Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of antigen receptor-mediated signaling pathway
go back to main search page
Accession:GO:0050854 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms:exact_synonym: regulation of antigen receptor mediated signalling pathway

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO (PMID:24169826)
(PMID:26017478)		 ARUK-UCL PMID:24169826 PMID:26017478 NCBI chrNW_004955468:4,609,601...4,622,601
Ensembl chrNW_004955468:4,612,044...4,625,882 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004955468:9,434,654...9,464,907
Ensembl chrNW_004955468:9,435,804...9,465,024 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004955467:9,600,829...9,604,148
Ensembl chrNW_004955467:9,600,829...9,603,606 		JBrowse link
G Lpxn leupaxin involved_in ISO (PMID:17640867)
(MGI:3722965|PMID:17640867)		 UniProt PMID:17640867 MGI:3722965 NCBI chrNW_004955511:3,459,521...3,500,181
Ensembl chrNW_004955511:3,459,378...3,497,416 		JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within ISO (PMID:14517301) MGI PMID:14517301 NCBI chrNW_004955430:9,157,074...9,347,366
Ensembl chrNW_004955430:9,157,074...9,348,563 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btnl2 butyrophilin like 2 acts_upstream_of_or_within ISO (PMID:16751379) MGI PMID:16751379 NCBI chrNW_004955437:1,084,330...1,101,751
Ensembl chrNW_004955437:1,083,745...1,101,730 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chrNW_004955422:1,658,237...1,687,000
Ensembl chrNW_004955422:1,657,926...1,695,404 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (PMID:24714587) MGI PMID:24714587 NCBI chrNW_004955465:12,551,063...12,597,386
Ensembl chrNW_004955465:12,551,063...12,592,572 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:12447358) UniProt PMID:12447358 NCBI chrNW_004955451:17,064,739...17,069,964 JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955404:50,952,907...51,020,229
Ensembl chrNW_004955404:50,952,907...51,020,229 		JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004955439:3,701,722...3,740,345
Ensembl chrNW_004955439:3,703,013...3,740,345 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (PMID:12970181) MGI PMID:12970181 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710 		JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004955513:4,930,951...4,932,509
Ensembl chrNW_004955513:4,930,951...4,932,509 		JBrowse link
G Prnp prion protein (Kanno blood group) involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chrNW_004955415:15,442,313...15,454,644
Ensembl chrNW_004955415:15,442,313...15,454,644 		JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:12913111)
(MGI:4942249|PMID:12913111)
(PMID:11259588), (PMID:9780142)		 UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chrNW_004955422:396,266...438,792
Ensembl chrNW_004955422:399,357...443,054 		JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955573:592,438...595,056 JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chrNW_004955473:10,345,407...10,370,535
Ensembl chrNW_004955473:10,346,943...10,370,575 		JBrowse link
G Sla2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219 NCBI chrNW_004955422:24,978,447...25,003,732
Ensembl chrNW_004955422:24,986,028...25,003,732 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chrNW_004955412:20,480,284...20,484,958
Ensembl chrNW_004955412:20,480,284...20,484,958 		JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing A acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955407:39,290,025...39,325,810
Ensembl chrNW_004955407:39,290,827...39,326,004 		JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:20237408)
(MGI:5476553|PMID:23499492)		 UniProt PMID:20237408 PMID:23499492 MGI:5476553 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Cmtm3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chrNW_004955433:23,178,062...23,185,666
Ensembl chrNW_004955433:23,178,061...23,185,666 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in ISO (MGI:3044463|PMID:15143214) HGNC-UCL PMID:15143214 MGI:3044463 NCBI chrNW_004955413:27,865,672...27,893,793
Ensembl chrNW_004955413:27,866,271...27,893,844 		JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934 		JBrowse link
G Prkch protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chrNW_004955466:8,178,323...8,393,446
Ensembl chrNW_004955466:8,176,876...8,393,446 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (PMID:25074919) MGI PMID:25074919 NCBI chrNW_004955403:4,426,538...4,479,693 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:10518561) BHF-UCL PMID:10518561 NCBI chrNW_004955447:5,292,708...5,345,214
Ensembl chrNW_004955447:5,293,227...5,330,187 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Card11 caspase recruitment domain family member 11 involved_in ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)		 UniProt PMID:12154356 PMID:12154360 MGI:6695669 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) BHF-UCL PMID:17785582 MGI:3847607 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955402:53,408,861...53,560,896
Ensembl chrNW_004955402:53,473,131...53,560,924 		JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (PMID:16501569) MGI PMID:16501569 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004955580:1,053,823...1,069,802
Ensembl chrNW_004955580:1,053,823...1,069,802 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004955555:1,493,600...1,509,113
Ensembl chrNW_004955555:1,490,052...1,509,113 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:19179613) MGI PMID:19179613 NCBI chrNW_004955425:3,718,291...3,755,942
Ensembl chrNW_004955425:3,718,206...3,756,142 		JBrowse link
G LOC102018114 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chrNW_004955427:9,665,479...9,700,305
Ensembl chrNW_004955427:9,665,456...9,699,788 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955555:1,959,702...1,985,679 JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chrNW_004955574:723,933...750,794
Ensembl chrNW_004955574:723,933...750,793 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chrNW_004955406:41,452,733...41,468,467
Ensembl chrNW_004955406:41,462,534...41,468,948 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004955414:16,436,899...16,442,325
Ensembl chrNW_004955414:16,436,899...16,443,073 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in ISO (MGI:5432321|PMID:22561606) UniProt PMID:22561606 MGI:5432321 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (PMID:9382888)
(MGI:1100180|PMID:9382888)		 UniProt PMID:9382888 MGI:1100180 NCBI chrNW_004955493:6,540,160...6,544,077 JBrowse link
G Fcmr Fc mu receptor involved_in ISO (MGI:5888941|PMID:28135254) UniProt PMID:28135254 MGI:5888941 NCBI chrNW_004955406:42,438,173...42,452,339
Ensembl chrNW_004955406:42,438,783...42,452,163 		JBrowse link
G Gcsam germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chrNW_004955427:12,524,261...12,533,773
Ensembl chrNW_004955427:12,524,654...12,536,645 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:2152233|PMID:11672542) UniProt PMID:11672542 MGI:2152233 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310 		JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      signal transduction 3939
        regulation of signal transduction 2620
          regulation of antigen receptor-mediated signaling pathway 62
            negative regulation of antigen receptor-mediated signaling pathway + 30
            positive regulation of antigen receptor-mediated signaling pathway + 25
            regulation of B cell receptor signaling pathway + 19
            regulation of T cell receptor signaling pathway + 44
Path 2
Term Annotations click to browse term
  biological_process 12321
    biological regulation 8863
      regulation of biological process 8603
        regulation of immune system process 1310
          positive regulation of immune system process 912
            positive regulation of immune response 586
              activation of immune response 430
                immune response-activating signaling pathway 388
                  immune response-activating cell surface receptor signaling pathway 232
                    antigen receptor-mediated signaling pathway 152
                      regulation of antigen receptor-mediated signaling pathway 62
                        negative regulation of antigen receptor-mediated signaling pathway + 30
                        positive regulation of antigen receptor-mediated signaling pathway + 25
                        regulation of B cell receptor signaling pathway + 19
                        regulation of T cell receptor signaling pathway + 44
paths to the root