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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of synaptic transmission
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Accession:GO:0050805 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
Synonyms:exact_synonym: down regulation of synaptic transmission;   downregulation of synaptic transmission
 narrow_synonym: inhibition of synaptic transmission


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negative regulation of synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
(PMID:17327472)
GO_REF:0000024
RGD
UniProt
PMID:17327472 GO_REF:0000024 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adnp activity-dependent neuroprotector homeobox IMP RGD PMID:15963648 RGD:2312778 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702
JBrowse link
G Bche butyrylcholinesterase IDA RGD PMID:16275899 RGD:1599456 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:17314300 RGD:1625010 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:17314300 RGD:1625010 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd4 dopamine receptor D4 IDA RGD PMID:17314300 RGD:1625010 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IDA RGD PMID:12604336 RGD:2315497 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gnai1 G protein subunit alpha i1 IMP RGD PMID:11923410 RGD:625670 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:11923410 RGD:625670 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Grm4 glutamate metabotropic receptor 4 TAS PMID:16178733 UniProt PMID:16178733 RGD:8554134 NCBI chr20:6,745,682...6,791,521
Ensembl chr20:6,745,682...6,791,519
JBrowse link
G Il1b interleukin 1 beta IEA
ISO
GO_REF:0000107
(MGI:MGI:5902681|PMID:20739563)
Ensembl
RGD
PMID:20739563 GO_REF:0000107, MGI:MGI:5902681 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:15295007 RGD:1642503 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Pcdh17 protocadherin 17 ISO (MGI:MGI:5514320|PMID:23684785) RGD PMID:23684785 MGI:MGI:5514320 NCBI chr15:67,555,835...67,647,990
Ensembl chr15:67,555,835...67,645,088
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 IDA RGD PMID:19734897 RGD:2314692 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Tnr tenascin R ISO
IEA
MGI:MGI:2154583 (MGI:MGI:3039956|PMID:15033179)
GO_REF:0000107
RGD
Ensembl
PMID:15033179 GO_REF:0000107, MGI:MGI:3039956 NCBI chr13:77,602,249...77,678,385
Ensembl chr13:77,485,113...77,678,437
JBrowse link
long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase ISO (MGI:MGI:4829719|PMID:20657592) RGD PMID:20657592 MGI:MGI:4829719 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Arf1 ADP-ribosylation factor 1 IDA PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:10097163 RGD:2307271 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Drd1 dopamine receptor D1 ISO
IEA
MGI:MGI:1857158 (MGI:MGI:3036431|PMID:14981263)
GO_REF:0000107
RGD
Ensembl
PMID:14981263 GO_REF:0000107, MGI:MGI:3036431 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd5 dopamine receptor D5 ISO
IEA
(MGI:MGI:3586401|PMID:13679419)
GO_REF:0000107
RGD
Ensembl
PMID:13679419 GO_REF:0000107, MGI:MGI:3586401 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO
IEA
MGI:MGI:99401 (MGI:MGI:5529732|PMID:24259587)
GO_REF:0000107
RGD
Ensembl
PMID:24259587 GO_REF:0000107, MGI:MGI:5529732 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Grid2ip Grid2 interacting protein ISO MGI:MGI:3796575 (MGI:MGI:3796257|PMID:18509461) RGD PMID:18509461 MGI:MGI:3796257 NCBI chr12:13,221,334...13,257,365
Ensembl chr12:13,221,513...13,251,112
JBrowse link
G Mgll monoglyceride lipase ISO (MGI:MGI:4829719|PMID:20657592) RGD PMID:20657592 MGI:MGI:4829719 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Pick1 protein interacting with PRKCA 1 IDA PMID:21252856 UniProt PMID:21252856 RGD:8554238 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840
JBrowse link
G Plk2 polo-like kinase 2 IDA PMID:21382555 UniProt PMID:21382555 RGD:7241548 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Pten phosphatase and tensin homolog IMP NMDA receptor-dependent RGD PMID:20628354 RGD:4144068 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:20826662 RGD:10041066 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 ISO
ISS
(MGI:MGI:5432970|PMID:22699620)
GO_REF:0000024
RGD
BHF-UCL
PMID:22699620 GO_REF:0000024, MGI:MGI:5432970 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 ISO
IEA
(MGI:MGI:5320264|PMID:21795692)
GO_REF:0000107
RGD
Ensembl
PMID:21795692 GO_REF:0000107, MGI:MGI:5320264 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Slc24a1 solute carrier family 24 member 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:70,409,683...70,438,352
Ensembl chr 8:70,408,528...70,436,028
JBrowse link
G Slc24a2 solute carrier family 24 member 2 ISO
IBA
MGI:MGI:3663782 (MGI:MGI:3640012|PMID:16407245)
PMID:21873635
RGD PMID:16407245, PMID:21873635 MGI:MGI:3640012, RGD:13792537 NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 ISO (MGI:MGI:6305031|PMID:27457814) RGD PMID:27457814 MGI:MGI:6305031 NCBI chr14:79,538,911...79,912,333
Ensembl chr14:79,538,911...79,912,333
JBrowse link
G Srf serum response factor ISO MGI:MGI:2385465|MGI:MGI:2678305 (MGI:MGI:3652465|PMID:16600861) RGD PMID:16600861 MGI:MGI:3652465 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO MGI:MGI:2183278 (MGI:MGI:3695670|PMID:17110441) RGD PMID:17110441 MGI:MGI:3695670 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln1 cerebellin 1 precursor ISO (PMID:27418511) RGD PMID:27418511 NCBI chr19:20,607,507...20,611,316
Ensembl chr19:20,607,507...20,611,316
JBrowse link
G Celf4 CUGBP, Elav-like family member 4 ISO MGI:MGI:5425630 (MGI:MGI:5313512|PMID:21745337) RGD PMID:21745337 MGI:MGI:5313512 NCBI chr18:17,689,090...18,079,835
Ensembl chr18:17,698,038...17,716,880
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IMP RGD PMID:17632064 RGD:10044262 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (MGI:MGI:4941068|PMID:21307259) RGD PMID:21307259 MGI:MGI:4941068 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Mtmr2 myotubularin related protein 2 IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Nlgn3 neuroligin 3 ISO
IEA
(MGI:MGI:5286761|PMID:21808020)
GO_REF:0000107
RGD
Ensembl
PMID:21808020 GO_REF:0000107, MGI:MGI:5286761 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:12055128 RGD:1642608 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Pten phosphatase and tensin homolog ISO (MGI:MGI:5320272|PMID:21411674) RGD PMID:21411674 MGI:MGI:5320272 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 ISO MGI:MGI:2180817 (MGI:MGI:2157237|PMID:11553273) RGD PMID:11553273 MGI:MGI:2157237 NCBI chr 8:21,984,914...21,995,806
Ensembl chr 8:21,984,914...21,995,806
JBrowse link
G Tmem25 transmembrane protein 25 ISO
IBA
(MGI:MGI:6370252|PMID:31424425)
PMID:21873635
RGD PMID:31424425, PMID:21873635 MGI:MGI:6370252, RGD:13792537 NCBI chr 8:49,100,759...49,106,258
Ensembl chr 8:49,100,759...49,106,177
JBrowse link
negative regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO MGI:MGI:95808 (MGI:MGI:5529732|PMID:24259587) RGD PMID:24259587 MGI:MGI:5529732 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEA
ISO
GO_REF:0000107
ComplexPortal:CPX-1134 (PMID:20739563)
Ensembl
RGD
PMID:20739563 GO_REF:0000107 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Fmr1 FMRP translational regulator 1 ISO
ISS
(MGI:MGI:2136541|PMID:11438589)
GO_REF:0000024
RGD
UniProt
PMID:11438589 GO_REF:0000024, MGI:MGI:2136541 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syne1 spectrin repeat containing nuclear envelope protein 1 IMP RGD PMID:24191017 RGD:13209020 NCBI chr 1:41,608,287...41,763,591
NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
JBrowse link
negative regulation of neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 ISO MGI:MGI:2179834 (MGI:MGI:3841883|PMID:18094106) RGD PMID:18094106 MGI:MGI:3841883 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Nf1 neurofibromin 1 ISO
IEA
MGI:MGI:1857478|MGI:MGI:97321 (MGI:MGI:3612345|PMID:16298082)
GO_REF:0000107
RGD
Ensembl
PMID:16298082 GO_REF:0000107, MGI:MGI:3612345 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO MGI:MGI:2152971|MGI:MGI:2152972 (MGI:MGI:5634213|PMID:25730884)
(PMID:25730884)
RGD PMID:25730884 MGI:MGI:5634213 NCBI chr 9:81,566,074...81,634,531
Ensembl chr 9:81,566,074...81,634,534
JBrowse link
G Slc30a1 solute carrier family 30 member 1 IMP PMID:16741752 BHF-UCL PMID:16741752 RGD:8554228 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Syt4 synaptotagmin 4 IDA PMID:10397765 ParkinsonsUK-UCL PMID:10397765 RGD:11535116 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,880,015...50,069,998 JBrowse link
negative regulation of synaptic transmission, dopaminergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:16775195, PMID:21873635 RGD:1600308, RGD:13792537 NCBI chr 5:139,625,783...139,677,300
Ensembl chr 5:139,627,576...139,677,300
JBrowse link
G Pmch pro-melanin-concentrating hormone IDA RGD PMID:15555641 RGD:1642493 NCBI chr 7:28,655,206...28,656,522
Ensembl chr 7:28,654,733...28,657,522
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18764909 RGD:2300272 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:20730799 RGD:4889470 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
negative regulation of synaptic transmission, GABAergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor NOT IMP
IDA
in immature hippocampal CA1 neurons
in postnatal 30 day hippocampal CA1 neurons
RGD PMID:12626609, PMID:12626609 RGD:1625273, RGD:1625273 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO (MGI:MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:MGI:3694324 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:19616018 RGD:2316192 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA RGD PMID:12533604 RGD:1642497 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17229091 RGD:1626455 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:11796508 RGD:1625505 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Slc6a1 solute carrier family 6 member 1 IMP RGD PMID:17317750 RGD:1643193 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (MGI:MGI:3691953|PMID:17167098) RGD PMID:17167098 MGI:MGI:3691953 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO
ISS
(MGI:MGI:5050342|PMID:21496646)
GO_REF:0000024
RGD
UniProt
PMID:21496646 GO_REF:0000024, MGI:MGI:5050342 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002
JBrowse link
G Drd2 dopamine receptor D2 ISO
IBA
MGI:MGI:1857875|MGI:MGI:2387895|MGI:MGI:2675755 (MGI:MGI:3610921|PMID:11160501), (MGI:MGI:3628700|PMID:15489038)
PMID:21873635
RGD PMID:11160501, PMID:15489038, PMID:21873635 MGI:MGI:3610921, MGI:MGI:3628700, RGD:13792537 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA
ISO
MGI:MGI:95815 (MGI:MGI:3575241|PMID:11985817) RGD PMID:11985817, PMID:17395219 MGI:MGI:3575241, RGD:1642466 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 IDA
ISO
PMID:16420445
MGI:MGI:95814 (MGI:MGI:3575241|PMID:11985817)
RGD PMID:11985817, PMID:16420445 MGI:MGI:3575241, RGD:8554693 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 IDA PMID:16420445 UniProt PMID:16420445 RGD:8554693 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17392733 RGD:1626454 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17016851 RGD:1624386 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:16190896 RGD:1642508 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:15132431 RGD:6482754 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,880,015...50,069,998 JBrowse link
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO (MGI:MGI:5490391|PMID:23616533) RGD PMID:23616533 MGI:MGI:5490391 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO
IBA
MGI:MGI:894315 (MGI:MGI:5490391|PMID:23616533)
PMID:21873635
RGD PMID:23616533, PMID:21873635 MGI:MGI:5490391, RGD:13792537 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family ISO
IBA
MGI:MGI:97852 (MGI:MGI:5490391|PMID:23616533)
PMID:21873635
RGD PMID:23616533, PMID:21873635 MGI:MGI:5490391, RGD:13792537 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Syt4 synaptotagmin 4 ISO (MGI:MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:MGI:4457852 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
positive regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:1860567|PMID:10864938)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10864938 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1860567 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Cbln1 cerebellin 1 precursor ISO (PMID:27418511) RGD PMID:27418511 NCBI chr19:20,607,507...20,611,316
Ensembl chr19:20,607,507...20,611,316
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP RGD PMID:28894415 RGD:38501107 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 IEA
ISO
GO_REF:0000107
(PMID:27418511)
Ensembl
RGD
PMID:27418511 GO_REF:0000107 NCBI chr 4:94,068,112...95,476,864
Ensembl chr 4:94,696,965...95,442,778
JBrowse link
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 IMP RGD PMID:27009485 RGD:11049506 NCBI chr  X:22,212,137...22,293,810
Ensembl chr  X:22,212,132...22,294,402
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5634878|PMID:24494598)
Ensembl
UniProt
RGD
PMID:24494598 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5634878 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Mapt microtubule-associated protein tau IMP RGD PMID:24298146 RGD:10412705 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Pirb paired Ig-like receptor B ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:MGI:5511064|PMID:24052308) RGD PMID:24052308 MGI:MGI:5511064 NCBI chr 1:64,074,097...64,081,568
Ensembl chr 1:64,074,231...64,081,438
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Stau2 staufen double-stranded RNA binding protein 2 IMP RGD PMID:21508097 RGD:10043164 NCBI chr 5:2,257,910...2,497,429 JBrowse link
regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein ISS
ISO
GO_REF:0000024
(MGI:MGI:6148485|PMID:29264923)
UniProt
RGD
PMID:29264923 GO_REF:0000024, MGI:MGI:6148485 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Bcl2l1 Bcl2-like 1 IMP PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Dgki diacylglycerol kinase, iota ISO MGI:MGI:3584141 (MGI:MGI:4936793|PMID:21119615) RGD PMID:21119615 MGI:MGI:4936793 NCBI chr 4:64,365,115...64,831,473
Ensembl chr 4:64,374,342...64,831,473
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 ISO
IEA
ISS
(MGI:MGI:5320264|PMID:21795692)
GO_REF:0000107
RGD
Ensembl
PMID:21795692, PMID:21795692 GO_REF:0000107, MGI:MGI:5320264, RGD:7349315 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Sorcs3 sortilin-related VPS10 domain containing receptor 3 ISO MGI:MGI:5562419 (MGI:MGI:5559089|PMID:24069373) RGD PMID:24069373 MGI:MGI:5559089 NCBI chr 1:267,986,305...268,620,331
Ensembl chr 1:268,189,277...268,620,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of signaling 1373
        negative regulation of synaptic transmission 83
          long-term synaptic depression + 35
          negative regulation by symbiont of host synaptic transmission + 0
          negative regulation of excitatory postsynaptic potential + 12
          negative regulation of neuromuscular synaptic transmission 0
          negative regulation of neurotransmitter secretion + 12
          negative regulation of synaptic transmission, GABAergic 8
          negative regulation of synaptic transmission, cholinergic + 1
          negative regulation of synaptic transmission, dopaminergic 4
          negative regulation of synaptic transmission, glutamatergic + 12
          negative regulation of synaptic transmission, glycinergic + 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell communication 7664
        cell-cell signaling 1738
          synaptic signaling 917
            trans-synaptic signaling 889
              anterograde trans-synaptic signaling 880
                chemical synaptic transmission 880
                  modulation of chemical synaptic transmission 656
                    negative regulation of synaptic transmission 83
                      long-term synaptic depression + 35
                      negative regulation by symbiont of host synaptic transmission + 0
                      negative regulation of excitatory postsynaptic potential + 12
                      negative regulation of neuromuscular synaptic transmission 0
                      negative regulation of neurotransmitter secretion + 12
                      negative regulation of synaptic transmission, GABAergic 8
                      negative regulation of synaptic transmission, cholinergic + 1
                      negative regulation of synaptic transmission, dopaminergic 4
                      negative regulation of synaptic transmission, glutamatergic + 12
                      negative regulation of synaptic transmission, glycinergic + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.