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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of coagulation
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Accession:GO:0050819 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
Synonyms:exact_synonym: down regulation of coagulation;   downregulation of coagulation;   negative regulation of clotting
 narrow_synonym: inhibition of coagulation
 related_synonym: anticoagulant activity

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negative regulation of coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130 		JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 involved_in ISO (PMID:12138164) RGD PMID:12138164 NCBI chr20:40,236,437...40,545,502
Ensembl chr20:40,236,437...40,545,494 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in TAS
ISO
ISS		 (PMID:25651845)
GO_REF:0000024		 RGD
UniProt		 PMID:25651845, PMID:14995995 GO_REF:0000024, RGD:1578389 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G Procr protein C receptor involved_in ISO
IBA		 (PMID:19696402)
PMID:21873635		 RGD PMID:19696402, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595 		JBrowse link
G Pros1 protein S IDA RGD PMID:7608128 RGD:2300015 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134 		JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO MGI:3028929 (MGI:3027337|PMID:14702107) RGD PMID:14702107 MGI:3027337 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11848438, PMID:21873635, PMID:21873635 RGD:632532, RGD:13792537, RGD:13792537 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760 		JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G F2 coagulation factor II involved_in IEA
ISO		 GO_REF:0000107
(PMID:12855810)		 Ensembl
RGD		 PMID:12855810 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IEA
IBA		 (PMID:16846481)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:16846481, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952 		JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458 		JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plau plasminogen activator, urokinase involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(MGI:1277054|PMID:9733098)		 Ensembl
RGD		 PMID:9733098, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:1277054, RGD:13792537, RGD:13792537 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Plg plasminogen involved_in IEA
ISO		 GO_REF:0000104
(PMID:14688145), (PMID:17307854), (PMID:22025510)		 UniProt
RGD		 PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776 		JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134 		JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078 		JBrowse link
negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:21868574)		 Ensembl
RGD		 PMID:21868574 GO_REF:0000107 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307 		JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Apoh apolipoprotein H involved_in ISO
IEA		 (PMID:4052628)
GO_REF:0000107		 RGD
Ensembl		 PMID:4052628 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938 		JBrowse link
G Cd34 CD34 molecule involved_in ISO
ISS		 (PMID:17505307)
GO_REF:0000024		 RGD
UniProt		 PMID:17505307 GO_REF:0000024 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Kng1 kininogen 1 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000107		 Ensembl PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr11:81,421,672...81,444,466
Ensembl chr11:81,421,676...81,444,621 		JBrowse link
G Kng2 kininogen 2 involved_in ISO
IBA		 (PMID:11970955)
PMID:21873635		 RGD PMID:11970955, PMID:21873635 RGD:13792537 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in IDA
IBA
ISO		 PMID:21873635
MGI:2183063 (MGI:1261704|PMID:9616155), (MGI:1306904|PMID:9788960)		 RGD PMID:9616155 PMID:9788960, PMID:1440533, PMID:21873635, PMID:21873635 MGI:1261704 MGI:1306904, RGD:11100042, RGD:13792537, RGD:13792537 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IDA		 (PMID:17379830) RGD PMID:17379830, PMID:17379830, PMID:17379830 RGD:8553298, RGD:8553298 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094 		JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618 		JBrowse link
G Thbd thrombomodulin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325 		JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:58,814,805...58,847,564
Ensembl chr 7:58,814,805...58,847,563 		JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA		 (PMID:14726399)
GO_REF:0000107		 RGD
Ensembl		 PMID:14726399 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938 		JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
IBA		 MGI:3789962 (MGI:3789419|PMID:15869579)
PMID:21873635		 RGD PMID:15869579, PMID:21873635, PMID:21873635 MGI:3789419, RGD:13792537, RGD:13792537 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952 		JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA		 (PMID:2503541)
GO_REF:0000107		 RGD
Ensembl		 PMID:2503541 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO		 (PMID:134998) RGD PMID:134998, PMID:6506034 RGD:1625541 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA		 (PMID:8995232)
GO_REF:0000107		 RGD
Ensembl		 PMID:8995232 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162 		JBrowse link
G Gp5 glycoprotein V (platelet) ISO MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) RGD PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr11:73,015,380...73,017,570 JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
ISS
IEA		 (PMID:2538439)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:2538439)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA
ISS		 (PMID:8188664)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031 		JBrowse link
G Serpine2 serpin family E member 2 ISO MGI:2387774 (MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499 		JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 involved_in ISO (PMID:19218546)
(MGI:3848389|PMID:19218546)		 RGD PMID:19218546 MGI:3848389 NCBI chr19:46,005,055...46,167,912
Ensembl chr19:46,005,277...46,101,250 		JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(MGI:1202206|PMID:9501222)		 UniProt
RGD		 PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16195328)		 Ensembl
RGD		 PMID:16195328 GO_REF:0000107 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162 		JBrowse link
G Cd9 CD9 molecule involved_in ISO
ISS		 (PMID:18541721)
GO_REF:0000024		 RGD
UniProt		 PMID:18541721 GO_REF:0000024 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3835235|PMID:19008452)		 UniProt
RGD		 PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345 		JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514 		JBrowse link
G Prkcd protein kinase C, delta involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:3813784|PMID:16940418)		 Ensembl
UniProt
RGD		 PMID:16940418 GO_REF:0000024 GO_REF:0000107 MGI:3813784 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4418017|PMID:19855083)		 Ensembl
RGD		 PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 IEA
ISO		 GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)		 Ensembl
RGD		 PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B ISO (MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:4838721 NCBI chr 8:45,224,053...45,375,450
Ensembl chr 8:45,223,992...45,375,435 		JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698 		JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:89876)
GO_REF:0000107		 RGD
Ensembl		 PMID:89876 GO_REF:0000107 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776 		JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    multicellular organismal process 9072
      coagulation 193
        negative regulation of coagulation 50
          negative regulation of blood coagulation + 48
Path 2
Term Annotations click to browse term
  biological_process 20078
    biological regulation 13898
      regulation of biological process 13140
        regulation of multicellular organismal process 2925
          regulation of coagulation 70
            negative regulation of coagulation 50
              negative regulation of blood coagulation + 48
paths to the root