Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:T cell receptor signaling pathway
go back to main search page
Accession:GO:0050852 term browser browse the term
Definition:The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms:exact_synonym: T lymphocyte receptor signaling pathway;   T lymphocyte receptor signalling pathway;   T-cell receptor signalling pathway;   TCR signaling pathway



show annotations for term's descendants           Sort by:
 
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049499.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:119,677,204...119,800,910 JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) RGD PMID:18305217 MGI:3798766 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ada adenosine deaminase acts_upstream_of ISO MGI:1857117|MGI:2683027 (MGI:3640996|PMID:11435465) RGD PMID:11435465 MGI:3640996 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:15125833)
UniProt
RGD
PMID:15125833 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3773982|PMID:18228248) RGD PMID:18228248 MGI:3773982 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,654,237...41,663,427
Ensembl chr17:41,654,249...41,664,272
JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
JBrowse link
G Btn3a2 butyrophilin, subfamily 3, member A2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,398,254...4,405,681
Ensembl chr20:4,398,254...4,405,681
JBrowse link
G Btnl10 butyrophilin like 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:43,694,083...43,701,800
Ensembl chr10:43,694,073...43,700,926
JBrowse link
G Btnl2 butyrophilin-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,490,904...4,502,557
Ensembl chr20:4,489,517...4,503,341
JBrowse link
G Btnl3 butyrophilin-like 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,474,056...4,489,024
Ensembl chr20:4,474,056...4,489,024
JBrowse link
G Btnl5 butyrophilin-like 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385
JBrowse link
G Btnl7 butyrophilin-like 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,301,078...4,313,522
Ensembl chr20:4,301,854...4,313,274
JBrowse link
G Btnl8 butyrophilin-like 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,266,794...4,280,876
Ensembl chr20:4,266,794...4,408,167
JBrowse link
G Btnl9 butyrophilin-like 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO MGI:2389248 (MGI:3691409|PMID:17028169) RGD PMID:17028169 MGI:3691409 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO MGI:1856936 (MGI:3526783|PMID:15637280), (MGI:3691409|PMID:17028169) RGD PMID:15637280 PMID:17028169 MGI:3526783 MGI:3691409 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO MGI:5547539 (MGI:5544872|PMID:23793062) RGD PMID:23793062 MGI:5544872 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2665211|PMID:12697763)
Ensembl
RGD
PMID:12697763 GO_REF:0000107 MGI:2665211 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cd247 Cd247 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3640996|PMID:11435465)
RGD PMID:11435465 PMID:21873635 MGI:3640996, RGD:13792537 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd276 Cd276 molecule involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cd28 Cd28 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857150 (MGI:5544872|PMID:23793062)
RGD PMID:23793062 PMID:21873635 MGI:5544872, RGD:13792537 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (MGI:3577956|PMID:10485657) RGD PMID:10485657 MGI:3577956 NCBI chr 8:45,303,848...45,315,297
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd8a CD8a molecule involved_in ISO (PMID:17145893) RGD PMID:17145893 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
JBrowse link
G Cd8b CD8b molecule involved_in ISO (PMID:17145893) RGD PMID:17145893 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Clec2dl1 C-type lectin domain family 2 member D-like 1 acts_upstream_of_or_within ISO (MGI:3622591|PMID:16143319) RGD PMID:16143319 MGI:3622591 NCBI chr 4:162,263,578...162,274,882
Ensembl chr 4:162,263,639...162,274,880
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (MGI:3798766|PMID:18305217) RGD PMID:18305217 MGI:3798766 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Dennd1b DENN domain containing 1B involved_in IBA
ISO
PMID:21873635
(MGI:5751612|PMID:26774822)
(PMID:26774822)
RGD PMID:26774822 PMID:21873635 MGI:5751612, RGD:13792537 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO
IEA
ISS
(PMID:8626696)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:8626696)
Ensembl
UniProt
RGD
PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO
ISS
(PMID:8626696)
GO_REF:0000024
RGD
UniProt
PMID:8626696 GO_REF:0000024 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISS
ISO
GO_REF:0000024
(PMID:8626696)
UniProt
RGD
PMID:8626696 GO_REF:0000024 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISS
ISO
GO_REF:0000024
(PMID:8626696)
UniProt
RGD
PMID:8626696 GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419
JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in ISO (PMID:32098969) RGD PMID:32098969 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034 (MGI:1331533|PMID:10072494), (MGI:1929588|PMID:11265635) RGD PMID:10072494 PMID:11265635 MGI:1331533 MGI:1929588 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fyb1 FYN binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO
IBA
(PMID:27335501)
PMID:21873635
RGD PMID:27335501 PMID:21873635 RGD:13792537 NCBI chr 5:119,677,116...119,800,911
Ensembl chr 5:119,677,204...119,800,910
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IBA
(PMID:7722293)
PMID:21873635
RGD PMID:7722293 PMID:21873635 RGD:13792537 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285154|PMID:20696860)
UniProt
RGD
PMID:20696860 GO_REF:0000024 MGI:5285154 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:2385945 (MGI:5013687|PMID:21444916) RGD PMID:21444916 MGI:5013687 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Icoslg inducible T-cell co-stimulator ligand involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) RGD PMID:21444916 MGI:5013687 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Itk IL2-inducible T-cell kinase involved_in IBA
ISO
PMID:21873635
(MGI:1335923|PMID:10213685)
RGD PMID:10213685 PMID:21873635 MGI:1335923, RGD:13792537 NCBI chr10:30,753,339...30,814,685
Ensembl chr10:30,753,344...30,814,685
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO (PMID:9045636) RGD PMID:9045636 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) RGD PMID:20551903 NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559
JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127
JBrowse link
G LOC100911938 butyrophilin subfamily 3 member A3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G LOC689599 hypothetical protein LOC689599 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:106,543,112...106,580,780
Ensembl chr 9:106,543,723...106,580,907
JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO
IBA
(PMID:15125833)
(MGI:6142401|PMID:25282160)
PMID:21873635
RGD PMID:15125833 PMID:25282160 PMID:21873635 MGI:6142401, RGD:13792537 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) RGD PMID:9064344 MGI:82729 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mog myelin oligodendrocyte glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:2385944 (MGI:5013687|PMID:21444916) RGD PMID:21444916 MGI:5013687 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (PMID:17404263) RGD PMID:17404263 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (PMID:17404263) RGD PMID:17404263 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Plcg1 phospholipase C, gamma 1 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) RGD PMID:15728238 MGI:3531056 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3531056|PMID:15728238)
Ensembl
RGD
PMID:15728238 GO_REF:0000107 MGI:3531056 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Pram1 PML-RARA regulated adaptor molecule 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:14,428,548...14,438,081
Ensembl chr 7:14,420,165...14,438,166
JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:17077180) RGD PMID:17077180 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:3760494|PMID:17698590) RGD PMID:17698590 MGI:3760494 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:3760494|PMID:17698590) RGD PMID:17698590 MGI:3760494 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3043469 (MGI:3042327|PMID:14752163)
RGD PMID:14752163 PMID:21873635 MGI:3042327, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of
involved_in
ISO
IEA
MGI:1856074 (MGI:82729|PMID:9064344)
GO_REF:0000107
RGD
Ensembl
PMID:9064344 GO_REF:0000107 MGI:82729 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in IGI
ISO
ISS
PMID:12496963
UniProtKB:P04157 (MGI:6201809|PMID:12496963)
GO_REF:0000024
(PMID:10358156)
RGD
UniProt
PMID:10358156 PMID:12496963 PMID:12496963 GO_REF:0000024 MGI:6201809, RGD:1358565 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO
IEA
(PMID:20005846)
GO_REF:0000107
RGD
Ensembl
PMID:20005846 GO_REF:0000107 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) RGD PMID:19414744 MGI:3850290 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084
JBrowse link
G RGD1624210 similar to butyrophilin-like 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,231,350...4,244,825
Ensembl chr20:4,235,141...4,244,690
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of_or_within
ISO (MGI:5285496|PMID:21469090)
MGI:2660793 (MGI:2176422|PMID:11894098)
RGD PMID:11894098 PMID:21469090 MGI:2176422 MGI:5285496 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:20005846) RGD PMID:20005846 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
JBrowse link
G RT1-Bb RT1 class II, locus Bb involved_in ISO (PMID:32341563) RGD PMID:32341563 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:32341563) RGD PMID:32341563 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO MGI:3721903 (MGI:5617929|PMID:24645804) RGD PMID:24645804 MGI:5617929 NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538
JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) RGD PMID:11909961 NCBI chr10:81,425,472...81,732,651
Ensembl chr10:81,425,525...81,732,650
JBrowse link
G Skint1 selection and upkeep of intraepithelial T cells 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:126,786,469...126,814,599
Ensembl chr 5:126,786,469...126,814,720
JBrowse link
G Skint10 selection and upkeep of intraepithelial T cells 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:127,769,022...127,811,541
Ensembl chr 5:127,769,052...127,847,189
JBrowse link
G Skint4 selection and upkeep of intraepithelial T cells 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:126,878,834...126,909,044
Ensembl chr 5:126,875,682...126,913,167
JBrowse link
G Skint8 selection and upkeep of intraepithelial T cells 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:126,764,502...126,773,125
Ensembl chr 5:126,751,394...126,773,247
JBrowse link
G Spn sialophorin involved_in IGI PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971)
(MGI:5640905|PMID:25384971)
RGD PMID:25384971 MGI:5640905 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126
JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO MGI:2387402|MGI:3054844|MGI:96756 (MGI:5003385|PMID:21487392) RGD PMID:21487392 MGI:5003385 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Stoml2 stomatin like 2 involved_in ISO
ISS
(PMID:18641330)
GO_REF:0000024
RGD
UniProt
PMID:18641330 GO_REF:0000024 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920
JBrowse link
G Tec tec protein tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
JBrowse link
G Themis thymocyte selection associated involved_in IBA
ISO
PMID:21873635
(MGI:4352756|PMID:19597499), (MGI:4352757|PMID:19597498)
RGD PMID:19597498 PMID:19597499 PMID:21873635 MGI:4352756 MGI:4352757, RGD:13792537 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329
JBrowse link
G Themis2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5446993|PMID:22732588)
RGD PMID:22732588 PMID:21873635 MGI:5446993, RGD:13792537 NCBI chr 5:144,991,110...145,006,347
Ensembl chr 5:144,991,112...145,006,400
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IBA
IMP
PMID:21873635
PMID:9285719
GO_Central
UniProt
PMID:21873635 PMID:9285719 RGD:13792537, RGD:8554466 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:2137821|PMID:11485735)
UniProt
RGD
PMID:11485735 GO_REF:0000024 MGI:2137821 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Txk TXK tyrosine kinase involved_in IBA
ISO
PMID:21873635
(MGI:1335923|PMID:10213685)
RGD PMID:10213685 PMID:21873635 MGI:1335923, RGD:13792537 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) RGD PMID:27400149 MGI:6141968 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:3526403 (MGI:893249|PMID:9208839) RGD PMID:9208839 MGI:893249 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:5706909|PMID:23185455), (MGI:6142401|PMID:25282160)
UniProt
RGD
PMID:23185455 PMID:25282160 GO_REF:0000024 MGI:5706909 MGI:6142401 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:26179882) RGD PMID:26179882 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07035561.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:17,364,080...17,365,280 JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) RGD PMID:23589618 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
JBrowse link
G Btnl2 butyrophilin-like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3775536|PMID:16751379)
Ensembl
RGD
PMID:16751379 GO_REF:0000107 MGI:3775536 NCBI chr20:4,490,904...4,502,557
Ensembl chr20:4,489,517...4,503,341
JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180572 (MGI:3041371|PMID:14738763)
Ensembl
RGD
PMID:14738763 GO_REF:0000107 MGI:3041371 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) RGD PMID:18193050 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISS
ISO
GO_REF:0000024
(MGI:2672999|PMID:12883552)
UniProt
RGD
PMID:12883552 GO_REF:0000024 MGI:2672999 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) RGD PMID:24714587 MGI:5583944 NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IBA
ISO
PMID:21873635
(PMID:12447358)
RGD PMID:12447358 PMID:21873635 RGD:13792537 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO MGI:1926074 (MGI:3041371|PMID:14738763) RGD PMID:14738763 MGI:3041371 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) RGD PMID:20551903 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) RGD PMID:19706535 MGI:4355752 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035), (PMID:22387553) RGD PMID:16493035 PMID:22387553 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (MGI:2675524|PMID:12970181) RGD PMID:12970181 MGI:2675524 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) RGD PMID:18796614 NCBI chr 3:8,392,926...8,394,325 JBrowse link
G Prnp prion protein involved_in ISO (MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:4943618 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5320871|PMID:22080863)
UniProt
RGD
PMID:22080863 GO_REF:0000024 MGI:5320871 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:18056643) RGD PMID:18056643 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856074 (MGI:82729|PMID:9064344)
Ensembl
RGD
PMID:9064344 GO_REF:0000107 MGI:82729 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:11259588), (PMID:12913111), (PMID:9780142)
(MGI:4942249|PMID:12913111)
RGD PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO
IBA
(PMID:26755705)
PMID:21873635
RGD PMID:26755705 PMID:21873635 RGD:13792537 NCBI chr12:17,363,721...17,365,577
Ensembl chr12:17,364,080...17,365,280
JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) RGD PMID:9774102 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sla2 Src-like-adaptor 2 involved_in ISO (PMID:11891219) RGD PMID:11891219 NCBI chr 3:145,367,070...145,383,586
Ensembl chr 3:145,368,598...145,382,480
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISS
ISO
GO_REF:0000024
(MGI:1096761|PMID:9285719)
UniProt
RGD
PMID:9285719 GO_REF:0000024 MGI:1096761 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:107180 (MGI:3041371|PMID:14738763)
RGD PMID:14738763 PMID:21873635 MGI:3041371, RGD:13792537 NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224
JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3640996|PMID:11435465) RGD PMID:11435465 MGI:3640996 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:18287044), (PMID:27777308)
UniProt
RGD
PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)
RGD PMID:12154356 PMID:12154360 MGI:6695669 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) RGD PMID:17785582 MGI:3847607 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:26755705)
PMID:21873635
RGD PMID:26755705 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Cd81 Cd81 molecule involved_in ISO
ISS
(PMID:23858057)
GO_REF:0000024
RGD
UniProt
PMID:23858057 GO_REF:0000024 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO MGI:3664438 (MGI:3656194|PMID:16501569) RGD PMID:16501569 MGI:3656194 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISS
ISO
GO_REF:0000024
(PMID:18287044), (PMID:27777308)
UniProt
RGD
PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO
IEA
(PMID:18796614)
GO_REF:0000107
RGD
Ensembl
PMID:18796614 GO_REF:0000107 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:26755705)
PMID:21873635
RGD PMID:26755705 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO
GO_REF:0000024
(MGI:4849903|PMID:20819079)
UniProt
RGD
PMID:20819079 GO_REF:0000024 MGI:4849903 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) RGD PMID:26021297 NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:11390434)
PMID:21873635
RGD PMID:11390434 PMID:21873635 RGD:13792537 NCBI chr11:52,035,750...52,077,805
Ensembl chr11:52,035,750...52,077,805
JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10, immune signaling adaptor acts_upstream_of_or_within ISO MGI:2158304 (MGI:3629264|PMID:14614861) RGD PMID:14614861 MGI:3629264 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:22046970) RGD PMID:22046970 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) RGD PMID:14752163 MGI:3042327 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO MGI:3639305 (MGI:3629264|PMID:14614861) RGD PMID:14614861 MGI:3629264 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) RGD PMID:15917799 MGI:3580753 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    immune system process 2730
      activation of immune response 340
        immune response-activating signal transduction 261
          immune response-activating cell surface receptor signaling pathway 260
            antigen receptor-mediated signaling pathway 213
              T cell receptor signaling pathway 134
                negative regulation of T cell receptor signaling pathway + 27
                positive regulation of T cell receptor signaling pathway 15
                regulation of T cell receptor signaling pathway + 46
                termination of T cell signal transduction 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        positive regulation of biological process 6662
          positive regulation of immune system process 962
            positive regulation of immune response 568
              activation of immune response 340
                immune response-activating signal transduction 261
                  immune response-activating cell surface receptor signaling pathway 260
                    antigen receptor-mediated signaling pathway 213
                      T cell receptor signaling pathway 134
                        negative regulation of T cell receptor signaling pathway + 27
                        positive regulation of T cell receptor signaling pathway 15
                        regulation of T cell receptor signaling pathway + 46
                        termination of T cell signal transduction 0
paths to the root