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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T cell activation
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Accession:GO:0050868 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
Synonyms:exact_synonym: down regulation of T cell activation;   downregulation of T cell activation;   negative regulation of T lymphocyte activation
 narrow_synonym: inhibition of T cell activation


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negative regulation of T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G involved_in ISO
IEA
ISS		 (PMID:15100291)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15100291 GO_REF:0000024 GO_REF:0000107 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) RGD PMID:24714587 MGI:5583944 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO
IBA		 (PMID:12447358)
PMID:21873635		 RGD PMID:12447358 PMID:21873635 RGD:13792537 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Fgl1 fibrinogen-like 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:6273588|PMID:30580966)
PMID:21873635		 UniProt
RGD		 PMID:30580966 PMID:21873635 GO_REF:0000024 MGI:6273588, RGD:13792537 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:16584774 RGD:2303771 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3823129|PMID:18997793) RGD PMID:18997793 MGI:3823129 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:28891065) RGD PMID:28891065 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Ildr2 immunoglobulin-like domain containing receptor 2 involved_in ISO (PMID:29431694)
(MGI:6121682|PMID:29431694)		 RGD PMID:29431694 MGI:6121682 NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3655405|PMID:9498750)		 BHF-UCL
RGD		 PMID:9498750 GO_REF:0000024 MGI:3655405 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within
involved_in		 ISO (MGI:2429474|PMID:12421911)
(MGI:2385414|PMID:12209638), (MGI:6273588|PMID:30580966)		 RGD PMID:12209638 PMID:12421911 PMID:30580966 MGI:2385414 MGI:2429474 MGI:6273588 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in ISO
IBA		 (PMID:12359715)
PMID:21873635		 RGD PMID:12359715 PMID:21873635 RGD:13792537 NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:21112091) RGD PMID:21112091 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:24725595) RGD PMID:24725595 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 involved_in ISO
IBA
IEA		 (MGI:3687921|PMID:12612075)
PMID:21873635
GO_REF:0000002		 RGD
InterPro		 PMID:12612075 PMID:21873635 GO_REF:0000002 MGI:3687921, RGD:13792537 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:5291872|PMID:21874024) RGD PMID:21874024 MGI:5291872 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pla2g2d phospholipase A2, group IID acts_upstream_of_or_within ISO (MGI:3851856|PMID:19564598) RGD PMID:19564598 MGI:3851856 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4946183|PMID:21044313)
PMID:21873635
(PMID:18299186)		 BHF-UCL
RGD		 PMID:18299186 PMID:21044313 PMID:21873635 GO_REF:0000024 MGI:4946183, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Socs6 suppressor of cytokine signaling 6 acts_upstream_of_or_within ISO (MGI:4838967|PMID:20007709) RGD PMID:20007709 MGI:4838967 NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (MGI:3029937|PMID:9645617) RGD PMID:9645617 MGI:3029937 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3641518|PMID:12646629) RGD PMID:12646629 MGI:3641518 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tigit T cell immunoreceptor with Ig and ITIM domains involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:19011627)
MGI:4939784 (MGI:4939285|PMID:21199897)		 RGD PMID:19011627 PMID:21199897 PMID:21873635 MGI:4939285, RGD:13792537 NCBI chr11:57,029,024...57,046,627
Ensembl chr11:57,029,118...57,045,994 		JBrowse link
G Tnfaip8l2 TNF alpha induced protein 8 like 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5295125|PMID:21963221)		 RGD PMID:21963221 PMID:21873635 MGI:5295125, RGD:13792537 NCBI chr 2:182,710,433...182,726,724
Ensembl chr 2:182,709,378...182,726,760 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:16606666)
(MGI:3521625|PMID:15585831)		 RGD PMID:15585831 PMID:16606666 MGI:3521625 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
negative regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (MGI:5908339|PMID:19360123)
GO_REF:0000107		 RGD
Ensembl		 PMID:19360123 GO_REF:0000107 MGI:5908339 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 involved_in ISO (MGI:4453380|PMID:20208008) RGD PMID:20208008 MGI:4453380 NCBI chr17:41,653,499...41,664,246
Ensembl chr17:41,654,249...41,664,272 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within
involved_in		 ISO (MGI:5520006|PMID:23589618)
(MGI:4453380|PMID:20208008)		 RGD PMID:20208008 PMID:23589618 MGI:4453380 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:2178778 (MGI:2677082|PMID:12970760) RGD PMID:12970760 MGI:2677082 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:12538684)
(PMID:17489864)		 RGD PMID:12538684 PMID:17489864 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (MGI:3834299|PMID:18329370) RGD PMID:18329370 MGI:3834299 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3505776 (MGI:3776720|PMID:18077788)
GO_REF:0000107		 RGD
Ensembl		 PMID:18077788 GO_REF:0000107 MGI:3776720 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23817958) RGD PMID:23817958 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrrc32 leucine rich repeat containing 32 acts_upstream_of_or_within ISO (MGI:3807624|PMID:18628982) RGD PMID:18628982 MGI:3807624 NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:21112091) RGD PMID:21112091 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 involved_in ISO (PMID:12538684) RGD PMID:12538684 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO
IEA		 (PMID:17911601)
GO_REF:0000107		 RGD
Ensembl		 PMID:17911601 GO_REF:0000107 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prnp prion protein involved_in ISO (MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:4943618 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5284769|PMID:18172933) RGD PMID:18172933 MGI:5284769 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (MGI:3834299|PMID:18329370) RGD PMID:18329370 MGI:3834299 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO (MGI:3822045|PMID:10069416) RGD PMID:10069416 MGI:3822045 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) RGD PMID:19667090 MGI:4355451 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:1888832|PMID:10981962)		 Ensembl
RGD		 PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (MGI:3521631|PMID:15568026) RGD PMID:15568026 MGI:3521631 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (MGI:5475030|PMID:23487419) RGD PMID:23487419 MGI:5475030 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034 (MGI:3692513|PMID:16945588) RGD PMID:16945588 MGI:3692513 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Skint2 selection and upkeep of intraepithelial T cells 2 acts_upstream_of_or_within ISO (MGI:3830586|PMID:17339463) RGD PMID:17339463 MGI:3830586 NCBI chr 5:126,878,834...126,909,044
Ensembl chr 5:126,875,682...126,913,167 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (PMID:26311901) RGD PMID:26311901 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:3772948 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3772948|PMID:18258917)		 UniProt
RGD		 PMID:18258917 GO_REF:0000024 MGI:3772948 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:3772948 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5908533|PMID:25009204)		 Ensembl
RGD		 PMID:25009204 GO_REF:0000107 MGI:5908533 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2180572 (MGI:3038342|PMID:14973438)
GO_REF:0000107		 RGD
Ensembl		 PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:3697020|PMID:17028180) RGD PMID:17028180 MGI:3697020 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:1856404 (MGI:3038342|PMID:14973438) RGD PMID:14973438 MGI:3038342 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Lgals5 galectin 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153 		JBrowse link
G Lgals9 galectin 9 involved_in ISO
IBA		 (PMID:20209097)
(MGI:5688819|PMID:25065622)
PMID:21873635		 RGD PMID:20209097 PMID:25065622 PMID:21873635 MGI:5688819, RGD:13792537 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3695433 (MGI:3694584|PMID:17137798)
GO_REF:0000107		 RGD
Ensembl		 PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) RGD PMID:26311901 MGI:5908526 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (MGI:3521631|PMID:15568026) RGD PMID:15568026 MGI:3521631 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:24691993)
(MGI:5292805|PMID:21383057)		 RGD PMID:21383057 PMID:24691993 MGI:5292805 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Dapl1 death associated protein-like 1 involved_in ISO (MGI:7414447|PMID:35773432) RGD PMID:35773432 MGI:7414447 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Skint2 selection and upkeep of intraepithelial T cells 2 acts_upstream_of_or_within ISO (MGI:3830586|PMID:17339463) RGD PMID:17339463 MGI:3830586 NCBI chr 5:126,878,834...126,909,044
Ensembl chr 5:126,875,682...126,913,167 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6840447|PMID:24515893)		 UniProt
RGD		 PMID:24515893 GO_REF:0000024 MGI:6840447 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6140589|PMID:24880459)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24880459 GO_REF:0000024 GO_REF:0000107 MGI:6140589 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459) RGD PMID:22730529 PMID:24880459 MGI:5446998 MGI:6140589 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6840447|PMID:24515893)		 UniProt
RGD		 PMID:24515893 GO_REF:0000024 MGI:6840447 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:18424730)
GO_REF:0000024		 RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
negative regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035) RGD PMID:16493035 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
negative regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO
ISS		 (PMID:23241886)
GO_REF:0000024		 RGD
UniProt		 PMID:23241886 GO_REF:0000024 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
negative regulation of immature T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnrh1 gonadotropin releasing hormone 1 IMP RGD PMID:11092955 RGD:9685051 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12421925)		 Ensembl
UniProt
RGD		 PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (MGI:3615850|PMID:15964995) RGD PMID:15964995 MGI:3615850 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (MGI:5475030|PMID:23487419) RGD PMID:23487419 MGI:5475030 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695084|PMID:16230479)
GO_REF:0000107		 RGD
Ensembl		 PMID:16230479 GO_REF:0000107 MGI:3695084 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO (PMID:23690469) RGD PMID:23690469 NCBI chr 2:169,257,659...169,391,773
Ensembl chr 2:169,258,289...169,391,711 		JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235 		JBrowse link
negative regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:10540326) RGD PMID:10540326 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:5449456 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5320871|PMID:22080863)		 UniProt
Ensembl
RGD		 PMID:22080863 GO_REF:0000024 GO_REF:0000107 MGI:5320871 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in IBA
ISO		 PMID:21873635
(PMID:18641304)		 RGD PMID:18641304 PMID:21873635 RGD:13792537 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3803082|PMID:18641303)		 UniProt
RGD		 PMID:18641303 GO_REF:0000024 MGI:3803082 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3510279|PMID:15485628)		 UniProt
RGD		 PMID:15485628 GO_REF:0000024 MGI:3510279 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Mdk midkine involved_in ISO
IEA
ISS		 (PMID:22323540)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22323540 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS0000338542_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) RGD PMID:18713990 MGI:3806904 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927 		JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) RGD PMID:19706535 MGI:4355752 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
negative regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (MGI:52620|PMID:7679955) RGD PMID:7679955 MGI:52620 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:5449492|PMID:23066153) RGD PMID:23066153 MGI:5449492 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 acts_upstream_of_or_within ISO (MGI:2663321|PMID:12794108) RGD PMID:12794108 MGI:2663321 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235 		JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein acts_upstream_of_or_within ISO (MGI:2663321|PMID:12794108) RGD PMID:12794108 MGI:2663321 NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (MGI:3796974|PMID:16290204)		 Ensembl
RGD		 PMID:16290204 GO_REF:0000107 MGI:3796974 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:12421925) RGD PMID:12421925 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Foxj1 forkhead box J1 involved_in ISO
IEA		 (MGI:3713603|PMID:16339515)
GO_REF:0000107		 RGD
Ensembl		 PMID:16339515 GO_REF:0000107 MGI:3713603 NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (MGI:2177878|PMID:11931770) RGD PMID:11931770 MGI:2177878 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1888832|PMID:10981962)
GO_REF:0000107		 RGD
Ensembl		 PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 involved_in ISO (PMID:12153508) RGD PMID:12153508 NCBI chr 3:116,176,779...116,193,752
Ensembl chr 3:116,176,798...116,193,787 		JBrowse link
negative regulation of T cell homeostatic proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (MGI:3721471|PMID:16769998) RGD PMID:16769998 MGI:3721471 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
negative regulation of T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:16709924) RGD PMID:16709924 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (MGI:2665193|PMID:12796776) RGD PMID:12796776 MGI:2665193 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Cd274 CD274 molecule acts_upstream_of_or_within ISO (MGI:3689239|PMID:17016562) RGD PMID:17016562 MGI:3689239 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO MGI:3033707 (MGI:2671029|PMID:12925852) RGD PMID:12925852 MGI:2671029 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:1350360 (MGI:4830018|PMID:20709950) RGD PMID:20709950 MGI:4830018 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:3695215 (MGI:3693042|PMID:17081782), (MGI:5451119|PMID:23123061) RGD PMID:17081782 PMID:23123061 MGI:3693042 MGI:5451119 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3773092|PMID:16585579)		 UniProt
Ensembl
RGD		 PMID:16585579 GO_REF:0000024 GO_REF:0000107 MGI:3773092 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO (MGI:5510582|PMID:19632227) RGD PMID:19632227 MGI:5510582 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP RGD PMID:15849541 RGD:2302005 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3699270 (MGI:3768613|PMID:17724087)		 Ensembl
RGD		 PMID:17724087 GO_REF:0000107 MGI:3768613 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:28169360) RGD PMID:28169360 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837 		JBrowse link
G Foxj1 forkhead box J1 involved_in ISO
IEA		 (MGI:3043440|PMID:14963332)
GO_REF:0000107		 RGD
Ensembl		 PMID:14963332 GO_REF:0000107 MGI:3043440 NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within		 ISO (PMID:15466453), (PMID:21458306), (PMID:23169781)
MGI:1857034 (MGI:3607665|PMID:16203996), (MGI:3693968|PMID:16769892)		 RGD PMID:15466453 PMID:16203996 PMID:16769892 PMID:21458306 PMID:23169781 MGI:3607665 MGI:3693968 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Glmn glomulin, FKBP associated protein involved_in ISO (PMID:12604780) RGD PMID:12604780 NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:2679123|PMID:14556006) RGD PMID:14556006 MGI:2679123 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within ISO MGI:3505776 (MGI:3776720|PMID:18077788) RGD PMID:18077788 MGI:3776720 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO MGI:3830304 (MGI:3827040|PMID:19124723) RGD PMID:19124723 MGI:3827040 NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1857192 (MGI:2670301|PMID:12702495) RGD PMID:12702495 MGI:2670301 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132) RGD PMID:17356132 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Kng2 kininogen 2 IDA unstimulated Jurkat cells; ConA- or PHA-stimulated, but not IL-2 stimulated, Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:17163451) RGD PMID:17163451 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 acts_upstream_of_or_within ISO (MGI:1932181|PMID:11313860) RGD PMID:11313860 MGI:1932181 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3530008 (MGI:3529633|PMID:15670816)
GO_REF:0000107		 RGD
Ensembl		 PMID:15670816 GO_REF:0000107 MGI:3529633 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (MGI:2675524|PMID:12970181) RGD PMID:12970181 MGI:2675524 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 acts_upstream_of_or_within ISO (MGI:1931613|PMID:11224527), (MGI:3689239|PMID:17016562) RGD PMID:11224527 PMID:17016562 MGI:1931613 MGI:3689239 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Pde5a phosphodiesterase 5A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3722008|PMID:17101732)
GO_REF:0000107		 RGD
Ensembl		 PMID:17101732 GO_REF:0000107 MGI:3722008 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:5291872|PMID:21874024) RGD PMID:21874024 MGI:5291872 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pla2g2a phospholipase A2 group IIA NOT|acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3851856|PMID:19564598)
PMID:21873635		 RGD PMID:19564598 PMID:21873635 MGI:3851856, RGD:13792537 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2d phospholipase A2, group IID acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3851856|PMID:19564598)
PMID:21873635		 RGD PMID:19564598 PMID:21873635 MGI:3851856, RGD:13792537 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3695953|PMID:16931517)		 RGD PMID:16931517 PMID:21873635 MGI:3695953, RGD:13792537 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857936 (MGI:3586939|PMID:16027169) RGD PMID:16027169 MGI:3586939 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856073|MGI:1856074 (MGI:82729|PMID:9064344)		 Ensembl
RGD		 PMID:9064344 GO_REF:0000107 MGI:82729 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO (PMID:27556504) RGD PMID:27556504 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
G RT1-Ba RT1 class II, locus Ba IDA RGD PMID:9834080 RGD:5147666 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Bb RT1 class II, locus Bb IDA RGD PMID:9834080 RGD:5147666 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:15795121) RGD PMID:15795121 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:20702625) RGD PMID:20702625 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 acts_upstream_of_or_within ISO (MGI:3615741|PMID:15356574) RGD PMID:15356574 MGI:3615741 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Sdc4 syndecan 4 involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sftpd surfactant protein D IDA RGD PMID:9794387 RGD:4144057 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:1888832|PMID:10981962)		 Ensembl
RGD		 PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Spn sialophorin involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857246 (MGI:3029937|PMID:9645617), (MGI:3510556|PMID:15117976), (MGI:76803|PMID:7566153)
(MGI:3847636|PMID:17638845)		 UniProt
RGD		 PMID:7566153 PMID:9645617 PMID:15117976 PMID:17638845 GO_REF:0000024 MGI:3029937 MGI:3510556 MGI:3847636 MGI:76803 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:3719583 (MGI:3718815|PMID:17481928) RGD PMID:17481928 MGI:3718815 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:2137821|PMID:11485735)
PMID:21873635		 UniProt
RGD		 PMID:11485735 PMID:21873635 GO_REF:0000024 MGI:2137821, RGD:13792537 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO MGI:109583 (MGI:3586939|PMID:16027169) RGD PMID:16027169 MGI:3586939 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:88330 (MGI:4830018|PMID:20709950) RGD PMID:20709950 MGI:4830018 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3689239|PMID:17016562)		 RGD PMID:17016562 PMID:21873635 MGI:3689239, RGD:13792537 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in ISO (PMID:16606666) RGD PMID:16606666 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D acts_upstream_of_or_within ISO MGI:5588370 (MGI:5567042|PMID:24415781) RGD PMID:24415781 MGI:5567042 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) RGD PMID:24463518 MGI:5565031 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3719947|PMID:16020505)		 BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) RGD PMID:9670042 MGI:4942267 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) RGD PMID:24463518 MGI:5565031 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) RGD PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (MGI:5634593|PMID:25642768) RGD PMID:25642768 MGI:5634593 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3817792|PMID:18792410)		 RGD PMID:18792410 PMID:21873635 MGI:3817792, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5634593|PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO MGI:3530739 (MGI:5450776|PMID:23034280) RGD PMID:23034280 MGI:5450776 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(MGI:6142401|PMID:25282160)		 UniProt
RGD		 PMID:25282160 GO_REF:0000024 MGI:6142401 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in ISO (MGI:5825383|PMID:28065600) RGD PMID:28065600 MGI:5825383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:17008549)		 UniProt
RGD		 PMID:17008549 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) RGD PMID:24463518 MGI:5565031 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:96559 (MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:2450484 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:105367|MGI:2182089 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:3687909 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Zfp35 zinc finger protein 35 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr18:15,268,852...15,284,334
Ensembl chr18:15,268,814...15,285,088 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO MGI:3581675 (MGI:3580753|PMID:15917799) RGD PMID:15917799 MGI:3580753 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    negative regulation of biological process 5661
      negative regulation of immune system process 550
        negative regulation of leukocyte activation 224
          negative regulation of lymphocyte activation 188
            negative regulation of T cell activation 146
              negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
              negative regulation of T cell differentiation + 58
              negative regulation of T cell proliferation + 83
              negative regulation of alpha-beta T cell activation + 50
              negative regulation of cytotoxic T cell degranulation 2
              negative regulation of establishment of T cell polarity 1
              negative regulation of gamma-delta T cell activation + 0
Path 2
Term Annotations click to browse term
  biological_process 19527
    biological regulation 13192
      regulation of biological process 12837
        regulation of cellular process 12317
          regulation of cell activation 683
            regulation of leukocyte activation 631
              regulation of lymphocyte activation 515
                regulation of T cell activation 373
                  negative regulation of T cell activation 146
                    negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
                    negative regulation of T cell differentiation + 58
                    negative regulation of T cell proliferation + 83
                    negative regulation of alpha-beta T cell activation + 50
                    negative regulation of cytotoxic T cell degranulation 2
                    negative regulation of establishment of T cell polarity 1
                    negative regulation of gamma-delta T cell activation + 0
paths to the root