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ONTOLOGY REPORT - ANNOTATIONS

Term:defense response to Gram-negative bacterium
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Accession:GO:0050829 term browser browse the term
Definition:Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
Synonyms:exact_synonym: defence response to Gram-negative bacteria;   defence response to Gram-negative bacterium;   defense response to Gram-negative bacteria
 related_synonym: Gram-negative antibacterial peptide activity

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defense response to Gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO (MGI:4939876|PMID:21245295) UniProt PMID:21245295 MGI:4939876 NCBI chrNW_004955454:1,250,261...1,313,547
Ensembl chrNW_004955454:1,237,363...1,314,127 		JBrowse link
G App amyloid beta precursor protein involved_in ISO PMID:20209079 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) involved_in ISO (PMID:18665841)
(MGI:4457239|PMID:18665841)		 UniProt PMID:18665841 MGI:4457239 NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717 		JBrowse link
G Camp cathelicidin antimicrobial peptide acts_upstream_of_or_within
involved_in		 ISO (PMID:9148921)
(MGI:3770082|PMID:17012259)		 RGD
MGI
UniProt		 PMID:9148921 PMID:17012259 PMID:19879657 MGI:3770082 RGD:2316237 NCBI chrNW_004955420:24,911,920...24,914,698 JBrowse link
G Cd160 CD160 molecule acts_upstream_of_or_within ISO (PMID:22801499) MGI PMID:22801499 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Cd4 CD4 molecule acts_upstream_of_or_within ISO (PMID:14688352) MGI PMID:14688352 NCBI chrNW_004955413:4,400,326...4,422,110
Ensembl chrNW_004955413:4,408,390...4,421,535 		JBrowse link
G Chga chromogranin A involved_in ISO (PMID:15723172) UniProt PMID:15723172 NCBI chrNW_004955438:15,092,267...15,104,321
Ensembl chrNW_004955438:15,092,394...15,104,381 		JBrowse link
G Cst11 cystatin 11 involved_in ISO (PMID:12072414) UniProt PMID:12072414 NCBI chrNW_004955415:30,445,556...30,453,439 JBrowse link
G Defb118 defensin beta 118 involved_in ISO (PMID:33224970) UniProt PMID:33224970 NCBI chrNW_004955422:29,554,310...29,560,660 JBrowse link
G Defb128 defensin beta 128 involved_in ISO (PMID:15625724) UniProt PMID:15625724 NCBI chrNW_004955597:64,950...66,692
Ensembl chrNW_004955597:64,950...66,692 		JBrowse link
G Defb136 defensin beta 136 involved_in ISO (PMID:34481960) UniProt PMID:34481960 NCBI chrNW_004955403:53,168,733...53,170,177
Ensembl chrNW_004955403:53,167,242...53,170,281 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 involved_in ISO (MGI:2670828|PMID:12884308) UniProt PMID:12884308 MGI:2670828 NCBI chrNW_004955477:863,388...899,703 JBrowse link
G Drosha drosha ribonuclease III involved_in ISO (PMID:20180804) UniProt PMID:20180804 NCBI chrNW_004955426:17,387,595...17,505,126
Ensembl chrNW_004955426:17,387,534...17,502,294 		JBrowse link
G Gsdmd gasdermin D involved_in ISO (MGI:5796057|PMID:27383986) UniProt PMID:27383986 MGI:5796057 NCBI chrNW_004955454:2,265,759...2,270,569
Ensembl chrNW_004955454:2,265,753...2,271,655 		JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISO (PMID:23877675) AgBase PMID:23877675 NCBI chrNW_004955403:33,656,314...33,659,115
Ensembl chrNW_004955403:33,656,300...33,659,428 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:15114670), (PMID:20027291) BHF-UCL PMID:15114670 PMID:20027291 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620 		JBrowse link
G Il17a interleukin 17A involved_in ISO (MGI:3828868|PMID:19144317) UniProt PMID:19144317 MGI:3828868 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17f interleukin 17F involved_in ISO (MGI:3828868|PMID:19144317) UniProt PMID:19144317 MGI:3828868 NCBI chrNW_004955411:5,852,767...5,859,208
Ensembl chrNW_004955411:5,852,767...5,859,208 		JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 acts_upstream_of_or_within ISO (PMID:22801499) MGI PMID:22801499 NCBI chrNW_004955452:3,975,597...3,992,809
Ensembl chrNW_004955452:3,972,946...3,992,815 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:15114670), (PMID:20027291) BHF-UCL PMID:15114670 PMID:20027291 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:25891078) UniProt PMID:25891078 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G LOC102004444 beta-defensin 1-like involved_in ISO (PMID:25122636) UniProt PMID:25122636 NCBI chrNW_004955403:53,643,328...53,644,361
Ensembl chrNW_004955403:53,643,300...53,644,505 		JBrowse link
G LOC102013688 major histocompatibility complex class I-related gene protein involved_in
acts_upstream_of_or_within		 ISO (PMID:20581831)
(PMID:21190736)
(MGI:4818706|PMID:20581831)		 UniProt
MGI		 PMID:20581831 PMID:21190736 MGI:4818706 NCBI chrNW_004955406:20,098,544...20,117,065
Ensembl chrNW_004955406:20,098,538...20,125,057 		JBrowse link
G Lypd8 LY6/PLAUR domain containing 8 involved_in ISO (MGI:5779978|PMID:27027293) UniProt PMID:27027293 MGI:5779978 NCBI chrNW_004955418:29,811,424...29,818,756 JBrowse link
G Lyzl4 lysozyme like 4 NOT|involved_in ISO PMID:22110709 UniProt PMID:22110709 RGD:12793004 NCBI chrNW_004955420:28,333,984...28,344,180
Ensembl chrNW_004955420:28,336,162...28,344,635 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
G Mpeg1 macrophage expressed 1 involved_in ISO (PMID:23753625)
(MGI:6294207|PMID:23753625), (MGI:6294210|PMID:23257510)		 UniProt PMID:23257510 PMID:23753625 MGI:6294207 MGI:6294210 NCBI chrNW_004955511:3,783,200...3,787,300
Ensembl chrNW_004955511:3,785,019...3,787,154 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:31182790) MGI PMID:31182790 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:12791997), (PMID:12796777) UniProt PMID:12791997 PMID:12796777 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO RGD PMID:16865779 RGD:1582113 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
G Optn optineurin involved_in ISO (PMID:21617041) UniProt PMID:21617041 NCBI chrNW_004955462:1,098,118...1,150,291
Ensembl chrNW_004955462:1,107,510...1,151,269 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004955422:18,868,696...18,877,826
Ensembl chrNW_004955422:18,868,696...18,877,438 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (MGI:5787845|PMID:27184844) UniProt PMID:27184844 MGI:5787845 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Rnase6 ribonuclease A family member k6 involved_in ISO (MGI:5902674|PMID:25075772) UniProt PMID:25075772 MGI:5902674 NCBI chrNW_004955550:1,687,068...1,688,160 JBrowse link
G Rnase7 ribonuclease A family member 7 involved_in ISO (PMID:20180804) UniProt PMID:20180804 NCBI chrNW_004955550:1,796,301...1,797,801 JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO (PMID:17032919)
(MGI:3830955|PMID:17032919)		 BHF-UCL PMID:17032919 MGI:3830955 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO (PMID:6358358) MGI PMID:6358358 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608 		JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains involved_in ISO (MGI:4939978|PMID:21217009) UniProt PMID:21217009 MGI:4939978 NCBI chrNW_004955567:789,396...809,597
Ensembl chrNW_004955567:789,182...809,636 		JBrowse link
G Tfeb transcription factor EB involved_in ISO (MGI:5787845|PMID:27184844) UniProt PMID:27184844 MGI:5787845 NCBI chrNW_004955437:8,102,241...8,141,001
Ensembl chrNW_004955437:8,098,976...8,141,001 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:15661922) MGI PMID:15661922 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:22801499) MGI PMID:22801499 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within_positive_effect ISO (MGI:6391726|PMID:29887864) ARUK-UCL PMID:29887864 MGI:6391726 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO (PMID:24850429) UniProt PMID:24850429 NCBI chrNW_004955418:4,041,529...4,045,534 JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO (PMID:24042119) MGI PMID:24042119 NCBI chrNW_004955532:2,128,430...2,131,235
Ensembl chrNW_004955532:2,128,430...2,131,235 		JBrowse link
G Umod uromodulin involved_in
acts_upstream_of_or_within		 ISO (PMID:32616672)
(PMID:14665435), (PMID:14871399)		 UniProt
MGI		 PMID:14665435 PMID:14871399 PMID:32616672 NCBI chrNW_004955442:3,986,936...4,001,155
Ensembl chrNW_004955442:3,985,308...3,999,598 		JBrowse link
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dao D-amino acid oxidase involved_in ISO (PMID:25425233)
(MGI:7581102|PMID:25425233)		 UniProt PMID:25425233 MGI:7581102 NCBI chrNW_004955455:10,095,597...10,127,244
Ensembl chrNW_004955455:10,095,300...10,127,666 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO (PMID:24042119) MGI PMID:24042119 NCBI chrNW_004955532:2,128,430...2,131,235
Ensembl chrNW_004955532:2,128,430...2,131,235 		JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) UniProt PMID:21501162 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    biological process involved in interspecies interaction between organisms 1328
      response to other organism 1243
        defense response to other organism 830
          defense response to bacterium 183
            defense response to Gram-negative bacterium 47
              G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
              biosynthetic process of antibacterial peptides active against Gram-negative bacteria + 0
              neutrophil-mediated killing of gram-negative bacterium + 3
Path 2
Term Annotations click to browse term
  biological_process 12346
    response to stimulus 6681
      response to external stimulus 2006
        response to external biotic stimulus 1246
          response to other organism 1243
            response to bacterium 652
              defense response to bacterium 183
                defense response to Gram-negative bacterium 47
                  G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
                  biosynthetic process of antibacterial peptides active against Gram-negative bacteria + 0
                  neutrophil-mediated killing of gram-negative bacterium + 3
paths to the root