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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of coagulation
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Accession:GO:0050819 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
Synonyms:exact_synonym: down regulation of coagulation;   downregulation of coagulation;   negative regulation of clotting
 narrow_synonym: inhibition of coagulation
 related_synonym: anticoagulant activity


show annotations for term's descendants           Sort by:
negative regulation of coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 involved_in ISO (PMID:12138164) RGD PMID:12138164 NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in TAS
IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:25651845)		 Ensembl
UniProt
RGD		 PMID:25651845 PMID:14995995 GO_REF:0000024 GO_REF:0000107, RGD:1578389 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Procr protein C receptor involved_in ISO
IBA
IEA		 (PMID:19696402)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:19696402 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903 		JBrowse link
G Pros1 protein S IDA RGD PMID:7608128 RGD:2300015 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286 		JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3028929 (PMID:14702107)		 Ensembl
RGD		 PMID:14702107 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11848438 GO_REF:0000033, RGD:632532 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA		 (PMID:12855810)
GO_REF:0000107		 RGD
Ensembl		 PMID:12855810 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
IEA		 (PMID:16846481)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:16846481 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fgl1 fibrinogen-like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000043
MGI:3789962 (PMID:15869579)		 UniProt
RGD		 PMID:15869579 GO_REF:0000043 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrg l1 histidine-rich glycoprotein like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
(PMID:9733098)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:9733098 GO_REF:0000033 GO_REF:0000118 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plg plasminogen involved_in ISO
IEA		 (PMID:14688145), (PMID:17307854), (PMID:22025510)
GO_REF:0000104		 RGD
UniProt		 PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286 		JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:4052628) RGD PMID:4052628 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Kng1 kininogen 1 involved_in ISO
IBA		 (PMID:11970955)
GO_REF:0000033		 RGD
GO_Central		 PMID:11970955 GO_REF:0000033 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Kng1_v1 kininogen 1, variant 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118
G Kng2 kininogen 2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IEA		 MGI:2183063 (PMID:9616155), (PMID:9788960)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:9616155 PMID:9788960 PMID:1440533 GO_REF:0000033 GO_REF:0000118, RGD:11100042 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IDA
ISO		 PMID:17379830
(PMID:17379830)		 RGD PMID:17379830 PMID:17379830 RGD:8553298 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356 		JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:3789962 (PMID:15869579)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:15869579 GO_REF:0000033 GO_REF:0000118 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrg l1 histidine-rich glycoprotein like 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA		 (PMID:2503541)
GO_REF:0000107		 RGD
Ensembl		 PMID:2503541 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO		 (PMID:134998) RGD PMID:134998 PMID:6506034 RGD:1625541 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:8995232)		 Ensembl
RGD		 PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (PMID:10557321), (PMID:11435305) RGD PMID:10557321 PMID:11435305 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IEA
ISS		 (PMID:2538439)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:2538439)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:8188664)		 UniProt
Ensembl
RGD		 PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (PMID:19855083) RGD PMID:19855083 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (PMID:19218546) RGD PMID:19218546 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(MGI:1202206|PMID:9501222)		 UniProt
RGD		 PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16195328)		 Ensembl
RGD		 PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18541721)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18541721 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3835235|PMID:19008452)		 UniProt
RGD		 PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3813784|PMID:16940418)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16940418 GO_REF:0000024 GO_REF:0000107 MGI:3813784 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4418017|PMID:19855083)		 Ensembl
RGD		 PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO UniProtKB:P35951 (MGI:5905608|PMID:27430239) RGD PMID:27430239 MGI:5905608 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:30425049)
(MGI:6284734|PMID:30425049)		 RGD PMID:30425049 MGI:6284734 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:20585042) RGD PMID:20585042 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO		 GO_REF:0000107
(PMID:89876)		 Ensembl
RGD		 PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    multicellular organismal process 8921
      coagulation 206
        negative regulation of coagulation 50
          negative regulation of blood coagulation + 46
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of multicellular organismal process 3373
          regulation of coagulation 72
            negative regulation of coagulation 50
              negative regulation of blood coagulation + 46
paths to the root