regulation of body fluid levels - Ontology Report

GO_REF:0000107
MGI:2148676 (MGI:1931986|PMID:11133517)

PMID:11133517

GO_REF:0000107 MGI:1931986

NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148

Ephb2

Eph receptor B2

involved_in

(MGI:1859095|PMID:10839360)

PMID:10839360

MGI:1859095

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

Heg1

heart development protein with EGF-like domains 1

acts_upstream_of_or_within

MGI:3838392 (MGI:3837878|PMID:19151727)

PMID:19151727

MGI:3837878

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

Nppa

natriuretic peptide A

RGD

PMID:11751587

RGD:70434

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

Pdss2

decaprenyl diphosphate synthase subunit 2

acts_upstream_of_or_within

MGI:1856927 (MGI:53710|PMID:5098070)

PMID:5098070

MGI:53710

NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708

relaxin 1

RGD

NCBI chr 1:227,079,960...227,082,960
Ensembl chr 1:227,079,966...227,082,882

Scnn1a

sodium channel epithelial 1 subunit alpha

RGD

PMID:16258001

RGD:1624122

NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181

activation of blood coagulation via clotting cascade

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ano6

anoctamin 6

involved_in

(PMID:21107324)

PMID:21107324

NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589

blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ano6

anoctamin 6

involved_in

(MGI:5440105|PMID:23021219)

PMID:23021219

MGI:5440105

NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589

Anxa5

annexin A5

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

Anxa8

annexin A8

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043

Ap3b1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within

MGI:1856989 (MGI:55798|PMID:6696991)

NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935

apolipoprotein H

RGD

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

Bloc1s3

biogenesis of lysosomal organelles complex-1, subunit 3

acts_upstream_of_or_within

MGI:1857021 (MGI:3522060|PMID:15265785)

PMID:15265785

MGI:3522060

NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505

Bloc1s6

biogenesis of lysosomal organelles complex 1 subunit 6

acts_upstream_of_or_within

MGI:1856982 (MGI:55798|PMID:6696991)

NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308

complement C3

RGD

PMID:15956288

RGD:1625334

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

complement C9

RGD

PMID:15956288

RGD:1625334

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Comp

cartilage oligomeric matrix protein

acts_upstream_of_or_within

MGI:2180787 (MGI:5694900|PMID:26045608)

PMID:26045608

MGI:5694900

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

Cpb2

carboxypeptidase B2

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

Dtnbp1

dystrobrevin binding protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856628 (MGI:50482|PMID:1936982)

PMID:1936982

GO_REF:0000107 MGI:50482

NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661

Enpp4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

GO_REF:0000043

PMID:10048754 PMID:21873635

GO_REF:0000043

NCBI chr 9:16,888,923...16,898,860
Ensembl chr 9:16,887,739...16,898,860

F10

coagulation factor X

involved_in

IDA
IBA
IEA

PMID:21873635
GO_REF:0000043

UniProt
RGD

GO_REF:0000043, RGD:2290183, RGD:13792537

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

coagulation factor XI

involved_in

TAS
ISO
IDA

(PMID:9169594)

PMID:9169594 PMID:10899350 PMID:10048754

RGD:1598920, RGD:2290183

NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437

coagulation factor XII

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA
IEA

MGI:3720935 (MGI:3720875|PMID:15351846)
PMID:21873635
GO_REF:0000107

PMID:15351846 PMID:10048754 PMID:21873635

GO_REF:0000107 MGI:3720875, RGD:2290183, RGD:13792537

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

F13a1

coagulation factor XIII A1 chain

acts_upstream_of_or_within

IDA
ISO

MGI:2684302 (MGI:2684288|PMID:12529747)

PMID:12529747 PMID:420942

MGI:2684288, RGD:1582287

NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700

F13b

coagulation factor XIII B chain

involved_in

MGI:5645820 (MGI:5645809|PMID:18224415)

PMID:18224415

MGI:5645809

NCBI chr13:51,130,851...51,156,383
Ensembl chr13:51,130,920...51,156,381

coagulation factor II

RGD

PMID:10048754

RGD:2290183

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

coagulation factor II (thrombin) receptor

RGD

PMID:12372796

RGD:728482

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

F2rl1

F2R like trypsin receptor 1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

F2rl2

coagulation factor II (thrombin) receptor-like 2

involved_in

GO_REF:0000043
GO_REF:0000002

UniProt
InterPro

GO_REF:0000002 GO_REF:0000043

NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098

F2rl3

F2R like thrombin or trypsin receptor 3

involved_in

GO_REF:0000002
GO_REF:0000043

InterPro
UniProt

GO_REF:0000002 GO_REF:0000043

NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472

coagulation factor III, tissue factor

involved_in

GO_REF:0000107
(PMID:24998411), (PMID:8632006)

PMID:8632006 PMID:24998411

GO_REF:0000107

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

coagulation factor V

acts_upstream_of_or_within

IDA
ISO

MGI:1931525 (MGI:2678846|PMID:12816857), (MGI:2678880|PMID:12855561), (MGI:83870|PMID:8900278)

PMID:8900278 PMID:12816857 PMID:12855561 PMID:10048754

MGI:2678846 MGI:2678880 MGI:83870, RGD:2290183

NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317

coagulation factor VII

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA

MGI:2182766 (MGI:1099680|PMID:9384381)
PMID:21873635
(PMID:24998411), (PMID:8632006)

PMID:8632006 PMID:9384381 PMID:24998411 PMID:10048754 PMID:21873635

MGI:1099680, RGD:2290183, RGD:13792537

NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610

coagulation factor VIII

RGD

PMID:10048754

RGD:2290183

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

coagulation factor IX

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA

MGI:3055509 (MGI:3055261|PMID:15178576)
PMID:21873635
(PMID:20121197), (PMID:2472424), (PMID:2592373)

MGI:3055261, RGD:2290183, RGD:13792537

PMID:2472424 PMID:2592373 PMID:15178576 PMID:20121197 PMID:10048754 More...

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

fibrinogen alpha chain

acts_upstream_of_or_within

TAS
ISO

MGI:2152976 (MGI:1861538|PMID:10930441)

PMID:10930441 PMID:8595905

MGI:1861538, RGD:728797

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

Gas6

growth arrest specific 6

acts_upstream_of_or_within

MGI:2675495 (MGI:3044336|PMID:15184064)

PMID:15184064

MGI:3044336

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

glycoprotein Ib platelet subunit alpha

acts_upstream_of_or_within
involved_in

(MGI:4888094|PMID:20650879), (MGI:4888158|PMID:21037087)
(MGI:3773462|PMID:18187573)
(PMID:21037087)

PMID:18187573 PMID:20650879 PMID:21037087

MGI:3773462 MGI:4888094 MGI:4888158

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

Gp1bb

glycoprotein Ib platelet subunit beta

involved_in

GO_REF:0000043
(MGI:3773462|PMID:18187573)

PMID:18187573

GO_REF:0000043 MGI:3773462

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

glycoprotein V (platelet)

involved_in

GO_REF:0000043
(MGI:3773462|PMID:18187573)

PMID:18187573

GO_REF:0000043 MGI:3773462

NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705

Gp9

glycoprotein IX (platelet)

involved_in

(MGI:3773462|PMID:18187573)

PMID:18187573

MGI:3773462

NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110

Habp2

hyaluronan binding protein 2

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160

Hgfac

HGF activator

involved_in

PMID:21873635

GO_Central

NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278

Hnf4a

hepatocyte nuclear factor 4, alpha

involved_in

GO_REF:0000107
(PMID:12911579)

PMID:12911579

GO_REF:0000107

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

Hps1

HPS1, biogenesis of lysosomal organelles complex 3 subunit 1

acts_upstream_of_or_within

MGI:1856712 (MGI:55798|PMID:6696991)

NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268

Hps4

HPS4, biogenesis of lysosomal organelles complex 3 subunit 2

acts_upstream_of_or_within

MGI:1856931 (MGI:55798|PMID:6696991)

NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632

Hps5

HPS5, biogenesis of lysosomal organelles complex 2 subunit 2

acts_upstream_of_or_within

MGI:1856146 (MGI:55798|PMID:6696991)

NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019

Hps6

HPS6, biogenesis of lysosomal organelles complex 2 subunit 3

acts_upstream_of_or_within

MGI:1856544 (MGI:55798|PMID:6696991)

NCBI chr 1:244,853,256...244,855,865
Ensembl chr 1:244,853,194...244,855,883

Il10rb

interleukin 10 receptor subunit beta

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

kallikrein B1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

Kng1

kininogen 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

Kng2l1

kininogen 2-like 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:77,978,795...78,002,976

Lnpk

lunapark, ER junction formation factor

acts_upstream_of_or_within

MGI:1857660 (MGI:79294|PMID:8835524)

PMID:8835524

MGI:79294

NCBI chr 3:59,418,872...59,487,029
Ensembl chr 3:59,424,286...59,486,518

Lyst

lysosomal trafficking regulator

acts_upstream_of_or_within

MGI:1855968 (MGI:55798|PMID:6696991)

NCBI chr17:86,241,384...86,443,501

Mmrn1

multimerin 1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474

Mpig6b

megakaryocyte and platelet inhibitory receptor G6b

involved_in
acts_upstream_of_or_within

IEA
ISO
ISS
IBA

GO_REF:0000107
MGI:2675830 (MGI:5512895|PMID:23112346)
GO_REF:0000024
PMID:21873635

PMID:23112346 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:5512895, RGD:13792537

NCBI chr20:3,757,396...3,761,024
Ensembl chr20:3,757,536...3,760,735

Nbeal2

neurobeachin-like 2

acts_upstream_of_or_within

MGI:5007262 (MGI:5514081|PMID:23863626)

PMID:23863626

MGI:5514081

NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707

Papss2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

acts_upstream_of_or_within

MGI:1856688 (MGI:79294|PMID:8835524)

PMID:8835524

MGI:79294

NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331

plasminogen

involved_in

(PMID:1986355)
GO_REF:0000104

PMID:1986355

GO_REF:0000104

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

Proc

protein C, inactivator of coagulation factors Va and VIIIa

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133

Procr

protein C receptor

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903

Pros1

protein S

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

Proz

protein Z, vitamin K-dependent plasma glycoprotein

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1931524 (MGI:1859486|PMID:10829076)

PMID:10829076 PMID:21873635

MGI:1859486, RGD:13792537

NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480

Prss56

serine protease 56

involved_in

PMID:21873635

GO_Central

NCBI chr 9:87,842,806...87,859,978
Ensembl chr 9:87,854,805...87,859,978

Ptprj

protein tyrosine phosphatase, receptor type, J

involved_in

(MGI:3847185|PMID:19246339)

PMID:19246339

MGI:3847185

NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260

Rab27a

RAB27A, member RAS oncogene family

acts_upstream_of_or_within

MGI:1856656 (MGI:1860659|PMID:10859366)

PMID:10859366

MGI:1860659

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

Serpina10

serpin family A member 10

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544

Serpinc1

serpin family C member 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

Serpind1

serpin family D member 1

involved_in

GO_REF:0000043
GO_REF:0000002

UniProt
InterPro

GO_REF:0000002 GO_REF:0000043

NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519

serpin family E member 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2387774 (MGI:4418017|PMID:19855083)

PMID:19855083

GO_REF:0000107 MGI:4418017

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

Serping1

serpin family G member 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

Shh

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1860897 (MGI:79294|PMID:8835524)

PMID:8835524

GO_REF:0000107 MGI:79294

NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170

Slc4a1

solute carrier family 4 member 1 (Diego blood group)

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857140 (MGI:3619187|PMID:9716609)

PMID:9716609

GO_REF:0000107 MGI:3619187

NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117

Tfpi

tissue factor pathway inhibitor

involved_in

GO_REF:0000043
GO_REF:0000104

GO_REF:0000043 GO_REF:0000104

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

Tfpi2

tissue factor pathway inhibitor 2

involved_in

GO_REF:0000104

GO_REF:0000104

NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600

Thbd

thrombomodulin

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

Tspan32

tetraspanin 32

acts_upstream_of_or_within

MGI:2183564 (MGI:3804129|PMID:16720835)

PMID:16720835

MGI:3804129

NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445

Vkorc1

vitamin K epoxide reductase complex, subunit 1

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:5559848|PMID:19492146)
GO_REF:0000024
(PMID:16270630)

PMID:16270630 PMID:19492146 PMID:21873635

GO_REF:0000024 MGI:5559848, RGD:13792537

NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008

Vwf

von Willebrand factor

acts_upstream_of_or_within
involved_in

IMP
ISO
IBA

MGI:2153009 (MGI:1276653|PMID:9689113), (MGI:3709713|PMID:17380206), (MGI:4888158|PMID:21037087)
(PMID:16409464)
PMID:21873635

PMID:9689113 PMID:16409464 PMID:17380206 PMID:21037087 PMID:10709908 More...

MGI:1276653 MGI:3709713 MGI:4888158, RGD:1599012, RGD:13792537, RGD:1599016

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

blood coagulation, common pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor II

involved_in

(PMID:22457833)

PMID:22457833

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

fibrinogen alpha chain

involved_in

(PMID:12706644)
PMID:21873635
(PMID:10891444)

PMID:10891444 PMID:12706644 PMID:21873635

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

blood coagulation, extrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor V

RGD

PMID:15172885

RGD:1601118

NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317

blood coagulation, fibrin clot formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F13a1

coagulation factor XIII A1 chain

involved_in

ISS
ISO
IEA
IBA

GO_REF:0000024
MGI:5645817 (MGI:5645809|PMID:18224415)
GO_REF:0000107
(PMID:27363989)
PMID:21873635

PMID:18224415 PMID:27363989 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:5645809, RGD:13792537

NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700

F13b

coagulation factor XIII B chain

involved_in

(PMID:27363989)
GO_REF:0000107

PMID:27363989

GO_REF:0000107

NCBI chr13:51,130,851...51,156,383
Ensembl chr13:51,130,920...51,156,381

Fbln1

fibulin 1

involved_in

(PMID:7642629)

PMID:7642629

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

fibrinogen alpha chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

(PMID:16846481)
PMID:21873635

PMID:16846481 PMID:21873635

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

fibrinogen gamma chain

involved_in

PMID:21873635
(PMID:16846481)
(PMID:11001902), (PMID:16846481)

PMID:11001902 PMID:16846481 PMID:21873635

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Fn1

fibronectin 1

involved_in

PMID:21873635

GO_Central

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

blood coagulation, intrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:4052628)
GO_REF:0000107

PMID:4052628

GO_REF:0000107

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

coagulation factor XI

involved_in

(PMID:10823824)

PMID:2513867 PMID:21873635

PMID:10823824

NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437

coagulation factor VIII

involved_in

IMP
IBA

PMID:21873635

RGD
GO_Central

RGD:1582368, RGD:13792537

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

coagulation factor IX

involved_in

(PMID:8632006)

PMID:8632006

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:10501658)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

Gp1bb

glycoprotein Ib platelet subunit beta

involved_in

(PMID:10501658)
GO_REF:0000107

GO_REF:0000107

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

glycoprotein V (platelet)

involved_in

(PMID:10501658)

NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705

Gp9

glycoprotein IX (platelet)

involved_in

(PMID:10501658)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110

kallikrein B1

involved_in

(PMID:874082)

PMID:874082

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

body fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A2

RGD

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

Clcnka

chloride voltage-gated channel Ka

RGD

PMID:7680033

RGD:68767

NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148

Edn1

endothelin 1

acts_upstream_of_or_within

MGI:3044563|MGI:3054057 (MGI:3051206|PMID:15314687)

PMID:15314687

MGI:3051206

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Guca2b

guanylate cyclase activator 2B

acts_upstream_of_or_within

MGI:2679505 (MGI:2678878|PMID:14561709)

PMID:14561709

MGI:2678878

NCBI chr 5:133,246,891...133,248,941
Ensembl chr 5:133,246,909...133,248,966

Rab14

RAB14, member RAS oncogene family

RGD

PMID:18332131

RGD:2306298

NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172

Tsc22d3

TSC22 domain family, member 3

RGD

PMID:12707381

RGD:632721

NCBI chr X:104,217,898...104,277,935
Ensembl chr X:104,217,925...104,276,861

cerebrospinal fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1

involved_in

(PMID:16814974)

PMID:16814974

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Aqp4

aquaporin 4

involved_in

(MGI:6277731|PMID:30293570)

PMID:30293570

MGI:6277731

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

Celsr2

cadherin, EGF LAG seven-pass G-type receptor 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1858236 (MGI:4460066|PMID:20473291)

PMID:20473291

GO_REF:0000107 MGI:4460066

NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845

Slc4a5

solute carrier family 4 member 5

acts_upstream_of_or_within

(MGI:5292606|PMID:21705333)

PMID:21705333

MGI:5292606

NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323

Tp73

tumor protein p73

acts_upstream_of_or_within

MGI:1859911 (MGI:1354064|PMID:10716451)

PMID:10716451

MGI:1354064

NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128

establishment of skin barrier

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abca12

ATP binding cassette subfamily A member 12

acts_upstream_of_or_within
involved_in

PMID:18632686 PMID:18802465 PMID:18957418 PMID:20489143 PMID:27551807

MGI:3807143 MGI:3829841 MGI:4460077 MGI:4462766 MGI:6161848

NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049

Alox12

arachidonate 12-lipoxygenase, 12S type

involved_in

GO_REF:0000024
(MGI:1339275|PMID:10383730)

PMID:10383730

GO_REF:0000024 MGI:1339275

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

Alox12b

arachidonate 12-lipoxygenase, 12R type

involved_in

GO_REF:0000024
(MGI:3789553|PMID:17403930), (MGI:5141179|PMID:21558561)
GO_REF:0000107

PMID:17403930 PMID:21558561

GO_REF:0000024 GO_REF:0000107 MGI:3789553 MGI:5141179

NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938

Aloxe3

arachidonate lipoxygenase 3

involved_in

GO_REF:0000024
(MGI:5488571|PMID:22832496)

PMID:22832496

GO_REF:0000024 MGI:5488571

NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328

Cela2a

chymotrypsin like elastase 2A

acts_upstream_of_or_within

MGI:5523057 (MGI:4440399|PMID:20179351)

PMID:20179351

MGI:4440399

NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632

Cldn1

claudin 1

involved_in

(PMID:23407391)
(MGI:2176640|PMID:11889141)
GO_REF:0000024

PMID:11889141 PMID:23407391

GO_REF:0000024 MGI:2176640

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

Cldn4

claudin 4

involved_in

(PMID:23407391)

PMID:23407391

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

acts_upstream_of_or_within

MGI:3039046 (MGI:5466369|PMID:22366455)

PMID:22366455

MGI:5466369

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

Elovl1

ELOVL fatty acid elongase 1

involved_in

(MGI:5532629|PMID:23689133)

PMID:23689133

MGI:5532629

NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958

Fa2h

fatty acid 2-hydroxylase

involved_in

GO_REF:0000024
(PMID:17355976)

PMID:17355976

GO_REF:0000024

NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153

Flg

filaggrin

involved_in
acts_upstream_of_or_within

(PMID:23403047)
MGI:1856880 (MGI:5466369|PMID:22366455)

PMID:22366455 PMID:23403047

MGI:5466369

NCBI chr 2:178,888,688...178,912,731

Flg2

filaggrin 2

involved_in

(PMID:23403047)
PMID:21873635

PMID:23403047 PMID:21873635

NCBI chr 2:178,789,792...178,802,232

Gak

cyclin G associated kinase

acts_upstream_of_or_within

MGI:2176228|MGI:5305733 (MGI:5305417|PMID:18434600)

PMID:18434600

MGI:5305417

NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398

Grhl1

grainyhead-like transcription factor 1

acts_upstream_of_or_within

MGI:3778923 (MGI:5585711|PMID:24586629)

PMID:24586629

MGI:5585711

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

Grhl3

grainyhead-like transcription factor 3

involved_in

(MGI:5617425|PMID:25347468)

PMID:25347468

MGI:5617425

NCBI chr 5:147,774,160...147,806,338
Ensembl chr 5:147,774,160...147,806,160

Hrnr

hornerin

involved_in

PMID:21873635
(PMID:23403047)

PMID:23403047 PMID:21873635

Kdf1

keratinocyte differentiation factor 1

involved_in

GO_REF:0000024
(MGI:5529391|PMID:24075906)

PMID:24075906

GO_REF:0000024 MGI:5529391

NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878

Krt1

keratin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:5495252 (MGI:5507924|PMID:23132931)

PMID:23132931

GO_REF:0000107 MGI:5507924

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

Krt16

keratin 16

involved_in

(MGI:5523704|PMID:24218583)

PMID:24218583

MGI:5523704

NCBI chr10:85,168,357...85,171,744

Lsr

lipolysis stimulated lipoprotein receptor

involved_in

(MGI:6316553|PMID:21245199)

PMID:21245199

MGI:6316553

NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952

Met

MET proto-oncogene, receptor tyrosine kinase

involved_in

(PMID:25198505)
GO_REF:0000107

PMID:25198505

GO_REF:0000107

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Plec

plectin

involved_in

MGI:3721885 (MGI:3721038|PMID:17606998)
GO_REF:0000107

PMID:17606998

GO_REF:0000107 MGI:3721038

NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467

Pnpla1

patatin-like phospholipase domain containing 1

involved_in

(MGI:5882269|PMID:27751867), (MGI:5888934|PMID:28248300)

PMID:27751867 PMID:28248300

MGI:5882269 MGI:5888934

NCBI chr20:6,918,446...6,951,650
Ensembl chr20:6,917,931...6,952,375

Sfn

stratifin

involved_in

(MGI:5529391|PMID:24075906)

PMID:24075906

MGI:5529391

Ensembl chr 5:145,826,201...145,831,314

Stard7

StAR-related lipid transfer domain containing 7

acts_upstream_of_or_within

MGI:4433666 (MGI:5906122|PMID:25980009)

PMID:25980009

MGI:5906122

NCBI chr 3:114,487,163...114,515,825
Ensembl chr 3:114,485,600...114,515,813

Stmn1

stathmin 1

involved_in

(PMID:25198505)

PMID:25198505

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

Tmem79

transmembrane protein 79

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:5518480|PMID:24060273)
MGI:1856947 (MGI:5519142|PMID:24084074)

PMID:24060273 PMID:24084074

GO_REF:0000024 MGI:5518480 MGI:5519142

NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046

Tmprss13

transmembrane serine protease 13

acts_upstream_of_or_within

MGI:3663353 (MGI:5604957|PMID:24832573)

PMID:24832573

MGI:5604957

NCBI chr 8:45,625,759...45,653,943
Ensembl chr 8:45,625,626...45,653,938

Tp63

tumor protein p63

involved_in

GO_REF:0000024
(MGI:5529391|PMID:24075906)

PMID:24075906

GO_REF:0000024 MGI:5529391

NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398

Ugcg

UDP-glucose ceramide glucosyltransferase

involved_in

GO_REF:0000024
(MGI:3706199|PMID:17145749)

PMID:17145749

GO_REF:0000024 MGI:3706199

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa2

annexin A2

acts_upstream_of_or_within

MGI:3028929 (MGI:3027337|PMID:14702107)

PMID:11848438 PMID:21873635

PMID:14702107

MGI:3027337

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

Cpb2

carboxypeptidase B2

involved_in

IMP
IBA

PMID:21873635

RGD
GO_Central

RGD:632532, RGD:13792537

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

coagulation factor XII

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

coagulation factor II

involved_in

(PMID:12855810)
GO_REF:0000107

PMID:12855810

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

fibrinogen alpha chain

involved_in

PMID:21873635
(PMID:16846481)

PMID:16846481 PMID:21873635

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

fibrinogen gamma chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:12855810)

PMID:12855810

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

histidine-rich glycoprotein

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

kallikrein B1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

similar to histidine-rich glycoprotein

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

Plau

plasminogen activator, urokinase

involved_in
acts_upstream_of_or_within

IBA
ISO
IEA

PMID:21873635
(MGI:1277054|PMID:9733098)
GO_REF:0000107

PMID:9733098 PMID:21873635

GO_REF:0000107 MGI:1277054, RGD:13792537

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

plasminogen

involved_in

GO_REF:0000104
(PMID:14688145), (PMID:17307854), (PMID:22025510)

PMID:14688145 PMID:17307854 PMID:22025510

GO_REF:0000104

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

Pros1

protein S

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

Serping1

serpin family G member 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa7

annexin A7

acts_upstream_of_or_within

MGI:2159006 (MGI:3046086|PMID:12925238)

PMID:12925238

MGI:3046086

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

glycoprotein Ib platelet subunit alpha

acts_upstream_of_or_within

MGI:2181691 (MGI:1860858|PMID:10706630)

PMID:10706630

MGI:1860858

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

Tspan32

tetraspanin 32

acts_upstream_of_or_within

MGI:2183564 (MGI:3804129|PMID:16720835)

PMID:16720835

MGI:3804129

NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445

Vwf

von Willebrand factor

involved_in
acts_upstream_of_or_within

(PMID:10887119)
MGI:2153009 (MGI:1276653|PMID:9689113)

PMID:9689113 PMID:10887119

MGI:1276653

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

Zfp385a

zinc finger protein 385A

acts_upstream_of_or_within

MGI:3510440 (MGI:3505817|PMID:11927637)

PMID:11927637

MGI:3505817

NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548

lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abcb1a

ATP binding cassette subfamily B member 1A

RGD

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

Abcb1b

ATP-binding cassette, subfamily B (MDR/TAP), member 1B

RGD

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

Alas2

5'-aminolevulinate synthase 2

RGD

PMID:18255020

RGD:4144779

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

Aprt

adenine phosphoribosyl transferase

RGD

PMID:2451510

RGD:1599204

NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431

Atp2b2

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1857876 (MGI:3510467|PMID:15302868)

PMID:15302868

MGI:3510467

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

Atp7a

ATPase copper transporting alpha

RGD

PMID:16741141

RGD:1599391

NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354

Atp7b

ATPase copper transporting beta

acts_upstream_of_or_within
involved_in

IEP
ISO
IEA

MGI:1856220|MGI:1856221 (MGI:49578|PMID:1588441), (MGI:55573|PMID:6863890)
GO_REF:0000107

PMID:1588441 PMID:6863890 PMID:16741141 PMID:28089327

GO_REF:0000107 MGI:49578 MGI:55573 MGI:71982, RGD:1599391, RGD:25671605

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

Bcat2

branched chain amino acid transaminase 2

PMID:11171603 PMID:11787736

RGD

RGD:62398, RGD:1599445

NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007

Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

RGD

NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861

Cav1

caveolin 1

involved_in
acts_upstream_of_negative_effect

GO_REF:0000107
MGI:2180364 (MGI:3703676|PMID:12388746)

PMID:12388746

GO_REF:0000107 MGI:3703676

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Ccnd1

cyclin D1

acts_upstream_of_or_within

MGI:2180640|MGI:99484 (MGI:1342136|PMID:10419681), (MGI:3045614|PMID:11747812)

PMID:10419681 PMID:11747812

MGI:1342136 MGI:3045614

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

Cdo1

cysteine dioxygenase type 1

RGD

PMID:6509133

RGD:2301364

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

Chuk

component of inhibitor of nuclear factor kappa B kinase complex

acts_upstream_of_or_within

MGI:3045616|MGI:88313 (MGI:3045614|PMID:11747812)

PMID:11747812

MGI:3045614

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

ceruloplasmin

RGD

PMID:28089327

RGD:25671605

NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075

Creb1

cAMP responsive element binding protein 1

acts_upstream_of_or_within

MGI:2176173|MGI:2181395 (MGI:3611103|PMID:16141355)

PMID:16141355

MGI:3611103

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

Csn2

casein beta

involved_in

(PMID:7979373)

PMID:7979373

NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817

Csn3

casein kappa

involved_in
acts_upstream_of_or_within

(PMID:7979373)
MGI:3640309 (MGI:3639646|PMID:16698927)
PMID:21873635

PMID:7979373 PMID:16698927 PMID:21873635

MGI:3639646, RGD:13792537

NCBI chr14:20,154,032...20,160,585
Ensembl chr14:20,154,032...20,160,587

Cyp27b1

cytochrome P450, family 27, subfamily b, polypeptide 1

RGD

PMID:8333523

RGD:2307320

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

Ddr1

discoidin domain receptor tyrosine kinase 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

Dhodh

dihydroorotate dehydrogenase (quinone)

RGD

NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654

Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

acts_upstream_of_or_within

MGI:3774276 (MGI:3815371|PMID:18852460)

PMID:18852460

MGI:3815371

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

Erbb4

erb-b2 receptor tyrosine kinase 4

involved_in

GO_REF:0000107
(MGI:5297795|PMID:10508857)
GO_REF:0000024
(PMID:15534001)

PMID:10508857 PMID:15534001

GO_REF:0000024 GO_REF:0000107 MGI:5297795

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

Foxb1

forkhead box B1

involved_in

GO_REF:0000024
(MGI:1931655|PMID:11170346)

PMID:11170346

GO_REF:0000024 MGI:1931655

NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781

GC, vitamin D binding protein

RGD

PMID:217634

RGD:2315536

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

Ghrhr

growth hormone releasing hormone receptor

acts_upstream_of_or_within

MGI:1856425 (MGI:49336|PMID:2980124), (MGI:54124|PMID:1270792)

PMID:1270792 PMID:2980124

MGI:49336 MGI:54124

NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776

Got2

glutamic-oxaloacetic transaminase 2

RGD

PMID:28798692

RGD:13504863

NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994

Gpat4

glycerol-3-phosphate acyltransferase 4

acts_upstream_of_or_within

MGI:3624276 (MGI:3623167|PMID:16449762)

PMID:16449762

MGI:3623167

NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901

Hif1a

hypoxia inducible factor 1 subunit alpha

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2386679 (MGI:2654263|PMID:12620994)

PMID:12620994

GO_REF:0000107 MGI:2654263

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

hexokinase 2

RGD

NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530

Kalrn

kalirin, RhoGEF kinase

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:5551305 (MGI:5551307|PMID:23116210)

PMID:23116210

GO_REF:0000107 MGI:5551307

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

Med1

mediator complex subunit 1

acts_upstream_of_or_within

MGI:3511276 (MGI:3576991|PMID:15647257)

PMID:15647257

MGI:3576991

NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299

Met

MET proto-oncogene, receptor tyrosine kinase

RGD

PMID:7628535

RGD:729001

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Mt-co2

mitochondrially encoded cytochrome c oxidase II

RGD

PMID:2557014

RGD:2302300

NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689

Metaxin 1

RGD

NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982

Muc4

mucin 4, cell surface associated

RGD

PMID:15499570

RGD:1582108

NCBI chr11:68,008,245...68,053,229

Ncoa1

nuclear receptor coactivator 1

RGD

PMID:15946693

RGD:5688303

NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664

Ncor1

nuclear receptor co-repressor 1

RGD

PMID:15946693

RGD:5688303

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

Ncor2

nuclear receptor co-repressor 2

RGD

PMID:15946693

RGD:5688303

NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319

Neurl1

neuralized E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

MGI:2153143 (MGI:2151733|PMID:11585928)

PMID:11585928

MGI:2151733

NCBI chr 1:246,066,642...246,152,890
Ensembl chr 1:246,067,100...246,152,903

Nme1

NME/NM23 nucleoside diphosphate kinase 1

acts_upstream_of_or_within

MGI:3628812 (MGI:3626054|PMID:12848338)

PMID:12848338

MGI:3626054

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

Oxt

oxytocin/neurophysin I prepropeptide

RGD

PMID:14624682

RGD:1579891

NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490

Pam

peptidylglycine alpha-amidating monooxygenase

RGD

PMID:16448835

RGD:2302418

NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965

Pmch

pro-melanin-concentrating hormone

RGD

PMID:14962080

RGD:1642485

NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250

Ppat

phosphoribosyl pyrophosphate amidotransferase

RGD

PMID:2451510

RGD:1599204

NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144

prolactin

RGD

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

Prlr

prolactin receptor

acts_upstream_of_or_within

MGI:1354910|MGI:1888377 (MGI:2137168|PMID:11445538), (MGI:2153620|PMID:11706048), (MGI:3623843|PMID:16469767)

PMID:11445538 PMID:11706048 PMID:16469767

MGI:2137168 MGI:2153620 MGI:3623843

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

Rplp0

ribosomal protein lateral stalk subunit P0

RGD

PMID:20863866

RGD:11039458

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

Serpinc1

serpin family C member 1

RGD

PMID:22776112

RGD:11035275

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

Slc29a1

solute carrier family 29 member 1

RGD

NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203

Slc29a2

solute carrier family 29 member 2

RGD

NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171

Slc30a4

solute carrier family 30 member 4

RGD

PMID:14608047

RGD:2299951

NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306

Slc6a3

solute carrier family 6 member 3

acts_upstream_of_or_within

MGI:2386303 (MGI:894559|PMID:9247269)

PMID:9247269

MGI:894559

NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413

Socs2

suppressor of cytokine signaling 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:97763 (MGI:2137168|PMID:11445538)

PMID:11445538

GO_REF:0000107 MGI:2137168

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

IEP
ISO

MGI:1857249|MGI:2181607 (MGI:2153620|PMID:11706048), (MGI:2181561|PMID:9630227)

PMID:9630227 PMID:11706048 PMID:8584036

MGI:2153620 MGI:2181561, RGD:730121

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat5b

signal transducer and activator of transcription 5B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2181609 (MGI:2153620|PMID:11706048), (MGI:2181561|PMID:9630227)

PMID:9630227 PMID:11706048

GO_REF:0000107 MGI:2153620 MGI:2181561

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Umps

uridine monophosphate synthetase

RGD

NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903

Uprt

uracil phosphoribosyltransferase homolog

RGD

NCBI chr X:69,516,573...69,546,811
Ensembl chr X:69,516,738...69,546,797

Usf2

upstream transcription factor 2, c-fos interacting

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2181680 (MGI:2679398|PMID:12907752)

PMID:12907752

GO_REF:0000107 MGI:2679398

NCBI chr 1:86,174,703...86,185,942
Ensembl chr 1:86,174,703...86,185,617

Vdr

vitamin D receptor

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2183404 (MGI:3051725|PMID:15178742)

PMID:15178742

GO_REF:0000107 MGI:3051725

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

Vegfa

vascular endothelial growth factor A

acts_upstream_of_or_within

MGI:1926815|MGI:1931048 (MGI:3789854|PMID:17625068)

PMID:17625068

MGI:3789854

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Xdh

xanthine dehydrogenase

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2448161 (MGI:2447927|PMID:12502743)

PMID:12502743

GO_REF:0000107 MGI:2447927

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

Zbtb7b

zinc finger and BTB domain containing 7B

involved_in

(MGI:6120228|PMID:29420538)

PMID:29420538

MGI:6120228

NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236

milk ejection reflex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gja1

gap junction protein, alpha 1

acts_upstream_of_or_within

MGI:2682016 (MGI:4452310|PMID:20089884)

PMID:20089884

MGI:4452310

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agr2

anterior gradient 2, protein disulphide isomerase family member

involved_in

(MGI:3844381|PMID:19359471)

PMID:19359471

MGI:3844381

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

MGI:3785162 (MGI:6100817|PMID:27959908)

PMID:27959908

MGI:6100817

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

Scnn1b

sodium channel epithelial 1 subunit beta

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:6478086|PMID:22419116)

PMID:22419116

GO_REF:0000107 MGI:6478086

NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451

Traf3ip2

Traf3 interacting protein 2

involved_in

MGI:3831153 (MGI:3830744|PMID:19155511)

PMID:19155511

MGI:3830744

NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667

Vamp2

vesicle-associated membrane protein 2

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809

Vamp3

vesicle-associated membrane protein 3

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751

Vamp8

vesicle-associated membrane protein 8

involved_in

IEA
ISO
IBA

GO_REF:0000107
(MGI:5484853|PMID:22144578)
PMID:21873635
(PMID:22144578)

PMID:22144578 PMID:21873635

GO_REF:0000107 MGI:5484853, RGD:13792537

NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897

multicellular organismal water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1

involved_in

(PMID:17645239)

PMID:17645239

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Aqp4

aquaporin 4

involved_in

(PMID:16814974), (PMID:17645239)
GO_REF:0000107

PMID:16814974 PMID:17645239

GO_REF:0000107

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

arginine vasopressin

RGD

NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425

Bpifa1

BPI fold containing family A, member 1

involved_in

GO_REF:0000024
(PMID:24124190)

PMID:24124190

GO_REF:0000024

NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552

Cftr

CF transmembrane conductance regulator

involved_in

GO_REF:0000107
(PMID:19621064)
GO_REF:0000024

PMID:19621064

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

Ext1

exostosin glycosyltransferase 1

acts_upstream_of_or_within

MGI:108050 (MGI:6343289|PMID:31365577)

PMID:31365577

MGI:6343289

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

Ext2

exostosin glycosyltransferase 2

acts_upstream_of_or_within

MGI:894663 (MGI:6343289|PMID:31365577)

PMID:31365577

MGI:6343289

NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059

Nppa

natriuretic peptide A

RGD

PMID:11751587

RGD:70434

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

Scnn1a

sodium channel epithelial 1 subunit alpha

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:24124190)

PMID:24124190

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181

Scnn1b

sodium channel epithelial 1 subunit beta

involved_in
acts_upstream_of_or_within

GO_REF:0000024
GO_REF:0000107
(MGI:3815289|PMID:17430990), (MGI:6478095|PMID:28567665)
(PMID:24124190)

PMID:17430990 PMID:24124190 PMID:28567665

GO_REF:0000024 GO_REF:0000107 MGI:3815289 MGI:6478095

NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451

Scnn1g

sodium channel epithelial 1 subunit gamma

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:24124190)

PMID:24124190

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816

Trpv4

transient receptor potential cation channel, subfamily V, member 4

involved_in

ISO
IMP

(PMID:23136043)

PMID:23136043 PMID:23136043

RGD:10400856

NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517

negative regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adtrp

androgen-dependent TFPI-regulating protein

involved_in

(PMID:21868574)
GO_REF:0000107

PMID:21868574

GO_REF:0000107

NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826

annexin A5

RGD

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

Apoe

apolipoprotein E

involved_in

(PMID:8995232)

PMID:8995232

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

apolipoprotein H

involved_in

GO_REF:0000107
(PMID:4052628)

PMID:4052628

GO_REF:0000107

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

Cd34

CD34 molecule

involved_in

(PMID:17505307)
GO_REF:0000024

PMID:17505307

GO_REF:0000024

NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832

Kng1

kininogen 1

involved_in

IBA
IEA

PMID:21873635
GO_REF:0000107

Ensembl

GO_REF:0000107, RGD:13792537

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

Kng2

kininogen 2

involved_in

(PMID:11970955)
PMID:21873635

PMID:11970955 PMID:21873635

NCBI chr11:77,913,876...77,936,247

Kng2l1

kininogen 2-like 1

involved_in

PMID:21873635

GO_Central

NCBI chr11:77,978,795...78,002,976

Proc

protein C, inactivator of coagulation factors Va and VIIIa

involved_in
acts_upstream_of_or_within

IDA
ISO
IBA

(PMID:25651845)
MGI:2183063 (MGI:1261704|PMID:9616155), (MGI:1306904|PMID:9788960)
PMID:21873635

PMID:9616155 PMID:9788960 PMID:25651845 PMID:1440533 PMID:21873635

MGI:1261704 MGI:1306904, RGD:11100042, RGD:13792537

NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133

serpin family E member 2

involved_in

IDA
ISO

PMID:17379830
(PMID:17379830)

PMID:17379830 PMID:17379830

RGD:8553298

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

Tfpi

tissue factor pathway inhibitor

involved_in

(PMID:21868574)

PMID:21868574

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

Thbd

thrombomodulin

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

tetraspanin 8

RGD

NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356

negative regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:14726399)
GO_REF:0000107

PMID:14726399

GO_REF:0000107

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

carboxypeptidase B2

RGD

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

histidine-rich glycoprotein

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:3789962 (MGI:3789419|PMID:15869579)

PMID:15869579 PMID:21873635

MGI:3789419, RGD:13792537

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

similar to histidine-rich glycoprotein

involved_in

PMID:21873635

GO_Central

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

plasminogen

involved_in

(PMID:14726399)

PMID:14726399

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

Serpine1

serpin family E member 1

involved_in

(PMID:2503541)
GO_REF:0000107

PMID:2503541

GO_REF:0000107

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

Serpinf2

serpin family F member 2

involved_in

IMP
ISO

(PMID:134998)

PMID:134998 PMID:6506034

RGD:1625541

NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243

Thbs1

thrombospondin 1

involved_in

(PMID:6438154)

PMID:6438154

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

negative regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor II (thrombin) receptor

involved_in

PMID:12644441

UniProt

PMID:12644441

RGD:1582293

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

Gja5

gap junction protein, alpha 5

RGD

PMID:17928514

RGD:7207472

NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952

Ptpro

protein tyrosine phosphatase, receptor type, O

involved_in

PMID:19403647

UniProt

PMID:19403647

RGD:8554129

NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771

urotensin 2

RGD

NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237

urotensin 2 receptor

RGD

NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252

negative regulation of glomerular filtration by angiotensin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cyba

cytochrome b-245 alpha chain

RGD

PMID:17220186

RGD:2317863

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

negative regulation of hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Comp

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2180787 (MGI:5694900|PMID:26045608)

PMID:26045608

GO_REF:0000107 MGI:5694900

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

negative regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ada

adenosine deaminase

acts_upstream_of_or_within

MGI:104847|MGI:1857117|MGI:2683027|MGI:99401 (MGI:3051181|PMID:15240734), (MGI:3525377|PMID:15630442)

PMID:15240734 PMID:15630442

MGI:3051181 MGI:3525377

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

Adora1

adenosine A1 receptor

acts_upstream_of_or_within

MGI:87916 (MGI:3525377|PMID:15630442)

PMID:15630442

MGI:3525377

NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801

negative regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Madd

MAP-kinase activating death domain

RGD

PMID:23702376

RGD:9588639

NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701

negative regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nr1h3

nuclear receptor subfamily 1, group H, member 3

involved_in

GO_REF:0000107
(MGI:3822255|PMID:18806227)

PMID:18806227

GO_REF:0000107 MGI:3822255

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

Stk39

serine threonine kinase 39

involved_in

(MGI:5002793|PMID:21317537)

NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060

Wnk1

WNK lysine deficient protein kinase 1

acts_upstream_of_or_within

(MGI:5002793|PMID:21317537)

NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905

Wnk3

WNK lysine deficient protein kinase 3

involved_in

(MGI:5002793|PMID:21317537)

NCBI chr X:20,156,260...20,299,252
Ensembl chr X:20,157,041...20,296,821

Wnk4

WNK lysine deficient protein kinase 4

acts_upstream_of_or_within

(MGI:5002793|PMID:21317537)

NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829

negative regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apoe

apolipoprotein E

involved_in

GO_REF:0000107
(PMID:8995232)

PMID:8995232

GO_REF:0000107

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

C1qtnf1

C1q and TNF related 1

involved_in

(PMID:16195328)

PMID:16195328

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

glycoprotein V (platelet)

acts_upstream_of_or_within

MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305)

PMID:10557321 PMID:11435305

MGI:1347746 MGI:2137180

NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705

Pdgfa

platelet derived growth factor subunit A

involved_in

ISO
IEA
ISS

(PMID:2538439)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:2538439

GO_REF:0000024 GO_REF:0000107

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

Pdgfb

platelet derived growth factor subunit B

involved_in

ISO
ISS
IEA

(PMID:2538439)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:2538439

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Pdgfra

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:8188664)

PMID:8188664

GO_REF:0000024 GO_REF:0000107

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

serpin family E member 2

acts_upstream_of_or_within

MGI:2387774 (MGI:4418017|PMID:19855083)

PMID:19855083

MGI:4418017

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

negative regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abat

4-aminobutyrate aminotransferase

RGD

PMID:12742000

RGD:10047059

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

Adamts18

ADAM metallopeptidase with thrombospondin type 1 motif, 18

acts_upstream_of_or_within

(MGI:3848389|PMID:19218546)
(PMID:19218546)

PMID:19218546

MGI:3848389

NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781

adrenoceptor beta 2

RGD

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

Alox12

arachidonate 12-lipoxygenase, 12S type

involved_in

GO_REF:0000024
(MGI:1202206|PMID:9501222)

PMID:9501222

GO_REF:0000024 MGI:1202206

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

C1qtnf1

C1q and TNF related 1

involved_in

(PMID:16195328)
GO_REF:0000107

PMID:16195328

GO_REF:0000107

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

Cd9

CD9 molecule

involved_in

GO_REF:0000024
(PMID:18541721)

PMID:18541721

GO_REF:0000024

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

Ceacam1

CEA cell adhesion molecule 1

involved_in

GO_REF:0000024
(MGI:3835235|PMID:19008452)

PMID:19008452

GO_REF:0000024 MGI:3835235

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

fibrinogen gamma chain

RGD

PMID:22985603

RGD:11352706

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Prkcd

protein kinase C, delta

involved_in

GO_REF:0000024
(MGI:3813784|PMID:16940418)
GO_REF:0000107

PMID:16940418

GO_REF:0000024 GO_REF:0000107 MGI:3813784

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Prkg1

protein kinase cGMP-dependent 1

involved_in

(PMID:16990611)

PMID:16990611

NCBI chr 1:228,409,883...229,638,794

Ptger3

prostaglandin E receptor 3

RGD

PMID:20303752

RGD:10043327

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

serpin family E member 2

involved_in

GO_REF:0000107
(MGI:4418017|PMID:19855083)

PMID:19855083

GO_REF:0000107 MGI:4418017

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

Sh2b3

SH2B adaptor protein 3

involved_in

GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)

PMID:27430239

GO_REF:0000107 MGI:5905608

NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616

Ubash3b

ubiquitin associated and SH3 domain containing, B

acts_upstream_of_or_within

(MGI:4838721|PMID:20585042)

PMID:20585042

MGI:4838721

NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201

negative regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Neurog1

neurogenin 1

involved_in

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)

PMID:23419067

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Tifab

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

PMID:23419067

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

negative regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcy6

adenylate cyclase 6

involved_in

GO_REF:0000024
(MGI:4457984|PMID:20466003)

PMID:20466003

GO_REF:0000024 MGI:4457984

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

adrenoceptor beta 1

RGD

NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259

adrenoceptor beta 2

RGD

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

Avpr2

arginine vasopressin receptor 2

RGD

PMID:18057218

RGD:2304118

NCBI chr X:151,633,501...151,636,000
Ensembl chr X:151,633,522...151,635,989

Mllt6

MLLT6, PHD finger containing

acts_upstream_of_or_within

MGI:3856248 (MGI:5644399|PMID:21546577)

PMID:21546577

MGI:5644399

NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073

Oxt

oxytocin/neurophysin I prepropeptide

RGD

PMID:18057218

RGD:2304118

NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490

Slc4a1

solute carrier family 4 member 1 (Diego blood group)

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857140 (MGI:3843596|PMID:17409310)

PMID:17409310

GO_REF:0000107 MGI:3843596

NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117

Slc5a2

solute carrier family 5 member 2

RGD

PMID:29790389

RGD:13673897

NCBI chr 1:182,847,185...182,853,309
Ensembl chr 1:182,847,106...182,853,306

urotensin 2

RGD

NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237

urotensin 2 receptor

RGD

NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252

pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1

involved_in

(PMID:12801959)

PMID:12801959

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Aqp5

aquaporin 5

involved_in

(PMID:12801959)

PMID:12801959

NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209

Cckar

cholecystokinin A receptor

RGD

PMID:16327284

RGD:2313374

NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747

Cel

carboxyl ester lipase

involved_in

(PMID:1854805)
GO_REF:0000107

PMID:1854805

GO_REF:0000107

NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035

Copa

COPI coat complex subunit alpha

acts_upstream_of_or_within

(PMID:1429581)

PMID:1429581

NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874

Dbi

diazepam binding inhibitor, acyl-CoA binding protein

RGD

PMID:10675361

RGD:2316282

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

Npr3

natriuretic peptide receptor 3

RGD

PMID:12829435

RGD:1581460

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

urocortin

RGD

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

phosphatidylserine exposure on blood platelet

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ano6

anoctamin 6

involved_in

(PMID:21107324)

PMID:21107324

NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589

platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Actn1

actinin, alpha 1

NOT|involved_in

(PMID:24069336)

PMID:24069336

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

Adra2a

adrenoceptor alpha 2A

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Adra2b

adrenoceptor alpha 2B

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

Adra2c

adrenoceptor alpha 2C

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846

Axl

Axl receptor tyrosine kinase

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:2387750 (MGI:3528131|PMID:15650770)

PMID:15650770 PMID:21873635

MGI:3528131, RGD:13792537

NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265

Bloc1s3

biogenesis of lysosomal organelles complex-1, subunit 3

involved_in

(PMID:16385460)

PMID:16385460

NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505

C1galt1c1

C1GALT1-specific chaperone 1

acts_upstream_of_or_within

MGI:4459539 (MGI:5448092|PMID:22988088)

PMID:22988088

MGI:5448092

NCBI chr X:117,378,123...117,382,620
Ensembl chr X:117,375,525...117,382,787

Cd40lg

CD40 ligand

involved_in

GO_REF:0000104
(PMID:9468137)
GO_REF:0000024

PMID:9468137

GO_REF:0000024 GO_REF:0000104

NCBI chr X:135,127,119...135,138,302
Ensembl chr X:135,126,969...135,138,306

Ctsg

cathepsin G

involved_in

(PMID:10702240)

PMID:10702240

NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353

Cx3cl1

C-X3-C motif chemokine ligand 1

RGD

PMID:12969973

RGD:4891996

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

Entpd1

ectonucleoside triphosphate diphosphohydrolase 1

acts_upstream_of_or_within

(MGI:2178511|PMID:11929769)

PMID:11929769

MGI:2178511

NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317

Entpd2

ectonucleoside triphosphate diphosphohydrolase 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:2178511|PMID:11929769)

PMID:11929769

GO_REF:0000107 MGI:2178511

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

coagulation factor II

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000107
(MGI:3709713|PMID:17380206)
PMID:21873635
(PMID:9038223)

PMID:9038223 PMID:17380206 PMID:21873635

GO_REF:0000107 MGI:3709713, RGD:13792537

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

coagulation factor II (thrombin) receptor

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:9038223)

PMID:9038223

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

F2rl3

F2R like thrombin or trypsin receptor 3

involved_in

(PMID:10702240)

PMID:10702240

NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472

fibrinogen alpha chain

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

Fzd6

frizzled class receptor 6

acts_upstream_of_or_within

MGI:3050103 (MGI:4398768|PMID:19901330)

PMID:19901330

MGI:4398768

NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776

Gna13

G protein subunit alpha 13

acts_upstream_of_or_within

MGI:2151775 (MGI:3583058|PMID:14528298)

PMID:14528298

MGI:3583058

NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774

histidine-rich glycoprotein

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:19903770)

PMID:19903770

GO_REF:0000024 GO_REF:0000107

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

Itgb3

integrin subunit beta 3

involved_in

(PMID:15466936)

PMID:15466936

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

similar to histidine-rich glycoprotein

involved_in

ISS
IEA

GO_REF:0000024
GO_REF:0000107

UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

Mertk

MER proto-oncogene, tyrosine kinase

acts_upstream_of_or_within

MGI:2387765 (MGI:3528131|PMID:15650770)

PMID:15650770

MGI:3528131

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

P2rx1

purinergic receptor P2X 1

acts_upstream_of_or_within

MGI:2181608 (MGI:2671726|PMID:12913094)

PMID:12913094

MGI:2671726

NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623

P2ry1

purinergic receptor P2Y1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457

P2ry12

purinergic receptor P2Y12

acts_upstream_of_or_within

MGI:2445936 (MGI:2136079|PMID:11413167)

PMID:11413167

MGI:2136079

NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361

Pdia6

protein disulfide isomerase family A, member 6

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613

Pf4

platelet factor 4

involved_in

(PMID:11685038)
GO_REF:0000024

PMID:11685038

GO_REF:0000024

NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365

Pik3cb

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3577829|PMID:15834429)

PMID:15834429

GO_REF:0000107 MGI:3577829

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

Ppbp

pro-platelet basic protein

RGD

PMID:11785982

RGD:70252

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

Ppia

peptidylprolyl isomerase A

involved_in

GO_REF:0000024
(MGI:6450355|PMID:24429998)

PMID:24429998

GO_REF:0000024 MGI:6450355

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

Ppial4d

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284

Rap2b

RAP2B, member of RAS oncogene family

involved_in

(PMID:18582561)

PMID:18582561

NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069

Srf

serum response factor

acts_upstream_of_or_within

MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922)

PMID:20525922

MGI:4834086

NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733

Treml1

triggering receptor expressed on myeloid cells-like 1

involved_in
acts_upstream_of_or_within

(PMID:15128762)
(PMID:15100151)
PMID:21873635

PMID:15100151 PMID:15128762 PMID:21873635

NCBI chr 9:12,635,584...12,642,929
Ensembl chr 9:12,635,590...12,642,347

Tyro3

TYRO3 protein tyrosine kinase

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2387762 (MGI:3528131|PMID:15650770)

PMID:15650770

GO_REF:0000024 MGI:3528131

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

Ubash3b

ubiquitin associated and SH3 domain containing, B

acts_upstream_of_or_within

MGI:2670555 (MGI:5811934|PMID:27609517)

PMID:27609517

MGI:5811934

NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201

Vwf

von Willebrand factor

involved_in
NOT|acts_upstream_of_or_within

IMP
IEA
ISO

GO_REF:0000104
MGI:2153009 (MGI:3709713|PMID:17380206)
MGI:2153009 (MGI:1861538|PMID:10930441), (MGI:4888158|PMID:21037087)
(PMID:8565074)
GO_REF:0000107

PMID:8565074 PMID:10930441 PMID:17380206 PMID:21037087 PMID:10709908 More...

GO_REF:0000104 GO_REF:0000107 MGI:1861538 MGI:3709713 MGI:4888158, RGD:1599012, RGD:1599016

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

Wnt3a

Wnt family member 3A

acts_upstream_of_or_within

(MGI:4398768|PMID:19901330)

PMID:19901330

MGI:4398768

NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324

platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Actb

actin, beta

involved_in

(PMID:23382103)

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

Actg1

actin, gamma 1

involved_in

(PMID:23382103)

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232

Actn1

actinin, alpha 1

NOT|involved_in

(PMID:23434115)

PMID:23434115

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

Bloc1s4

biogenesis of lysosomal organelles complex 1 subunit 4

acts_upstream_of_or_within

MGI:2449643 (MGI:1354542|PMID:11110696)

PMID:11110696

MGI:1354542

NCBI chr14:74,043,025...74,044,325
Ensembl chr14:74,043,015...74,044,531

Cfh

complement factor H

acts_upstream_of_or_within

(MGI:5883383|PMID:28057640)

PMID:28057640

MGI:5883383

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

Clic1

chloride intracellular channel 1

involved_in

(PMID:23382103)

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

Comp

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2180787 (MGI:5694900|PMID:26045608)

PMID:26045608

GO_REF:0000107 MGI:5694900

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

Csrp1

cysteine and glycine-rich protein 1

involved_in

(PMID:23382103)

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

Fermt3

FERM domain containing kindlin 3

involved_in

PMID:21873635
(MGI:3783912|PMID:18278053)

PMID:18278053 PMID:21873635

MGI:3783912, RGD:13792537

NCBI chr 1:204,189,483...204,207,683
Ensembl chr 1:204,189,484...204,207,587

fibrinogen alpha chain

involved_in

(PMID:6281794)
PMID:21873635

PMID:6281794 PMID:21873635

NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

(PMID:6281794)
PMID:21873635

PMID:6281794 PMID:21873635

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

fibrinogen gamma chain

involved_in

(PMID:6281794)
PMID:21873635

PMID:6281794 PMID:21873635

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Fibp

FGF1 intracellular binding protein

involved_in

(PMID:23382103)

NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399

Flna

filamin A

involved_in

(PMID:23382103)

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

Fn1

fibronectin 1

involved_in

PMID:21873635

GO_Central

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

Gata1

GATA binding protein 1

involved_in

(PMID:15701726)
(MGI:3580921|PMID:15701726)

PMID:15701726

MGI:3580921

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

Gnas

GNAS complex locus

involved_in

(PMID:12719376)

PMID:12719376

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

PMID:10727447 PMID:21873635

glycoprotein Ib platelet subunit alpha

involved_in

IMP
IBA

PMID:21873635

RGD
GO_Central

RGD:10450868, RGD:13792537

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

Hbb

hemoglobin subunit beta

involved_in

(PMID:23382103)

NCBI chr 1:158,250,421...158,251,832

Hspb1

heat shock protein family B (small) member 1

involved_in

(PMID:23382103)

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

Ilk

integrin-linked kinase

involved_in

(PMID:23382103)

NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140

Itga2b

integrin subunit alpha 2b

PMID:15466936 PMID:17924279

RGD

PMID:17924279

RGD:2316357

NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168

Itgb3

integrin subunit beta 3

involved_in

IMP
ISO
IEA

(PMID:15466936)
GO_REF:0000002

RGD
InterPro

GO_REF:0000002, RGD:2316357

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

Metap1

methionyl aminopeptidase 1

involved_in

(PMID:23382103)

NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434

Mpl

MPL proto-oncogene, thrombopoietin receptor

RGD

PMID:15670044

RGD:10448997

NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797

Myh9

myosin, heavy chain 9

involved_in

(PMID:23382103)

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

Myl12a

myosin light chain 12A

involved_in

(PMID:23382103)

NCBI chr 9:110,891,970...110,899,655
Ensembl chr 9:110,873,959...110,916,580

Myl9

myosin light chain 9

involved_in

(PMID:23382103)

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

P2ry12

purinergic receptor P2Y12

involved_in

IMP
ISO

(PMID:12578987)

PMID:12578987 PMID:19028049

RGD:6480528

NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361

Pdgfra

platelet derived growth factor receptor alpha

involved_in

ISO
IEA
ISS

(PMID:8188664)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:8188664

GO_REF:0000024 GO_REF:0000107

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Pdia6

protein disulfide isomerase family A, member 6

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613

Pear1

platelet endothelial aggregation receptor 1

involved_in

(MGI:5817200|PMID:27614188)

PMID:27614188

MGI:5817200

NCBI chr 2:173,206,298...173,234,106
Ensembl chr 2:173,207,664...173,227,440

Pip5k1c

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

acts_upstream_of_or_within

MGI:2385922|MGI:5496877 (MGI:5488558|PMID:23372168)

PMID:23372168

MGI:5488558

NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988

Plek

pleckstrin

involved_in

(MGI:3844782|PMID:19190246)

PMID:19190246

MGI:3844782

NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131

Ppia

peptidylprolyl isomerase A

involved_in

GO_REF:0000024
(MGI:6450355|PMID:24429998)

PMID:24429998

GO_REF:0000024 MGI:6450355

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

Ppial4d

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3719625 (MGI:5494903|PMID:23509158)

PMID:23509158

GO_REF:0000107 MGI:5494903

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Rap2b

RAP2B, member of RAS oncogene family

involved_in

(PMID:18582561)

PMID:18582561

NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069

Slc7a11

solute carrier family 7 member 11

acts_upstream_of_or_within

MGI:1857061 (MGI:79102|PMID:8699821)

PMID:8699821

MGI:79102

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

Stxbp1

syntaxin binding protein 1

involved_in

(PMID:12773094)

PMID:12773094

NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369

Stxbp3

syntaxin binding protein 3

involved_in

(PMID:12773094)

PMID:12773094

NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671

Tln1

talin 1

involved_in

(PMID:23382103)

NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900

Tspan32

tetraspanin 32

acts_upstream_of_or_within

MGI:2183564 (MGI:3804129|PMID:16720835)

PMID:16720835

MGI:3804129

NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445

Tyro3

TYRO3 protein tyrosine kinase

involved_in

IEA
ISO
ISS
IBA

GO_REF:0000107
(MGI:5306558|PMID:20546121)
GO_REF:0000024
PMID:21873635

PMID:20546121 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:5306558, RGD:13792537

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

Ubash3a

ubiquitin associated and SH3 domain containing, A

NOT|acts_upstream_of_or_within

MGI:3051962 (MGI:5811934|PMID:27609517)

PMID:27609517

MGI:5811934

NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224

Ubash3b

ubiquitin associated and SH3 domain containing, B

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:2670555 (MGI:5811934|PMID:27609517)

PMID:27609517 PMID:21873635

MGI:5811934, RGD:13792537

NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201

Vcl

vinculin

involved_in

(PMID:23382103)

NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606

Wnt3a

Wnt family member 3A

acts_upstream_of_or_within

(MGI:4398768|PMID:19901330)

PMID:19901330

MGI:4398768

NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324

positive regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd36

CD36 molecule

involved_in

(MGI:4850200|PMID:20978343)
GO_REF:0000107

PMID:20978343

GO_REF:0000107 MGI:4850200

NCBI chr 4:17,317,343...17,410,084

Dmtn

dematin actin binding protein

involved_in

(MGI:5465511|PMID:23060452)

PMID:23060452

MGI:5465511

NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601

Emilin2

elastin microfibril interfacer 2

involved_in

(MGI:5698770|PMID:25658937)

PMID:25658937

MGI:5698770

NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352

Enpp4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

(PMID:22995898)

PMID:22995898

NCBI chr 9:16,888,923...16,898,860
Ensembl chr 9:16,887,739...16,898,860

coagulation factor XII

involved_in

GO_REF:0000107
(PMID:6793628)

PMID:6793628

GO_REF:0000107

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

coagulation factor II

involved_in

IMP
IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(PMID:9038223)

PMID:9038223 PMID:20664909 PMID:21873635

GO_REF:0000107, RGD:10449431, RGD:13792537

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

coagulation factor II (thrombin) receptor

involved_in
acts_upstream_of_or_within

IEA
ISO
ISS
IBA

GO_REF:0000107
MGI:3038377 (MGI:3784647|PMID:18305483)
GO_REF:0000024
(PMID:9038223)
PMID:21873635

PMID:9038223 PMID:18305483 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:3784647, RGD:13792537

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

coagulation factor VII

RGD

PMID:12757778

RGD:2312295

NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610

Hpse

heparanase

involved_in

(PMID:20634491)
GO_REF:0000107

PMID:20634491

GO_REF:0000107

NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010

Nfe2l2

NFE2 like bZIP transcription factor 2

involved_in

(MGI:4850200|PMID:20978343)

PMID:20978343

MGI:4850200

NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737

Prdx2

peroxiredoxin 2

involved_in

GO_REF:0000107
(MGI:4850200|PMID:20978343)

PMID:20978343

GO_REF:0000107 MGI:4850200

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

RGD1565355

similar to fatty acid translocase/CD36

involved_in

GO_REF:0000107

Ensembl

GO_REF:0000107

NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903

S100a9

S100 calcium binding protein A9

involved_in

(MGI:5582990|PMID:24691441)

PMID:24691441

MGI:5582990

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

Serpine1

serpin family E member 1

involved_in

(PMID:9207454)

PMID:9207454

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

St3gal4

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

involved_in

GO_REF:0000024
(MGI:2447421|PMID:12097641)

PMID:12097641

GO_REF:0000024 MGI:2447421

NCBI chr 8:33,415,666...33,465,365
Ensembl chr 8:33,415,671...33,524,389

Tbxa2r

thromboxane A2 receptor

RGD

PMID:7848332

RGD:11059887

NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176

Thbs1

thrombospondin 1

involved_in

(PMID:3997886)

PMID:3997886

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

positive regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor XI

involved_in

(PMID:89876)

PMID:89876

NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437

coagulation factor XII

involved_in

GO_REF:0000107
(PMID:89876)

PMID:89876

GO_REF:0000107

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

kallikrein B1

involved_in

(PMID:89876)
GO_REF:0000107

PMID:89876

GO_REF:0000107

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

plasminogen

involved_in

(PMID:26667841), (PMID:6438154)

PMID:6438154 PMID:26667841

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

positive regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2rl1

F2R like trypsin receptor 1

involved_in

PMID:12644441

UniProt

PMID:12644441

RGD:1582293

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Gas6

growth arrest specific 6

involved_in

PMID:18374201

UniProt

PMID:18374201

RGD:8554638

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

Gja1

gap junction protein, alpha 1

RGD

PMID:18046320

RGD:7207467

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

Pdgfb

platelet derived growth factor subunit B

involved_in

GO_REF:0000024
(MGI:3039044|PMID:15084468)

PMID:15084468

GO_REF:0000024 MGI:3039044

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

positive regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07027730.1

involved_in

PMID:21873635

GO_Central

Comt

catechol-O-methyltransferase

RGD:11557979

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

LOC103690150

prolactin-3D1

involved_in

PMID:21873635

GO_Central

LOC684107

similar to placental prolactin-like protein O

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,974,838...36,982,243
Ensembl chr17:36,974,838...36,982,212

Prl

prolactin

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

Prl2a1

Prolactin family 2, subfamily a, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,931,000...36,937,092
Ensembl chr17:36,931,001...36,937,092

Prl2b1

Prolactin family 2, subfamily b, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,591,159...37,598,186
Ensembl chr17:37,591,197...37,598,183

Prl2c1

Prolactin family 2, subfamily c, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,881,099...36,889,419
Ensembl chr17:36,881,099...36,889,419

Prl3a1

Prolactin family 3, subfamily a, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,693,595...37,711,959
Ensembl chr17:37,693,593...37,711,959

Prl3b1

Prolactin family 3, subfamily b, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,743,681...37,749,340
Ensembl chr17:37,743,684...37,749,340

Prl3c1

Prolactin family 3, subfamily c, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,784,674...37,790,468
Ensembl chr17:37,784,801...37,790,421

Prl3d1

Prolactin family 3, subfamily d, member 1

involved_in

PMID:21873635

GO_Central

Prl3d2

Prolactin family 3, subfamily d, member 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,823,027...37,829,506
Ensembl chr17:37,823,027...37,829,052

Prl3d4

prolactin family 3, subfamily d, member 4

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667

Prl4a1

prolactin family 4, subfamily a, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,741,010...36,748,952
Ensembl chr17:36,741,041...36,748,987

Prl5a1

prolactin family 5, subfamily a, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,585,754...36,593,192
Ensembl chr17:36,516,579...36,593,192

Prl5a2

prolactin family 5, subfamily a, member 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,452,712...36,459,054
Ensembl chr17:36,452,718...36,459,054

Prl6a1

prolactin family 6, subfamily a, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,675,239...37,680,083
Ensembl chr17:37,675,243...37,680,113

Prl7a3

prolactin family 7, subfamily a, member 3

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,086,164...37,099,039
Ensembl chr17:37,086,136...37,099,037

Prl7a4

prolactin family 7, subfamily a, member 4

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,148,524...37,157,580
Ensembl chr17:37,148,520...37,157,579

Prl7b1

prolactin family 7, subfamily b, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,202,058...37,214,739
Ensembl chr17:37,206,547...37,214,723

Prl7d1

prolactin family 7, subfamily d, member 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:36,982,746...37,053,328
Ensembl chr17:37,046,834...37,053,691

Prl8a2

prolactin family 8, subfamily a, member 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,613,263...37,622,288
Ensembl chr17:37,613,267...37,622,288

Prl8a3

prolactin family 8, subfamily a, member 3

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,508,328...37,514,832

Prl8a4

prolactin family 8, subfamily a, member 4

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,429,960...37,436,053
Ensembl chr17:37,429,960...37,436,053

Prl8a5

prolactin family 8, subfamily a, member 5

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,465,641...37,471,852

Prl8a7

prolactin family 8, subfamily a, member 7

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,558,822...37,564,724
Ensembl chr17:37,558,883...37,564,718

Prl8a9

prolactin family 8, subfamily a, member 9

involved_in

PMID:21873635

GO_Central

NCBI chr17:37,295,054...37,300,862
Ensembl chr17:37,295,054...37,300,859

Xbp1

X-box binding protein 1

involved_in

GO_REF:0000024
(MGI:5496939|PMID:23623498)

PMID:23623498

GO_REF:0000024 MGI:5496939

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

positive regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora3

adenosine A3 receptor

acts_upstream_of_or_within

MGI:2155986|MGI:87916 (MGI:3051181|PMID:15240734)

arachidonate 12-lipoxygenase, 12R type

involved_in

GO_REF:0000024
(PMID:22441738)
GO_REF:0000107

PMID:22441738

GO_REF:0000024 GO_REF:0000107

NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938

Atg5

autophagy related 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3663625 (MGI:5548044|PMID:24185898)

GO_REF:0000107 MGI:5548044

NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209

Atg7

autophagy related 7

acts_upstream_of_or_within

MGI:3587769 (MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

Cyba

cytochrome b-245 alpha chain

acts_upstream_of_or_within

MGI:3526726 (MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

Egfr

epidermal growth factor receptor

RGD

PMID:29183867

RGD:38676259

NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382

Map1lc3b

microtubule-associated protein 1 light chain 3 beta

acts_upstream_of_or_within

MGI:3774111 (MGI:5548044|PMID:24185898)

MGI:5548044

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

P2ry2

purinergic receptor P2Y2

involved_in
acts_upstream_of_or_within

GO_REF:0000002
MGI:3613160 (MGI:3833522|PMID:17728398)

InterPro
RGD

PMID:17728398

GO_REF:0000002 MGI:3833522

NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632

Prkce

protein kinase C, epsilon

acts_upstream_of_or_within
involved_in

MGI:2152043 (MGI:3833522|PMID:17728398)
GO_REF:0000107

PMID:17728398

GO_REF:0000107 MGI:3833522

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Ptger4

prostaglandin E receptor 4

PMID:18254372 PMID:11991626

RGD

RGD:10003046, RGD:10003093

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

Sytl2

synaptotagmin-like 2

involved_in

(MGI:3693417|PMID:16716193)

PMID:16716193

MGI:3693417

NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222

positive regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Vamp8

vesicle-associated membrane protein 8

acts_upstream_of_or_within

MGI:3056083 (MGI:3801544|PMID:18535671)

PMID:18535671

MGI:3801544

NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897

positive regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nr1h2

nuclear receptor subfamily 1, group H, member 2

involved_in

(MGI:3822255|PMID:18806227)

PMID:11123201 PMID:21873635

PMID:18806227

MGI:3822255

NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377

Sct

secretin

involved_in

IDA
IBA

PMID:21873635

RGD
GO_Central

RGD:9590235, RGD:13792537

NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658

Spink1

serine peptidase inhibitor, Kazal type 1

RGD

PMID:2755938

RGD:10044250

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

positive regulation of pancreatic trypsinogen secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mmp13

matrix metallopeptidase 13

RGD

PMID:12771515

RGD:724699

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

positive regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:1939645)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

Gp1bb

glycoprotein Ib platelet subunit beta

involved_in

(PMID:1939645)

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

glycoprotein V (platelet)

involved_in

(PMID:1939645)

NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705

Gp9

glycoprotein IX (platelet)

involved_in

(PMID:1939645)

NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110

Jak2

Janus kinase 2

acts_upstream_of_or_within
involved_in

(PMID:31145836)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

podoplanin

RGD

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

Pla2g4a

phospholipase A2 group IVA

involved_in

(PMID:18451993)
GO_REF:0000107

PMID:18451993

GO_REF:0000107

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

Plek

pleckstrin

involved_in

(MGI:3844782|PMID:19190246)

PMID:19190246

MGI:3844782

NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131

Ptprj

protein tyrosine phosphatase, receptor type, J

involved_in

(MGI:3847185|PMID:19246339)

PMID:19246339

MGI:3847185

NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260

Selp

selectin P

involved_in

GO_REF:0000107
(MGI:3838274|PMID:16514062)

PMID:16514062

GO_REF:0000107 MGI:3838274

NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845

Tlr4

toll-like receptor 4

involved_in

GO_REF:0000107
(MGI:3838274|PMID:16514062)

PMID:16514062

GO_REF:0000107 MGI:3838274

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

positive regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctsg

cathepsin G

involved_in

(PMID:3390156)
GO_REF:0000024

PMID:3390156

GO_REF:0000024

NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353

Dmtn

dematin actin binding protein

involved_in

(MGI:5465511|PMID:23060452)

PMID:23060452

MGI:5465511

NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601

Emilin2

elastin microfibril interfacer 2

involved_in

(PMID:25658937)

PMID:25658937

NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352

F11r

F11 receptor

involved_in

(PMID:15344881)

PMID:15344881

NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402

Il6

interleukin 6

acts_upstream_of

(PMID:31145836)

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Il6r

interleukin 6 receptor

acts_upstream_of

(PMID:31145836)

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

Jak2

Janus kinase 2

acts_upstream_of
involved_in

(PMID:31145836)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Mmrn1

multimerin 1

involved_in
acts_upstream_of_or_within

(PMID:19175495)
(PMID:20138333)
GO_REF:0000107

PMID:19175495 PMID:20138333

GO_REF:0000107

NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474

Pdpn

podoplanin

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:3722196|PMID:17616532), (MGI:4453945|PMID:20110424)
PMID:21873635
(PMID:17222411), (PMID:17616532), (PMID:18541721), (PMID:20110424)

PMID:17222411 PMID:17616532 PMID:18541721 PMID:20110424 PMID:21873635

GO_REF:0000024 MGI:3722196 MGI:4453945, RGD:13792537

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

positive regulation of renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Inpp5k

inositol polyphosphate-5-phosphatase K

involved_in

(MGI:5299272|PMID:21938401)

PMID:21938401

MGI:5299272

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

positive regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor beta 1

RGD

NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259

aquaporin 1

involved_in

GO_REF:0000024
(PMID:15727941), (PMID:9096382)

PMID:9096382 PMID:15727941

GO_REF:0000024

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Tac1

tachykinin, precursor 1

RGD

PMID:11448478

RGD:5147474

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

Tac4

tachykinin precursor 4

acts_upstream_of_or_within

(MGI:1926622|PMID:11062498)

PMID:11062498

MGI:1926622

NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156

Tacr1

tachykinin receptor 1

RGD

PMID:11448478

RGD:5147474

NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733

positive regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2a

adenosine A2a receptor

in renal medulla

RGD

PMID:10070140

RGD:628573

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

Avpr1a

arginine vasopressin receptor 1A

involved_in

NAS

PMID:1560825

UniProt

PMID:1560825

RGD:1298691

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

betacellulin

RGD

NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049

Drd2

dopamine receptor D2

acts_upstream_of_or_within

MGI:1857875 (MGI:3608592|PMID:11566895)

PMID:11566895

MGI:3608592

NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875

Edn1

endothelin 1

acts_upstream_of_or_within

MGI:3044563|MGI:3054057|MGI:88121 (MGI:3612779|PMID:15632412)

PMID:15632412

MGI:3612779

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Ednrb

endothelin receptor type B

RGD

PMID:18305094

RGD:4892582

NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115

Gnai2

G protein subunit alpha i2

RGD

PMID:22459149

RGD:13507313

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

Has2

hyaluronan synthase 2

involved_in

PMID:19635555

UniProt

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

Hyal2

hyaluronidase 2

involved_in

PMID:19635555

UniProt

NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850

Inpp5k

inositol polyphosphate-5-phosphatase K

involved_in

(MGI:5299272|PMID:21938401)

PMID:21938401

MGI:5299272

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Nppb

natriuretic peptide B

RGD

PMID:8289999

RGD:7247315

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

Npr3

natriuretic peptide receptor 3

involved_in

GO_REF:0000024
(MGI:1339924|PMID:10377427)

PMID:10377427

GO_REF:0000024 MGI:1339924

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

Oprl1

opioid related nociceptin receptor 1

RGD

PMID:15010357

RGD:9835013

NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920

Ptger3

prostaglandin E receptor 3

acts_upstream_of_or_within

MGI:2157796 (MGI:1328864|PMID:9843913)

PMID:9843913

MGI:1328864

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

Ptger4

prostaglandin E receptor 4

RGD

PMID:18287210

RGD:10003052

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

Tfap2b

transcription factor AP-2 beta

involved_in

GO_REF:0000024
(MGI:2656435|PMID:12695560)

PMID:12695560

GO_REF:0000024 MGI:2656435

NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520

regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

acts_upstream_of_or_within

MGI:2157224 (MGI:1933877|PMID:11145969)

PMID:11145969

MGI:1933877

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

Cav1

caveolin 1

involved_in

GO_REF:0000107
(PMID:17848177)

PMID:17848177

GO_REF:0000107

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Ephb2

Eph receptor B2

involved_in

(PMID:30213874)

PMID:30213874

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

coagulation factor XI

acts_upstream_of_or_within

MGI:2384015 (MGI:3719506|PMID:16533887)

PMID:16533887

MGI:3719506

NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437

coagulation factor II (thrombin) receptor

involved_in

(PMID:17848177)

PMID:17848177

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

F2rl1

F2R like trypsin receptor 1

involved_in

(PMID:17848177)

PMID:17848177

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Foxa2

forkhead box A2

involved_in

(PMID:12911579)
GO_REF:0000107

PMID:12911579

GO_REF:0000107

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

histidine-rich glycoprotein

involved_in

GO_REF:0000107
(MGI:3789419|PMID:15869579)
GO_REF:0000024
(PMID:21304106), (PMID:6740558)

PMID:6740558 PMID:15869579 PMID:21304106

GO_REF:0000024 GO_REF:0000107 MGI:3789419

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

similar to histidine-rich glycoprotein

involved_in

ISS
IEA

GO_REF:0000024
GO_REF:0000107

UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

Vkorc1

vitamin K epoxide reductase complex, subunit 1

RGD

PMID:14765194

RGD:1303972

NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008

regulation of blood coagulation, intrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Serpinc1

serpin family C member 1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

regulation of blood volume by renal aldosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cyp11b3

cytochrome P450, family 11, subfamily b, polypeptide 3

involved_in

(PMID:14614232)

PMID:14614232

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

Hsd11b2

hydroxysteroid 11-beta dehydrogenase 2

RGD

PMID:15718388

RGD:1625109

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A2

RGD

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

apolipoprotein H

involved_in

(PMID:16480936)

PMID:16480936

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora1

adenosine A1 receptor

acts_upstream_of_or_within

MGI:2388340 (MGI:3606554|PMID:15283758)

PMID:15283758

MGI:3606554

NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801

Coro2b

coronin 2B

acts_upstream_of_or_within

MGI:4419137 (MGI:6110508|PMID:29162887)

PMID:29162887

MGI:6110508

NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302

Emp2

epithelial membrane protein 2

involved_in

GO_REF:0000024
(PMID:24814193)

PMID:24814193

GO_REF:0000024

NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733

Ptpro

protein tyrosine phosphatase, receptor type, O

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:1927435|PMID:11086029)
GO_REF:0000024

PMID:11086029 PMID:21873635

GO_REF:0000024 MGI:1927435, RGD:13792537

NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771

regulation of hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tph1

tryptophan hydroxylase 1

involved_in

GO_REF:0000024
(MGI:2683993|PMID:14697203)

PMID:14697203

GO_REF:0000024 MGI:2683993

NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344

regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Oas2

2'-5' oligoadenylate synthetase 2

involved_in

GO_REF:0000024
(MGI:6094812|PMID:29117179)

PMID:29117179

GO_REF:0000024 MGI:6094812

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nlrp6

NLR family, pyrin domain containing 6

acts_upstream_of_or_within

MGI:5085850 (MGI:5577214|PMID:24581500)

PMID:24581500

MGI:5577214

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer1g

Fc epsilon receptor Ig

involved_in

PMID:21873635
(MGI:87668|PMID:9171347)

PMID:9171347 PMID:21873635

MGI:87668, RGD:13792537

NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443

Fundc2

FUN14 domain containing 2

involved_in

(MGI:6506888|PMID:30576423)

PMID:30576423

MGI:6506888

NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345

histidine-rich glycoprotein

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:3789419|PMID:15869579), (MGI:4941083|PMID:21264222)
PMID:21873635

PMID:15869579 PMID:21264222 PMID:21873635

GO_REF:0000024 MGI:3789419 MGI:4941083, RGD:13792537

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

similar to histidine-rich glycoprotein

involved_in

ISS
IBA

GO_REF:0000024
PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353

Syk

spleen associated tyrosine kinase

involved_in

GO_REF:0000024
(MGI:87668|PMID:9171347)

PMID:9171347

GO_REF:0000024 MGI:87668

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Tec

tec protein tyrosine kinase

involved_in

PMID:21873635
(PMID:9299487), (PMID:9652744)

PMID:9299487 PMID:9652744 PMID:21873635

NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557

Txk

TXK tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448

regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Blk

BLK proto-oncogene, Src family tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031

Cela2a

chymotrypsin like elastase 2A

involved_in

(PMID:31358993)
GO_REF:0000024

PMID:31358993

GO_REF:0000024

NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632

Lyn

LYN proto-oncogene, Src family tyrosine kinase

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:5298337|PMID:20189992)
GO_REF:0000024

PMID:20189992 PMID:21873635

GO_REF:0000024 MGI:5298337, RGD:13792537

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Prkca

protein kinase C, alpha

involved_in

ISO
IEA
ISS

(PMID:12724315)
(MGI:3836381|PMID:19147982)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:12724315 PMID:19147982

GO_REF:0000024 GO_REF:0000107 MGI:3836381

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

Prkcq

protein kinase C, theta

involved_in

GO_REF:0000024
(MGI:3851048|PMID:19433059)
GO_REF:0000107

PMID:19433059

GO_REF:0000024 GO_REF:0000107 MGI:3851048

NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704

Syk

spleen associated tyrosine kinase

involved_in

IEA
ISO
IBA
ISS

GO_REF:0000107
(MGI:87668|PMID:9171347)
PMID:21873635
GO_REF:0000024

PMID:9171347 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:87668, RGD:13792537

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Vps33b

VPS33B, late endosome and lysosome associated

involved_in

(MGI:5645581|PMID:25947942)

PMID:25947942

MGI:5645581

NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970

regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fgf10

fibroblast growth factor 10

involved_in

(PMID:19102732)

PMID:19102732

NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866

Oprk1

opioid receptor, kappa 1

involved_in

GO_REF:0000024
(MGI:1197118|PMID:9463367)

PMID:9463367

GO_REF:0000024 MGI:1197118

NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823

regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adm

adrenomedullin

involved_in

(PMID:18434369)

PMID:18434369

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

Akr1b1

aldo-keto reductase family 1 member B

acts_upstream_of_or_within

MGI:2183239 (MGI:3628967|PMID:16449351)

PMID:16449351

MGI:3628967

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

Trpv5

transient receptor potential cation channel, subfamily V, member 5

involved_in

GO_REF:0000024
(MGI:2682494|PMID:14679186)

PMID:14679186

GO_REF:0000024 MGI:2682494

NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745

Umod

uromodulin

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:6094531|PMID:29145399), (MGI:6367886|PMID:29357410)

PMID:29145399 PMID:29357410

GO_REF:0000107 MGI:6094531 MGI:6367886

NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302

regulation of water loss via skin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acer1

alkaline ceramidase 1

involved_in

(MGI:5800647|PMID:27126290)

PMID:27126290

MGI:5800647

NCBI chr 9:1,792,790...1,824,434
Ensembl chr 9:1,793,139...1,824,434

Cdh1

cadherin 1

acts_upstream_of_or_within

MGI:2389020 (MGI:3574751|PMID:15775979)

PMID:15775979

MGI:3574751

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

Gba

glucosylceramidase beta

RGD

PMID:9101438

RGD:5508438

NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263

Scd

stearoyl-CoA desaturase

involved_in

(MGI:1859469|PMID:10854228)

PMID:10854228

MGI:1859469

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

Srf

serum response factor

acts_upstream_of_or_within

MGI:2445832|MGI:3522206 (MGI:4421610|PMID:20047077)

PMID:20047077

MGI:4421610

NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733

Tmprss11f

transmembrane serine protease 11F

acts_upstream_of_or_within

MGI:6360461|MGI:6364120 (MGI:6296037|PMID:28338078), (MGI:6363614|PMID:31501243)

PMID:28338078 PMID:31501243

MGI:6296037 MGI:6363614

NCBI chr14:21,492,896...21,534,792
Ensembl chr14:21,429,418...21,534,809

renal water absorption

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1

acts_upstream_of_or_within

MGI:1196668 MGI:1353208 MGI:1354610 MGI:1858888 MGI:1929327 MGI:2387728 MGI:3607623 MGI:3640845 MGI:3700886

PMID:9468475 PMID:10021457 PMID:10662735 PMID:10724035 PMID:10795927 More...

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Aqp3

aquaporin 3 (Gill blood group)

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:103201|MGI:2150021 (MGI:1858888|PMID:10795927), (MGI:1929327|PMID:11035042)

PMID:10795927 PMID:11035042

GO_REF:0000107 MGI:1858888 MGI:1929327

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

Aqp4

aquaporin 4

acts_upstream_of_or_within

MGI:103201|MGI:1857808 (MGI:1353208|PMID:10662735), (MGI:1858888|PMID:10795927)

PMID:10662735 PMID:10795927

MGI:1353208 MGI:1858888

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

Aqp7

aquaporin 7

acts_upstream_of_or_within

MGI:103201 (MGI:3607623|PMID:15998844)

PMID:15998844

MGI:3607623

NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642

Has2

hyaluronan synthase 2

involved_in

PMID:19635555

UniProt

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

Hyal2

hyaluronidase 2

involved_in

PMID:19635555

UniProt

NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850

Mllt6

MLLT6, PHD finger containing

acts_upstream_of_or_within

MGI:3856248 (MGI:5644399|PMID:21546577)

PMID:21546577

MGI:5644399

NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073

Sctr

secretin receptor

involved_in

(MGI:3709930|PMID:17283064)

PMID:17283064

MGI:3709930

NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189

renal water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcy6

adenylate cyclase 6

involved_in

GO_REF:0000024
(MGI:4457984|PMID:20466003)

PMID:20466003

GO_REF:0000024 MGI:4457984

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

Akap11

A-kinase anchoring protein 11

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:5751858 (MGI:5792167|PMID:27402760)

PMID:27402760

GO_REF:0000107 MGI:5792167

NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605

Akr1b1

aldo-keto reductase family 1 member B

acts_upstream_of_or_within

MGI:2183239 (MGI:3628967|PMID:16449351)

PMID:16449351

MGI:3628967

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

Aqp2

aquaporin 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:5792167|PMID:27402760)
(PMID:8140421)

PMID:8140421 PMID:27402760

GO_REF:0000024 MGI:5792167

NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468

Atp6v1b1

ATPase H+ transporting V1 subunit B1

acts_upstream_of_or_within

MGI:2673510 (MGI:5529401|PMID:24051376)

PMID:24051376

MGI:5529401

NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475

Tfap2b

transcription factor AP-2 beta

involved_in

GO_REF:0000024
(MGI:2656435|PMID:12695560)

PMID:12695560

GO_REF:0000024 MGI:2656435

NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520

Umod

uromodulin

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3531218|PMID:15522986)

PMID:15522986

GO_REF:0000107 MGI:3531218

NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302

Wfs1

wolframin ER transmembrane glycoprotein

involved_in

(PMID:9817917)

PMID:9817917

NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602

renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1

involved_in

ISS
IBA
ISO

GO_REF:0000024
PMID:21873635
(PMID:9096382)

PMID:9096382 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Aqp2

aquaporin 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856830 (MGI:57911|PMID:3184310)