,371
Ensembl chr19:30,526,055...30,577,075

renal water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

(MGI:4457984|PMID:20466003)

PMID:20466003

GO_REF:0000024 MGI:4457984

NCBI chr27:5,739,514...5,752,888
Ensembl chr27:5,733,586...5,752,888

AKAP11

A-kinase anchoring protein 11

involved_in

(MGI:5792167|PMID:27402760)

PMID:27402760

GO_REF:0000107 MGI:5792167

NCBI chr22:8,462,058...8,509,660
Ensembl chr22:8,465,797...8,509,955

AKR1B1

aldo-keto reductase family 1 member B

(MGI:3628967|PMID:16449351)

PMID:16449351

MGI:3628967

NCBI chr14:2,991,888...3,006,941
Ensembl chr14:2,991,888...3,006,940

AQP2

aquaporin 2

involved_in

PMID:8140421 PMID:27402760

(MGI:5792167|PMID:27402760)
(PMID:8140421)

MGI
UniProt

MGI:5792167

NCBI chr27:4,743,127...4,750,907
Ensembl chr27:4,743,127...4,750,907

ATP6V1B1

ATPase H+ transporting V1 subunit B1

(MGI:5529401|PMID:24051376)

PMID:24051376

MGI:5529401

NCBI chr10:69,261,311...69,287,540
Ensembl chr10:69,252,926...69,287,542

TFAP2B

transcription factor AP-2 beta

involved_in

ISS
ISO
IEA

(MGI:2656435|PMID:12695560)

UniProt
UniProt
Ensembl

PMID:12695560

GO_REF:0000024 GO_REF:0000107 MGI:2656435

NCBI chr12:18,544,176...18,574,300
Ensembl chr12:18,544,446...18,572,902

UMOD

uromodulin

involved_in

(MGI:3531218|PMID:15522986)

PMID:15522986

GO_REF:0000107 MGI:3531218

NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735

WFS1

wolframin ER transmembrane glycoprotein

involved_in

(PMID:9817917)

PMID:9817917

NCBI chr13:38,451,722...38,466,481
Ensembl chr13:38,451,710...38,475,827

renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

ISS
IBA

(PMID:21873635)

UniProt
GO_Central

GO_REF:0000024

NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720

AQP2

aquaporin 2

involved_in

(MGI:57911|PMID:3184310)

PMID:3184310

GO_REF:0000107 MGI:57911

NCBI chr27:4,743,127...4,750,907
Ensembl chr27:4,743,127...4,750,907

saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AQP5

aquaporin 5

(MGI:1340782|PMID:10400615), (MGI:1858888|PMID:10795927), (MGI:3612624|PMID:15647389)

PMID:10400615 PMID:10795927 PMID:15647389

MGI:1340782 MGI:1858888 MGI:3612624

NCBI chr27:4,735,313...4,742,975
Ensembl chr27:4,735,538...4,737,650

CHRM1

cholinergic receptor muscarinic 1

involved_in

GO_REF:0000002

NCBI chr18:53,783,938...53,797,750
Ensembl chr18:53,795,326...53,796,708

CHRM3

cholinergic receptor muscarinic 3

involved_in

PMID:8973172 PMID:16873365

(MGI:1888655|PMID:10944224)

InterPro
MGI

PMID:10944224

GO_REF:0000002 MGI:1888655

NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613

KCNMA1

potassium calcium-activated channel subfamily M alpha 1

involved_in

ISA
ISO

(PMID:8973172)
(MGI:3695228|PMID:16873365)

AgBase
MGI

MGI:3695228

NCBI chr 4:26,844,250...27,338,271
Ensembl chr 4:26,844,250...27,555,776

KCNN4

potassium calcium-activated channel subfamily N member 4

involved_in

(MGI:3695228|PMID:16873365)

PMID:16873365

GO_REF:0000107 MGI:3695228

NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701

TRPC1

transient receptor potential cation channel subfamily C member 1

(MGI:3762998|PMID:17956991)

PMID:17956991

MGI:3762998

NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464

tear secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGF10

fibroblast growth factor 10

involved_in

GO_REF:0000107

NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192

LACRT

lacritin

involved_in