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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of synaptic transmission
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Accession:GO:0050805 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
Synonyms:exact_synonym: down regulation of synaptic transmission;   downregulation of synaptic transmission
 narrow_synonym: inhibition of synaptic transmission


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negative regulation of synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IDA (PMID:17327472) UniProtKB PMID:17327472 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADNP activity dependent neuroprotector homeobox IEA Ensembl GO_REF:0000107 NCBI chr20:50,888,918...50,931,437
Ensembl chr20:50,888,916...50,931,437
JBrowse link
G BCHE butyrylcholinesterase IEA Ensembl GO_REF:0000107 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:17314300 RGD:1625010 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:17314300 RGD:1625010 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:12604336 RGD:2315497 NCBI chr 6:29,602,230...29,633,183
Ensembl chr 6:29,555,629...29,633,976
JBrowse link
G GNAI1 G protein subunit alpha i1 IEA Ensembl GO_REF:0000107 NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181
JBrowse link
G GNAI2 G protein subunit alpha i2 IEA Ensembl GO_REF:0000107 NCBI chr 3:50,227,068...50,259,362
Ensembl chr 3:50,226,292...50,259,362
JBrowse link
G IL1B interleukin 1 beta ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:15295007 RGD:1642503 NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078
JBrowse link
G PCDH17 protocadherin 17 IEA Ensembl GO_REF:0000107 NCBI chr13:57,630,104...57,729,311
Ensembl chr13:57,631,744...57,729,311
JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 ISO RGD PMID:19734897 RGD:2314692 NCBI chr 2:172,735,282...173,052,893
Ensembl chr 2:172,735,274...173,052,893
JBrowse link
G TNR tenascin R IEA Ensembl GO_REF:0000107 NCBI chr 1:175,315,194...175,743,702
Ensembl chr 1:175,315,194...175,743,616
JBrowse link
long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD6 abhydrolase domain containing 6, acylglycerol lipase IEA Ensembl GO_REF:0000107 NCBI chr 3:58,237,532...58,294,736
Ensembl chr 3:58,237,532...58,295,693
JBrowse link
G ARF1 ADP ribosylation factor 1 ISS UniProtKB GO_REF:0000024 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,660...228,099,212
JBrowse link
G CD38 CD38 molecule IEA Ensembl GO_REF:0000107 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G DRD1 dopamine receptor D1 IEA Ensembl GO_REF:0000107 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD5 dopamine receptor D5 IEA Ensembl GO_REF:0000107 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:153,490,670...153,813,873
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRID2IP Grid2 interacting protein IEA Ensembl GO_REF:0000107 NCBI chr 7:6,496,778...6,551,436
Ensembl chr 7:6,497,462...6,551,436
JBrowse link
G MGLL monoglyceride lipase ISO (MGI:MGI:4829719|PMID:20657592) MGI PMID:20657592 MGI:MGI:4829719 NCBI chr 3:127,689,066...127,823,228
Ensembl chr 3:127,689,062...128,052,190
JBrowse link
G PICK1 protein interacting with PRKCA 1 ISS UniProtKB GO_REF:0000024 NCBI chr22:38,056,311...38,075,704
Ensembl chr22:38,056,311...38,075,701
JBrowse link
G PLK2 polo like kinase 2 ISS UniProtKB GO_REF:0000024 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139
JBrowse link
G PTEN phosphatase and tensin homolog IEA Ensembl GO_REF:0000107 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G PTK2B protein tyrosine kinase 2 beta IEA Ensembl GO_REF:0000107 NCBI chr 8:27,311,478...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 IEA
ISS
(PMID:22699620) Ensembl
BHF-UCL
PMID:22699620 GO_REF:0000107 NCBI chr11:70,467,854...71,252,724
Ensembl chr11:70,467,856...71,252,577
JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 IEA Ensembl GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,298
JBrowse link
G SLC24A1 solute carrier family 24 member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:65,611,313...65,661,002
Ensembl chr15:65,611,366...65,660,995
JBrowse link
G SLC24A2 solute carrier family 24 member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:19,507,452...20,307,888
Ensembl chr 9:19,507,452...19,786,928
JBrowse link
G SORCS2 sortilin related VPS10 domain containing receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:7,192,538...7,742,828
Ensembl chr 4:7,192,538...7,742,836
JBrowse link
G SRF serum response factor IEA Ensembl GO_REF:0000107 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506
JBrowse link
G STXBP1 syntaxin binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966
JBrowse link
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLN1 cerebellin 1 precursor IMP (PMID:27418511) UniProtKB PMID:27418511 NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838
JBrowse link
G CELF4 CUGBP Elav-like family member 4 IEA Ensembl GO_REF:0000107 NCBI chr18:37,243,040...37,565,798
Ensembl chr18:37,243,040...37,565,827
JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 IEA Ensembl GO_REF:0000107 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151
JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISS ParkinsonsUK-UCL GO_REF:0000024 NCBI chr12:40,224,890...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G MTMR2 myotubularin related protein 2 ISS BHF-UCL GO_REF:0000024 NCBI chr11:95,832,880...95,924,110
Ensembl chr11:95,821,766...95,925,315
Ensembl chr11:95,821,766...95,925,315
Ensembl chr11:95,821,766...95,925,315
JBrowse link
G NLGN3 neuroligin 3 IEA Ensembl GO_REF:0000107 NCBI chr  X:71,144,389...71,175,307
Ensembl chr  X:71,144,831...71,171,201
JBrowse link
G NLGN4X neuroligin 4 X-linked IDA (PMID:19726642) BHF-UCL PMID:19726642 NCBI chr  X:5,890,042...6,228,878
Ensembl chr  X:5,840,637...6,228,867
JBrowse link
G NPY2R neuropeptide Y receptor Y2 IEA Ensembl GO_REF:0000107 NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19033459 RGD:10413844 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
G PTEN phosphatase and tensin homolog ISS BHF-UCL GO_REF:0000024 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G S1PR2 sphingosine-1-phosphate receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr19:10,221,433...10,231,331
Ensembl chr19:10,221,433...10,231,331
JBrowse link
G TMEM25 transmembrane protein 25 IEA
IBA
ISS
(PMID:21873635) Ensembl
GO_Central
UniProt
PMID:21873635 GO_REF:0000024, GO_REF:0000107 NCBI chr11:118,531,189...118,547,286
Ensembl chr11:118,531,041...118,547,280
JBrowse link
negative regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G AGER advanced glycosylation end-product specific receptor IGI (PMID:20739563) ARUK-UCL PMID:20739563 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G FMR1 FMRP translational regulator 1 ISS UniProtKB GO_REF:0000024 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,951...147,951,125
Ensembl chr  X:147,911,951...147,951,125
JBrowse link
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYNE1 spectrin repeat containing nuclear envelope protein 1 ISO RGD PMID:24191017 RGD:13209020 NCBI chr 6:152,121,684...152,637,395
Ensembl chr 6:152,121,684...152,637,801
JBrowse link
negative regulation of neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASIC1 acid sensing ion channel subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611
JBrowse link
G NF1 neurofibromin 1 IEA Ensembl GO_REF:0000107 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing IMP (PMID:25730884) SynGO-UCL PMID:25730884 NCBI chr 2:218,270,485...218,346,793
Ensembl chr 2:218,270,392...218,346,793
JBrowse link
G SLC30A1 solute carrier family 30 member 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SYT11 synaptotagmin 11 TAS (PMID:21563316) ParkinsonsUK-UCL PMID:21563316 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
G SYT4 synaptotagmin 4 ISO PMID:10397765 ParkinsonsUK-UCL PMID:10397765 RGD:11535116 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R9A protein phosphatase 1 regulatory subunit 9A IEA Ensembl GO_REF:0000107 NCBI chr 7:94,907,202...95,296,415
Ensembl chr 7:94,907,202...95,296,415
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IMP (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
negative regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) IC (PMID:1517212) HGNC PMID:1517212 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
negative regulation of synaptic transmission, dopaminergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNQ4 potassium voltage-gated channel subfamily Q member 4 ISO RGD PMID:16775195 RGD:1600308 NCBI chr 1:40,783,787...40,840,457
Ensembl chr 1:40,783,787...40,840,452
JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:15555641 RGD:1642493 NCBI chr12:102,196,459...102,199,540
Ensembl chr12:102,196,459...102,197,833
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G SLC6A4 solute carrier family 6 member 4 IEA Ensembl GO_REF:0000107 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
JBrowse link
negative regulation of synaptic transmission, GABAergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor NOT IEA
ISO
in postnatal 30 day hippocampal CA1 neurons Ensembl
RGD
PMID:12626609 GO_REF:0000107, RGD:1625273 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G BDNF brain derived neurotrophic factor IEA Ensembl GO_REF:0000107 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G CNR2 cannabinoid receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO RGD PMID:12533604 RGD:1642497 NCBI chr21:29,536,933...29,939,996
Ensembl chr21:29,536,933...29,940,033
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B IEA Ensembl GO_REF:0000107 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,461,753...77,463,773
Ensembl chr 6:77,461,753...77,463,773
JBrowse link
G NPY5R neuropeptide Y receptor Y5 IEA Ensembl GO_REF:0000107 NCBI chr 4:163,336,968...163,352,277
Ensembl chr 4:163,343,892...163,351,934
JBrowse link
G SLC6A1 solute carrier family 6 member 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:10,992,748...11,039,247
Ensembl chr 3:10,992,186...11,039,247
JBrowse link
G STXBP1 syntaxin binding protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ATAD1 ATPase family AAA domain containing 1 ISS UniProtKB GO_REF:0000024 NCBI chr10:87,751,512...87,841,359
Ensembl chr10:87,751,512...87,841,343
JBrowse link
G DRD2 dopamine receptor D2 ISS
IBA
(PMID:21873635) BHF-UCL
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO (MGI:MGI:3575241|PMID:11985817) RGD
MGI
PMID:11985817, PMID:17395219 MGI:MGI:3575241, RGD:1642466 NCBI chr21:29,536,933...29,939,996
Ensembl chr21:29,536,933...29,940,033
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:101,181,257...102,070,083
JBrowse link
G GRIK3 glutamate ionotropic receptor kainate type subunit 3 ISS UniProtKB GO_REF:0000024 NCBI chr 1:36,795,527...37,034,515
Ensembl chr 1:36,795,527...37,034,515
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B IEA Ensembl GO_REF:0000107 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,461,753...77,463,773
Ensembl chr 6:77,461,753...77,463,773
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A IEA Ensembl GO_REF:0000107 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,550...46,897,076
JBrowse link
G NPY2R neuropeptide Y receptor Y2 IEA Ensembl GO_REF:0000107 NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078
JBrowse link
G PLA2G6 phospholipase A2 group VI IEA Ensembl GO_REF:0000107 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19033459 RGD:10413844 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G FMR1 FMRP translational regulator 1 ISS UniProtKB GO_REF:0000024 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,951...147,951,125
Ensembl chr  X:147,911,951...147,951,125
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:111,542,009...111,716,695
Ensembl chr 1:111,542,218...111,716,691
JBrowse link
G RAP1B RAP1B, member of RAS oncogene family IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901
JBrowse link
G RAP1BL RAP1B like (pseudogene) IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:76,170,085...76,174,354 JBrowse link
G SYT4 synaptotagmin 4 IEA Ensembl GO_REF:0000107 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
positive regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY8 adenylate cyclase 8 ISS UniProt GO_REF:0000024 NCBI chr 8:130,780,300...131,041,604
Ensembl chr 8:130,780,301...131,040,909
JBrowse link
G CBLN1 cerebellin 1 precursor IMP (PMID:27418511) UniProtKB PMID:27418511 NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838
JBrowse link
G FMR1 FMRP translational regulator 1 ISO RGD PMID:28894415 RGD:38501107 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,951...147,951,125
Ensembl chr  X:147,911,951...147,951,125
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 IMP (PMID:27418511) UniProtKB PMID:27418511 NCBI chr 4:92,303,622...93,810,415
Ensembl chr 4:92,303,966...93,810,157
JBrowse link
G IQSEC2 IQ motif and Sec7 domain ArfGEF 2 ISO RGD PMID:27009485 RGD:11049506 NCBI chr  X:53,225,784...53,321,356
Ensembl chr  X:53,225,828...53,321,350
JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 ISS UniProtKB GO_REF:0000024 NCBI chr20:49,363,877...49,484,033
Ensembl chr20:49,293,394...49,484,297
JBrowse link
G LILRB2 leukocyte immunoglobulin like receptor B2 ISS (PMID:24052308) ARUK-UCL PMID:24052308 NCBI chr19:54,273,812...54,281,110
Ensembl chr19:54,273,821...54,281,184
JBrowse link
G LILRB3 leukocyte immunoglobulin like receptor B3 ISO (MGI:MGI:5511064|PMID:24052308) ARUK-UCL PMID:24052308 MGI:MGI:5511064 NCBI chr19:54,216,278...54,223,087
Ensembl chr19:54,216,278...54,223,506
JBrowse link
G MAPT microtubule associated protein tau ISO RGD PMID:24298146 RGD:10412705 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A IEA Ensembl GO_REF:0000107 NCBI chr 7:94,907,202...95,296,415
Ensembl chr 7:94,907,202...95,296,415
JBrowse link
G STAU2 staufen double-stranded RNA binding protein 2 ISO RGD PMID:21508097 RGD:10043164 NCBI chr 8:73,420,369...73,747,480
Ensembl chr 8:73,420,369...73,747,708
JBrowse link
regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARC activity regulated cytoskeleton associated protein ISS UniProtKB GO_REF:0000024 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G BCL2L1 BCL2 like 1 ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G DGKI diacylglycerol kinase iota IEA Ensembl GO_REF:0000107 NCBI chr 7:137,381,037...137,846,974
Ensembl chr 7:137,381,037...137,847,092
JBrowse link
G MAPT microtubule associated protein tau TAS (PMID:28386764) ARUK-UCL PMID:28386764 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 ISS
IEA
(PMID:21795692) BHF-UCL
Ensembl
PMID:21795692 GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,298
JBrowse link
G SORCS3 sortilin related VPS10 domain containing receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr10:104,641,290...105,265,242
Ensembl chr10:104,641,290...105,265,242
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    negative regulation of biological process 6172
      negative regulation of signaling 1542
        negative regulation of synaptic transmission 87
          long-term synaptic depression + 36
          negative regulation by symbiont of host synaptic transmission + 0
          negative regulation of excitatory postsynaptic potential + 13
          negative regulation of neuromuscular synaptic transmission 0
          negative regulation of neurotransmitter secretion + 14
          negative regulation of synaptic transmission, GABAergic 8
          negative regulation of synaptic transmission, cholinergic + 2
          negative regulation of synaptic transmission, dopaminergic 4
          negative regulation of synaptic transmission, glutamatergic + 12
          negative regulation of synaptic transmission, glycinergic + 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    cellular process 17686
      cell communication 7249
        cell-cell signaling 2079
          synaptic signaling 995
            trans-synaptic signaling 967
              anterograde trans-synaptic signaling 958
                chemical synaptic transmission 958
                  modulation of chemical synaptic transmission 673
                    negative regulation of synaptic transmission 87
                      long-term synaptic depression + 36
                      negative regulation by symbiont of host synaptic transmission + 0
                      negative regulation of excitatory postsynaptic potential + 13
                      negative regulation of neuromuscular synaptic transmission 0
                      negative regulation of neurotransmitter secretion + 14
                      negative regulation of synaptic transmission, GABAergic 8
                      negative regulation of synaptic transmission, cholinergic + 2
                      negative regulation of synaptic transmission, dopaminergic 4
                      negative regulation of synaptic transmission, glutamatergic + 12
                      negative regulation of synaptic transmission, glycinergic + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.