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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell receptor signaling pathway
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Accession:GO:0050853 term browser browse the term
Definition:A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms:exact_synonym: B cell receptor signalling pathway;   B lymphocyte receptor signaling pathway;   B lymphocyte receptor signalling pathway


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B cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 9:130,713,881...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G AC135068.2 novel protein, identical to IGHV4-4 IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:21,742,364...21,742,799 JBrowse link
G AL121845.2 novel transcript, LIME1-SLC2A4RG readthrough IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr20:63,738,270...63,740,398 JBrowse link
G AL121845.3 novel protein, ZGPAT-LIME1 readthrough IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr20:63,708,864...63,739,103 JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member IDA (PMID:9020138) UniProtKB PMID:9020138 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053
JBrowse link
G BCL2 BCL2 apoptosis regulator IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase IDA (PMID:876631) UniProtKB PMID:876631 NCBI chr 8:11,493,991...11,564,599
Ensembl chr 8:11,486,894...11,564,599
JBrowse link
G BLNK B cell linker IDA (PMID:9697839) UniProt PMID:9697839 NCBI chr10:96,189,171...96,271,569
Ensembl chr10:96,191,702...96,271,587
Ensembl chr10:96,191,702...96,271,587
JBrowse link
G BMX BMX non-receptor tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:15,500,777...15,556,519
Ensembl chr  X:15,464,246...15,556,529
JBrowse link
G BTK Bruton tyrosine kinase TAS (PMID:19290921) UniProtKB PMID:19290921 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,447...101,390,796
JBrowse link
G CD19 CD19 molecule IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr16:28,931,735...28,939,347
Ensembl chr16:28,931,965...28,939,342
Ensembl chr16:28,931,965...28,939,342
JBrowse link
G CD38 CD38 molecule IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CD79A CD79a molecule ISS
IEA
IBA
(PMID:21873635) UniProtKB
InterPro
GO_Central
PMID:21873635 GO_REF:0000002, GO_REF:0000024 NCBI chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372
JBrowse link
G CD79B CD79b molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,740...63,932,354
Ensembl chr17:63,928,740...63,932,354
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IMP
IBA
(PMID:17875758)
(PMID:21873635)
UniProtKB
GO_Central
PMID:17875758, PMID:21873635 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G IGHA1 immunoglobulin heavy constant alpha 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,707,168...105,708,664
Ensembl chr14:105,703,995...105,708,665
JBrowse link
G IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,586,937...105,588,394
Ensembl chr14:105,583,731...105,588,395
JBrowse link
G IGHD immunoglobulin heavy constant delta IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,838,401...105,845,677
Ensembl chr14:105,836,765...105,845,678
JBrowse link
G IGHE immunoglobulin heavy constant epsilon IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,600,066...105,601,727
Ensembl chr14:105,597,691...105,601,728
JBrowse link
G IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,741,473...105,743,070
Ensembl chr14:105,736,343...105,743,071
JBrowse link
G IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,643,203...105,644,789
Ensembl chr14:105,639,559...105,644,790
JBrowse link
G IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,765,914...105,771,405
Ensembl chr14:105,764,503...105,771,405
JBrowse link
G IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,624,476...105,626,065
Ensembl chr14:105,620,506...105,626,066
JBrowse link
G IGHM immunoglobulin heavy constant mu IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218
JBrowse link
G IGHV1-18 immunoglobulin heavy variable 1-18 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,184,899...106,185,335
Ensembl chr14:106,184,901...106,185,394
JBrowse link
G IGHV1-2 immunoglobulin heavy variable 1-2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,986,582...105,987,019
Ensembl chr14:105,986,582...105,987,083
JBrowse link
G IGHV1-24 immunoglobulin heavy variable 1-24 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,276,546...106,276,983
Ensembl chr14:106,276,548...106,277,043
JBrowse link
G IGHV1-3 immunoglobulin heavy variable 1-3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,005,095...106,005,532
Ensembl chr14:106,005,095...106,005,574
JBrowse link
G IGHV1-45 immunoglobulin heavy variable 1-45 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,506,996...106,507,433
Ensembl chr14:106,506,996...106,507,491
JBrowse link
G IGHV1-46 immunoglobulin heavy variable 1-46 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,511,115...106,511,552
Ensembl chr14:106,511,117...106,511,856
JBrowse link
G IGHV1-58 immunoglobulin heavy variable 1-58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,622,357...106,622,794
Ensembl chr14:106,622,357...106,622,855
JBrowse link
G IGHV1-69 immunoglobulin heavy variable 1-69 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,714,682...106,715,120
Ensembl chr14:106,714,684...106,715,181
JBrowse link
G IGHV1-69-2 immunoglobulin heavy variable 1-69-2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,737,110...106,737,547
Ensembl chr14:106,737,110...106,737,547
JBrowse link
G IGHV1-69D immunoglobulin heavy variable 1-69D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,762,092...106,762,530
Ensembl chr14:106,762,092...106,762,588
JBrowse link
G IGHV1-8 immunoglobulin heavy variable 1-8 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV1OR15-1 immunoglobulin heavy variable 1/OR15-1 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:22,160,289...22,160,930
Ensembl chr15:21,717,808...21,718,245
Ensembl chr15:21,717,808...21,718,245
JBrowse link
G IGHV1OR15-9 immunoglobulin heavy variable 1/OR15-9 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:19,964,656...19,965,101
Ensembl chr15:19,964,666...19,965,101
JBrowse link
G IGHV1OR21-1 immunoglobulin heavy variable 1/OR21-1 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:10,649,390...10,649,835
Ensembl chr21:10,649,400...10,649,835
JBrowse link
G IGHV2-26 immunoglobulin heavy variable 2-26 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,301,395...106,301,838
Ensembl chr14:106,301,396...106,301,862
JBrowse link
G IGHV2-5 immunoglobulin heavy variable 2-5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,037,902...106,038,345
Ensembl chr14:106,037,902...106,038,365
JBrowse link
G IGHV2-70 immunoglobulin heavy variable 2-70 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,770,577...106,771,020
Ensembl chr14:106,770,577...106,771,020
JBrowse link
G IGHV2-70D immunoglobulin heavy variable 2-70D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,723,574...106,724,017
Ensembl chr14:106,723,574...106,724,093
JBrowse link
G IGHV2OR16-5 immunoglobulin heavy variable 2/OR16-5 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:32,847,713...32,848,254
Ensembl chr16:32,847,713...32,848,156
JBrowse link
G IGHV3-11 immunoglobulin heavy variable 3-11 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,116,635...106,117,084
Ensembl chr14:106,116,635...106,117,204
JBrowse link
G IGHV3-13 immunoglobulin heavy variable 3-13 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,129,540...106,129,992
Ensembl chr14:106,129,540...106,130,072
JBrowse link
G IGHV3-15 immunoglobulin heavy variable 3-15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,153,622...106,154,083
Ensembl chr14:106,153,624...106,154,163
JBrowse link
G IGHV3-16 immunoglobulin heavy variable 3-16 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,165,203...106,165,656
Ensembl chr14:106,165,205...106,165,730
JBrowse link
G IGHV3-20 immunoglobulin heavy variable 3-20 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,210,936...106,211,391
Ensembl chr14:106,210,936...106,211,453
JBrowse link
G IGHV3-21 immunoglobulin heavy variable 3-21 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,235,062...106,235,515
Ensembl chr14:106,235,064...106,235,594
JBrowse link
G IGHV3-23 immunoglobulin heavy variable 3-23 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,268,606...106,269,061
Ensembl chr14:106,268,606...106,269,140
JBrowse link
G IGHV3-30 immunoglobulin heavy variable 3-30 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,335,080...106,335,533
Ensembl chr14:106,335,082...106,335,613
JBrowse link
G IGHV3-30-3 immunoglobulin heavy variable 3-30-3 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3-30-5 immunoglobulin heavy variable 3-30-5 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3-33 immunoglobulin heavy variable 3-33 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,359,791...106,360,244
Ensembl chr14:106,359,793...106,360,324
JBrowse link
G IGHV3-35 immunoglobulin heavy variable 3-35 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,389,390...106,389,843
Ensembl chr14:106,389,392...106,389,858
JBrowse link
G IGHV3-38 immunoglobulin heavy variable 3-38 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,410,494...106,410,943
Ensembl chr14:106,410,493...106,411,021
JBrowse link
G IGHV3-43 immunoglobulin heavy variable 3-43 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,470,263...106,470,720
Ensembl chr14:106,470,264...106,470,800
JBrowse link
G IGHV3-48 immunoglobulin heavy variable 3-48 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,537,810...106,538,265
Ensembl chr14:106,537,810...106,538,344
JBrowse link
G IGHV3-49 immunoglobulin heavy variable 3-49 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,556,936...106,557,397
Ensembl chr14:106,556,936...106,557,477
JBrowse link
G IGHV3-53 immunoglobulin heavy variable 3-53 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,592,676...106,593,126
Ensembl chr14:106,592,676...106,593,347
JBrowse link
G IGHV3-64 immunoglobulin heavy variable 3-64 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,657,723...106,658,178
Ensembl chr14:106,657,725...106,658,258
JBrowse link
G IGHV3-64D immunoglobulin heavy variable 3-64D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,088,122...106,088,573
Ensembl chr14:106,088,122...106,088,573
JBrowse link
G IGHV3-66 immunoglobulin heavy variable 3-66 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,675,015...106,675,465
Ensembl chr14:106,675,017...106,675,544
JBrowse link
G IGHV3-7 immunoglobulin heavy variable 3-7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,062,149...106,062,604
Ensembl chr14:106,062,151...106,062,683
JBrowse link
G IGHV3-72 immunoglobulin heavy variable 3-72 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,790,692...106,791,153
Ensembl chr14:106,790,691...106,791,233
JBrowse link
G IGHV3-73 immunoglobulin heavy variable 3-73 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,802,692...106,803,153
Ensembl chr14:106,802,694...106,803,233
JBrowse link
G IGHV3-74 immunoglobulin heavy variable 3-74 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,810,440...106,810,895
Ensembl chr14:106,810,442...106,811,131
JBrowse link
G IGHV3-9 immunoglobulin heavy variable 3-9 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3OR15-7 immunoglobulin heavy variable 3/OR15-7 (pseudogene) IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:19,987,656...19,988,117 JBrowse link
G IGHV3OR16-10 immunoglobulin heavy variable 3/OR16-10 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:32,995,213...32,995,503
Ensembl chr16:32,995,048...32,995,505
JBrowse link
G IGHV3OR16-12 immunoglobulin heavy variable 3/OR16-12 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,802,922...33,803,215
Ensembl chr16:33,802,764...33,803,217
JBrowse link
G IGHV3OR16-13 immunoglobulin heavy variable 3/OR16-13 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,827,366...33,827,659
Ensembl chr16:33,827,214...33,827,661
JBrowse link
G IGHV3OR16-17 immunoglobulin heavy variable 3/OR16-17 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,844,758...33,845,274
Ensembl chr16:33,844,784...33,845,229
JBrowse link
G IGHV3OR16-8 immunoglobulin heavy variable 3/OR16-8 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,009,124...33,009,646
Ensembl chr16:33,009,175...33,009,620
JBrowse link
G IGHV3OR16-9 immunoglobulin heavy variable 3/OR16-9 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:32,066,065...32,066,358
Ensembl chr16:32,066,065...32,066,358
JBrowse link
G IGHV4-28 immunoglobulin heavy variable 4-28 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,324,254...106,324,688
Ensembl chr14:106,324,254...106,324,760
JBrowse link
G IGHV4-30-2 immunoglobulin heavy variable 4-30-2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,349,283...106,349,720 JBrowse link
G IGHV4-30-4 immunoglobulin heavy variable 4-30-4 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV4-31 immunoglobulin heavy variable 4-31 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,349,283...106,349,720
Ensembl chr14:106,349,283...106,349,792
JBrowse link
G IGHV4-34 immunoglobulin heavy variable 4-34 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,373,661...106,374,093
Ensembl chr14:106,373,663...106,374,145
JBrowse link
G IGHV4-38-2 immunoglobulin heavy variable 4-38-2 IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV4-39 immunoglobulin heavy variable 4-39 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,421,709...106,422,147
Ensembl chr14:106,421,711...106,422,218
JBrowse link
G IGHV4-4 immunoglobulin heavy variable 4-4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,011,922...106,012,356
Ensembl chr14:106,011,922...106,012,420
JBrowse link
G IGHV4-59 immunoglobulin heavy variable 4-59 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,627,249...106,627,680
Ensembl chr14:106,627,249...106,627,825
JBrowse link
G IGHV4-61 immunoglobulin heavy variable 4-61 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,639,119...106,639,556
Ensembl chr14:106,639,119...106,639,657
JBrowse link
G IGHV4OR15-8 immunoglobulin heavy variable 4/OR15-8 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:22,184,967...22,185,402 JBrowse link
G IGHV5-10-1 immunoglobulin heavy variable 5-10-1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,107,972...106,108,513
Ensembl chr14:106,107,972...106,108,464
JBrowse link
G IGHV5-51 immunoglobulin heavy variable 5-51 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,578,742...106,579,177
Ensembl chr14:106,578,744...106,579,236
JBrowse link
G IGHV6-1 immunoglobulin heavy variable 6-1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,939,754...105,940,201
Ensembl chr14:105,939,756...105,940,253
JBrowse link
G IGHV7-4-1 immunoglobulin heavy variable 7-4-1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,025,145...106,025,581
Ensembl chr14:106,025,145...106,025,630
JBrowse link
G IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,874,581...106,875,017
Ensembl chr14:106,874,583...106,875,071
JBrowse link
G IGKC immunoglobulin kappa constant IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:88,857,361...88,857,683
Ensembl chr 2:88,857,161...88,857,683
JBrowse link
G IGLC1 immunoglobulin lambda constant 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,895,375...22,895,694
Ensembl chr22:22,895,375...22,895,834
JBrowse link
G IGLC2 immunoglobulin lambda constant 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,900,976...22,901,295
Ensembl chr22:22,900,976...22,901,437
JBrowse link
G IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,906,342...22,906,661
Ensembl chr22:22,906,342...22,906,803
JBrowse link
G IGLC6 immunoglobulin lambda constant 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,919,535...22,919,858
Ensembl chr22:22,919,535...22,919,851
JBrowse link
G IGLC7 immunoglobulin lambda constant 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,922,594...22,922,913
Ensembl chr22:22,922,594...22,923,034
JBrowse link
G IGLL1 immunoglobulin lambda like polypeptide 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:23,573,125...23,580,290
Ensembl chr22:23,573,125...23,580,302
JBrowse link
G IGLL5 immunoglobulin lambda like polypeptide 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,887,816...22,896,111
Ensembl chr22:22,887,780...22,896,111
JBrowse link
G ITK IL2 inducible T cell kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:157,180,840...157,255,185
Ensembl chr 5:157,142,933...157,255,191
Ensembl chr 5:157,142,933...157,255,191
JBrowse link
G KLHL6 kelch like family member 6 IEA Ensembl
InterPro
GO_REF:0000002, GO_REF:0000107 NCBI chr 3:183,487,551...183,555,711
Ensembl chr 3:183,487,551...183,555,706
JBrowse link
G LAT2 linker for activation of T cells family member 2 IDA (PMID:12514734) HGNC PMID:12514734 NCBI chr 7:74,210,006...74,229,834
Ensembl chr 7:74,199,652...74,229,834
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,239...32,286,165
JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 8:55,876,041...56,014,169
Ensembl chr 8:55,879,835...56,014,169
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MEF2C myocyte enhancer factor 2C ISS UniProtKB GO_REF:0000024 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257
JBrowse link
G MNDA myeloid cell nuclear differentiation antigen IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr 1:158,831,351...158,849,502
Ensembl chr 1:158,831,351...158,849,506
JBrowse link
G MS4A1 membrane spanning 4-domains A1 IDA (PMID:18474602) UniProt PMID:18474602 NCBI chr11:60,455,847...60,470,752
Ensembl chr11:60,455,752...60,470,760
Ensembl chr11:60,455,752...60,470,760
JBrowse link
G NCKAP1L NCK associated protein 1 like IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:42,380,407...42,437,986
Ensembl chr22:42,380,407...42,432,403
Ensembl chr22:42,380,407...42,432,403
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr20:51,386,963...51,562,857
Ensembl chr20:51,386,957...51,562,831
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta TAS (PMID:20940048) UniProtKB PMID:20940048 NCBI chr 1:9,629,889...9,729,114
Ensembl chr 1:9,651,731...9,729,114
JBrowse link
G PLCG2 phospholipase C gamma 2 ISS UniProtKB GO_REF:0000024 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,739,097...81,962,685
JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 IDA (PMID:12101241) UniProtKB PMID:12101241 NCBI chr10:122,374,675...122,442,600
Ensembl chr10:122,374,696...122,442,602
JBrowse link
G PRKCB protein kinase C beta ISS UniProtKB GO_REF:0000024 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 IEA Ensembl GO_REF:0000107 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C ISS UniProtKB GO_REF:0000024 NCBI chr 1:198,639,025...198,757,476
Ensembl chr 1:198,638,457...198,757,476
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 IMP (PMID:12805216) UniProtKB PMID:12805216 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026
JBrowse link
G SH2B2 SH2B adaptor protein 2 IDA (PMID:9233773) UniProt PMID:9233773 NCBI chr 7:102,284,525...102,321,711
Ensembl chr 7:102,285,091...102,321,711
JBrowse link
G SYK spleen associated tyrosine kinase ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G TEC tec protein tyrosine kinase IDA
IBA
(PMID:10518561)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10518561, PMID:21873635 NCBI chr 4:48,135,783...48,269,864
Ensembl chr 4:48,135,783...48,269,838
JBrowse link
G TRBC1 T cell receptor beta constant 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,791,694...142,793,141
Ensembl chr 7:142,791,694...142,793,368
JBrowse link
G TRBC2 T cell receptor beta constant 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,801,041...142,802,529
Ensembl chr 7:142,801,041...142,802,748
JBrowse link
G TRDC T cell receptor delta constant IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:22,462,932...22,466,577
Ensembl chr14:22,462,932...22,465,787
JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 IMP (PMID:17875758) UniProtKB PMID:17875758 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator IDA (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule TAS
IBA
IDA
IMP
(PMID:15240561)
(PMID:21873635)
(PMID:26017478)
(PMID:24169826)
ARUK-UCL
GO_Central
PMID:15240561, PMID:21873635, PMID:24169826, PMID:26017478 NCBI chr19:35,329,187...35,347,361
Ensembl chr19:35,319,261...35,347,361
JBrowse link
G CD300A CD300a molecule IDA (PMID:21482706) UniProtKB PMID:21482706 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,794
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb IMP (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,147...161,678,654
JBrowse link
G FCRL3 Fc receptor like 3 IDA (PMID:19843936) UniProtKB PMID:19843936 NCBI chr 1:157,676,481...157,700,985
Ensembl chr 1:157,674,321...157,700,769
JBrowse link
G FCRL5 Fc receptor like 5 ISO (MGI:MGI:5471851|PMID:23509253) MGI PMID:23509253 MGI:MGI:5471851 NCBI chr 1:157,513,377...157,552,533
Ensembl chr 1:157,513,377...157,552,515
JBrowse link
G GPS2 G protein pathway suppressor 2 ISS UniProtKB GO_REF:0000024 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564
JBrowse link
G LPXN leupaxin IDA
IBA
(PMID:17640867)
(PMID:21873635)
UniProtKB
GO_Central
PMID:17640867, PMID:21873635 NCBI chr11:58,526,871...58,578,239
Ensembl chr11:58,526,871...58,578,220
JBrowse link
G PLCL2 phospholipase C like 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:16,802,691...17,090,606
Ensembl chr 3:16,802,651...17,090,604
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule ISS
IMP
(PMID:20237408) UniProt PMID:20237408 GO_REF:0000024 NCBI chr11:2,376,180...2,397,402
Ensembl chr11:2,376,177...2,397,419
Ensembl chr11:2,376,177...2,397,419
JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 IEA Ensembl GO_REF:0000107 NCBI chr16:66,603,996...66,613,892
Ensembl chr16:66,603,874...66,613,892
JBrowse link
G FOXP1 forkhead box P1 IMP (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr 3:70,954,708...71,583,983
Ensembl chr 3:70,952,817...71,583,993
Ensembl chr 3:70,952,817...71,583,993
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 IEA
ISS
(PMID:15143214) InterPro
HGNC
PMID:15143214 GO_REF:0000002 NCBI chr22:42,380,407...42,437,986
Ensembl chr22:42,380,407...42,432,403
Ensembl chr22:42,380,407...42,432,403
JBrowse link
G PRKCB protein kinase C beta ISS UniProtKB GO_REF:0000024 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCH protein kinase C eta IMP (PMID:18780722) UniProtKB PMID:18780722 NCBI chr14:61,187,305...61,550,980
Ensembl chr14:61,187,559...61,550,976
JBrowse link
G SLC39A10 solute carrier family 39 member 10 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:195,575,944...195,737,701
Ensembl chr 2:195,575,977...195,737,702
JBrowse link
G STAP1 signal transducing adaptor family member 1 IDA (PMID:10518561) BHF-UCL PMID:10518561 NCBI chr 4:67,558,727...67,607,337
Ensembl chr 4:67,558,727...67,607,337
JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-8939245 NCBI chr 8:11,493,991...11,564,599
Ensembl chr 8:11,486,894...11,564,599
JBrowse link
G CBFB core-binding factor subunit beta TAS Reactome Reactome:R-HSA-8939245 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G CD19 CD19 molecule IMP (PMID:9382888) UniProt PMID:9382888 NCBI chr16:28,931,735...28,939,347
Ensembl chr16:28,931,965...28,939,342
Ensembl chr16:28,931,965...28,939,342
JBrowse link
G ELF1 E74 like ETS transcription factor 1 TAS Reactome Reactome:R-HSA-8939245 NCBI chr13:40,931,919...41,061,386
Ensembl chr13:40,931,924...41,061,440
JBrowse link
G ELF2 E74 like ETS transcription factor 2 TAS Reactome Reactome:R-HSA-8939245 NCBI chr 4:139,057,220...139,177,218
Ensembl chr 4:139,028,112...139,177,218
JBrowse link
G GCSAM germinal center associated signaling and motility IEA
IBA
IMP
(PMID:21873635)
(PMID:23299888)
InterPro
GO_Central
UniProtKB
PMID:21873635, PMID:23299888 GO_REF:0000002 NCBI chr 3:112,120,839...112,133,956
Ensembl chr 3:112,120,839...112,133,270
JBrowse link
G GCSAML germinal center associated signaling and motility like IEA InterPro GO_REF:0000002 NCBI chr 1:247,507,058...247,577,690
Ensembl chr 1:247,507,058...247,577,690
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 8:55,876,041...56,014,169
Ensembl chr 8:55,879,835...56,014,169
JBrowse link
G PAX5 paired box 5 TAS Reactome Reactome:R-HSA-8939245 NCBI chr 9:36,833,269...37,034,268
Ensembl chr 9:36,833,269...37,034,268
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 NAS (PMID:19265110) BHF-UCL PMID:19265110 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RUNX1 RUNX family transcription factor 1 TAS Reactome Reactome:R-HSA-8939245 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    immune system process 3567
      activation of immune response 608
        immune response-activating signal transduction 513
          immune response-activating cell surface receptor signaling pathway 512
            antigen receptor-mediated signaling pathway 351
              B cell receptor signaling pathway 149
                B cell receptor apoptotic signaling pathway 1
                negative regulation of B cell receptor signaling pathway 8
                positive regulation of B cell receptor signaling pathway 8
                regulation of B cell receptor signaling pathway + 27
Path 2
Term Annotations click to browse term
  biological_process 18650
    biological regulation 13283
      regulation of biological process 12625
        positive regulation of biological process 6978
          positive regulation of immune system process 1220
            positive regulation of immune response 838
              activation of immune response 608
                immune response-activating signal transduction 513
                  immune response-activating cell surface receptor signaling pathway 512
                    antigen receptor-mediated signaling pathway 351
                      B cell receptor signaling pathway 149
                        B cell receptor apoptotic signaling pathway 1
                        negative regulation of B cell receptor signaling pathway 8
                        positive regulation of B cell receptor signaling pathway 8
                        regulation of B cell receptor signaling pathway + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.