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ONTOLOGY REPORT - ANNOTATIONS


Term:defense response to Gram-negative bacterium
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Accession:GO:0050829 term browser browse the term
Definition:Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
Synonyms:exact_synonym: defence response to Gram-negative bacteria;   defence response to Gram-negative bacterium;   defense response to Gram-negative bacteria
 related_synonym: Gram-negative antibacterial peptide activity


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defense response to Gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07015743.1 RGD:1600115
G Adgrb1 adhesion G protein-coupled receptor B1 JBrowse link 7 115,766,484 115,828,514 RGD:1624291
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:10400853
RGD:1624291
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Bpi bactericidal/permeability-increasing protein JBrowse link 3 154,741,627 154,768,584 RGD:1624291
RGD:13792537
G Camp cathelicidin antimicrobial peptide JBrowse link 8 117,930,557 117,932,371 RGD:2316237
RGD:13792537
RGD:1624291
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:1624291
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:1600115
RGD:1624291
G Cst11 cystatin 11 JBrowse link 3 143,096,056 143,098,780 RGD:1624291
RGD:13792537
RGD:1600115
G Ctsg cathepsin G JBrowse link 15 35,107,333 35,113,678 RGD:1600115
RGD:1624291
G Defa10 defensin alpha 10 JBrowse link 16 75,498,236 75,499,012 RGD:1624291
G Defa11 defensin alpha 11 JBrowse link 16 75,517,421 75,519,605 RGD:13792537
G Defa24 defensin alpha 24 JBrowse link 16 75,345,086 75,346,122 RGD:13792537
G Defa5 defensin alpha 5 JBrowse link 16 75,338,050 75,340,401 RGD:1624291
RGD:13792537
G Defa6 defensin alpha 6 JBrowse link 16 75,400,781 75,401,655 RGD:1624291
RGD:13792537
G Defa8 defensin alpha 8 JBrowse link 16 75,428,675 75,429,568 RGD:13792537
G Defa9 defensin alpha 9 JBrowse link 16 75,465,710 75,466,604 RGD:13792537
G Defal1 defensin alpha-like 1 JBrowse link 16 75,366,925 75,367,985 RGD:13792537
G Defb1 defensin beta 1 JBrowse link 16 75,294,385 75,309,127 RGD:1624291
RGD:1600115
G Defb13 defensin beta 13 JBrowse link 16 75,027,131 75,028,977 RGD:1624291
G Defb14 defensin beta 14 JBrowse link 16 75,647,523 75,650,913 RGD:1624291
G Defb15 defensin beta 15 JBrowse link 16 75,105,290 75,107,931 RGD:1624291
G Defb20 defensin beta 20 JBrowse link 3 147,952,879 147,955,502 RGD:1624291
G Defb21 defensin beta 21 JBrowse link 3 148,047,638 148,048,952 RGD:1624291
G Defb22 defensin beta 22 JBrowse link 3 147,961,818 147,966,097 RGD:1624291
G Defb24 defensin beta 24 JBrowse link 3 148,051,364 148,057,497 RGD:1624291
G Defb4 defensin beta 4 JBrowse link 16 75,634,598 75,637,789 RGD:1624291
RGD:1600115
G Defb5 defensin beta 5 JBrowse link 16 75,597,323 75,599,483 RGD:1624291
G Dmbt1 deleted in malignant brain tumors 1 JBrowse link 1
1
201,620,642
203,149,414
201,689,905
203,228,705
RGD:1624291
RGD:1600115
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1624291
G Galp galanin-like peptide JBrowse link 1 71,352,417 71,374,457 RGD:1624291
RGD:13792537
G Gsdmd gasdermin D JBrowse link 7 116,889,147 116,894,134 RGD:1624291
G H2bc12 H2B clustered histone 12 JBrowse link 17 44,527,421 44,527,801 RGD:1624291
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Hist2h2be histone cluster 2 H2B family member E JBrowse link 2 198,360,837 198,363,399 RGD:1624291
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:1624291
RGD:1600115
G Hmgb2l1 high mobility group box 2-like 1 JBrowse link 11 49,708,038 49,709,128 RGD:1600115
G Ighe immunoglobulin heavy constant epsilon JBrowse link 6 138,066,728 138,068,606 RGD:1600115
G Ighm immunoglobulin heavy constant mu RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il22ra1 interleukin 22 receptor subunit alpha 1 JBrowse link 5 154,078,093 154,102,903 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
G Irgm immunity-related GTPase M JBrowse link 10 34,213,885 34,221,968 RGD:1624291
G Lalba lactalbumin, alpha JBrowse link 7 140,088,420 140,096,347 RGD:13792537
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:13792537
RGD:1600115
G Lce3e late cornified envelope 3E JBrowse link 2 193,275,472 193,276,006 RGD:1624291
G LOC100912990 beta-defensin 12-like JBrowse link 16 75,109,946 75,110,960 RGD:1624291
G LOC103694852 ribonuclease K6-like RGD:1624291
G Ltf lactotransferrin JBrowse link 8 119,290,416 119,313,261 RGD:1624291
G Lyc2 lysozyme C type 2 JBrowse link 7 60,316,045 60,323,610 RGD:13792537
G Lypd8 LY6/PLAUR domain containing 8 JBrowse link 10 43,817,773 43,828,812 RGD:1624291
RGD:13792537
G Lyz2 lysozyme 2 JBrowse link 7 60,335,968 60,341,264 RGD:1599862
RGD:13792537
RGD:1624291
G Lyzl1 lysozyme-like 1 JBrowse link 17 56,255,613 56,269,245 RGD:13792537
G Lyzl4 lysozyme-like 4 JBrowse link 8 130,219,984 130,228,066 RGD:12793004
G Lyzl6 lysozyme-like 6 JBrowse link 10 91,694,547 91,701,428 RGD:13792537
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:1624291
G Mpeg1 macrophage expressed 1 JBrowse link 1 228,724,559 228,729,054 RGD:1600115
RGD:1624291
G Mr1 major histocompatibility complex, class I-related JBrowse link 13 72,771,992 72,789,861 RGD:1624291
RGD:1600115
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 1 173,521,412 173,528,969 RGD:1624291
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1582113
G Np4 defensin NP-4 precursor JBrowse link 16 75,478,548 75,481,146 RGD:1624291
RGD:13792537
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:1624291
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:1600115
RGD:1624291
G Peli3 pellino E3 ubiquitin protein ligase family member 3 JBrowse link 1 220,191,209 220,204,032 RGD:1624291
G Pfpl pore forming protein-like JBrowse link 1 228,686,168 228,692,950 RGD:1600115
G Prkd1 protein kinase D1 JBrowse link 6 71,035,017 71,349,531 RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Rarres2 retinoic acid receptor responder 2 JBrowse link 4 78,205,809 78,208,956 RGD:1624291
G RatNP-3b defensin RatNP-3 precursor JBrowse link 16 75,528,348 75,530,511 RGD:13792537
G Reg3b regenerating family member 3 beta JBrowse link 4 109,467,272 109,470,510 RGD:1600115
RGD:1624291
G Reg3g regenerating family member 3 gamma JBrowse link 4 109,529,679 109,532,234 RGD:1624291
G RGD1306474 similar to RIKEN cDNA 9530003J23 JBrowse link 7 60,305,006 60,309,878 RGD:13792537
G RGD1559962 similar to High mobility group protein 2 (HMG-2) JBrowse link 1 20,416,735 20,417,959 RGD:1600115
G RGD1561694 similar to High mobility group protein 2 (HMG-2) JBrowse link 14 73,674,647 73,675,638 RGD:1600115
G Rnase2 ribonuclease A family member 2 JBrowse link 15 28,154,482 28,155,291 RGD:1624291
G Rnase3 ribonuclease A family member 3 JBrowse link 15 28,216,744 28,217,614 RGD:1624291
G Rnase6 ribonuclease A family member k6 JBrowse link 15 28,080,307 28,084,269 RGD:1624291
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:1624291
G Rpl30 ribosomal protein L30 JBrowse link 7 73,213,538 73,216,431 RGD:1624291
G Rps19 ribosomal protein S19 JBrowse link 1 81,750,873 81,756,629 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1624291
RGD:1600115
G Spaca3 sperm acrosome associated 3 JBrowse link 10 68,227,736 68,235,295 RGD:13792537
G Spaca5 sperm acrosome associated 5 JBrowse link X 912,770 915,953 RGD:13792537
G Ssc5d scavenger receptor cysteine rich family member with 5 domains JBrowse link 1 72,443,750 72,462,293 RGD:1624291
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:1624291
G Tfeb transcription factor EB JBrowse link 9 15,208,141 15,264,101 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:13792537
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:1624291
RGD:13792537
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link 8 116,318,963 116,322,181 RGD:1624291
G Umod uromodulin JBrowse link 1 189,186,027 189,199,939 RGD:1624291
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:1624291
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1600115
RGD:1624291
G Trem1 triggering receptor expressed on myeloid cells 1 JBrowse link 9 14,727,887 14,743,371 RGD:1624291
G Trem3 triggering receptor expressed on myeloid cells 3 JBrowse link 9 14,713,935 14,725,945 RGD:1600115
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link 8 116,318,963 116,322,181 RGD:1624291
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    interspecies interaction between organisms 1773
      response to other organism 1575
        defense response to other organism 993
          defense response to bacterium 377
            defense response to Gram-negative bacterium 102
              G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
              biosynthetic process of antibacterial peptides active against Gram-negative bacteria + 1
              neutrophil-mediated killing of gram-negative bacterium + 7
              positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    response to stimulus 10457
      response to external stimulus 3083
        response to external biotic stimulus 1579
          response to other organism 1575
            response to bacterium 987
              defense response to bacterium 377
                defense response to Gram-negative bacterium 102
                  G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
                  biosynthetic process of antibacterial peptides active against Gram-negative bacteria + 1
                  neutrophil-mediated killing of gram-negative bacterium + 7
                  positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.