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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of B cell receptor signaling pathway
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Accession:GO:0050855 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms:exact_synonym: regulation of B cell receptor signalling pathway;   regulation of B lymphocyte receptor signaling pathway;   regulation of B lymphocyte receptor signalling pathway
 xref: Reactome:R-HSA-8939245 "RUNX1 regulates transcription of genes involved in BCR signaling"


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regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (PMID:9382888) RGD PMID:9382888 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Fcmr Fc mu receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:28135254)		 UniProt
RGD		 PMID:28135254 GO_REF:0000024 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Gcsam germinal center-associated, signaling and motility involved_in ISO
IBA		 (PMID:23299888)
GO_REF:0000033		 RGD
GO_Central		 PMID:23299888 GO_REF:0000033 NCBI chr11:55,195,757...55,207,011
Ensembl chr11:55,196,712...55,206,992 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:11672542)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:11672542 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO
IBA		 (PMID:24169826), (PMID:26017478)
GO_REF:0000033		 RGD
GO_Central		 PMID:24169826 PMID:26017478 GO_REF:0000033 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:21482706) RGD PMID:21482706 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd72 Cd72 molecule involved_in ISO (PMID:1711157) RGD PMID:1711157 NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcrl5 Fc receptor-like 5 acts_upstream_of_or_within ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Lpxn leupaxin involved_in ISO
IBA		 (PMID:17640867)
GO_REF:0000033		 RGD
GO_Central		 PMID:17640867 GO_REF:0000033 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084 		JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO MGI:2679632 (PMID:14517301) RGD PMID:14517301 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA		 (PMID:35941532)
GO_REF:0000107		 RGD
Ensembl		 PMID:35941532 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20237408)
GO_REF:0000107
(PMID:23499492)		 UniProt
RGD
Ensembl		 PMID:20237408 PMID:23499492 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) RGD PMID:15196959 NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:24169826), (PMID:26017478) RGD PMID:24169826 PMID:26017478 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442 		JBrowse link
G Prkch protein kinase C, eta involved_in ISO
ISS		 (PMID:18780722)
GO_REF:0000024		 RGD
UniProt		 PMID:18780722 GO_REF:0000024 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO MGI:5642299 (PMID:25074919) RGD PMID:25074919 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO
IBA		 (PMID:10518561)
GO_REF:0000033		 RGD
GO_Central		 PMID:10518561 GO_REF:0000033 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    immune system process 3111
      regulation of immune system process 1732
        regulation of immune response 1045
          regulation of antigen receptor-mediated signaling pathway 71
            regulation of B cell receptor signaling pathway 23
              negative regulation of B cell receptor signaling pathway 10
              positive regulation of B cell receptor signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 20537
    biological regulation 13819
      regulation of biological process 13374
        regulation of immune system process 1732
          regulation of immune response 1045
            positive regulation of immune response 822
              activation of immune response 588
                immune response-activating signaling pathway 504
                  immune response-activating cell surface receptor signaling pathway 303
                    antigen receptor-mediated signaling pathway 192
                      B cell receptor signaling pathway 61
                        regulation of B cell receptor signaling pathway 23
                          negative regulation of B cell receptor signaling pathway 10
                          positive regulation of B cell receptor signaling pathway 9
paths to the root