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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of antigen receptor-mediated signaling pathway
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Accession:GO:0050857 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms:exact_synonym: positive regulation of antigen receptor mediated signalling pathway;   up regulation of antigen receptor-mediated signaling pathway;   upregulation of antigen receptor-mediated signaling pathway
 narrow_synonym: activation of antigen receptor-mediated signaling pathway;   stimulation of antigen receptor-mediated signaling pathway


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positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3687418|PMID:8692271)		 UniProt
RGD		 PMID:8692271 GO_REF:0000024 MGI:3687418 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5476553|PMID:23499492)
(PMID:20237408)		 UniProt
Ensembl
RGD		 PMID:20237408 PMID:23499492 GO_REF:0000024 GO_REF:0000107 MGI:5476553 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (MGI:3047050|PMID:15196959) RGD PMID:15196959 MGI:3047050 NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in ISO (MGI:3044463|PMID:15143214) RGD PMID:15143214 MGI:3044463 NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3700457|PMID:16301747)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16301747 GO_REF:0000024 GO_REF:0000107 MGI:3700457 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkch protein kinase C, eta involved_in ISS
ISO		 GO_REF:0000024
(PMID:18780722)		 UniProt
RGD		 PMID:18780722 GO_REF:0000024 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5642299 (MGI:5586914|PMID:25074919)		 RGD PMID:25074919 PMID:21873635 MGI:5586914, RGD:13792537 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO
IBA		 (PMID:10518561)
PMID:21873635		 RGD PMID:10518561 PMID:21873635 RGD:13792537 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3640996|PMID:11435465) RGD PMID:11435465 MGI:3640996 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:18287044), (PMID:27777308)		 UniProt
RGD		 PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)		 RGD PMID:12154356 PMID:12154360 MGI:6695669 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) RGD PMID:17785582 MGI:3847607 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Cd226 CD226 molecule involved_in ISO
IBA		 (PMID:26755705)
PMID:21873635		 RGD PMID:26755705 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO
IEA
ISS		 (PMID:23858057)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23858057 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO MGI:3664438 (MGI:3656194|PMID:16501569) RGD PMID:16501569 MGI:3656194 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISS
ISO		 GO_REF:0000024
(PMID:18287044), (PMID:27777308)		 UniProt
RGD		 PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18796614)		 Ensembl
RGD		 PMID:18796614 GO_REF:0000107 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA		 (PMID:26755705)
PMID:21873635		 RGD PMID:26755705 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4849903|PMID:20819079)		 UniProt
RGD		 PMID:20819079 GO_REF:0000024 MGI:4849903 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) RGD PMID:26021297 NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11390434)
PMID:21873635		 RGD PMID:11390434 PMID:21873635 RGD:13792537 NCBI chr11:52,035,750...52,077,805
Ensembl chr11:52,035,750...52,077,805 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      signal transduction 6997
        positive regulation of signal transduction 1639
          positive regulation of antigen receptor-mediated signaling pathway 24
            positive regulation of B cell receptor signaling pathway 8
            positive regulation of T cell receptor signaling pathway 16
Path 2
Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological process 13033
        regulation of immune system process 1543
          positive regulation of immune system process 1020
            positive regulation of immune response 640
              activation of immune response 413
                immune response-activating signal transduction 332
                  immune response-activating cell surface receptor signaling pathway 331
                    antigen receptor-mediated signaling pathway 282
                      regulation of antigen receptor-mediated signaling pathway 65
                        positive regulation of antigen receptor-mediated signaling pathway 24
                          positive regulation of B cell receptor signaling pathway 8
                          positive regulation of T cell receptor signaling pathway 16
paths to the root