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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of insulin secretion
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Accession:GO:0050796 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the regulated release of insulin.

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regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3803402|PMID:18421434)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18421434 GO_REF:0000024 GO_REF:0000107 MGI:3803402 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO		 GO_REF:0000024
(MGI:4819446|PMID:20562852)		 UniProt
RGD		 PMID:20562852 GO_REF:0000024 MGI:4819446 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465 		JBrowse link
G Cartpt CART prepropeptide IDA RGD PMID:16443761 RGD:2313632 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO
ISS		 (PMID:23979485)
GO_REF:0000024		 RGD
UniProt		 PMID:23979485 GO_REF:0000024 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Cela2a chymotrypsin like elastase 2A involved_in ISS
ISO		 GO_REF:0000024
(PMID:31358993)		 UniProt
RGD		 PMID:31358993 GO_REF:0000024 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782 		JBrowse link
G Clock clock circadian regulator involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4819446|PMID:20562852)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20562852 GO_REF:0000024 GO_REF:0000107 MGI:4819446 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19644453 RGD:2314628 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A IMP RGD PMID:11988095 RGD:1298597 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678 		JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 involved_in IMP PMID:3172165 UniProt PMID:3172165, PMID:3172165 RGD:25671404, RGD:25671404 NCBI chr 6:48,021,771...48,135,241
Ensembl chr 6:48,021,771...48,135,241 		JBrowse link
G Ensa endosulfine alpha involved_in ISO (PMID:9653196) RGD PMID:9653196 NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882 		JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 involved_in ISO (PMID:20668700) RGD PMID:20668700 NCBI chr 3:55,464,528...55,467,170 JBrowse link
G Gcg glucagon involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:5304221|PMID:22037645)
(MGI:3040550|PMID:14736883)
(MGI:3040550|PMID:14736883), (MGI:5304221|PMID:22037645)		 UniProt
RGD		 PMID:14736883 PMID:22037645 GO_REF:0000024 MGI:3040550 MGI:5304221 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650 		JBrowse link
G Gck glucokinase acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:20668700)
MGI:2177703 (MGI:77846|PMID:8530440), (MGI:85404|PMID:8954920)
PMID:21873635		 RGD PMID:8530440 PMID:8954920 PMID:20668700, PMID:21873635, PMID:21873635 MGI:77846 MGI:85404, RGD:13792537, RGD:13792537 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Gip gastric inhibitory polypeptide TAS RGD PMID:8446620 RGD:632885 NCBI chr10:83,835,080...83,848,399
Ensembl chr10:83,840,303...83,848,396 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase involved_in ISS
ISO		 GO_REF:0000024
(MGI:4849622|PMID:20670938)		 UniProt
RGD		 PMID:20670938 GO_REF:0000024 MGI:4849622 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in IEA
ISO		 GO_REF:0000107
(MGI:3575336|PMID:15761495)
GO_REF:0000002		 Ensembl
RGD
InterPro		 PMID:15761495 GO_REF:0000002 GO_REF:0000107 MGI:3575336 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003 		JBrowse link
G Ica1 islet cell autoantigen 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:34,635,509...34,780,187
Ensembl chr 4:34,635,506...34,780,193 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:8383325) RGD PMID:8383325 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA		 (PMID:8383325)
GO_REF:0000107		 RGD
Ensembl		 PMID:8383325 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 involved_in ISO
ISS		 (PMID:22037645)
(MGI:5304221|PMID:22037645)
GO_REF:0000024		 RGD
UniProt		 PMID:22037645 GO_REF:0000024 MGI:5304221 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 involved_in ISO (PMID:15115830) RGD PMID:15115830 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1856424 (MGI:3769319|PMID:16513828) RGD PMID:16513828 MGI:3769319 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G LOC499235 LRRGT00141 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:171,996,406...171,997,611
Ensembl chr 1:171,993,857...171,997,902 		JBrowse link
G Mtnr1b melatonin receptor 1B involved_in ISO (PMID:20668700) RGD PMID:20668700 NCBI chr 8:14,359,270...14,373,894
Ensembl chr 8:14,359,270...14,373,894 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO
IEA		 (PMID:8383325)
GO_REF:0000107		 RGD
Ensembl		 PMID:8383325 GO_REF:0000107 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Pde3b phosphodiesterase 3B acts_upstream_of_or_within ISO (MGI:3040550|PMID:14736883) RGD PMID:14736883 MGI:3040550 NCBI chr 1:183,892,841...184,078,071
Ensembl chr 1:183,892,841...184,078,071 		JBrowse link
G Per2 period circadian regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5319572|PMID:22504074)		 UniProt
RGD		 PMID:22504074 GO_REF:0000024 MGI:5319572 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in ISO
IEA		 (PMID:29768204)
GO_REF:0000107		 RGD
Ensembl		 PMID:29768204 GO_REF:0000107 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in IDA PMID:11978799 UniProt PMID:11978799, PMID:11978799 RGD:8553382, RGD:8553382 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:3713191|PMID:17229940), (MGI:4941444|PMID:20413507) RGD PMID:17229940 PMID:20413507 MGI:3713191 MGI:4941444 NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032)
(MGI:4422104|PMID:20148032)		 RGD PMID:20148032 MGI:4422104 NCBI chr20:32,709,282...32,764,040
Ensembl chr20:32,717,564...32,764,035 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 involved_in ISO (MGI:5465432|PMID:22522610) RGD PMID:22522610 MGI:5465432 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554 		JBrowse link
G Slc8b1 solute carrier family 8 member B1 involved_in ISO
ISS		 (PMID:23056385)
GO_REF:0000024		 RGD
UniProt		 PMID:23056385 GO_REF:0000024 NCBI chr12:41,566,980...41,590,294
Ensembl chr12:41,566,981...41,590,244 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within ISO MGI:2177958 (MGI:3778870|PMID:18178930) RGD PMID:18178930 MGI:3778870 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009 		JBrowse link
G Sstr5 somatostatin receptor 5 acts_upstream_of_or_within
involved_in		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3584184 (MGI:3583838|PMID:15919085)
PMID:21873635		 Ensembl
RGD		 PMID:15919085, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:3583838, RGD:13792537, RGD:13792537 NCBI chr10:14,847,749...14,853,827
Ensembl chr10:14,847,749...14,853,827 		JBrowse link
G Syt7 synaptotagmin 7 involved_in IMP
ISO
ISS		 (MGI:3773625|PMID:18308938)
GO_REF:0000024		 RGD
UniProt		 PMID:18308938, PMID:17709608 GO_REF:0000024 MGI:3773625, RGD:2311143 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377 		JBrowse link
G Syt7_v1 synaptotagmin 7, variant 1 IMP RGD PMID:17709608 RGD:2311143
G Syt9 synaptotagmin 9 IMP RGD PMID:16165130 RGD:2311147 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973 (MGI:3692830|PMID:17046993) RGD PMID:17046993 MGI:3692830 NCBI chr 1:219,126,687...219,139,466
Ensembl chr 1:219,127,602...219,139,464 		JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:15940393), (PMID:19325541)		 UniProt
RGD		 PMID:15940393 PMID:19325541 GO_REF:0000024 NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:8383325) RGD PMID:8383325 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5520038|PMID:22363741)		 UniProt
RGD		 PMID:22363741 GO_REF:0000024 MGI:5520038 NCBI chr20:5,712,200...5,723,902
Ensembl chr20:5,712,203...5,723,902 		JBrowse link
negative regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IDA RGD PMID:15163199 RGD:1598646 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287 		JBrowse link
G Acvr1c activin A receptor type 1C acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:3512292 (MGI:3796011|PMID:18480258)		 Ensembl
RGD		 PMID:18480258 GO_REF:0000107 MGI:3796011 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10952463) RGD PMID:10952463 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Bmp8a bone morphogenetic protein 8a involved_in ISO (PMID:22579288) RGD PMID:22579288 NCBI chr 5:141,007,462...141,033,511
Ensembl chr 5:141,007,462...141,033,511 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5517610|PMID:23705021)		 UniProt
RGD		 PMID:23705021 GO_REF:0000024 MGI:5517610 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024 		JBrowse link
G Chga chromogranin A involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18216393 RGD:2311570 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Enho energy homeostasis associated IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:58,018,039...58,019,836
Ensembl chr 5:58,018,039...58,019,836 		JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D involved_in ISO
ISS		 (PMID:12160727)
GO_REF:0000024		 RGD
UniProt		 PMID:12160727 GO_REF:0000024 NCBI chr15:18,321,757...18,357,252
Ensembl chr15:18,322,327...18,355,818 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide acts_upstream_of_or_within
involved_in		 IDA
ISO		 PMID:17130496
MGI:3709886 (MGI:3709118|PMID:17130496)		 RGD PMID:17130496, PMID:17130496, PMID:17130496 MGI:3709118, RGD:8553721, RGD:8553721 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in IDA PMID:17130496 MGI PMID:17130496, PMID:17130496 RGD:8553721, RGD:8553721 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IMP RGD PMID:17491019 RGD:2302227 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067 		JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:22772764 RGD:9590127 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723 		JBrowse link
G Inhbb inhibin subunit beta B acts_upstream_of_or_within
involved_in		 IEA
ISO
ISS		 GO_REF:0000107
MGI:1857203 (MGI:3796011|PMID:18480258)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18480258 GO_REF:0000024 GO_REF:0000107 MGI:3796011 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in ISO
IEA
IMP		 (PMID:15572028)
GO_REF:0000107
PMID:12435589		 RGD
Ensembl		 PMID:15572028, PMID:12435589, PMID:12435589 GO_REF:0000107, RGD:729325, RGD:729325 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3770494|PMID:17767909)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17767909 GO_REF:0000024 GO_REF:0000107 MGI:3770494 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 involved_in ISO (PMID:8923010) RGD PMID:8923010 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IDA RGD PMID:16133261 RGD:1581603 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339 		JBrowse link
G Midn midnolin involved_in IDA PMID:24187134 MGI PMID:24187134, PMID:24187134 RGD:8655525, RGD:8655525 NCBI chr 7:12,414,303...12,426,712
Ensembl chr 7:12,414,733...12,424,367 		JBrowse link
G Mtnr1a melatonin receptor 1A IMP RGD PMID:22288848 RGD:9686057 NCBI chr16:50,339,358...50,358,809
Ensembl chr16:50,339,358...50,358,809 		JBrowse link
G Mtnr1b melatonin receptor 1B IMP RGD PMID:18363673 RGD:9588673 NCBI chr 8:14,359,270...14,373,894
Ensembl chr 8:14,359,270...14,373,894 		JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:17130471 RGD:1642149 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Npff neuropeptide FF-amide peptide precursor IDA RGD PMID:1704109 RGD:2316580 NCBI chr 7:144,127,084...144,127,873
Ensembl chr 7:144,127,085...144,127,873 		JBrowse link
G Pde8b phosphodiesterase 8B IMP RGD PMID:17991719 RGD:2312519 NCBI chr 2:24,718,548...24,955,533
Ensembl chr 2:24,719,976...24,923,128 		JBrowse link
G Pfkl phosphofructokinase, liver type acts_upstream_of_or_within ISO (MGI:1096000|PMID:9287040) RGD PMID:9287040 MGI:1096000 NCBI chr20:11,393,860...11,415,889
Ensembl chr20:11,393,877...11,415,882 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IMP PMID:19965390 BHF-UCL PMID:19965390, PMID:19965390 RGD:2316628, RGD:2316628 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:24187134)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:24187134 GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 involved_in IMP PMID:16099819 BHF-UCL PMID:16099819, PMID:16099819 RGD:8554418, RGD:8554418 NCBI chr12:38,786,539...38,805,121
Ensembl chr12:38,786,540...38,805,121 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IDA RGD PMID:10531320 RGD:10043332 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:3522021 (MGI:3513751|PMID:15520383) RGD PMID:15520383 MGI:3513751 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
ISS		 (PMID:20942606)
GO_REF:0000024		 RGD
UniProt		 PMID:20942606 GO_REF:0000024 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (MGI:5619445|PMID:23092880) RGD PMID:23092880 MGI:5619445 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17994217)		 Ensembl
RGD		 PMID:17994217 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777 		JBrowse link
G Sirt4 sirtuin 4 acts_upstream_of_or_within
involved_in		 ISO (PMID:17715127)
MGI:3769237|MGI:95753 (MGI:3769241|PMID:16959573)		 RGD PMID:16959573 PMID:17715127 MGI:3769241 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within ISO MGI:2177773 (MGI:3770077|PMID:16890542) RGD PMID:16890542 MGI:3770077 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009 		JBrowse link
G Stxbp5l syntaxin binding protein 5-like acts_upstream_of_or_within ISO (MGI:5296997|PMID:21998599) RGD PMID:21998599 MGI:5296997 NCBI chr11:66,246,624...66,566,331
Ensembl chr11:66,316,606...66,566,331 		JBrowse link
G Sytl4 synaptotagmin-like 4 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3770077|PMID:16890542)		 Ensembl
RGD		 PMID:16890542 GO_REF:0000107 MGI:3770077 NCBI chr  X:104,763,961...104,814,152
Ensembl chr  X:104,765,294...104,814,145 		JBrowse link
G Uts2 urotensin 2 IMP RGD PMID:17931748 RGD:2306798 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145 		JBrowse link
G Vsnl1 visinin-like 1 acts_upstream_of_or_within ISO (MGI:3694336|PMID:16731532) RGD PMID:16731532 MGI:3694336 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023 		JBrowse link
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067882.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 9:70,787,136...70,787,913 JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IMP		 (PMID:19965390) RGD PMID:19965390, PMID:19965390, PMID:19965390 RGD:2316628, RGD:2316628 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17360501 RGD:2306172 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362 		JBrowse link
G Eny2 ENY2, transcription and export complex 2 subunit IMP RGD PMID:22649445 RGD:9590329 NCBI chr 7:83,348,656...83,358,430
Ensembl chr 7:83,348,694...83,357,492 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B acts_upstream_of_or_within ISO MGI:2182644 (MGI:4421103|PMID:19805579) RGD PMID:19805579 MGI:4421103 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:20610886 RGD:5508687 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Jagn1 jagunal homolog 1 IMP RGD PMID:26882284 RGD:11520872 NCBI chr 4:145,399,885...145,404,605
Ensembl chr 4:145,399,913...145,404,617 		JBrowse link
G Klf7 Kruppel like factor 7 involved_in ISO (PMID:16339272) RGD PMID:16339272 NCBI chr 9:70,740,480...70,787,913
Ensembl chr 9:70,740,480...70,787,913 		JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr 5:77,338,853...77,342,299
Ensembl chr 5:77,338,853...77,342,299 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 IMP RGD PMID:19690174 RGD:7495848 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545 		JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 acts_upstream_of_or_within ISO (MGI:5467193|PMID:22587331) RGD PMID:22587331 MGI:5467193 NCBI chr 2:39,322,145...39,434,535
Ensembl chr 2:39,321,741...39,434,560 		JBrowse link
G Pde1c phosphodiesterase 1C IMP RGD PMID:18706893 RGD:2302857 NCBI chr 4:86,359,762...86,925,044
Ensembl chr 4:86,359,820...86,630,543 		JBrowse link
G Pde3b phosphodiesterase 3B IMP RGD PMID:18706893 RGD:2302857 NCBI chr 1:183,892,841...184,078,071
Ensembl chr 1:183,892,841...184,078,071 		JBrowse link
G Pde4c phosphodiesterase 4C IMP RGD PMID:18706893 RGD:2302857 NCBI chr16:20,442,305...20,466,386
Ensembl chr16:20,442,609...20,460,959
Ensembl chr16:20,442,609...20,460,959 		JBrowse link
G Pde8b phosphodiesterase 8B IMP RGD PMID:18706893 RGD:2302857 NCBI chr 2:24,718,548...24,955,533
Ensembl chr 2:24,719,976...24,923,128 		JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294526|PMID:21099329)		 UniProt
RGD		 PMID:21099329 GO_REF:0000024 MGI:5294526 NCBI chr 7:129,856,467...129,863,441
Ensembl chr 7:129,860,114...129,863,441 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 IMP RGD PMID:20167843 RGD:12904047 NCBI chr 3:79,734,961...79,743,737
Ensembl chr 3:79,734,961...79,743,737 		JBrowse link
G Ucp2 uncoupling protein 2 IMP RGD PMID:21172424 RGD:7204422 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744 		JBrowse link
positive regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:17724028, PMID:21873635, PMID:21873635 RGD:2301019, RGD:13792537, RGD:13792537 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694 		JBrowse link
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:20695849 RGD:9588550 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 involved_in IMP PMID:23766516 UniProt PMID:23766516, PMID:23766516 RGD:14695075, RGD:14695075 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO		 GO_REF:0000024
(MGI:3778846|PMID:18223655)		 UniProt
RGD		 PMID:18223655 GO_REF:0000024 MGI:3778846 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:19667185) RGD PMID:19667185 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653 		JBrowse link
G Capn10 calpain 10 involved_in ISO
IEA		 (PMID:15471947)
GO_REF:0000107		 RGD
Ensembl		 PMID:15471947 GO_REF:0000107 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase IMP RGD PMID:24140090 RGD:11576293 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155 		JBrowse link
G Casr calcium-sensing receptor IMP RGD PMID:22566534 RGD:7205453 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771 		JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:9664081 RGD:2307276 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672 		JBrowse link
G Doc2b double C2 domain beta involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4457249|PMID:17548353)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17548353 GO_REF:0000024 GO_REF:0000107 MGI:4457249 NCBI chr10:63,921,255...63,952,944
Ensembl chr10:63,928,064...63,952,726 		JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in IMP
ISO
IEA
ISS		 (MGI:5607397|PMID:24130766)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24130766, PMID:16081037 GO_REF:0000024 GO_REF:0000107 MGI:5607397, RGD:2315053 NCBI chr 1:89,308,475...89,309,379
Ensembl chr 1:89,308,475...89,309,379 		JBrowse link
G Gck glucokinase acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA
ISS		 (MGI:76949|PMID:7556622)
(MGI:3819280|PMID:18477811)
GO_REF:0000107
(PMID:8132752), (PMID:8878425)
GO_REF:0000024
(MGI:3819280|PMID:18477811), (MGI:76949|PMID:7556622)
in response to glucose stimulation		 RGD
Ensembl
UniProt		 PMID:7556622 PMID:8132752 PMID:8878425 PMID:18477811, PMID:17028192, PMID:17360975 GO_REF:0000024 GO_REF:0000107 MGI:3819280 MGI:76949, RGD:1581879, RGD:2301916 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in IDA PMID:11756331 UniProt PMID:11756331, PMID:11756331 RGD:8554453, RGD:8554453 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Gip gastric inhibitory polypeptide IMP RGD PMID:8958204 RGD:2312537 NCBI chr10:83,835,080...83,848,399
Ensembl chr10:83,840,303...83,848,396 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor IMP RGD PMID:11014226 RGD:2312607 NCBI chr 1:80,063,047...80,073,223
Ensembl chr 1:80,063,049...80,073,223 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:24301293 RGD:8662441 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:12093887 RGD:625448 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228 		JBrowse link
G Glrx glutaredoxin IMP RGD PMID:19299446 RGD:9686053 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944 		JBrowse link
G Glud1 glutamate dehydrogenase 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:11502802)
MGI:1922637 (MGI:3769241|PMID:16959573)		 RGD PMID:11502802 PMID:16959573 MGI:3769241 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557 		JBrowse link
G Glul glutamate-ammonia ligase IMP ornithine alpha-ketoglutarate-induced secretion RGD PMID:12575909 RGD:2301557 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5141337|PMID:21673097)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21673097 GO_REF:0000024 GO_REF:0000107 MGI:5141337 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (MGI:4355293|PMID:19213841) RGD PMID:19213841 MGI:4355293 NCBI chr13:42,008,642...42,220,737
Ensembl chr13:42,008,842...42,009,738 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:5445001 (MGI:5444590|PMID:22733973) RGD PMID:22733973 MGI:5444590 NCBI chr 6:124,874,151...124,903,949
Ensembl chr 6:124,874,151...124,876,710 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) RGD PMID:15572028 MGI:4456946 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684 		JBrowse link
G Isl1 ISL LIM homeobox 1 IMP RGD PMID:11978636 RGD:729103 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Jak2 Janus kinase 2 IMP in response to human growth hormone RGD PMID:16597920 RGD:1641815 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,801,544...8,829,506
Ensembl chr 3:8,802,852...8,828,533 		JBrowse link
G Mcu mitochondrial calcium uniporter involved_in ISO (PMID:22829870) RGD PMID:22829870 NCBI chr20:29,037,452...29,199,224
Ensembl chr20:29,038,480...29,199,224 		JBrowse link
G Myrip myosin VIIA and Rab interacting protein involved_in IMP PMID:17827149 UniProt PMID:17827149, PMID:17827149 RGD:8554303, RGD:8554303 NCBI chr 8:128,972,307...129,139,257
Ensembl chr 8:128,972,311...129,139,251 		JBrowse link
G Nkx6-1 NK6 homeobox 1 IMP RGD PMID:15883383 RGD:2306242 NCBI chr14:9,555,264...9,562,197
Ensembl chr14:9,555,264...9,562,189 		JBrowse link
G Nlgn2 neuroligin 2 involved_in IDA
ISO
IEA
IMP		 (PMID:22528485)
GO_REF:0000107		 RGD
Ensembl		 PMID:22528485, PMID:22528485, PMID:18755801 GO_REF:0000107, RGD:9743981, RGD:2314456 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847 		JBrowse link
G Nnat neuronatin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3614320|PMID:15793245)
PMID:21873635		 RGD PMID:15793245, PMID:21873635, PMID:21873635 MGI:3614320, RGD:13792537, RGD:13792537 NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 IMP RGD PMID:17259388 RGD:2311606 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319 		JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:17095531 RGD:2305956 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IMP RGD PMID:19635791 RGD:7242950 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:18439098 RGD:2306975 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IDA RGD PMID:16980436 RGD:2304071 NCBI chr13:47,413,453...47,440,682
Ensembl chr13:47,413,458...47,440,682 		JBrowse link
G Pfkm phosphofructokinase, muscle acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:3759504 (MGI:3759009|PMID:17595219)		 Ensembl
RGD		 PMID:17595219 GO_REF:0000107 MGI:3759009 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within ISO (MGI:2675178|PMID:12837755) RGD PMID:12837755 MGI:2675178 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 involved_in IDA PMID:10567574 BHF-UCL PMID:10567574, PMID:10567574 RGD:633869, RGD:633869 NCBI chr12:38,786,539...38,805,121
Ensembl chr12:38,786,540...38,805,121 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 IMP RGD PMID:15039777 RGD:10045958 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (PMID:16034410) RGD PMID:16034410 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) involved_in ISO (MGI:3044444|PMID:15159548) RGD PMID:15159548 MGI:3044444 NCBI chr10:63,989,556...64,140,584
Ensembl chr10:63,989,644...64,108,554 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 acts_upstream_of_or_within ISO MGI:3652355 (MGI:3619104|PMID:16415102) RGD PMID:16415102 MGI:3619104 NCBI chr 2:148,718,279...148,722,263
Ensembl chr 2:148,718,280...148,722,263 		JBrowse link
G Sirt3 sirtuin 3 IMP RGD PMID:23397292 RGD:9586042 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546 		JBrowse link
G Slc30a8 solute carrier family 30 member 8 involved_in IMP PMID:19479076 BHF-UCL PMID:19479076, PMID:19479076 RGD:2315022, RGD:2315022 NCBI chr 7:91,832,988...91,869,329
Ensembl chr 7:91,832,988...91,867,300 		JBrowse link
G Snap25 synaptosome associated protein 25 IEP RGD PMID:15042624 RGD:1581081 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:3819280|PMID:18477811) RGD PMID:18477811 MGI:3819280 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Tardbp TAR DNA binding protein IMP RGD PMID:21127054 RGD:7243008 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:19386626)
(MGI:4412432|PMID:19168596)		 RGD PMID:19168596 PMID:19386626 MGI:4412432 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514 		JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 involved_in ISO
ISS		 (PMID:21853325)
GO_REF:0000024		 RGD
UniProt		 PMID:21853325 GO_REF:0000024 NCBI chr 4:180,913,703...180,951,564
Ensembl chr 4:180,913,706...180,951,564 		JBrowse link
G Trh thyrotropin releasing hormone involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16118471, PMID:21873635, PMID:21873635 RGD:1600419, RGD:13792537, RGD:13792537 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IMP RGD PMID:16601673 RGD:9999436 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051 		JBrowse link
G Ucn3 urocortin 3 IMP RGD PMID:17360501 RGD:2306172 NCBI chr17:69,959,879...69,966,532
Ensembl chr17:69,960,160...69,966,099 		JBrowse link
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 IMP RGD PMID:29540530 RGD:41404656 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in ISS
ISO
IEA
IMP		 GO_REF:0000024
(MGI:5636119|PMID:25403481)
GO_REF:0000107
PMID:21046358		 UniProt
RGD
Ensembl		 PMID:25403481, PMID:21046358, PMID:21046358 GO_REF:0000024 GO_REF:0000107 MGI:5636119, RGD:8553299, RGD:8553299 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804 		JBrowse link
G Ano1 anoctamin 1 involved_in ISO UniProtKB:P13569 (PMID:24885604)
(MGI:5640937|PMID:24885604)		 RGD PMID:24885604 MGI:5640937 NCBI chr 1:217,754,349...217,902,540
Ensembl chr 1:217,754,336...217,902,473 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in ISO (MGI:4453294|PMID:19915011) RGD PMID:19915011 MGI:4453294 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:3587769 (MGI:5544155|PMID:24105478) RGD PMID:24105478 MGI:5544155 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO (MGI:3778846|PMID:18223655) RGD PMID:18223655 MGI:3778846 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Baiap3 BAI1-associated protein 3 involved_in ISO (PMID:28626000) RGD PMID:28626000 NCBI chr10:14,601,133...14,613,881
Ensembl chr10:14,599,197...14,613,878 		JBrowse link
G C1qtnf12 C1q and TNF related 12 acts_upstream_of_or_within ISO (MGI:5317500|PMID:22275362) RGD PMID:22275362 MGI:5317500 NCBI chr 5:173,390,901...173,395,276
Ensembl chr 5:173,390,901...173,395,276 		JBrowse link
G C2cd2l C2CD2-like acts_upstream_of_or_within
involved_in		 ISO (PMID:28209843)
(MGI:5522601|PMID:24012759)		 RGD PMID:24012759 PMID:28209843 MGI:5522601 NCBI chr 8:48,641,792...48,652,119
Ensembl chr 8:48,641,801...48,652,071 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IMP RGD PMID:23229155 RGD:13506727 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:156,876,706...156,878,486
Ensembl chr 5:156,876,706...156,878,486 		JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO		 GO_REF:0000107
(MGI:5640937|PMID:24885604)
UniProtKB:Q5XXA6 (PMID:24885604)		 Ensembl
RGD		 PMID:24885604 GO_REF:0000107 MGI:5640937 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Cltrn collectrin, amino acid transport regulator involved_in ISO
IBA		 (PMID:16330323)
PMID:21873635		 RGD PMID:16330323, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr  X:32,118,082...32,153,687
Ensembl chr  X:32,118,054...32,153,794 		JBrowse link
G Crh corticotropin releasing hormone IDA RGD PMID:20080775 RGD:5508172 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 IDA RGD PMID:17130471 RGD:1642149 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572 		JBrowse link
G Gcg glucagon involved_in IEA
ISO
IBA		 GO_REF:0000107
(MGI:4453294|PMID:19915011)
PMID:21873635		 Ensembl
RGD		 PMID:19915011, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:4453294, RGD:13792537, RGD:13792537 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:16647196 RGD:12905046 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448527|PMID:20153004)		 UniProt
RGD		 PMID:20153004 GO_REF:0000024 MGI:5448527 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678 		JBrowse link
G Gpr27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (MGI:5311513|PMID:22253604) RGD PMID:22253604 MGI:5311513 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3701833 (MGI:4437975|PMID:19213833) RGD PMID:19213833 MGI:4437975 NCBI chr13:42,008,642...42,220,737
Ensembl chr13:42,008,842...42,009,738 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:5445001 (MGI:5444590|PMID:22733973) RGD PMID:22733973 MGI:5444590 NCBI chr 6:124,874,151...124,903,949
Ensembl chr 6:124,874,151...124,876,710 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:2677892 (MGI:4459348|PMID:20440072)		 Ensembl
RGD		 PMID:20440072 GO_REF:0000107 MGI:4459348 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Kif5b kinesin family member 5B IMP RGD PMID:25462067 RGD:11059539 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096 		JBrowse link
G Lepr leptin receptor IDA RGD PMID:9751766 RGD:10412039 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221 		JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:24865476 RGD:13800516 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within ISO MGI:5635078 (MGI:5576400|PMID:24910426) RGD PMID:24910426 MGI:5576400 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:23354122 RGD:12798521 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625 		JBrowse link
G Nadk NAD kinase IMP RGD PMID:22550069 RGD:13703105 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 IMP RGD PMID:16738321 RGD:9590126 NCBI chr 3:150,919,317...150,990,391
Ensembl chr 3:150,919,317...150,960,030 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4457989|PMID:20447400)		 Ensembl
RGD		 PMID:20447400 GO_REF:0000107 MGI:4457989 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Osbp oxysterol binding protein IMP RGD PMID:29540530 RGD:41404656 NCBI chr 1:228,395,237...228,425,366
Ensembl chr 1:228,395,558...228,425,361 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IMP RGD PMID:20460097 RGD:2326185 NCBI chr 2:53,859,738...54,007,733
Ensembl chr 2:53,859,737...54,007,756 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (MGI:5311513|PMID:22253604) RGD PMID:22253604 MGI:5311513 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213 		JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in IMP PMID:20501872 BHF-UCL PMID:20501872, PMID:20501872 RGD:8554604, RGD:8554604 NCBI chr 3:2,797,037...2,798,436
Ensembl chr 3:2,796,997...2,798,470 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
ISO		 (MGI:3778607|PMID:17895289) RGD PMID:17895289, PMID:11278673 MGI:3778607, RGD:6482760 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:19965574 RGD:2324877 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in IMP
ISO
IEA		 PMID:11978799
(MGI:5306323|PMID:11978799)
GO_REF:0000107		 RGD
Ensembl		 PMID:11978799, PMID:11978799, PMID:11978799 GO_REF:0000107 MGI:5306323, RGD:8553382, RGD:8553382 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IMP
ISO		 (MGI:5489045|PMID:23412604) RGD PMID:23412604, PMID:23412604 MGI:5489045, RGD:14392803 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:25497100) RGD PMID:25497100 NCBI chr20:32,709,282...32,764,040
Ensembl chr20:32,717,564...32,764,035 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:21484216) RGD PMID:21484216 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:16366736 RGD:9585658 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) RGD PMID:22338092 MGI:5487506 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983 		JBrowse link
G Stx4 syntaxin 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12855681), (PMID:24552216)		 Ensembl
RGD		 PMID:12855681 PMID:24552216 GO_REF:0000107 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979 		JBrowse link
G Sybu syntabulin IMP RGD PMID:22975310 RGD:8554225 NCBI chr 7:83,600,614...83,670,121
Ensembl chr 7:83,600,617...83,670,356 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP RGD PMID:22701540 RGD:10043784 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:16806463 RGD:10003029 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960 		JBrowse link
G Vsnl1 visinin-like 1 acts_upstream_of_or_within ISO (MGI:3694336|PMID:16731532) RGD PMID:16731532 MGI:3694336 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023 		JBrowse link
regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034833.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr12:53,872...54,885 JBrowse link
G AABR07071701.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 8:126,975,833...126,976,850 JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6394227|PMID:32072744)		 Ensembl
RGD		 PMID:32072744 GO_REF:0000107 MGI:6394227 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028 		JBrowse link
G Adcy5 adenylate cyclase 5 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:24740569)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24740569 GO_REF:0000024 GO_REF:0000107 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:3046203 (MGI:4355257|PMID:19644667)		 Ensembl
RGD		 PMID:19644667 GO_REF:0000107 MGI:4355257 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISO
IEA		 (PMID:22669945)
(MGI:5448801|PMID:22798068)
GO_REF:0000107		 RGD
Ensembl		 PMID:22669945 PMID:22798068 GO_REF:0000107 MGI:5448801 NCBI chr 1:214,918,757...214,940,883
Ensembl chr 1:214,927,172...214,947,624 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E acts_upstream_of_or_within ISO MGI:3526823 (MGI:3525921|PMID:15630454), (MGI:3526670|PMID:11923483) RGD PMID:11923483 PMID:15630454 MGI:3525921 MGI:3526670 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980 		JBrowse link
G Cdk16 cyclin-dependent kinase 16 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5448801|PMID:22798068)
GO_REF:0000024
(PMID:22798068)		 Ensembl
RGD
UniProt		 PMID:22798068 GO_REF:0000024 GO_REF:0000107 MGI:5448801 NCBI chr  X:1,707,285...1,718,821
Ensembl chr  X:1,707,289...1,718,637 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 NOT
NOT|involved_in		 IMP PMID:21494687 ParkinsonsUK-UCL PMID:21494687, PMID:21494687 RGD:11567254, RGD:11567254 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828 		JBrowse link
G Efna5 ephrin A5 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5294297|PMID:17448994)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17448994 GO_REF:0000024 GO_REF:0000107 MGI:5294297 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486 		JBrowse link
G Epha5 EPH receptor A5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294297|PMID:17448994)		 UniProt
RGD		 PMID:17448994 GO_REF:0000024 MGI:5294297 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227 		JBrowse link
G Foxa2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) RGD PMID:11875061 MGI:5142372 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000002
MGI:4366465 (MGI:4366217|PMID:19651901)		 InterPro
RGD		 PMID:19651901 GO_REF:0000002 MGI:4366217 NCBI chr 8:90,628,203...90,665,055
Ensembl chr 8:90,628,209...90,664,554 		JBrowse link
G LOC102554748 nidogen-2-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:380,313...427,615
Ensembl chr 7:380,741...381,732 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2448955 (MGI:2448205|PMID:12509515)
PMID:21873635		 RGD PMID:12509515, PMID:21873635, PMID:21873635 MGI:2448205, RGD:13792537, RGD:13792537 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094 		JBrowse link
G Mir130a microRNA 130a acts_upstream_of_or_within ISO (MGI:4819076|PMID:20417623) RGD PMID:20417623 MGI:4819076 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124 		JBrowse link
G Mir200a microRNA 200a acts_upstream_of_or_within ISO (MGI:4819076|PMID:20417623) RGD PMID:20417623 MGI:4819076 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir410 microRNA 410 acts_upstream_of_or_within ISO (MGI:4819076|PMID:20417623) RGD PMID:20417623 MGI:4819076 NCBI chr 6:133,893,997...133,894,072
Ensembl chr 6:133,893,993...133,894,073 		JBrowse link
G Myt1 myelin transcription factor 1 acts_upstream_of_or_within ISO (MGI:3763794|PMID:17928203) RGD PMID:17928203 MGI:3763794 NCBI chr 3:177,281,365...177,341,550
Ensembl chr 3:177,310,753...177,341,547 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5313784|PMID:22166979)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22166979 GO_REF:0000024 GO_REF:0000107 MGI:5313784 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO (PMID:20447400) RGD PMID:20447400 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Nrxn1 neurexin 1 acts_upstream_of_or_within ISO MGI:3042794 (MGI:5315831|PMID:22235116) RGD PMID:22235116 MGI:5315831 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660 		JBrowse link
G Piwil4 piwi-like RNA-mediated gene silencing 4 involved_in IMP PMID:28711973 UniProt PMID:28711973, PMID:28711973 RGD:13800537, RGD:13800537 NCBI chr 8:13,208,774...13,251,970
Ensembl chr 8:13,208,774...13,251,812 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within ISO MGI:2680163 (MGI:4367975|PMID:19401415) RGD PMID:19401415 MGI:4367975 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:5532825 (MGI:5529865|PMID:23776622)		 Ensembl
RGD		 PMID:23776622 GO_REF:0000107 MGI:5529865 NCBI chr 8:50,230,335...50,246,979
Ensembl chr 8:50,230,339...50,246,656 		JBrowse link
G Slc9b2 solute carrier family 9 member B2 involved_in ISO (MGI:5492253|PMID:23720317) RGD PMID:23720317 MGI:5492253 NCBI chr 2:240,485,254...240,519,166
Ensembl chr 2:240,495,371...240,519,141 		JBrowse link
G Stxbp4 syntaxin binding protein 4 involved_in ISO (PMID:12855681) RGD PMID:12855681 NCBI chr10:78,005,745...78,168,641
Ensembl chr10:78,009,338...78,168,609 		JBrowse link
G Sybu syntabulin involved_in IDA PMID:22975310 MGI PMID:22975310, PMID:22975310 RGD:8554225, RGD:8554225 NCBI chr 7:83,600,614...83,670,121
Ensembl chr 7:83,600,617...83,670,356 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:4412432|PMID:19168596) RGD PMID:19168596 MGI:4412432 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:18930714 RGD:10043296 NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103 		JBrowse link
G Ufm1 ubiquitin-fold modifier 1 NOT
NOT|involved_in		 IMP PMID:21494687 ParkinsonsUK-UCL PMID:21494687, PMID:21494687 RGD:11567254, RGD:11567254 NCBI chr 2:143,096,268...143,104,412
Ensembl chr 2:143,096,271...143,104,412 		JBrowse link
G Zbed6 zinc finger, BED-type containing 6 involved_in ISO (MGI:6120647|PMID:29440408) RGD PMID:29440408 MGI:6120647 NCBI chr13:50,196,143...50,211,670 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      regulation of cellular process 12625
        regulation of secretion by cell 730
          regulation of protein secretion 321
            regulation of insulin secretion 209
              negative regulation of insulin secretion + 55
              positive regulation of insulin secretion + 98
              regulation of insulin secretion involved in cellular response to glucose stimulus + 97
Path 2
Term Annotations click to browse term
  biological_process 20082
    localization 6506
      establishment of localization 4918
        transport 4755
          ion transport 3516
            anion transport 2698
              organic substance transport 2574
                peptide transport 1762
                  peptide secretion 472
                    protein secretion 415
                      insulin secretion 248
                        regulation of insulin secretion 209
                          negative regulation of insulin secretion + 55
                          positive regulation of insulin secretion + 98
                          regulation of insulin secretion involved in cellular response to glucose stimulus + 97
paths to the root