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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of calcium-mediated signaling
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Accession:GO:0050850 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.
Synonyms:exact_synonym: positive regulation of calcium-mediated signalling;   up regulation of calcium-mediated signaling;   upregulation of calcium-mediated signaling
 narrow_synonym: activation of calcium-mediated signaling;   stimulation of calcium-mediated signaling


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positive regulation of calcium-mediated signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO (MGI:MGI:3640996|PMID:11435465) RGD PMID:11435465 MGI:MGI:3640996 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:MGI:2155986 (MGI:MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO
ISS
(PMID:10679098)
GO_REF:0000024
RGD
UniProt
PMID:10679098 GO_REF:0000024 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO (PMID:10679098) RGD PMID:10679098 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Cd24 CD24 molecule ISO (MGI:MGI:3757623|PMID:8117278), (MGI:MGI:74049|PMID:7613634) RGD PMID:7613634, PMID:8117278 MGI:MGI:3757623, MGI:MGI:74049 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd3e CD3e molecule ISO (MGI:MGI:3757616|PMID:8943715), (MGI:MGI:75253|PMID:7630421) RGD PMID:7630421, PMID:8943715 MGI:MGI:3757616, MGI:MGI:75253 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd4 Cd4 molecule ISO (MGI:MGI:893249|PMID:9208839) RGD PMID:9208839 MGI:MGI:893249 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd8a CD8a molecule ISO (MGI:MGI:893249|PMID:9208839) RGD PMID:9208839 MGI:MGI:893249 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cdh13 cadherin 13 ISO (PMID:16013438) RGD PMID:16013438 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Exoc4 exocyst complex component 4 IMP RGD PMID:10973998 RGD:2314429 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 ISO (MGI:MGI:5512789|PMID:23576580) RGD PMID:23576580 MGI:MGI:5512789 NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
JBrowse link
G Itgal integrin subunit alpha L ISO (MGI:MGI:3757623|PMID:8117278) RGD PMID:8117278 MGI:MGI:3757623 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18221855 RGD:2292019 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G L1cam L1 cell adhesion molecule ISO (MGI:MGI:74049|PMID:7613634) RGD PMID:7613634 MGI:MGI:74049 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8187959 RGD:2292619 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO (MGI:MGI:74049|PMID:7613634) RGD PMID:7613634 MGI:MGI:74049 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Neurod2 neuronal differentiation 2 ISO
ISS
(MGI:MGI:3621523|PMID:16504944)
GO_REF:0000024
RGD
UniProt
PMID:16504944 GO_REF:0000024, MGI:MGI:3621523 NCBI chr10:86,280,865...86,282,681
Ensembl chr10:86,280,892...86,282,693
JBrowse link
G P2rx4 purinergic receptor P2X 4 ISO (PMID:10899068), (PMID:10969036) RGD PMID:10899068, PMID:10969036 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Syk spleen associated tyrosine kinase ISO
IEA
MGI:MGI:2384078 (MGI:MGI:85068|PMID:9000133)
GO_REF:0000107
RGD
Ensembl
PMID:9000133 GO_REF:0000107, MGI:MGI:85068 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 ISO (PMID:11390434) RGD PMID:11390434 NCBI chr11:54,619,169...54,661,284
Ensembl chr11:54,619,129...54,662,353
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 ISO (PMID:11602640) RGD PMID:11602640 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 ISO MGI:MGI:2677447|MGI:MGI:3526403 (MGI:MGI:75253|PMID:7630421), (MGI:MGI:893249|PMID:9208839) RGD PMID:7630421, PMID:9208839 MGI:MGI:75253, MGI:MGI:893249 NCBI chr 9:43,331,149...43,353,097
Ensembl chr 9:43,331,155...43,353,113
JBrowse link
positive regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 IMP PMID:22343722 UniProt PMID:22343722 RGD:13507305 NCBI chr 6:99,356,509...99,361,909
Ensembl chr 6:99,356,509...99,361,909
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP PMID:16306226 BHF-UCL PMID:16306226 RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Camta1 calmodulin binding transcription activator 1 ISO (PMID:23853098) RGD PMID:23853098 NCBI chr 5:168,138,207...169,017,295
Ensembl chr 5:168,141,372...169,017,295
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 ISO MGI:MGI:3053071|MGI:MGI:5609428 (MGI:MGI:5451119|PMID:23123061) RGD PMID:23123061 MGI:MGI:5451119 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cherp calcium homeostasis endoplasmic reticulum protein ISO (PMID:12656674) RGD PMID:12656674 NCBI chr16:19,068,783...19,081,837
Ensembl chr16:19,068,783...19,081,837
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 ISO
ISS
(PMID:18815128)
GO_REF:0000024
RGD
UniProt
PMID:18815128 GO_REF:0000024 NCBI chr 1:192,169,634...192,173,228
Ensembl chr 1:192,169,841...192,173,253
JBrowse link
G Cib1 calcium and integrin binding 1 ISO
IMP
(PMID:20639889)
(MGI:MGI:4821678|PMID:20639889)
RGD PMID:20639889, PMID:20639889 MGI:MGI:4821678, RGD:8554486 NCBI chr 1:142,014,962...142,020,461
Ensembl chr 1:142,014,958...142,020,525
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO
IEA
MGI:MGI:96083 (MGI:MGI:3830391|PMID:19179536)
GO_REF:0000107
RGD
Ensembl
PMID:19179536 GO_REF:0000107, MGI:MGI:3830391 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEA
(PMID:19654000)
GO_REF:0000107
RGD
Ensembl
PMID:19654000 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 ISO (PMID:20026769)
(MGI:MGI:4442539|PMID:20026769)
RGD PMID:20026769 MGI:MGI:4442539 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Nrg1 neuregulin 1 ISO
IEA
MGI:MGI:95411 (MGI:MGI:3830391|PMID:19179536)
GO_REF:0000107
RGD
Ensembl
PMID:19179536 GO_REF:0000107, MGI:MGI:3830391 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO
IEA
(PMID:23853098)
GO_REF:0000107
RGD
Ensembl
PMID:23853098 GO_REF:0000107 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G RGD1564899 similar to chromosome 10 open reading frame 71 IMP
ISO
PMID:28717008
(MGI:MGI:5917329|PMID:28717008)
RGD PMID:28717008, PMID:28717008 MGI:MGI:5917329, RGD:13602000 NCBI chr16:8,879,907...8,907,462
Ensembl chr16:8,881,138...8,885,797
JBrowse link
G Slc12a1 solute carrier family 12 member 1 ISO (MGI:MGI:4947009|PMID:21228109) RGD PMID:21228109 MGI:MGI:4947009 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO (PMID:22688515) RGD PMID:22688515 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Sppl3 signal peptide peptidase like 3 ISO (PMID:25384971)
(MGI:MGI:5640905|PMID:25384971)
RGD PMID:25384971 MGI:MGI:5640905 NCBI chr12:47,276,485...47,360,552
Ensembl chr12:47,276,476...47,360,507
JBrowse link
G Tmem110 transmembrane protein 110 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr16:6,903,212...6,958,786
Ensembl chr16:6,903,212...6,958,783
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:16803872) RGD PMID:16803872 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of CAMKK-AMPK signaling cascade term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:MGI:5906931|PMID:28802038) RGD PMID:28802038 MGI:MGI:5906931 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 IDA
IEA
ISO
PMID:12873381
GO_REF:0000107
(MGI:MGI:3603715|PMID:15379999)
Ensembl
RGD
PMID:15379999, PMID:12873381 GO_REF:0000107, MGI:MGI:3603715, RGD:6482800 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Htt huntingtin IEA
ISO
GO_REF:0000107
(PMID:12873381)
Ensembl
RGD
PMID:12873381 GO_REF:0000107 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 IMP PMID:17410128 ARUK-UCL PMID:17410128 RGD:13673830 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:16223735) RGD PMID:16223735 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 IDA PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Calm1 calmodulin 1 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO
IEA
(PMID:17023043)
GO_REF:0000107
RGD
Ensembl
PMID:17023043 GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO
IEA
(PMID:11035031)
GO_REF:0000107
RGD
Ensembl
PMID:11035031 GO_REF:0000107 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Jph2 junctophilin 2 ISO (PMID:20095964) RGD PMID:20095964 NCBI chr 3:159,709,998...159,776,536
Ensembl chr 3:159,712,325...159,775,643
JBrowse link
G Trdn triadin ISO
IBA
(PMID:15041652), (PMID:15731460)
PMID:21873635
RGD PMID:15041652, PMID:15731460, PMID:21873635 RGD:13792537 NCBI chr 1:25,403,390...25,787,664
Ensembl chr 1:25,403,390...25,839,345
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    signaling 7588
      positive regulation of signaling 2030
        positive regulation of signal transduction 1682
          positive regulation of intracellular signal transduction 1075
            positive regulation of calcium-mediated signaling 53
              positive regulation of CAMKK-AMPK signaling cascade 1
              positive regulation of calcineurin-mediated signaling + 18
              positive regulation of calcium-mediated signaling involved in cellular response to calcium ion 0
              positive regulation of calcium-mediated signaling involved in cellular response to salt stress 0
              positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
              positive regulation of ryanodine-sensitive calcium-release channel activity 9
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          signal transduction 7015
            intracellular signal transduction 2615
              second-messenger-mediated signaling 484
                calcium-mediated signaling 235
                  regulation of calcium-mediated signaling 109
                    positive regulation of calcium-mediated signaling 53
                      positive regulation of CAMKK-AMPK signaling cascade 1
                      positive regulation of calcineurin-mediated signaling + 18
                      positive regulation of calcium-mediated signaling involved in cellular response to calcium ion 0
                      positive regulation of calcium-mediated signaling involved in cellular response to salt stress 0
                      positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
                      positive regulation of ryanodine-sensitive calcium-release channel activity 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.