Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.
Synonyms:
exact_synonym:
down regulation of thymidylate synthase biosynthetic process; downregulation of thymidylate synthase biosynthetic process; negative regulation of thymidylate synthase anabolism; negative regulation of thymidylate synthase biosynthesis; negative regulation of thymidylate synthase formation; negative regulation of thymidylate synthase synthesis
narrow_synonym:
inhibition of thymidylate synthase biosynthetic process