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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of synaptic transmission
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Accession:GO:0050805 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
Synonyms:exact_synonym: down regulation of synaptic transmission;   downregulation of synaptic transmission
 narrow_synonym: inhibition of synaptic transmission


show annotations for term's descendants           Sort by:
 
negative regulation of synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS		 (PMID:17327472)
GO_REF:0000024		 RGD
UniProt		 PMID:17327472 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adnp activity-dependent neuroprotector homeobox IMP RGD PMID:15963648 RGD:2312778 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Bche butyrylcholinesterase IDA RGD PMID:16275899 RGD:1599456 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:17314300 RGD:1625010 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:17314300 RGD:1625010 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 IDA RGD PMID:17314300 RGD:1625010 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IDA RGD PMID:12604336 RGD:2315497 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gnai1 G protein subunit alpha i1 IMP RGD PMID:11923410 RGD:625670 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:11923410 RGD:625670 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in TAS PMID:16178733 UniProt PMID:16178733 RGD:8554134 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (MGI:5902681|PMID:20739563) RGD PMID:20739563 MGI:5902681 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:15295007 RGD:1642503 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Pcdh17 protocadherin 17 acts_upstream_of_or_within ISO (MGI:5514320|PMID:23684785) RGD PMID:23684785 MGI:5514320 NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 IDA RGD PMID:19734897 RGD:2314692 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Tnr tenascin R involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154583 (MGI:3039956|PMID:15033179)		 Ensembl
RGD		 PMID:15033179 GO_REF:0000107 MGI:3039956 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641 		JBrowse link
long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase acts_upstream_of_or_within ISO (MGI:4829719|PMID:20657592) RGD PMID:20657592 MGI:4829719 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985 		JBrowse link
G Adora1 adenosine A1 receptor acts_upstream_of
involved_in		 ISO
IEA		 MGI:95808 (MGI:5529732|PMID:24259587)
GO_REF:0000107		 RGD
Ensembl		 PMID:24259587 GO_REF:0000107 MGI:5529732 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Arf1 ADP-ribosylation factor 1 involved_in IDA PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:10097163 RGD:2307271 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857158 (MGI:3036431|PMID:14981263)		 Ensembl
RGD		 PMID:14981263 GO_REF:0000107 MGI:3036431 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd5 dopamine receptor D5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3586401|PMID:13679419)		 Ensembl
RGD		 PMID:13679419 GO_REF:0000107 MGI:3586401 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99401 (MGI:5529732|PMID:24259587)		 Ensembl
RGD		 PMID:24259587 GO_REF:0000107 MGI:5529732 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grid2ip Grid2 interacting protein acts_upstream_of_or_within ISO MGI:3796575 (MGI:3796257|PMID:18509461) RGD PMID:18509461 MGI:3796257 NCBI chr12:11,166,567...11,203,765
Ensembl chr12:11,167,874...11,203,676 		JBrowse link
G Mgll monoglyceride lipase acts_upstream_of_or_within ISO (MGI:4829719|PMID:20657592) RGD PMID:20657592 MGI:4829719 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IDA PMID:21252856 UniProt PMID:21252856 RGD:8554238 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Plk2 polo-like kinase 2 involved_in IDA PMID:21382555 UniProt PMID:21382555 RGD:7241548 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prrt1 proline-rich transmembrane protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6446632|PMID:31216424)		 UniProt
RGD		 PMID:31216424 GO_REF:0000024 MGI:6446632 NCBI chr20:4,117,957...4,121,643
Ensembl chr20:4,117,957...4,121,600 		JBrowse link
G Pten phosphatase and tensin homolog IMP NMDA receptor-dependent RGD PMID:20628354 RGD:4144068 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:20826662 RGD:10041066 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5432970|PMID:22699620)		 BHF-UCL
RGD		 PMID:22699620 GO_REF:0000024 MGI:5432970 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5320264|PMID:21795692)		 Ensembl
RGD		 PMID:21795692 GO_REF:0000107 MGI:5320264 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Slc24a1 solute carrier family 24 member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:65,440,842...65,466,001
Ensembl chr 8:65,440,730...65,466,001 		JBrowse link
G Slc24a2 solute carrier family 24 member 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3663782 (MGI:3640012|PMID:16407245)		 RGD PMID:16407245 PMID:21873635 MGI:3640012, RGD:13792537 NCBI chr 5:101,499,536...101,739,337
Ensembl chr 5:101,502,278...101,739,337 		JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 involved_in ISO (MGI:6305031|PMID:27457814) RGD PMID:27457814 MGI:6305031 NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2385465|MGI:2678305 (MGI:3652465|PMID:16600861) RGD PMID:16600861 MGI:3652465 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Stxbp1 syntaxin binding protein 1 acts_upstream_of_or_within ISO MGI:2183278 (MGI:3695670|PMID:17110441) RGD PMID:17110441 MGI:3695670 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln1 cerebellin 1 precursor involved_in ISO (PMID:27418511) RGD PMID:27418511 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Celf4 CUGBP, Elav-like family member 4 acts_upstream_of_or_within ISO MGI:5425630 (MGI:5313512|PMID:21745337) RGD PMID:21745337 MGI:5313512 NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IMP RGD PMID:17632064 RGD:10044262 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (MGI:4941068|PMID:21307259) RGD PMID:21307259 MGI:4941068 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172 		JBrowse link
G Nlgn3 neuroligin 3 involved_in ISO (MGI:5286761|PMID:21808020) RGD PMID:21808020 MGI:5286761 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:12055128 RGD:1642608 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:5320272|PMID:21411674) RGD PMID:21411674 MGI:5320272 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 acts_upstream_of_or_within ISO MGI:2180817 (MGI:2157237|PMID:11553273) RGD PMID:11553273 MGI:2157237 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574 		JBrowse link
G Tmem25 transmembrane protein 25 involved_in IBA
ISO		 PMID:21873635
(MGI:6370252|PMID:31424425)		 RGD PMID:31424425 PMID:21873635 MGI:6370252, RGD:13792537 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389 		JBrowse link
negative regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor acts_upstream_of_or_within ISO MGI:95808 (MGI:5529732|PMID:24259587) RGD PMID:24259587 MGI:5529732 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO ComplexPortal:CPX-1134 (PMID:20739563) RGD PMID:20739563 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2136541|PMID:11438589)		 UniProt
RGD		 PMID:11438589 GO_REF:0000024 MGI:2136541 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syne1 spectrin repeat containing nuclear envelope protein 1 IMP RGD PMID:24191017 RGD:13209020 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322 		JBrowse link
negative regulation of neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (MGI:3841883|PMID:18094106) RGD PMID:18094106 MGI:3841883 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857478|MGI:97321 (MGI:3612345|PMID:16298082)		 Ensembl
RGD		 PMID:16298082 GO_REF:0000107 MGI:3612345 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing involved_in
acts_upstream_of_or_within		 ISO (PMID:25730884)
MGI:2152971|MGI:2152972 (MGI:5634213|PMID:25730884)		 RGD PMID:25730884 MGI:5634213 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 involved_in IMP PMID:16741752 BHF-UCL PMID:16741752 RGD:8554228 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910 		JBrowse link
G Syt4 synaptotagmin 4 involved_in IDA PMID:10397765 ParkinsonsUK-UCL PMID:10397765 RGD:11535116 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of synaptic transmission, dopaminergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16775195 PMID:21873635 RGD:1600308, RGD:13792537 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932 		JBrowse link
G Pmch pro-melanin-concentrating hormone IDA RGD PMID:15555641 RGD:1642493 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18764909 RGD:2300272 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:20730799 RGD:4889470 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
negative regulation of synaptic transmission, GABAergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor NOT IMP
IDA		 in immature hippocampal CA1 neurons
in postnatal 30 day hippocampal CA1 neurons		 RGD PMID:12626609 PMID:12626609 RGD:1625273, RGD:1625273 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Bdnf brain-derived neurotrophic factor acts_upstream_of_or_within ISO (MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:3694324 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:19616018 RGD:2316192 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (MGI:6114325|PMID:28966979) RGD PMID:28966979 MGI:6114325 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA RGD PMID:12533604 RGD:1642497 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17229091 RGD:1626455 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:11796508 RGD:1625505 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 IMP RGD PMID:17317750 RGD:1643193 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Stxbp1 syntaxin binding protein 1 acts_upstream_of_or_within ISO (MGI:3691953|PMID:17167098) RGD PMID:17167098 MGI:3691953 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050342|PMID:21496646)		 UniProt
RGD		 PMID:21496646 GO_REF:0000024 MGI:5050342 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2387895|MGI:2675755 (MGI:3628700|PMID:15489038)
MGI:1857875 (MGI:3610921|PMID:11160501)		 RGD PMID:11160501 PMID:15489038 PMID:21873635 MGI:3610921 MGI:3628700, RGD:13792537 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within IDA
ISO		 MGI:95815 (MGI:3575241|PMID:11985817) RGD PMID:11985817 PMID:17395219 MGI:3575241, RGD:1642466 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:16420445
MGI:95814 (MGI:3575241|PMID:11985817)		 RGD PMID:11985817 PMID:16420445 MGI:3575241, RGD:8554693 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IDA PMID:16420445 UniProt PMID:16420445 RGD:8554693 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 involved_in ISO
IEA		 (MGI:5006896|PMID:21358644)
GO_REF:0000107		 RGD
Ensembl		 PMID:21358644 GO_REF:0000107 MGI:5006896 NCBI chr 2:49,495,771...49,899,702
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17392733 RGD:1626454 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17016851 RGD:1624386 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:27771352 RGD:41412185 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:16190896 RGD:1642508 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:15132431 RGD:6482754 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:5490391|PMID:23616533) RGD PMID:23616533 MGI:5490391 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:894315 (MGI:5490391|PMID:23616533)		 RGD PMID:23616533 PMID:21873635 MGI:5490391, RGD:13792537 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:97852 (MGI:5490391|PMID:23616533)		 RGD PMID:23616533 PMID:21873635 MGI:5490391, RGD:13792537 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:4457852 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
positive regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:1860567|PMID:10864938)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:10864938 GO_REF:0000024 GO_REF:0000107 MGI:1860567 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G App amyloid beta precursor protein involved_in ISO
IC		 (PMID:18568035)
PMID:19242475		 RGD PMID:18568035 PMID:19242475 RGD:151356622 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cbln1 cerebellin 1 precursor involved_in ISO (PMID:27418511) RGD PMID:27418511 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP RGD PMID:28894415 RGD:38501107 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in ISO (PMID:27418511) RGD PMID:27418511 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 IMP RGD PMID:27009485 RGD:11049506 NCBI chr  X:21,254,799...21,337,179
Ensembl chr  X:21,254,914...21,336,584 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5634878|PMID:24494598)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24494598 GO_REF:0000024 GO_REF:0000107 MGI:5634878 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Mapt microtubule-associated protein tau IMP RGD PMID:24298146 RGD:10412705 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Pirb paired Ig-like receptor B involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5511064|PMID:24052308) RGD PMID:24052308 MGI:5511064 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Stau2 staufen double-stranded RNA binding protein 2 IMP RGD PMID:21508097 RGD:10043164 NCBI chr 5:2,840,801...3,084,451
Ensembl chr 5:2,840,765...3,084,929 		JBrowse link
regulation of long-term synaptic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:6148485|PMID:29264923)		 UniProt
RGD		 PMID:29264923 GO_REF:0000024 MGI:6148485 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in IMP PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Dgki diacylglycerol kinase, iota acts_upstream_of_or_within ISO MGI:3584141 (MGI:4936793|PMID:21119615) RGD PMID:21119615 MGI:4936793 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733 		JBrowse link
G Gnal G protein subunit alpha L IMP RGD PMID:31678405 RGD:150429833 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Penk proenkephalin acts_upstream_of_or_within
involved_in		 ISO (PMID:35201898)
(MGI:7260092|PMID:35201898)		 RGD PMID:35201898 MGI:7260092 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5320264|PMID:21795692)		 Ensembl
RGD		 PMID:21795692 PMID:21795692 GO_REF:0000107 MGI:5320264, RGD:7349315 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Sorcs3 sortilin-related VPS10 domain containing receptor 3 acts_upstream_of_or_within ISO MGI:5562419 (MGI:5559089|PMID:24069373) RGD PMID:24069373 MGI:5559089 NCBI chr 1:247,099,178...247,734,027
Ensembl chr 1:247,099,408...247,734,027 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    negative regulation of biological process 5772
      negative regulation of signaling 1504
        negative regulation of synaptic transmission 90
          long-term synaptic depression + 39
          negative regulation by symbiont of host synaptic transmission + 0
          negative regulation of excitatory postsynaptic potential + 12
          negative regulation of neuromuscular synaptic transmission 0
          negative regulation of neurotransmitter secretion + 12
          negative regulation of synaptic transmission, GABAergic 9
          negative regulation of synaptic transmission, cholinergic + 1
          negative regulation of synaptic transmission, dopaminergic 4
          negative regulation of synaptic transmission, glutamatergic + 14
          negative regulation of synaptic transmission, glycinergic + 0
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cell communication 7465
        cell-cell signaling 1766
          synaptic signaling 924
            trans-synaptic signaling 897
              anterograde trans-synaptic signaling 889
                chemical synaptic transmission 889
                  modulation of chemical synaptic transmission 664
                    negative regulation of synaptic transmission 90
                      long-term synaptic depression + 39
                      negative regulation by symbiont of host synaptic transmission + 0
                      negative regulation of excitatory postsynaptic potential + 12
                      negative regulation of neuromuscular synaptic transmission 0
                      negative regulation of neurotransmitter secretion + 12
                      negative regulation of synaptic transmission, GABAergic 9
                      negative regulation of synaptic transmission, cholinergic + 1
                      negative regulation of synaptic transmission, dopaminergic 4
                      negative regulation of synaptic transmission, glutamatergic + 14
                      negative regulation of synaptic transmission, glycinergic + 0
paths to the root